Browse our ATG12 Proteins (ATG12)

Full name:
Autophagy Related 12 Proteins (ATG12)
On are 18 Autophagy Related 12 (ATG12) Proteins from 4 different suppliers available. Additionally we are shipping ATG12 Antibodies (208) and ATG12 Kits (15) and many more products for this protein. A total of 253 ATG12 products are currently listed.
4931423H11Rik, A330058M13Rik, AO090001000593, apg12, Apg12l, ATG12, Atg12l, AUTOPHAGY 12, AUTOPHAGY 12 B, CG10861, DDBDRAFT_0185323, DDBDRAFT_0191412, DDB_0185323, DDB_0191412, Dmel\\CG10861, FBR93, HAPG12
list all proteins Gene Name GeneID UniProt
ATG12 9140 O94817
ATG12 361321 Q2TBJ5
ATG12 67526 Q9CQY1

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ATG12 Proteins (ATG12) by Origin

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Human Autophagy Related 12 (ATG12) interaction partners

  1. ATG5-ATG12 is increased in hepatitis B virus-associated hepatocellular carcinoma and has a role in apoptosis

  2. Analysis of hepatitis B virus capsid maturation steps revealed that Rab33B and Atg5/12/16L1 are required for proper particle assembly and/or stability.

  3. reveal a novel interconnection between autophagy, proteasome activity, and cell death mediated by the ubiquitin-like properties of ATG12

  4. The results revealed that the expression of Atg12 and LC3 (show MAP1LC3A Proteins) II/LC3 (show MAP1LC3A Proteins) I in the chondrocytes treated with TXC increased, compared to that in the untreated chondrocytes

  5. Cav-1 competitively interacts with the ATG12-ATG5 system to suppress the formation and function of the latter in lung epithelial cells.

  6. ATG12 is a novel determinant of breast cancer primary resistance to HER1 (show EGFR Proteins)/2-targeted therapeutics.

  7. study to identify role of conjugation between ATG12 and ATG5 in LC3 lipidation; structural and mutational analyses of ATG12~ATG5-ATG16N revealed the conjugation generates a patch across ATG12 and ATG5 required for E3 activity

  8. These data relate LC3B, ATG5 and ATG12 to mitochondrial quality control after oxidative damage, and to cellular longevity.

  9. The Atg12 is as a positive mediator of mitochondrial apoptosis and show that Atg12 directly regulates the apoptotic pathway by binding and inactivating prosurvival Bcl-2 (show BCL2 Proteins) family members, including Bcl-2 (show BCL2 Proteins) and Mcl-1 (show MCL1 Proteins).

  10. Calpain1 plays an important role in controlling the levels of autophagy in normal living cells by regulating the levels of a key signaling molecule, ATG12-ATG5 conjugate.

Mouse (Murine) Autophagy Related 12 (ATG12) interaction partners

  1. miR-30b inhibited autophagy to alleviate hepatic ischemia-reperfusion injury by decreasing the Atg12-Atg5 conjugate.

  2. Although genetic deletion of either Atg12 or Atg5 (show ATG5 Proteins) renders POMC (show POMC Proteins) neurons autophagy-deficient, mice lacking Atg5 (show ATG5 Proteins) in POMC (show POMC Proteins) neurons do not exhibit these phenotypes.

  3. ATG12-ATG3 (show ATG3 Proteins) interacts with Alix (show PDCD6IP Proteins) to promote basal autophagic flux and late endosome function.

  4. Atg5 (show ATG5 Proteins)-Atg12/Atg16L1 (show ATG16L1 Proteins) protein complex is required for IFNgamma-mediated host defense against murine norovirus infection.

  5. Vaccinia virus actively disrupts the cellular autophagy through a novel molecular mechanism that is associated with aberrant LC3 (show MAP1LC3A Proteins) lipidation and a direct conjugation between ATG12 and ATG3 (show ATG3 Proteins).

  6. Despite forming the Atg12-Atg5-Atg16L2 complex, Atg16L2 is not recruited to phagophores and is mostly present in the cytosol.

  7. Autophagy participated the process of immune response of anti-MTB (show NCAPG2 Proteins). Atg12 were the important molecule which control the formation of autophagy when MTB (show NCAPG2 Proteins) infected.

  8. Overexpression of Atg5 or Atg12 resulted in Atg5-Atg12 conjugate formation and suppression of RNA-mediated signaling.

ATG12 Protein Profile

Protein Summary

Autophagy is a process of bulk protein degradation in which cytoplasmic components, including organelles, are enclosed in double-membrane structures called autophagosomes and delivered to lysosomes or vacuoles for degradation. ATG12 is the human homolog of a yeast protein involved in autophagy (Mizushima et al., 1998

Alternative names and synonyms associated with ATG12

  • autophagy related 12 (ATG12)
  • autophagy related 12 (Atg12)
  • ubiquitin-like protein ATG12B (APG12B)
  • Atg12p (ATG12)
  • autophagy protein (APG12)
  • APG12/APG12B (ARALYDRAFT_318184)
  • autophagy associated protein Atg12 (apg12)
  • Autophagy-specific gene 12 (Atg12)
  • ATG12 autophagy related 12 homolog (S. cerevisiae) (atg12)
  • ATG12 autophagy related 12 homolog (S. cerevisiae) (ATG12)
  • autophagy associated ubiquitin-like modifier Atg12 (atg12)
  • similar to S. cerevisiae ATG12 (YBR217W) which nucleates preautophagosome formation as a conjugate with Atg5 (ATG12)
  • Autophagy-related protein 12 (Autophagy-related ubiquitin-like modifier ATG12) (ATG12)
  • autophagy protein 12 (atg12)
  • autophagy related 12 (atg12)
  • autophagy-related protein 12 (ANI_1_922094)
  • autophagy-related protein 12 (AOR_1_1064164)
  • 4931423H11Rik protein
  • A330058M13Rik protein
  • AO090001000593 protein
  • apg12 protein
  • Apg12l protein
  • ATG12 protein
  • Atg12l protein
  • AUTOPHAGY 12 protein
  • AUTOPHAGY 12 B protein
  • CG10861 protein
  • DDBDRAFT_0185323 protein
  • DDBDRAFT_0191412 protein
  • DDB_0185323 protein
  • DDB_0191412 protein
  • Dmel\\CG10861 protein
  • FBR93 protein
  • HAPG12 protein

Protein level used designations for Autophagy Related 12 Proteins (ATG12)

ATG12 autophagy related 12 homolog , Apg12 (autophagy, yeast) homolog , ubiquitin-like protein ATG12 , autophagy-related 12 , autophagy-related protein 12 , autophagy protein , APG12/APG12B , autophagy associated protein Atg12 , Autophagy-related protein 12 , Atg12-PB , CG10861-PB , ATG12 autophagy related 12 homolog (S. cerevisiae) , potential preautophagosome nucleating protein Atg12 , Autophagy-related protein 12 (Autophagy-related ubiquitin-like modifier ATG12)

9140 Homo sapiens
361321 Rattus norvegicus
820611 Arabidopsis thaliana
852518 Saccharomyces cerevisiae S288c
5728356 Chlamydomonas reinhardtii
9321066 Arabidopsis lyrata subsp. lyrata
9526724 Arthroderma benhamiae CBS 112371
100173230 Pongo abelii
39383 Drosophila melanogaster
427390 Gallus gallus
474636 Canis lupus familiaris
570965 Danio rerio
743425 Pan troglodytes
767903 Bos taurus
2542368 Schizosaccharomyces pombe 972h-
3636046 Candida albicans SC5314
3636186 Candida albicans SC5314
4851930 Scheffersomyces stipitis CBS 6054
8623887 Dictyostelium discoideum AX4
100126654 Xenopus laevis
67526 Mus musculus
4984916 Aspergillus niger CBS 513.88
5991072 Aspergillus oryzae RIB40
100462745 Sus scrofa
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