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Mouse (Murine) CXCR1 ELISA Kit for Sandwich ELISA - ABIN415746
Yoshizaki, Brito, Silva, Lino-Dos-Santos-Franco, Frias, E Silva, Amato-Lourenço, Saldiva, de Fátima Lopes Calvo Tibério, Mauad, Macchione: The effects of particulate matter on inflammation of respiratory system: Differences between male and female. in The Science of the total environment 2017
In this review, we summarize the biological functions and clinical significance of the CXCL8 (show IL8 ELISA Kits)-CXCR1/2 signaling pathway in cancer. Targeting CXCL8 (show IL8 ELISA Kits) or CXCR1/2 may be an attractive therapeutic strategy for tumors.
Interaction of Monomeric Interleukin-8 (show IL8 ELISA Kits) with CXCR1
first study to investigate the concentrations of CXCR-1 and CXCR-2 (show CXCR2 ELISA Kits) with the levels of IL-8 (show IL8 ELISA Kits) in colostrum and mature human milk of term and preterm newborns
High expression of CXCR1 identified a subgroup of gastric cancer patients who appeared to benefit from 5-FU based adjuvant chemotherapy .
CXCR1-NFkappaB pathway role in human hepatocyte proliferation
The analysis of IL-8 (interleukin-8 (show IL8 ELISA Kits)), CXCR1 (IL-8RA - IL-8 receptor alpha) and CXCR2 (IL-8RB (show CXCR2 ELISA Kits) - IL-8 receptor beta) expression showed that these molecules are present not only in many different types of inflammatory and endothelial cells, but also in several tumor basaloid, transitional and even few ghost cells.
Study shows that CXCR1 promoted gastric cancer cell proliferation, migration and invasion.
These data provide rationale that targeting CXCR1/2 with small molecule inhibitors may enhance chemotherapeutic efficacy for the treatment of gastric cancer.
The results showed that the expression of N-Ac-PGP receptors (CXCR1 and CXCR2) in CESCs was upregulated by N-Ac-PGP.
These data demonstrate a biological function for mouse Cxcr1 in vivo and indicate that CXCR1-dependent neutrophil effector function is a critical innate protective mechanism of fungal clearance and host survival in systemic candidiasis.
these studies define CXCR1 as a novel, noncanonical chemokine receptor that regulates pulmonary anti-Pseudomonas host defense with broad implications for cystic fibrosis (show S100A8 ELISA Kits), chronic obstructive pulmonary disease and other infectious lung diseases
CXCR1 and CXCR2 (show CXCR2 ELISA Kits) regulate hepatocyte exosome release. The mechanism utilized by CXCR1 remains elusive, but CXCR2 (show CXCR2 ELISA Kits) appears to modulate Nsm activity and resultant production of ceramide to control exosome release. CXCR1 is required for packaging of enzymes into exosomes that mediate their hepatocyte proliferative effect.
in view of recently-published experimental data obtained in NOD mice, we argue for possible Cxcr1 involvement in type 1 diabetes pathogenesi
CXCR1 expression is induced in staphylococcus aureus-infected macrophages but not in control macrophages.
Pharmacologic blockade of CXCR1/2 as well as genetic deletion of NAP-2 (show PPBP ELISA Kits) markedly reduced leukocyte shape change and intrathrombus migration.
Blockade of the CXCL1 (show CXCL1 ELISA Kits)-CXCR1/2 axis in mice improved intrahepatic islet engraftment. The CXCR1/2-mediated pathway is a regulator of islet damage.
Upon activation by CXCL8 (show IL8 ELISA Kits), CXCR1 predominantly couples to G protein-coupled receptor (show GPR34 ELISA Kits) kinase (GRK)2 (show ADRBK1 ELISA Kits) to modulate leukocyte functions.
Xiaotan Sanjie Decoction XTSJD can decrease the protein expressions of IL-8 (show IL8 ELISA Kits) and its receptors CXCR1/CXCR2 (show CXCR2 ELISA Kits) in tumor xenografts and gastric tissue adjacent to the tumor.
data suggest that CXCR1 does not mediate the proliferative effects of ELR+ CXC chemokines during liver regeneration after partial hepatectomy
The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36.
C-X-C chemokine receptor type 1
, IL-8 receptor type 1
, IL-8R A
, high affinity interleukin-8 receptor A
, interleukin 8 receptor, alpha
, interleukin-8 receptor type 1
, interleukin-8 receptor type A
, CXC chemokine receptor 1
, chemokine (C-X-C motif) receptor 2
, interleukin 8 receptor, beta
, interleukin 8 receptor alpha
, IL-8 receptor
, C-X-C motif chemokine receptor 1 S homeolog
, CXCR2 like protein
, chemokine (C-X-C motif) receptor 1 S homeolog