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Browse our anti-BIRC5 (BIRC5) Antibodies

Full name:
anti-Baculoviral IAP Repeat-Containing 5 Antibodies (BIRC5)
On www.antibodies-online.com are 83 Baculoviral IAP Repeat-Containing 5 (BIRC5) Antibodies from 19 different suppliers available. Additionally we are shipping BIRC5 Kits (17) and BIRC5 Proteins (14) and many more products for this protein. A total of 124 BIRC5 products are currently listed.
Synonyms:
AAC-11, AP14, Api4, EPR-1, survivin40, TIAP
list all antibodies Gene Name GeneID UniProt
BIRC5 332 O15392
BIRC5 11799 O70201
BIRC5 64041 Q9JHY7

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Top referenced anti-BIRC5 Antibodies

  1. Human Monoclonal BIRC5 Primary Antibody for WB - ABIN396525 : Niu, Cheng, Ren, Yang: Interaction of Beclin 1 with survivin regulates sensitivity of human glioma cells to TRAIL-induced apoptosis. in FEBS letters 2010 (PubMed)
    Show all 5 references for ABIN396525

  2. Human Polyclonal BIRC5 Primary Antibody for IHC (p) - ABIN181413 : Liggins, Orlicky, Bloomquist, Gianani: Developmentally regulated expression of Survivin in human pancreatic islets. in Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society 2004 (PubMed)
    Show all 2 references for ABIN181413

  3. Human Monoclonal BIRC5 Primary Antibody for IF, IP - ABIN559893 : Yamazaki, Fujiwara, Yukinaga, Ebisuya, Shiki, Kurihara, Kioka, Kambe, Nagao, Nishida, Masuda: The closely related RNA helicases, UAP56 and URH49, preferentially form distinct mRNA export machineries and coordinately regulate mitotic progression. in Molecular biology of the cell 2010 (PubMed)
    Show all 2 references for ABIN559893

  4. Human Polyclonal BIRC5 Primary Antibody for EIA, IF - ABIN500839 : Ambrosini, Adida, Altieri: A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma. in Nature medicine 1997 (PubMed)

  5. Human Polyclonal BIRC5 Primary Antibody for WB - ABIN374456 : Li, Ambrosini, Chu, Plescia, Tognin, Marchisio, Altieri: Control of apoptosis and mitotic spindle checkpoint by survivin. in Nature 1999 (PubMed)

  6. Mouse (Murine) Polyclonal BIRC5 Primary Antibody for WB - ABIN319040 : Verhagen, Coulson, Vaux: Inhibitor of apoptosis proteins and their relatives: IAPs and other BIRPs. in Genome biology 2001 (PubMed)

More Antibodies against BIRC5 Interaction Partners

Human Baculoviral IAP Repeat-Containing 5 (BIRC5) interaction partners

  1. we discovered a novel mechanism mediated by Smad4 (show SMAD4 Antibodies) to trigger 5-FU chemosensitivity through cell cycle arrest by inhibiting the PI3K (show PIK3CA Antibodies)/Akt (show AKT1 Antibodies)/CDC2 (show CDK1 Antibodies)/survivin cascade.

  2. It also inhibits the mRNA levels of Survivin gene.

  3. Overexpression of miR494 and silencing survivin RNA through the use of survivin shRNA inhibited the expression of survivin and attenuated PC3 (show PCSK1 Antibodies) cell growth in vitro and in vivo.

  4. Expression of livin (show BIRC7 Antibodies), survivin and caspase-3 (show CASP3 Antibodies) are closely related to the occurrence and development of prostatic cancer.

  5. Survivin is a key gene for regulating squamous cell carcinoma (SCC (show CYP11A1 Antibodies)) cancer stem cell formation and cancer SCC (show CYP11A1 Antibodies) development.

  6. results indicate that survivin functions as a common mediator of gemcitabine- and TRAIL-induced cell death.

  7. We defined Survivin as a constitutive actor of HR in breast cancers, and implies that its inhibition would enhance cell vulnerability upon PARP (show COL11A2 Antibodies) inhibition.

  8. Studies on survivin in NP cells may aid in increasing the understanding of the complex processes underlying NP cell degeneration, and could provide fundamental information for gene therapy to inhibit this degeneration in vitro

  9. Suggest that the p53 (show TP53 Antibodies)-p21 (show CDKN1A Antibodies)-DREAM-CDE/CHR pathway regulates p53 (show TP53 Antibodies)-dependent repression of Survivin, CDC25C (show CDC25C Antibodies), and PLK1 (show PLK1 Antibodies) in HCT116 cells.

  10. Overexpression of FOXM1 (show FOXM1 Antibodies), XIAP (show XIAP Antibodies), and Survivin contributes to the development of drug-resistance and is associated with poor clinical outcome in breast cancer patients.

Cow (Bovine) Baculoviral IAP Repeat-Containing 5 (BIRC5) interaction partners

  1. Survivin is important for optimal development of bovine blastocysts and confirm that survivin expression suppresses apoptosis of pre-implantation embryos.

Pig (Porcine) Baculoviral IAP Repeat-Containing 5 (BIRC5) interaction partners

  1. Dermatoplasty can decrease spermatogenic cells and reduce Survivin protein expression.

  2. Report survivin expression in the normal pancreas.

Mouse (Murine) Baculoviral IAP Repeat-Containing 5 (BIRC5) interaction partners

  1. Survivin is a key gene for regulating squamous cell carcinoma (SCC (show CYP11A1 Antibodies)) cancer stem cell formation and cancer SCC (show CYP11A1 Antibodies) development.

  2. In colorectal cancer mice with downregulated expression of survivin, there were higher numbers of apoptotic cells and decreased expression levels of bcl2 (show BCL2 Antibodies) and ki67 (show MKI67 Antibodies).

  3. survivin is essential for B cell division but does not affect survival of naive B cells. Survival of proliferating B cells may be impacted indirectly by survivin deficiency because of increased genotoxic stress caused by failed chromosomal segregation.

  4. Survivin directly participates in PRL (show PRL Antibodies)-mediated beta cell proliferation via Akt (show AKT1 Antibodies), STAT5 (show STAT5A Antibodies)-PIM (show PIM1 Antibodies) and ERK (show EPHB2 Antibodies) signalling pathways during pregnancy

  5. Studied competitive inhibition of survivin using a cell-permeable recombinant protein induces cancer-specific apoptosis in colon cancer model.

  6. Results suggest a role for survivin in regulating adult neural precursor activity and inhibiting apoptosis or programmed cell death in the dentate gyrus following brain injury

  7. NR4A1 (show NR4A1 Antibodies) protects pancreatic beta-cells against endoplasmic reticulum stress-mediated apoptosis by up-regulating Survivin expression and down-regulating CHOP (show DDIT3 Antibodies) expression.

  8. Studies indicate the importance of survivin in Sonic hedgehog (SHH (show SHH Antibodies))-driven medulloblastoma (MB).

  9. the Skp1 (show SKP1 Antibodies).Cul1 (show CUL1 Antibodies).F-box protein (show FBXO30 Antibodies) complex subunit Fbxl7 (show FBXL7 Antibodies) modulates mitochondrial function by controlling the cellular abundance of survivin

  10. Both HIF1-alpha (show HIF1A Antibodies) and survivin are involved in the retinal neovascularization in oxygen-induced retinopathy.

BIRC5 Antigen Profile

Antigen Summary

This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Alternative names and synonyms associated with BIRC5

  • baculoviral IAP repeat containing 5 (BIRC5) antibody
  • baculoviral IAP repeat-containing 5-like (LOC696283) antibody
  • baculoviral IAP repeat-containing 5 (Birc5) antibody
  • AAC-11 antibody
  • AP14 antibody
  • Api4 antibody
  • EPR-1 antibody
  • survivin40 antibody
  • TIAP antibody

Protein level used designations for BIRC5

baculoviral IAP repeat-containing 5 (survivin) , baculoviral IAP repeat-containing protein 5 , baculoviral IAP repeat-containing 5 (survivin)-like , apoptosis inhibitor survivin , baculoviral IAP repeat-containing 5 , apoptosis inhibitor 4 , survivin variant 3 alpha , survivin

GENE ID SPECIES
455276 Pan troglodytes
696283 Macaca mulatta
100172652 Pongo abelii
332 Homo sapiens
414925 Bos taurus
493835 Felis catus
397266 Sus scrofa
442936 Canis lupus familiaris
11799 Mus musculus
64041 Rattus norvegicus
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