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Human alpha Fetoprotein Protein expressed in Human - ABIN934756
Lee, Nguyen, Sim: A nanoplasmonic biosensor for label-free multiplex detection of cancer biomarkers. in Biosensors & bioelectronics 2015
Show all 2 Pubmed References
Human alpha Fetoprotein Protein expressed in Human - ABIN377076
Jee, Ang, Cha, Ang, Ling, Lim, Lee: Combinatorial bead-based peptide libraries improved for rapid and robust screenings. in Combinatorial chemistry & high throughput screening 2014
Human alpha Fetoprotein Protein expressed in Human - ABIN934454
Lee, Lee: Regression of hepatocarcinoma cells using RNA aptamer specific to alpha-fetoprotein. in Biochemical and biophysical research communications 2012
Human alpha Fetoprotein Protein expressed in Cell culture - ABIN573558
Mikhaylova, Schumacher, Borutzki, Neumann, Macharadze, El-Mousleh, Wahle, Zenclussen, Kreutz: Analysis of Y-P30/Dermcidin expression and properties of the Y-P30 peptide. in BMC research notes 2014
endogenous AFP expression in the perinatal liver is reduced in the absence of beta-catenin (show CTNNB1 Proteins), suggesting that beta-catenin (show CTNNB1 Proteins) regulates AFP during liver development.
Findings indicate that AFP expressed under experimental cryptorchid conditions plays a role as a regulatory factor in spermatogenesis and in hepatic generation.
AFP mRNA and VEGF-C (show VEGFC Proteins) mRNA in peripheral blood were significantly correlated with recurrence and metastasis of hepatocellular carcinoma.
A DEHP treatment-induced phenotype was identified with lack of glycogen (show GYS1 Proteins) accumula-tion and intracytoplasmic localization of beta-catenin (show CTNNB1 Proteins) which was associated with increased AFP gene expression.
The deficits observed in parental behavior of AFP knockout females could not be explained by any changes in olfactory function, novelty recognition or anxiety
Foxa1 (show FOXA1 Proteins) acts as a pioneer transcription factor in de novo activation of Afp, by exploiting a lack of methylation at juxtaposed transposed elements
The level of AFP mRNA in peripheral blood may indicate recurrence and/or metastasis after curative resection of hepatocellular carcinoma.
AFP affects cell proliferation by binding its receptor to trigger the signal transduction pathway of cAMP-PKA and alter the expression of K- ras (show HRAS Proteins) p21 genes
A murine Nkx2.8 (show NKX2-6 Proteins) was isolated from the Hepal-6 cell line and showed oligonucleotide binding competitive with fetoprotein transcription factor (show NR5A2 Proteins).
The mouse alpha-fetoprotein promoter is repressed in HepG2 hepatoma cells by hepatocyte nuclear factor-3 (show FOXA1 Proteins)
Irregular MIP (show TNPO1 Proteins) pattern by CEUS and high level of serum AFP-L3 were independent risk factors for poor outcome after successful RFA (show RPA1 Proteins). The Patients with these findings should be considered as special high-risk group in early-stage HCC (show FAM126A Proteins).
our data suggest that HBeAg seroconversion and liver cirrhosis are associated with the occurrence of HCC (show FAM126A Proteins) and that a surveillance system with regular measurement of AFP to watch for the occurrence of HCC (show FAM126A Proteins) may be mandatory for children and young patients with chronic HBV infection.
We could demonstrate in our cohort the superior detection of early stage HCC (show FAM126A Proteins) with the combined use of the respective biomarkers and in particular GALAD even in AFP-negative tumors.
A correlation was found between serum AFP concentration and age in extremely low-birthweight infants (ELBWI), and the 95%CI of serum AFP concentration was determined for ELBWI up to 2 years after birth.
rAFP promoted growth of the human HCC (show FAM126A Proteins) cells, antagonize paclitaxel inhibition of HCC (show FAM126A Proteins) cell proliferation, suppress expression of active caspase-3 (show CASP3 Proteins), and promote expression of Ras and survivin (show BIRC5 Proteins).
Measurements of serum alpha-fetoprotein (AFP) levels could be helpful in detecting progression or recurrence in treated patients with hepatitis B virus (HBV) - hepatocellular carcinoma (HCC (show FAM126A Proteins)) and normal alanine aminotransferase (show ALT Proteins) (ALT).
AFP mRNA level is in enriched circulating tumor cells from patients with metastatic hepatocellular carcinoma.
High serum AFP levels were significantly associated with the prevalence of metabolic syndrome in a Chinese asymptomatic population.
Contrary to expectation, Chronic Hepatitis B patients with current or recent exposure to NA therapy showed poorer performance of AFP during hepatocellular carcinoma surveillance
Protein induced by vitamin K absence or antagonist-II showed higher area under the curve than alpha-fetoprotein for diagnosis of hepatitis B virus-related hepatocellular carcinoma patients (0.901 vs 0.788).We conclude that Combining alpha-fetoprotein and protein induced by vitamin K absence or antagonist-II may improve the diagnostic value for early detection of hepatocellular carcinoma.
Equine alpha-fetoprotein seems to be an important indicator of fetal well-being in horses.
This study confirmed that alpha-fetoprotein (AFP) is present in the fetal fluids of mares during the third trimester of pregnancy; experimentally induced placentitis was associated with an elevation in maternal plasma concentrations of AFP.
This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.
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