Browse our anti-SCP2 (SCP2) Antibodies

Full name:
anti-Sterol Carrier Protein 2 Antibodies (SCP2)
On www.antibodies-online.com are 138 Sterol Carrier Protein 2 (SCP2) Antibodies from 21 different suppliers available. Additionally we are shipping SCP2 Kits (19) and SCP2 Proteins (18) and many more products for this protein. A total of 185 SCP2 products are currently listed.
Synonyms:
AA409774, AA409893, AI586070, ATSCP2, C76618, C79031, D10Ertd73e, MBD2.8, MBD2_8, MGC77634, MGC108409, NLTP, ns-LTP, NSL-TP, NSLIPTR, OS-4, OS4, PLTP, SCP-2, SCP-CHI, SCP-X, SCP2, SCPx, STEROL CARRIER PROTEIN 2, zgc:77634

Most Popular Reactivities for anti-SCP2 (SCP2) Antibodies

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Top referenced anti-SCP2 Antibodies

  1. Human Polyclonal SCP2 Primary Antibody for EIA, IHC (p) - ABIN954693 : Dansen, Kops, Denis, Jelluma, Wanders, Bos, Burgering, Wirtz: Regulation of sterol carrier protein gene expression by the forkhead transcription factor FOXO3a. in Journal of lipid research 2004 (PubMed)
    Show all 5 references for 954693

  2. Human Polyclonal SCP2 Primary Antibody for IHC (p), WB - ABIN656448 : Shimada, Miyagawa, Kawashima, Tanaka, Honda, Honda, Tokunaga: An approach based on a genome-wide association study reveals candidate loci for narcolepsy. in Human genetics 2010 (PubMed)
    Show all 2 references for 656448

  3. Human Polyclonal SCP2 Primary Antibody for IHC (p), IHC - ABIN451521 : Atshaves, Gallegos, McIntosh, Kier, Schroeder: Sterol carrier protein-2 selectively alters lipid composition and cholesterol dynamics of caveolae/lipid raft vs nonraft domains in L-cell fibroblast plasma membranes. in Biochemistry 2003 (PubMed)

  4. Guinea Pig Polyclonal SCP2 Primary Antibody for WB - ABIN2786761 : Stanley, Versluis, Schultz, Heck, Wilmanns: Investigation of the ligand spectrum of human sterol carrier protein 2 using a direct mass spectrometry assay. in Archives of biochemistry and biophysics 2007 (PubMed)

  5. Human Polyclonal SCP2 Primary Antibody for FACS, IHC (p) - ABIN652579 : Vila, Levchenko, Korytowski, Girotti: Sterol carrier protein-2-facilitated intermembrane transfer of cholesterol- and phospholipid-derived hydroperoxides. in Biochemistry 2004 (PubMed)

More Antibodies against SCP2 Interaction Partners

Human Sterol Carrier Protein 2 (SCP2) interaction partners

  1. We (1) analyzed the structural basis of the fold and the classification of SCP2 (show CTDSP2 Antibodies) domains; (2) identified structure-determined sequence features; (3) compared the lipid binding cavity of SCP2 (show CTDSP2 Antibodies) and other lipid binding proteins; (4) surveyed proposed mechanisms of SCP2 (show CTDSP2 Antibodies) mediated lipid transfer between membranes; and (5) uncovered a possible new function of the SCP2 (show CTDSP2 Antibodies) domain as a protein-protein recognition device.

  2. imported protein sterol carrier protein 2 (SCP2) occupies only a subregion of larger peroxisomes, highlighting the heterogeneous distribution of proteins even within the peroxisome.

  3. Mice harboring a deletion of the Scp2 (show CTDSP2 Antibodies) locus present a modulated diurnal accumulation of lipids in the liver and a perturbed activation of several signaling pathways including PPARalpha (show PPARA Antibodies), SREBP, LRH-1 (show NR5A2 Antibodies), TORC1 (show CRTC1 Antibodies) and its upstream regulators.

  4. We conclude that SCP-2 (show CTDSP2 Antibodies) is a low affinity binding protein for arachidonylethanolamine that can facilitate its cellular uptake but does not contribute significantly to intracellular sequestration of AEA.

  5. The Peroxisomal targeting signal 1 in Scp2 (show CTDSP2 Antibodies) is autonomous and is essential for binding to pex5 (show PEX5 Antibodies).

  6. cellular SCP-2 (show CTDSP2 Antibodies) not only binds and translocates cholesterol but also cholesterol hydroperoxides, thus expanding their redox toxicity and signaling ranges under oxidative stress conditions

  7. Statistical analysis indicated that six genes, NFATC2, SCP2, CACNA1C, TCRA, POLE, and FAM3D, were associated with narcolepsy.

  8. data for the first time showed that while the N-terminal membrane binding domain of SCP(2 (show CTDSP2 Antibodies)) was itself inactive in mediating intermembrane sterol transfer, it nevertheless potentiated the ability of SCP(2 (show CTDSP2 Antibodies)) to enhance sterol transfer

  9. SCP2 (show CTDSP2 Antibodies) in the cellular defense against oxidative damage and found that a fluorescent fatty acid analog bound to SCP2 (show CTDSP2 Antibodies) is protected against H2O2/Cu2+-induced oxidative damage

  10. Overexpression of human SCP-2 (show CTDSP2 Antibodies) in murine fibroblasts significantly alters the sterol dynamics of caveolae/lipid rafts, but not nonlipid raft domains, to facilitate retention of cholesterol within the cell.

Mouse (Murine) Sterol Carrier Protein 2 (SCP2) interaction partners

  1. Lack of a significant decrease in the flux of HDL-[(3)H]CE to biliary FC or bile acids in FABP1(-/-) mice indicates the likely compensation of its function by an as yet unidentified mechanism. Taken together, these studies demonstrate that FABP1 and SCP2 facilitate the preferential movement of HDL-CEs to bile for final elimination

  2. Sterol Carrier Protein-2, a Nonspecific Lipid-Transfer Protein, in Intracellular Cholesterol Trafficking in Testicular Leydig Cells

  3. L-FABP (show FABP1 Antibodies) was more important in hepatic retention of bile acids, while SCP-2/SCP-x more broadly affected biliary bile acid and phospholipid levels.

  4. Loss of L-FABP (show FABP1 Antibodies) and SCP-2 (show CRISP3 Antibodies), or both induces hepatic lipid accumulation in female mice and mimics non-alcoholic fatty liver disease.

  5. CTDSP2 (show CTDSP2 Antibodies) induces p21(Cip1/Waf1 (show CDKN1A Antibodies)) through increasing the activity of Ras.

  6. SCP-2/SCP-x may function more in formation and biliary secretion of bile acid, with less impact on hepatic uptake or biliary secretion of HDL (show HSD11B1 Antibodies)-cholesterol

  7. liver fatty acid-binding protein, the single most prevalent hepatic cytosolic protein that binds cholesterol, was upregulated twofold in SCP-2 (show CRISP3 Antibodies) null hepatocytes

  8. SCP-2 expression plays a significant role in HDL-mediated cholesterol efflux by regulating the size of rapid vs. slow cholesterol efflux pools and/or eliciting concomitant upregulation of L-FABP in cultured primary hepatocytes.

  9. Effect of Scp2 (show CRISP3 Antibodies) expression on the rate of sterol transfer from lysosomal membranes, and lysosomal membrane lipid distribution.

  10. Data show that expression of sterol carrier protein-2 (SCP-2) increased fatty acid uptake and targeted fatty acid to unique lipid pools, suggesting that SCP-2 (show CRISP3 Antibodies) may effectively serve as universal fatty acid binding and trafficking protein.

Xenopus laevis Sterol Carrier Protein 2 (SCP2) interaction partners

  1. Knockdown of scp2 did not interfere with the patterning of the kidney along its proximo-distal axis, but dramatically decreased the size of the kidney, in particular the proximal tubules.

Cow (Bovine) Sterol Carrier Protein 2 (SCP2) interaction partners

  1. By trafficking cholesterol hydroperoxides and phospholipid hydroperoxides in addition to parent lipids, SCP2 may exacerbate cell injury under oxidative stress conditions. [sterol carrier protein 2, SCP2, nonspecific lipid transfer protein]

Arabidopsis thaliana Sterol Carrier Protein 2 (SCP2) interaction partners

  1. Arabidopsis SCP-2 is localised to peroxisomes and showed in vitro transfer activity of BODIPY-phosphatidylcholine (show SGMS1 Antibodies) (BODIPY-PC) from donor membranes to acceptor membranes.

SCP2 Antigen Profile

Antigen Summary

This gene encodes two proteins (SCPx) and sterol carrier protein 2 (SCP2), as a result of transcription initiation from 2 independently regulated promoters. The transcript initiated from the proximal promoter encodes the longer SCPx protein, and the transcript initiated from the distal promoter encodes the shorter SCP2 protein, with the 2 proteins sharing a common C-terminus. Evidence suggests that the SCPx protein is a peroxisome-associated thiolase that is involved in the oxidation of branched chain fatty acids, while the SCP2 protein is thought to be an intracellular lipid transfer protein. This gene is highly expressed in organs involved in lipid metabolism, and may play a role in Zellweger syndrome, in which cells are deficient in peroxisomes and have impaired bile acid synthesis. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms.

Alternative names and synonyms associated with SCP2

  • sterol carrier protein 2 (SCP2) antibody
  • CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 (Ctdsp2) antibody
  • sterol carrier protein 2, liver (Scp2) antibody
  • sterol carrier protein 2 (Scp2) antibody
  • sterol carrier protein 2 (scp2) antibody
  • SCP2 (STEROL CARRIER PROTEIN 2); oxidoreductase/ sterol carrier (SCP2) antibody
  • sterol carrier protein 2 (CC1G_13192) antibody
  • phospholipid transfer protein homolog1 (plt1) antibody
  • AA409774 antibody
  • AA409893 antibody
  • AI586070 antibody
  • ATSCP2 antibody
  • C76618 antibody
  • C79031 antibody
  • D10Ertd73e antibody
  • MBD2.8 antibody
  • MBD2_8 antibody
  • MGC77634 antibody
  • MGC108409 antibody
  • NLTP antibody
  • ns-LTP antibody
  • NSL-TP antibody
  • NSLIPTR antibody
  • OS-4 antibody
  • OS4 antibody
  • PLTP antibody
  • SCP-2 antibody
  • SCP-CHI antibody
  • SCP-X antibody
  • SCP2 antibody
  • SCPx antibody
  • STEROL CARRIER PROTEIN 2 antibody
  • zgc:77634 antibody

Protein level used designations for SCP2

non-specific lipid-transfer protein , propanoyl-CoA C-acyltransferase , sterol carrier protein X , carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 , nuclear LIM interactor-interacting factor 2 (NLI-interacting factor 2) (Protein OS-4) , small C-terminal domain phosphatase 2 , SCP-chi , nonspecific lipid transfer protein , NSL-TP , SCP-2 , SCP-X , Sterol carrier protein 2, liver , sterol carrier protein 2 , sterol carrier protein-2 , SCP2 (STEROL CARRIER PROTEIN 2); oxidoreductase/ sterol carrier , CL468_1 , CL468_1(249) , CL468_1_ov , LTP , allergen Zea m 14 , SCPX , sterol carrier protein 2, liver

GENE ID SPECIES
6342 Homo sapiens
52468 Mus musculus
20280 Mus musculus
25541 Rattus norvegicus
393839 Danio rerio
396550 Gallus gallus
456862 Pan troglodytes
479564 Canis lupus familiaris
494715 Xenopus laevis
508918 Bos taurus
548512 Xenopus (Silurana) tropicalis
834300 Arabidopsis thaliana
6004941 Coprinopsis cinerea okayama7#130
100597097 Nomascus leucogenys
542231 Zea mays
100008683 Oryctolagus cuniculus
397439 Sus scrofa
100728738 Cavia porcellus
101116445 Ovis aries
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