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anti-Human EPR1 Antibodies:
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Survivin (show BIRC5 Antibodies) expression in lung squamous cell carcinoma was increased compared to normal tissue, and was unaffected by methylation status of the surviving gene.
Survivin (show BIRC5 Antibodies) gene promoter methylation was more frequent in gastric cancer patients than in controls.
These findings uncover the significance of Merlin (show NF2 Antibodies) protein expression and Survivin (show BIRC5 Antibodies) labeling index as prognosticators for poor clinical outcome in two independent Malignant pleural mesothelioma cohorts.
circulating Survivin (show BIRC5 Antibodies) in prostate cancer patients was higher compared to controls, with the highest levels in African-American (AA) patients. AA patients with prostate cancer contained higher amounts of extracellular vesicles (EVs) in their plasma and sera than European-American (EA) patients. EVs from AA patients with prostate cancer contained higher amounts of Survivin (show BIRC5 Antibodies), XIAP (show XIAP Antibodies) and cIAP-2 (show BIRC3 Antibodies) than EVs from EA patients.
results indicate that survivin (show BIRC5 Antibodies) is of prognostic signi fi cance in patients with renal cell carcinoma (show MOK Antibodies)
The aim of this study was to compare the prognostic value of the histopathological grading and the conventional biomarker MIB-1 with expression of the anti-apoptotic protein survivin (show BIRC5 Antibodies) to see if this biomarker could complement recurrence prediction.
Data suggest that the first 22 bp of exon 3 in BIRC5 (show BIRC5 Antibodies) contain cis (show CISH Antibodies)-acting elements that enhance the exclusion of exon 3 to generate the survivin (show BIRC5 Antibodies) DEx3 mRNA isoform via exclusion/deletion of exon 3; Sam68 (show KHDRBS1 Antibodies) is a possible trans-acting factor that binds to this cis (show CISH Antibodies)-acting element and regulates exon 3 splicing. (BIRC5/survivin (show BIRC5 Antibodies) = baculoviral IAP repeat containing 5 (show BIRC5 Antibodies); Sam68 (show KHDRBS1 Antibodies) = GAP-associated tyrosine phosphoprotein p62 (show KHDRBS1 Antibodies))
our data suggest the existence of a novel pre-metastatic phase quiescent-breast cancer stem cells (Q-BCSCs) before epithelial to mesenchymal transition and SURVIVIN (show BIRC5 Antibodies) acts as a marker for Quiescent-BCSCs
Expressions of SDF-1 (show CXCL12 Antibodies), survivin (show BIRC5 Antibodies) and smac (show DIABLO Antibodies) were significantly higher in epithelial ovarian cancer tissue than those in normal tissue.
Survivin (show BIRC5 Antibodies) expression predicted disease-free survival in high grade papillary urothelial carcinomas.
This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
apoptosis inhibitor 4
, apoptosis inhibitor survivin
, baculoviral IAP repeat-containing protein 5
, survivin variant 3 alpha