Browse our alpha Fetoprotein Proteins (AFP)

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alpha-Fetoprotein Proteins (AFP)
On are 68 alpha-Fetoprotein (AFP) Proteins from 13 different suppliers available. Additionally we are shipping alpha Fetoprotein Antibodies (1100) and alpha Fetoprotein Kits (113) and many more products for this protein. A total of 1300 alpha Fetoprotein products are currently listed.
list all proteins Gene Name GeneID UniProt
AFP 11576 P02772
AFP 174 P02771
AFP 24177  

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alpha Fetoprotein Proteins (AFP) by Origin

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Top referenced alpha Fetoprotein Proteins

  1. Human alpha Fetoprotein Protein expressed in Human Cells - ABIN2005088 : Tomasi: Structure and function of alpha-fetoprotein. in Annual review of medicine 1977 (PubMed)

  2. Human alpha Fetoprotein Protein expressed in Human - ABIN934455 : Lee, Lee: Regression of hepatocarcinoma cells using RNA aptamer specific to alpha-fetoprotein. in Biochemical and biophysical research communications 2012 (PubMed)

  3. Human alpha Fetoprotein Protein expressed in Cell culture - ABIN573558 : Mikhaylova, Schumacher, Borutzki, Neumann, Macharadze, El-Mousleh, Wahle, Zenclussen, Kreutz: Analysis of Y-P30/Dermcidin expression and properties of the Y-P30 peptide. in BMC research notes 2014 (PubMed)

More Proteins for alpha Fetoprotein Interaction Partners

Mouse (Murine) alpha-Fetoprotein (AFP) interaction partners

  1. endogenous AFP expression in the perinatal liver is reduced in the absence of beta-catenin (show CTNNB1 Proteins), suggesting that beta-catenin (show CTNNB1 Proteins) regulates AFP during liver development.

  2. Findings indicate that AFP expressed under experimental cryptorchid conditions plays a role as a regulatory factor in spermatogenesis and in hepatic generation.

  3. AFP mRNA and VEGF-C (show VEGFC Proteins) mRNA in peripheral blood were significantly correlated with recurrence and metastasis of hepatocellular carcinoma.

  4. A DEHP treatment-induced phenotype was identified with lack of glycogen (show GYS1 Proteins) accumula-tion and intracytoplasmic localization of beta-catenin (show CTNNB1 Proteins) which was associated with increased AFP gene expression.

  5. The deficits observed in parental behavior of AFP knockout females could not be explained by any changes in olfactory function, novelty recognition or anxiety

  6. Foxa1 (show FOXA1 Proteins) acts as a pioneer transcription factor in de novo activation of Afp, by exploiting a lack of methylation at juxtaposed transposed elements

  7. The level of AFP mRNA in peripheral blood may indicate recurrence and/or metastasis after curative resection of hepatocellular carcinoma.

  8. AFP affects cell proliferation by binding its receptor to trigger the signal transduction pathway of cAMP-PKA and alter the expression of K- ras (show HRAS Proteins) p21 genes

  9. A murine Nkx2.8 (show NKX2-6 Proteins) was isolated from the Hepal-6 cell line and showed oligonucleotide binding competitive with fetoprotein transcription factor (show NR5A2 Proteins).

  10. The mouse alpha-fetoprotein promoter is repressed in HepG2 hepatoma cells by hepatocyte nuclear factor-3 (show FOXA1 Proteins)

Human alpha-Fetoprotein (AFP) interaction partners

  1. rAFP promoted growth of the human HCC (show FAM126A Proteins) cells, antagonize paclitaxel inhibition of HCC (show FAM126A Proteins) cell proliferation, suppress expression of active caspase-3 (show CASP3 Proteins), and promote expression of Ras and survivin (show BIRC5 Proteins).

  2. Measurements of serum alpha-fetoprotein (AFP) levels could be helpful in detecting progression or recurrence in treated patients with hepatitis B virus (HBV) - hepatocellular carcinoma (HCC (show FAM126A Proteins)) and normal alanine aminotransferase (show ALT Proteins) (ALT).

  3. AFP mRNA level is in enriched circulating tumor cells from patients with metastatic hepatocellular carcinoma.

  4. High serum AFP levels were significantly associated with the prevalence of metabolic syndrome in a Chinese asymptomatic population.

  5. Contrary to expectation, Chronic Hepatitis B patients with current or recent exposure to NA therapy showed poorer performance of AFP during hepatocellular carcinoma surveillance

  6. Protein induced by vitamin K absence or antagonist-II showed higher area under the curve than alpha-fetoprotein for diagnosis of hepatitis B virus-related hepatocellular carcinoma patients (0.901 vs 0.788).We conclude that Combining alpha-fetoprotein and protein induced by vitamin K absence or antagonist-II may improve the diagnostic value for early detection of hepatocellular carcinoma.

  7. AFP expression turned on prior to expression of Oct4 (show POU5F1 Proteins), Klf4 (show KLF4 Proteins), Sox2 (show SOX2 Proteins) and c-myc (show MYC Proteins), and the stemness markers CD44 (show CD44 Proteins), CD133 and EpCAM (show EPCAM Proteins) in the normal human liver L-02 cell line or CHL (show CHRDL1 Proteins) cell lines upon transfection with MCV-HBx vectors. HBx stimulates AFP expression to induce natural reprogramming of liver cells, and AFP plays a critical role in promoting the initiation of HCC (show FAM126A Proteins) progenitor/stem cells.

  8. analysis of alpha-fetoprotein producing early gastric cancer with enteroblastic differentiation

  9. Lower post-treatment AFP levels and HCV genotype 2 significantly correlated with liver fibrosis regression after sustained virological response.

  10. Increased expression of AFP resulted in the upregulation of beta-catenin (show CTNNB1 Proteins) mRNA and protein levels, while knockdown of AFP with AFP shRNA led to significantly decreased beta-catenin (show CTNNB1 Proteins) mRNA and protein levels in hepatocellular carcinoma cells.

Horse (Equine) alpha-Fetoprotein (AFP) interaction partners

  1. Equine alpha-fetoprotein seems to be an important indicator of fetal well-being in horses.

  2. This study confirmed that alpha-fetoprotein (AFP) is present in the fetal fluids of mares during the third trimester of pregnancy; experimentally induced placentitis was associated with an elevation in maternal plasma concentrations of AFP.

alpha Fetoprotein (AFP) Protein Profile

Protein Summary

This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.

Alternative names and synonyms associated with alpha Fetoprotein (AFP)

  • alpha-fetoprotein (AFP)
  • alpha fetoprotein (Afp)
  • alpha-fetoprotein (Afp)
  • FETA protein
  • HPAFP protein

Protein level used designations for alpha-Fetoprotein Proteins (AFP)

alpha-1-fetoprotein , alpha-fetoglobulin , alpha-fetoprotein , alpha-foetoprotein , chloride intracellular channel 6

704786 Macaca mulatta
11576 Mus musculus
174 Homo sapiens
403551 Canis lupus familiaris
397586 Sus scrofa
24177 Rattus norvegicus
506011 Bos taurus
422652 Gallus gallus
100034185 Equus caballus
100345865 Oryctolagus cuniculus
100728693 Cavia porcellus
461258 Pan troglodytes
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