Browse our anti-Beclin 1 (BECN1) Antibodies

Full name:
anti-Beclin 1, Autophagy Related Antibodies (BECN1)
On are 438 Beclin 1, Autophagy Related (BECN1) Antibodies from 29 different suppliers available. Additionally we are shipping Beclin 1 Kits (45) and Beclin 1 Proteins (19) and many more products for this protein. A total of 524 Beclin 1 products are currently listed.
4921513J16Rik, 5430417M23Rik, Atg6, Beclin-1, beclin1, becn1, VPS30, zgc:73097
list all antibodies Gene Name GeneID UniProt
BECN1 8678 Q14457
BECN1 56208 O88597
BECN1 114558 Q91XJ1

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anti-Human Beclin 1 Antibodies:

anti-Mouse (Murine) Beclin 1 Antibodies:

anti-Rat (Rattus) Beclin 1 Antibodies:

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Top referenced anti-Beclin 1 Antibodies

  1. Dog (Canine) Polyclonal Beclin 1 Primary Antibody for ICC, IF - ABIN259945 : Liang, Kleeman, Jiang, Gordon, Goldman, Berry, Herman, Levine: Protection against fatal Sindbis virus encephalitis by beclin, a novel Bcl-2-interacting protein. in Journal of virology 1998 (PubMed)
    Show all 31 references for 259945

  2. Human Monoclonal Beclin 1 Primary Antibody for IHC, IHC (p) - ABIN314194 : Ko, Lin, Flomenberg, Pestell, Howell, Sotgia, Lisanti, Martinez-Outschoorn: Glutamine fuels a vicious cycle of autophagy in the tumor stroma and oxidative mitochondrial metabolism in epithelial cancer cells: implications for preventing chemotherapy resistance. in Cancer biology & therapy 2012 (PubMed)
    Show all 16 references for 314194

  3. Human Polyclonal Beclin 1 Primary Antibody for IHC (p), WB - ABIN388545 : Baehrecke: Autophagy: dual roles in life and death? in Nature reviews. Molecular cell biology 2005 (PubMed)
    Show all 10 references for 388545

  4. Human Polyclonal Beclin 1 Primary Antibody for FACS, IHC (p) - ABIN388546 : Lum, DeBerardinis, Thompson: Autophagy in metazoans: cell survival in the land of plenty. in Nature reviews. Molecular cell biology 2005 (PubMed)
    Show all 10 references for 388546

  5. Human Monoclonal Beclin 1 Primary Antibody for IF, IHC (p) - ABIN387797 : Metzger, Saukko, Van Che, Tong, Puder, Riess, Nguyen: Age at onset in Huntington's disease is modified by the autophagy pathway: implication of the V471A polymorphism in Atg7. in Human genetics 2010 (PubMed)
    Show all 9 references for 387797

  6. Human Polyclonal Beclin 1 Primary Antibody for IF (cc), IF (p) - ABIN675384 : Tang, Li, Wei, Zhang, Chiu, Hasenmayer, Zhang, Zhang: Resveratrol-induced apoptosis is enhanced by inhibition of autophagy in esophageal squamous cell carcinoma. in Cancer letters 2013 (PubMed)
    Show all 8 references for 675384

  7. Human Monoclonal Beclin 1 Primary Antibody for EIA, IHC (p) - ABIN1449374 : Starr, Child, Wehrly, Hansen, Hwang, López-Otin, Virgin, Celli: Selective subversion of autophagy complexes facilitates completion of the Brucella intracellular cycle. in Cell host & microbe 2012 (PubMed)
    Show all 2 references for 1449374

  8. Chicken Monoclonal Beclin 1 Primary Antibody for IHC (p), IHC - ABIN314193 : Botbol, Patel, Macian: Common γ-chain cytokine signaling is required for macroautophagy induction during CD4+ T-cell activation. in Autophagy 2015 (PubMed)
    Show all 2 references for 314193

  9. Human Polyclonal Beclin 1 Primary Antibody for WB - ABIN658010 : Oberstein, Jeffrey, Shi: Crystal structure of the Bcl-XL-Beclin 1 peptide complex: Beclin 1 is a novel BH3-only protein. in The Journal of biological chemistry 2007 (PubMed)

  10. Chicken Monoclonal Beclin 1 Primary Antibody for IHC, WB - ABIN314196 : Sun, Li, Zhang, Chen, Zhang, Li, Deng, Qian, Jiao, Ji, Li, Wu, Yu, Feng, Zhu: Acetylation of Beclin 1 inhibits autophagosome maturation and promotes tumour growth. in Nature communications 2015 (PubMed)

More Antibodies against Beclin 1 Interaction Partners

Zebrafish Beclin 1, Autophagy Related (BECN1) interaction partners

  1. Beclin1 plays an important role in vincristine-induced dopaminergic neurons toxicity.

Human Beclin 1, Autophagy Related (BECN1) interaction partners

  1. Data suggest that BECN1 exhibits a helical region that transitions between packing (folding/unfolding) as part of either one of two conserved domains; packing of this helical region appears to have important implications for relative stability of autophagy-inactive and autophagy-active BECN1 complexes.

  2. downregulation of HOXC9 (show HOXC9 Antibodies) releases its transcriptional inhibition of DAPK1 (show DAPK1 Antibodies), resulting in the activation of the DAPK1 (show DAPK1 Antibodies)-Beclin1 pathway, which induces autophagy in glioblastoma cells

  3. ASPP2 (show TP53BP2 Antibodies) is a key regulator of BECN1-dependent autophagy.

  4. the polyQ domain enables wild-type ataxin 3 (show ATXN3 Antibodies) to interact with beclin 1, a key initiator of autophagy; this interaction allows the deubiquitinase activity of ataxin 3 (show ATXN3 Antibodies) to protect beclin 1 from proteasome-mediated degradation and thereby enables autophagy

  5. findings suggest that expression of cFLIPL regulates the basal interaction of Bcl-2 (show BCL2 Antibodies) with Beclin-1 and substantiates p53 (show TP53 Antibodies) dependent ubiquitination of Beclin-1 during autophagic stress to determine the fate of cell death or survival.

  6. Here, sequence analyses, structural modeling, mutagenesis combined with pull-down assays, X-ray crystal structure determination and small-angle X-ray scattering were used to investigate the Beclin 1-GAPR-1 interaction. changes in the structure of the equatorial groove combined with the improved dimerization of pentad mutant GAPR-1 are likely to abrogate binding to Beclin 1.

  7. Acetylated PGK1 (show PGK1 Antibodies) binds to and phosphorylates Beclin1 at S30 (show FAU Antibodies), leading to activation of the VPS34 (show PIK3C3 Antibodies)-Beclin1 complex to initiate autophagosomal formation.

  8. reactive oxygen species (ROS (show ROS1 Antibodies)) production was induced, which increased RelA (show NFkBP65 Antibodies) transcriptional activity and beclin 1 (BECN1) expression in oral cancer cells irradiated with LPL (show LCP1 Antibodies)

  9. Further data showed that reactive oxygen species-c-Jun (show JUN Antibodies) activation by HBx resulted in the release of beclin-1 from its association with beclin-2 to form a complex with VPS34 (show PIK3C3 Antibodies), thus enhancing autophagosome formation.

  10. Beclin1 interacts with both the N- and C-termini of LAPTM4B. Beclin1 competes with EGFR for LAPTM4B binding.

Mouse (Murine) Beclin 1, Autophagy Related (BECN1) interaction partners

  1. Genetically disrupting BECN1-BCL2 (show BCL2 Antibodies) binding hyperactivates autophagy in vivo, which sequestrates amyloid oligomers and prevents Alzheimer's disease progression.

  2. Data show that 1-month of oral treatment with beta-asarone reduces AChE, Abeta42, APP (show APP Antibodies) and Beclin-1 levels and alleviates some behavioral impairments by inhibiting the autophagy via regulating the PI3K/Akt (show AKT1 Antibodies)/mTOR (show FRAP1 Antibodies) pathway in APP (show APP Antibodies)/PS1 (show PSEN1 Antibodies) transgenic mice. The results further support the exploration of beta-asarone as a possible disease-modifying agent for the treatment of Alzheimer's disease.

  3. identify FAK (show PTK2 Antibodies) as a novel negative regulator of Beclin1-mediated autophagy and indicate that this pathway can facilitate the promotion of compensatory hypertrophic growth

  4. The results not only demonstrate that BECN1 as a PI3K-III component is essential for cytokinesis, but also suggest that BECN1 is not associated with autophagy pathway in mouse oocytes.

  5. this study shows that knockdown of beclin1 enhances macrophage-associated (show CD163 Antibodies) phagocytosis and intracellular killing of Pseudomonas aeruginosa

  6. provide the novel evidence that GADD45A (show GADD45A Antibodies) inhibits autophagy via impairing the BECN1-PIK3C3 (show PIK3C3 Antibodies) complex formation

  7. in-vitro genetic depletion of beclin-1 in high glucose treated adult rat cardiomyocytes markedly inhibited the level of autophagy and subsequent apoptotic cell death.

  8. suggest that neuronal death induced by decreased beclin 1 levels may also be due to impaired trophic factor signaling

  9. FBG1 (show FBXO2 Antibodies) degrades A1AT (show SERPINA1 Antibodies)-Z through a Beclin1-dependent arm of autophagy.

  10. Beclin 1 is required for neuron viability and regulates endosome pathways via the UVRAG (show UVRAG Antibodies)-VPS34 (show PIK3C3 Antibodies) complex.

Pig (Porcine) Beclin 1, Autophagy Related (BECN1) interaction partners

  1. Data indicate that the expression of MAP1LC3A (show MAP1LC3A Antibodies), B and autophagy-associated genes (ATG5 (show ATG5 Antibodies), mTOR (show FRAP1 Antibodies), Beclin-1) was increased in normal pigs, while decreased in miniature pigs.

Beclin 1 (BECN1) Antigen Profile

Antigen Summary

Beclin-1 participates in the regulation of autophagy and has an important role in development, tumorigenesis, and neurodegeneration (Zhong et al., 2009

Alternative names and synonyms associated with Beclin 1 (BECN1)

  • beclin 1, autophagy related (BECN1) antibody
  • beclin 1, autophagy related (becn1) antibody
  • beclin 1 (atg6) antibody
  • beclin 1 protein (atg6) antibody
  • beclin-1 (CpipJ_CPIJ011087) antibody
  • beclin-1 (PTRG_07825) antibody
  • beclin-1 (SJAG_01876) antibody
  • Beclin-1 (becn1) antibody
  • beclin 1 (coiled-coil, myosin-like BCL2 interacting protein) (becn1) antibody
  • beclin 1, autophagy related (Becn1) antibody
  • beclin-1-like (LOC100352353) antibody
  • 4921513J16Rik antibody
  • 5430417M23Rik antibody
  • Atg6 antibody
  • Beclin-1 antibody
  • beclin1 antibody
  • becn1 antibody
  • VPS30 antibody
  • zgc:73097 antibody

Protein level used designations for BECN1

beclin 1 (coiled-coil, myosin-like BCL2 interacting protein) , beclin-1 , beclin 1 , GRMZM2G092112 , beclin 1 proteinBeclin-1-like protein , Beclin-1 , myosin-like BCL2 interacting protein , ATG6 autophagy related 6 homolog , beclin 1 (coiled-coil, moesin-like BCL2 interacting protein) , beclin 1 (coiled-coil, moesin-like BCL2-interacting protein) , coiled-coil myosin-like BCL2-interacting protein , Bcl-2-interacting protein beclin , coiled-coil, myosin-like BCL2-interacting protein , beclin 1 (coiled-coil, myosin-like BCL2-interacting protein) , autophagy-related protein 6

454700 Pan troglodytes
619357 Xenopus (Silurana) tropicalis
653027 Takifugu rubripes
711649 Macaca mulatta
732797 Zea mays
6043853 Culex quinquefasciatus
6346099 Pyrenophora tritici-repentis Pt-1C-BFP
7048057 Schizosaccharomyces japonicus yFS275
100049387 Oryzias latipes
100136134 Oncorhynchus mykiss
100173145 Pongo abelii
100194789 Salmo salar
393846 Danio rerio
8678 Homo sapiens
56208 Mus musculus
444178 Xenopus laevis
420018 Gallus gallus
733576 Sus scrofa
527278 Bos taurus
114558 Rattus norvegicus
480513 Canis lupus familiaris
100721231 Cavia porcellus
100913170 Ovis aries
100352353 Oryctolagus cuniculus
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