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anti-Human BIRC5 Antibodies:
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Human Monoclonal BIRC5 Primary Antibody for WB - ABIN396525
Niu, Cheng, Ren, Yang: Interaction of Beclin 1 with survivin regulates sensitivity of human glioma cells to TRAIL-induced apoptosis. in FEBS letters 2010
Show all 5 references for ABIN396525
Human Polyclonal BIRC5 Primary Antibody for IHC (p) - ABIN181413
Liggins, Orlicky, Bloomquist, Gianani: Developmentally regulated expression of Survivin in human pancreatic islets. in Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society 2004
Show all 2 references for ABIN181413
Human Monoclonal BIRC5 Primary Antibody for IF, IP - ABIN559893
Yamazaki, Fujiwara, Yukinaga, Ebisuya, Shiki, Kurihara, Kioka, Kambe, Nagao, Nishida, Masuda: The closely related RNA helicases, UAP56 and URH49, preferentially form distinct mRNA export machineries and coordinately regulate mitotic progression. in Molecular biology of the cell 2010
Show all 2 references for ABIN559893
Human Polyclonal BIRC5 Primary Antibody for EIA, IF - ABIN500839
Ambrosini, Adida, Altieri: A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma. in Nature medicine 1997
Human Polyclonal BIRC5 Primary Antibody for WB - ABIN374456
Li, Ambrosini, Chu, Plescia, Tognin, Marchisio, Altieri: Control of apoptosis and mitotic spindle checkpoint by survivin. in Nature 1999
Mouse (Murine) Polyclonal BIRC5 Primary Antibody for WB - ABIN319040
Verhagen, Coulson, Vaux: Inhibitor of apoptosis proteins and their relatives: IAPs and other BIRPs. in Genome biology 2001
we discovered a novel mechanism mediated by Smad4 (show SMAD4 Antibodies) to trigger 5-FU chemosensitivity through cell cycle arrest by inhibiting the PI3K (show PIK3CA Antibodies)/Akt (show AKT1 Antibodies)/CDC2 (show CDK1 Antibodies)/survivin cascade.
It also inhibits the mRNA levels of Survivin gene.
Overexpression of miR494 and silencing survivin RNA through the use of survivin shRNA inhibited the expression of survivin and attenuated PC3 (show PCSK1 Antibodies) cell growth in vitro and in vivo.
Expression of livin (show BIRC7 Antibodies), survivin and caspase-3 (show CASP3 Antibodies) are closely related to the occurrence and development of prostatic cancer.
Survivin is a key gene for regulating squamous cell carcinoma (SCC (show CYP11A1 Antibodies)) cancer stem cell formation and cancer SCC (show CYP11A1 Antibodies) development.
results indicate that survivin functions as a common mediator of gemcitabine- and TRAIL-induced cell death.
We defined Survivin as a constitutive actor of HR in breast cancers, and implies that its inhibition would enhance cell vulnerability upon PARP (show COL11A2 Antibodies) inhibition.
Studies on survivin in NP cells may aid in increasing the understanding of the complex processes underlying NP cell degeneration, and could provide fundamental information for gene therapy to inhibit this degeneration in vitro
Suggest that the p53 (show TP53 Antibodies)-p21 (show CDKN1A Antibodies)-DREAM-CDE/CHR pathway regulates p53 (show TP53 Antibodies)-dependent repression of Survivin, CDC25C (show CDC25C Antibodies), and PLK1 (show PLK1 Antibodies) in HCT116 cells.
Overexpression of FOXM1 (show FOXM1 Antibodies), XIAP (show XIAP Antibodies), and Survivin contributes to the development of drug-resistance and is associated with poor clinical outcome in breast cancer patients.
Survivin is important for optimal development of bovine blastocysts and confirm that survivin expression suppresses apoptosis of pre-implantation embryos.
Dermatoplasty can decrease spermatogenic cells and reduce Survivin protein expression.
Report survivin expression in the normal pancreas.
In colorectal cancer mice with downregulated expression of survivin, there were higher numbers of apoptotic cells and decreased expression levels of bcl2 (show BCL2 Antibodies) and ki67 (show MKI67 Antibodies).
survivin is essential for B cell division but does not affect survival of naive B cells. Survival of proliferating B cells may be impacted indirectly by survivin deficiency because of increased genotoxic stress caused by failed chromosomal segregation.
Survivin directly participates in PRL (show PRL Antibodies)-mediated beta cell proliferation via Akt (show AKT1 Antibodies), STAT5 (show STAT5A Antibodies)-PIM (show PIM1 Antibodies) and ERK (show EPHB2 Antibodies) signalling pathways during pregnancy
Studied competitive inhibition of survivin using a cell-permeable recombinant protein induces cancer-specific apoptosis in colon cancer model.
Results suggest a role for survivin in regulating adult neural precursor activity and inhibiting apoptosis or programmed cell death in the dentate gyrus following brain injury
NR4A1 (show NR4A1 Antibodies) protects pancreatic beta-cells against endoplasmic reticulum stress-mediated apoptosis by up-regulating Survivin expression and down-regulating CHOP (show DDIT3 Antibodies) expression.
Studies indicate the importance of survivin in Sonic hedgehog (SHH (show SHH Antibodies))-driven medulloblastoma (MB).
the Skp1 (show SKP1 Antibodies).Cul1 (show CUL1 Antibodies).F-box protein (show FBXO30 Antibodies) complex subunit Fbxl7 (show FBXL7 Antibodies) modulates mitochondrial function by controlling the cellular abundance of survivin
Both HIF1-alpha (show HIF1A Antibodies) and survivin are involved in the retinal neovascularization in oxygen-induced retinopathy.
This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
baculoviral IAP repeat-containing 5 (survivin)
, baculoviral IAP repeat-containing protein 5
, baculoviral IAP repeat-containing 5 (survivin)-like
, apoptosis inhibitor survivin
, baculoviral IAP repeat-containing 5
, apoptosis inhibitor 4
, survivin variant 3 alpha