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Human alpha Fetoprotein Protein expressed in Human - ABIN934455
Lee, Lee: Regression of hepatocarcinoma cells using RNA aptamer specific to alpha-fetoprotein. in Biochemical and biophysical research communications 2012
Human alpha Fetoprotein Protein expressed in Cell culture - ABIN573558
Mikhaylova, Schumacher, Borutzki, Neumann, Macharadze, El-Mousleh, Wahle, Zenclussen, Kreutz: Analysis of Y-P30/Dermcidin expression and properties of the Y-P30 peptide. in BMC research notes 2014
Human alpha Fetoprotein Protein expressed in Human Cells - ABIN2005088
Tomasi: Structure and function of alpha-fetoprotein. in Annual review of medicine 1977
endogenous AFP expression in the perinatal liver is reduced in the absence of beta-catenin (show CTNNB1 Proteins), suggesting that beta-catenin (show CTNNB1 Proteins) regulates AFP during liver development.
Findings indicate that AFP expressed under experimental cryptorchid conditions plays a role as a regulatory factor in spermatogenesis and in hepatic generation.
AFP mRNA and VEGF-C (show VEGFC Proteins) mRNA in peripheral blood were significantly correlated with recurrence and metastasis of hepatocellular carcinoma.
A DEHP treatment-induced phenotype was identified with lack of glycogen (show GYS1 Proteins) accumula-tion and intracytoplasmic localization of beta-catenin (show CTNNB1 Proteins) which was associated with increased AFP gene expression.
The deficits observed in parental behavior of AFP knockout females could not be explained by any changes in olfactory function, novelty recognition or anxiety
Foxa1 (show FOXA1 Proteins) acts as a pioneer transcription factor in de novo activation of Afp, by exploiting a lack of methylation at juxtaposed transposed elements
The level of AFP mRNA in peripheral blood may indicate recurrence and/or metastasis after curative resection of hepatocellular carcinoma.
AFP affects cell proliferation by binding its receptor to trigger the signal transduction pathway of cAMP-PKA and alter the expression of K- ras (show HRAS Proteins) p21 genes
A murine Nkx2.8 (show NKX2-6 Proteins) was isolated from the Hepal-6 cell line and showed oligonucleotide binding competitive with fetoprotein transcription factor (show NR5A2 Proteins).
The mouse alpha-fetoprotein promoter is repressed in HepG2 hepatoma cells by hepatocyte nuclear factor-3 (show FOXA1 Proteins)
soluble alpha-fetoprotein is a marker for Fanconi anemia (show PALB2 Proteins); FANC proteins form multi-protein complexes with BRCA proteins and are involved in homologous DNA repair [review]
Studies indicate that the experimental data on the carboxy-terminal third domain of alpha-fetoprotein (AFP-3D) interaction with cell cycle proteins in cultured MCF-7 breast cancer cells were consistent with the "in silico" findings.
we evaluated the clinical performance of LOCItrade mark-based tumor marker assays CEA (show CEACAM5 Proteins), CA19-9, CA15-3, CA125 (show MUC16 Proteins) and AFP in patients with gastrointestinal cancer and demonstrated their high diagnostic power
The definitive endoderm and foregut endoderm differentiation capabilities of Wnt (show WNT2 Proteins) pathway-modulated cells were determined based on the expression levels of the endodermal transcription factors SOX17 (show SOX17 Proteins) and FOXA2 (show FOXA2 Proteins) and those of the transcription activator GATA4 (show GATA4 Proteins) and the alpha-fetoprotein (AFP) gene, respectively.
Suggest elevated serum AFP levels may have diagnostic value for early stage hepatocellular carcinoma in Korean patients.
AFP promoted hepatocellular carcinoma cell invasion and metastasis via up-regulating expression of metastasis-related proteins.
Interference of AFP reduced AGS (show JAG1 Proteins) gastric cancer cell invasion and metastasis by enhancing anoikis sensitivity.
High serum alpha-fetoprotein is associated with colon cancer.
High serum AFP is associated with hepatitis B virus infection-related hepatocellular carcinoma.
Elevated insulin (show INS Proteins) resistance, leptin (show LEP Proteins), serum iron, ferritin (show FTL Proteins), mean platelet volume, NLR (show CXCR5 Proteins), and advanced fibrosis, as well as decreased platelet count and serum albumin (show ALB Proteins), are independently associated with an elevated AFP level in chronic hepatitis C.
Equine alpha-fetoprotein seems to be an important indicator of fetal well-being in horses.
This study confirmed that alpha-fetoprotein (AFP) is present in the fetal fluids of mares during the third trimester of pregnancy; experimentally induced placentitis was associated with an elevation in maternal plasma concentrations of AFP.
This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.
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