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anti-Human BIRC5 Antibodies:
anti-Mouse (Murine) BIRC5 Antibodies:
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Human Monoclonal BIRC5 Primary Antibody for WB - ABIN396525
Niu, Cheng, Ren, Yang: Interaction of Beclin 1 with survivin regulates sensitivity of human glioma cells to TRAIL-induced apoptosis. in FEBS letters 2010
Show all 5 references for ABIN396525
Human Polyclonal BIRC5 Primary Antibody for IHC (p) - ABIN181413
Liggins, Orlicky, Bloomquist, Gianani: Developmentally regulated expression of Survivin in human pancreatic islets. in Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society 2004
Show all 2 references for ABIN181413
Human Monoclonal BIRC5 Primary Antibody for IF, IP - ABIN559893
Yamazaki, Fujiwara, Yukinaga, Ebisuya, Shiki, Kurihara, Kioka, Kambe, Nagao, Nishida, Masuda: The closely related RNA helicases, UAP56 and URH49, preferentially form distinct mRNA export machineries and coordinately regulate mitotic progression. in Molecular biology of the cell 2010
Show all 2 references for ABIN559893
Human Polyclonal BIRC5 Primary Antibody for EIA, IF - ABIN500839
Ambrosini, Adida, Altieri: A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma. in Nature medicine 1997
Human Polyclonal BIRC5 Primary Antibody for WB - ABIN374456
Li, Ambrosini, Chu, Plescia, Tognin, Marchisio, Altieri: Control of apoptosis and mitotic spindle checkpoint by survivin. in Nature 1999
Mouse (Murine) Polyclonal BIRC5 Primary Antibody for WB - ABIN319040
Verhagen, Coulson, Vaux: Inhibitor of apoptosis proteins and their relatives: IAPs and other BIRPs. in Genome biology 2001
MiR (show MLXIP Antibodies)-335 and miR (show MLXIP Antibodies)-34a can also regulate GC cell growth, apoptosis, and invasion at least partly through survivin.
Reduced levels of survivin can sensitize tumor cells to apoptosis.
Inhibition of survivin by YM155 overcomes statin resistance in renal cancer cells.
Data show that knockdown of signal transducer and activator of transcription (show STAT1 Antibodies) (STAT3 (show STAT3 Antibodies))- significantly inhibited the mRNA and protein levels of survivin.
High survivin expression is associated with gastric cancer.
survivin may have a role in radioresistance of laryngeal squamous cell carcinoma
High survivin expression is associated with radioresistance in HER2 (show ERBB2 Antibodies)-positive breast cancers.
the blockade of survivin will allow for the treatment of glioblastoma, partially attributing to the inhibition of EGFR (show EGFR Antibodies) and MMP9 (show MMP9 Antibodies) expression.
Mi335 might function as a tumor suppressor in osteosarcoma(OS), and downregulation of miR (show MLXIP Antibodies)-335 in OS cells contributes to the decreased apoptotic potential of OS cells through derepression of survivin.
results suggest that high-grade glioma expressing high level of alpha5beta1 integrin may benefit from associated therapies including integrin antagonists and repressors of survivin expression.
Survivin is important for optimal development of bovine blastocysts and confirm that survivin expression suppresses apoptosis of pre-implantation embryos.
Dermatoplasty can decrease spermatogenic cells and reduce Survivin protein expression.
Report survivin expression in the normal pancreas.
Survivin is a key regulator of gut (show GUSB Antibodies) tissue integrity by regulating epithelial homeostasis in the stem cell niche.
TGFbetaRI inhibition in an injured adult heart could both stimulate the autocrine/paracrine activity of survivin and inhibit Wnt (show WNT2 Antibodies) in CPCs to mediate cardioprotection and improve cardiac function.
Survivin is a key gene for regulating squamous cell carcinoma (SCC (show CYP11A1 Antibodies)) cancer stem cell formation and cancer SCC (show CYP11A1 Antibodies) development.
In colorectal cancer mice with downregulated expression of survivin, there were higher numbers of apoptotic cells and decreased expression levels of bcl2 (show BCL2 Antibodies) and ki67 (show MKI67 Antibodies).
survivin is essential for B cell division but does not affect survival of naive B cells. Survival of proliferating B cells may be impacted indirectly by survivin deficiency because of increased genotoxic stress caused by failed chromosomal segregation.
Survivin directly participates in PRL (show PRL Antibodies)-mediated beta cell proliferation via Akt (show AKT1 Antibodies), STAT5 (show STAT5A Antibodies)-PIM (show PIM1 Antibodies) and ERK (show EPHB2 Antibodies) signalling pathways during pregnancy
Studied competitive inhibition of survivin using a cell-permeable recombinant protein induces cancer-specific apoptosis in colon cancer model.
Results suggest a role for survivin in regulating adult neural precursor activity and inhibiting apoptosis or programmed cell death in the dentate gyrus following brain injury
NR4A1 (show NR4A1 Antibodies) protects pancreatic beta-cells against endoplasmic reticulum stress-mediated apoptosis by up-regulating Survivin expression and down-regulating CHOP (show DDIT3 Antibodies) expression.
Studies indicate the importance of survivin in Sonic hedgehog (SHH (show SHH Antibodies))-driven medulloblastoma (MB).
This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
baculoviral IAP repeat-containing 5 (survivin)
, baculoviral IAP repeat-containing protein 5
, baculoviral IAP repeat-containing 5 (survivin)-like
, apoptosis inhibitor survivin
, baculoviral IAP repeat-containing 5
, apoptosis inhibitor 4
, survivin variant 3 alpha