Browse our anti-BIRC5 (BIRC5) Antibodies

Full name:
anti-Baculoviral IAP Repeat-Containing 5 Antibodies (BIRC5)
On are 85 Baculoviral IAP Repeat-Containing 5 (BIRC5) Antibodies from 19 different suppliers available. Additionally we are shipping BIRC5 Proteins (24) and BIRC5 Kits (13) and many more products for this protein. A total of 131 BIRC5 products are currently listed.
AAC-11, AP14, Api4, EPR-1, survivin40, TIAP
list all antibodies Gene Name GeneID UniProt
BIRC5 332 O15392
BIRC5 11799 O70201
BIRC5 64041 Q9JHY7

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anti-Human BIRC5 Antibodies:

anti-Mouse (Murine) BIRC5 Antibodies:

anti-Rat (Rattus) BIRC5 Antibodies:

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Top referenced anti-BIRC5 Antibodies

  1. Human Monoclonal BIRC5 Primary Antibody for WB - ABIN396525 : Niu, Cheng, Ren, Yang: Interaction of Beclin 1 with survivin regulates sensitivity of human glioma cells to TRAIL-induced apoptosis. in FEBS letters 2010 (PubMed)
    Show all 5 references for 396525

  2. Human Monoclonal BIRC5 Primary Antibody for FACS - ABIN4895256 : Mera, Magnusson, Tarkowski, Bokarewa: Extracellular survivin up-regulates adhesion molecules on the surface of leukocytes changing their reactivity pattern. in Journal of leukocyte biology 2007 (PubMed)
    Show all 3 references for 4895256

  3. Human Polyclonal BIRC5 Primary Antibody for IHC (p) - ABIN181413 : Liggins, Orlicky, Bloomquist, Gianani: Developmentally regulated expression of Survivin in human pancreatic islets. in Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society 2004 (PubMed)
    Show all 2 references for 181413

  4. Human Monoclonal BIRC5 Primary Antibody for FACS - ABIN4898957 : Schneider, Costa, Legrand, Bigot, Lecleire, Grassi, Vannier, Vasse: In vitro secretion of matrix metalloprotease 9 is a prognostic marker in childhood acute lymphoblastic leukemia. in Leukemia research 2010 (PubMed)

  5. Human Monoclonal BIRC5 Primary Antibody for FACS - ABIN4895255 : Perabo, Frössler, Landwehrs, Schmidt, von Rücker, Wirger, Müller: Indirubin-3'-monoxime, a CDK inhibitor induces growth inhibition and apoptosis-independent up-regulation of survivin in transitional cell cancer. in Anticancer research 2006 (PubMed)

  6. Mouse (Murine) Polyclonal BIRC5 Primary Antibody for WB - ABIN319040 : Verhagen, Coulson, Vaux: Inhibitor of apoptosis proteins and their relatives: IAPs and other BIRPs. in Genome biology 2001 (PubMed)

  7. Human Polyclonal BIRC5 Primary Antibody for EIA, IF - ABIN401046 : Ambrosini, Adida, Altieri: A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma. in Nature medicine 1997 (PubMed)

More Antibodies against BIRC5 Interaction Partners

Human Baculoviral IAP Repeat-Containing 5 (BIRC5) interaction partners

  1. This study shows that both survivin and TIIalpha are independent prognostic predictors in human grade II/III astrocytomas stratified for IDH1 (show IDH1 Antibodies)-mutation status

  2. this study shows that c-IAP-2 (show BIRC3 Antibodies) may prevent HIV-viral protein -mediated mitochondrial depolarization through stabilizing TRAF-1 (show TRAF1 Antibodies)/2 expression and sequential inhibition of caspase-8 (show CASP8 Antibodies), Bid (show BID Antibodies), and Bax (show BAX Antibodies)

  3. the N-terminus of survivin is a mitochondrial-targeting sequence that regulates Src (show SRC Antibodies).

  4. Reciprocal regulation of BMF (show BMF Antibodies) and BIRC5 is linked to Eomes (show EOMES Antibodies) overexpression in colorectal cancer.

  5. A higher survivin expression seems to represent an unfavorable and robust prognostic factor for clinical outcomes in renal cell carcinoma (show MOK Antibodies) patients [review; meta-analysis].

  6. Aurora-C (show AURKC Antibodies) interactions with members of the Chromosome Passenger Complex (CPC), Survivin and Inner Centromere Protein (INCENP (show INCENP Antibodies)) in reference to known Aurora-B (show AURKB Antibodies) interactions to understand the functional significance of Aurora-C (show AURKC Antibodies) overexpression in human cancer cells, is reported.

  7. study revealed a critical role of miR (show MLXIP Antibodies)-138- 5p as a tumor suppressive miRNA in bladder carcinogenesis, explored the molecular mechanisms by which aberrant miR (show MLXIP Antibodies)-138-5p expression contributes to bladder cancer progression and identified Survivin as a direct target of miR (show MLXIP Antibodies)- 138-5p. Regulation of Survivin by miR (show MLXIP Antibodies)-138-5p might explain why the decrease of miR (show MLXIP Antibodies)-138-5p during bladder carcinogenesis can promote cancer progression.

  8. the overexpression of miR (show MLXIP Antibodies)-141 augments anoikis resistance in ovarian cancer cells by targeting and repressing the expression of KLF12 (show KLF12 Antibodies), which, in turn, competes for binding sites in the survivin promoter with Sp1 (show PSG1 Antibodies). The subsequent increase in survivin then protects ovarian cancer cells against anoikis by blocking the intrinsic apoptotic activity.

  9. we uncovered that folate deficiency could profoundly downregulate two prominent anti-apoptotic effectors including survivin and glucose-regulated protein-78 (show HSPA5 Antibodies). Silencing of either survivin or glucose-regulated protein-78 (show HSPA5 Antibodies) via small interfering RNA interfering technique established that both effectors could serve as reactive oxygen species sinker proteins

  10. The results indicate that CXCL12 (show CXCL12 Antibodies)/CXCR4 (show CXCR4 Antibodies) protects colorectal cancer cells against radiotherapy via survivin, implying an important underlying mechanism of resistance to radiotherapy during colorectal cancer therapy.

Cow (Bovine) Baculoviral IAP Repeat-Containing 5 (BIRC5) interaction partners

  1. Survivin is important for optimal development of bovine blastocysts and confirm that survivin expression suppresses apoptosis of pre-implantation embryos.

Pig (Porcine) Baculoviral IAP Repeat-Containing 5 (BIRC5) interaction partners

  1. Dermatoplasty can decrease spermatogenic cells and reduce Survivin protein expression.

  2. Report survivin expression in the normal pancreas.

Mouse (Murine) Baculoviral IAP Repeat-Containing 5 (BIRC5) interaction partners

  1. this study shows that that sorafenib promotes the survival of bone marrow cells by up-regulating survivin

  2. Survivin was regulated by TGF-beta (show TGFB1 Antibodies) and was found to be highly expressed during mucosal healing following intestinal inflammation

  3. Survivin is a key regulator of gut (show GUSB Antibodies) tissue integrity by regulating epithelial homeostasis in the stem cell niche.

  4. TGFbetaRI inhibition in an injured adult heart could both stimulate the autocrine/paracrine activity of survivin and inhibit Wnt (show WNT2 Antibodies) in CPCs to mediate cardioprotection and improve cardiac function.

  5. Survivin is a key gene for regulating squamous cell carcinoma (SCC (show CYP11A1 Antibodies)) cancer stem cell formation and cancer SCC (show CYP11A1 Antibodies) development.

  6. In colorectal cancer mice with downregulated expression of survivin, there were higher numbers of apoptotic cells and decreased expression levels of bcl2 (show BCL2 Antibodies) and ki67 (show MKI67 Antibodies).

  7. survivin is essential for B cell division but does not affect survival of naive B cells. Survival of proliferating B cells may be impacted indirectly by survivin deficiency because of increased genotoxic stress caused by failed chromosomal segregation.

  8. Survivin directly participates in PRL (show PRL Antibodies)-mediated beta cell proliferation via Akt (show AKT1 Antibodies), STAT5 (show STAT5A Antibodies)-PIM (show PIM1 Antibodies) and ERK (show EPHB2 Antibodies) signalling pathways during pregnancy

  9. Studied competitive inhibition of survivin using a cell-permeable recombinant protein induces cancer-specific apoptosis in colon cancer model.

  10. Results suggest a role for survivin in regulating adult neural precursor activity and inhibiting apoptosis or programmed cell death in the dentate gyrus following brain injury

BIRC5 Antigen Profile

Antigen Summary

This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Alternative names and synonyms associated with BIRC5

  • baculoviral IAP repeat containing 5 (BIRC5) antibody
  • baculoviral IAP repeat-containing 5-like (LOC696283) antibody
  • baculoviral IAP repeat-containing 5 (Birc5) antibody
  • AAC-11 antibody
  • AP14 antibody
  • Api4 antibody
  • EPR-1 antibody
  • survivin40 antibody
  • TIAP antibody

Protein level used designations for BIRC5

baculoviral IAP repeat-containing 5 (survivin) , baculoviral IAP repeat-containing protein 5 , baculoviral IAP repeat-containing 5 (survivin)-like , apoptosis inhibitor survivin , baculoviral IAP repeat-containing 5 , apoptosis inhibitor 4 , survivin variant 3 alpha , survivin

455276 Pan troglodytes
696283 Macaca mulatta
100172652 Pongo abelii
332 Homo sapiens
414925 Bos taurus
493835 Felis catus
397266 Sus scrofa
442936 Canis lupus familiaris
11799 Mus musculus
64041 Rattus norvegicus
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