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anti-Mouse (Murine) BIRC2 Antibodies:
anti-Human BIRC2 Antibodies:
anti-Rat (Rattus) BIRC2 Antibodies:
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Dog (Canine) Polyclonal BIRC2 Primary Antibody for IHC (fro), IHC (p) - ABIN537405
Lin, Chang, Ho, Huang: Ischemic preconditioning reduces neurovascular damage after hypoxia-ischemia via the cellular inhibitor of apoptosis 1 in neonatal brain. in Stroke; a journal of cerebral circulation 2012
Dog (Canine) Polyclonal BIRC2 Primary Antibody for IHC (fro), IHC (p) - ABIN4298716
Chui, Ma, Li, Xu, Yao, Lin, Chan, Lee: Anti-apoptotic protein BRE/BRCC45 attenuates apoptosis through maintaining the expression of caspase inhibitor XIAP in mouse Lewis lung carcinoma D122 cells. in Apoptosis : an international journal on programmed cell death 2014
We show that BIRC3 (show BIRC3 Antibodies) has a unique role in facilitating glioma progression from low- to high-grade
These findings reveal a novel mechanism that endotoxin tolerance reprograms mitogen-activated protein kinase (show MAPK1 Antibodies) signaling by suppressing Pellino 1 (show PELI1 Antibodies)-mediated K63-linked ubiquitination of cIAP2 (show BIRC3 Antibodies), K48-linked ubiquitination, and degradation of TRAF3 (show TRAF3 Antibodies).
Birc3 (show BIRC3 Antibodies)-deficient mice are resistant to azoxymethane-sodium dodecyl sulfate-induced colitis-associated colorectal cancer.
c-IAP (show ALPI Antibodies) ubiquitin protein ligase (show UBE2K Antibodies) activity is required for 4-1BB (show TNFRSF9 Antibodies) signaling and CD8 (show CD8A Antibodies)(+) memory T-cell survival.
Induction of cIAP2 expression upon microglia activation prevents the conversion of caspase-3 p19 subunit to p17 subunit.
Results identify IGF2BP1 (show B4GALNT2 Antibodies) as a critical translational regulator of cIAP1-mediated apoptotic resistance in rhabdomyosarcoma.
we show that cIAP1 regulates TNF (show TNF Antibodies)-induced actin cytoskeleton reorganization through a cdc42 (show CDC42 Antibodies)-dependentpathway
Identify xIAP (show XIAP Antibodies) and cIAP1 as molecular targets of ceramide and show ceramide analog LCL85 is an effective sensitizer in overcoming resistance of metastatic colon and breast cancers to apoptosis induction to suppress metastasis in vivo.
cIAP2 (Birc3 (show BIRC3 Antibodies))-dependent antagonism of RIPK3 (show RIPK3 Antibodies)-mediated programmed necrosis critically protects the host from influenza infection through maintenance of pulmonary tissue homeostasis.
cIAP-2 (show BIRC3 Antibodies) protects cardiac fibroblasts from oxidative damage: an obligate regulatory role for ERK1/2 (show MAPK1/3 Antibodies) MAPK (show MAPK1 Antibodies) and NF-kappaB (show NFKB1 Antibodies).
High cIAP1 expression is associated with Lung Tumorigenesis.
These data suggest that molluscum contagiosum virus MC159 competitively binds to NEMO (show IKBKG Antibodies) to prevent cIAP1-induced NEMO (show IKBKG Antibodies) polyubiquitination.
The baseline tumor necrosis factor (show TNF Antibodies) tumor (TNFalpha (show TNF Antibodies)) expression correlates with the sensitivity to Inhibitors of apoptosis proteins (IAPs) antagonist T-3256336.
cIAP1-induced mitophagy led to dysfunctional mitochondria that resulted in abrogation of mitochondrial oxygen consumption rate along with the decrease in ATP levels. The ubiquitination of cIAP1 was found to be the critical regulator of mitophagy.
Overexpression of cIAP1 is associated with glioma.
High expression of cIAP1 is associated with triple-negative breast cancer.
cIAP1 and cIAP2 (show BIRC3 Antibodies) mediate BCL10 (show BCL10 Antibodies) ubiquitination essential for BCR (show BCR Antibodies)-dependent NF-kB activity in the ABC (show ABCB6 Antibodies) subtype of DLBCL. cIAP1/2 attach K63-linked polyubiquitin (show UBB Antibodies) chains on themselves and on BCL10 (show BCL10 Antibodies), recruiting IKK (show CHUK Antibodies) and LUBAC essential for IKK (show CHUK Antibodies) activation.
AZD5582 draws Mcl-1 (show MCL1 Antibodies) down-regulation for induction of apoptosis through targeting of cIAP1 and XIAP (show XIAP Antibodies) in human pancreatic cancer
Data indicate that Smac/DIABLO (show DIABLO Antibodies) showed an inverse correlation with inhibitor of apoptosis proteins XIAP (show XIAP Antibodies), cIAP-1 and cIAP-2 (show BIRC3 Antibodies).
Data show that ectopic expression of interferon regulatory factor 1 (IRF-1 (show IRF1 Antibodies)) reduces NF-kappa B (show NFKB1 Antibodies) activity and suppresses TNF receptor-associated factor 2 (TRAF2 (show TRAF2 Antibodies)) and inhibitor of apoptosis 1 protein (cIAP1) expression in breast cancer cells.
The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
, apoptosis inhibitor 1
, baculoviral IAP repeat-containing 2
, baculoviral IAP repeat-containing protein 3
, inhibitor of apoptosis protein 1
, inhibitor of apoptosis protein-1
, IAP homolog B
, NFR2-TRAF signalling complex protein
, RING finger protein 48
, TNFR2-TRAF-signaling complex protein 2
, baculoviral IAP repeat-containing protein 2
, inhibitor of apoptosis protein 2
, IAP homolog
, inhibitor of T-cell apoptosis protein
, inhibitor of apoptosis 1
, inhibitor of apoptosis protein
, apoptosis inhibitor 2
, baculoviral IAP repeat-containing 3