Browse our APOC3 Proteins (APOC3)

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Apolipoprotein C-III Proteins (APOC3)
On are 43 Apolipoprotein C-III (APOC3) Proteins from 11 different suppliers available. Additionally we are shipping APOC3 Antibodies (138) and APOC3 Kits (61) and many more products for this protein. A total of 246 APOC3 products are currently listed.
list all proteins Gene Name GeneID UniProt
APOC3 345 P02656
APOC3 11814 P33622
APOC3 24207  

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APOC3 Proteins (APOC3) by Origin

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Top referenced APOC3 Proteins

  1. Human APOC3 Protein expressed in Wheat germ - ABIN1345372 : Makino, Noguchi, Takahashi, Matsumoto, Kubo, Yamada, Imoto, Ito, Osawa, Shibasaki, Uchida, Meno, Suzuki, Okubo, Arinami, Fujieda: Apolipoprotein A-IV is a candidate target molecule for the treatment of seasonal allergic rhinitis. in The Journal of allergy and clinical immunology 2010 (PubMed)

  2. Human APOC3 Protein expressed in HEK-293 Cells - ABIN2714826 : Pan, Zhou, Mahsut, Rohm, Berejnaia, Price, Chen, Castro-Perez, Lassman, McLaren, Conway, Jensen, Thomas, Reyes-Soffer, Ginsberg, Gutstein, Cleary, Previs, Roddy: Static and turnover kinetic measurement of protein biomarkers involved in triglyceride metabolism including apoB48 and apoA5 by LC/MS/MS. in Journal of lipid research 2016 (PubMed)

More Proteins for APOC3 Interaction Partners

Human Apolipoprotein C-III (APOC3) interaction partners

  1. Gene-level meta-analysis with other studies reporting burden signals at APOC3 provides robust evidence for a replicable cardioprotective rare variant aggregation

  2. studied the associations of apoC-III, endothelial function and diabetic peripheral neuropathy

  3. Plasma levels of proprotein convertase subtilisin/kexin type 9 (PCSK9 (show PCSK9 Proteins)), apolipoprotein C-III (apoC3) and small dense low density lipoprotein cholesterol (sdLDL-C) showed significant interactions with current dyslipidemias, and were predictive in the screening.

  4. Novel sequencing techniques are detecting rare variants with larger effect sizes (eg, APOC3) , which may further improve on Cardiovascular disease risk prediction.

  5. The APOC3 rs2070666 A allele is a risk factor for NAFLD independent of obesity, dyslipidemia, and PNPLA3 rs738409, and it might contribute to increased liver fat content in Chinese Han population.

  6. ApoC-III levels are significantly associated with incident coronary artery disease risk. Elevated levels of remnant lipoproteins, small dense low-density lipoprotein, and low-grade inflammation may explain this association.

  7. The authors findings confirm an association of APOC3 with gout.

  8. Accumulating evidence indicates that apolipoprotein C-III is a multifaceted protein which not only regulates triglyceride metabolism, but also participates in the atherosclerotic lesion formation and several other pathological processes involved in atherosclerosis.

  9. Our results showed that APOC3 was closely associated with the inflammatory process in ECs, and that this process was characterized by the increased expression of TNF-alpha (show TNF Proteins). Inflammatory processes further disrupted the tight junctions (TJs) between HUVECs by causing increased expression of JAM-1 (show F11R Proteins).

  10. Transgenic mice expressing human APOC3in the C57BL/6J background have been described. The study found that hypertriglyceridemia per se is not an independent risk factor for beta cell dysfunction in ApoC3 transgenic mice.

Mouse (Murine) Apolipoprotein C-III (APOC3) interaction partners

  1. ApoC-III inhibits turnover of TG-rich lipoproteins primarily through a hepatic clearance mechanism mediated by the LDLR (show LDLR Proteins)/LRP1 (show LRP1 Proteins) axis

  2. These data strongly suggest that intestinal apoC-III is not a FoxO1 (show FOXO1 Proteins) target and support the idea that apoC-III is not regulated coordinately with hepatic apoC-III, and establishes another key aspect of apoC-III that is unique in the intestine from the liver.

  3. APOC3, whose dysregulation is liable for hypertriglyceridemia, is not a predisposing factor for linking overnutrition to NAFLD in obesity

  4. Severe hypertriglyceridaemia resulting from ApoCIII overexpression promotes restenosis and atherosclerosis

  5. Under conditions of islet insulin (show INS Proteins) resistance, locally produced apoCIII is an important diabetogenic factor involved in impairment of beta-cell function.

  6. decreased ApoAI synthesis might be accounted for the lower plasma HDL (show HSD11B1 Proteins) level in ApoCIII transgenic mice

  7. ApoCIII hyperactivates beta cell CaV1 (show CAV1 Proteins) channels through SR-BI (show SCARB1 Proteins)/beta1 integrin-dependent coactivation of PKA and Src (show SRC Proteins).

  8. Increased plasma APOC3 concentrations predispose mice to diet-induced nonalcoholic fatty liver and hepatic insulin (show INS Proteins) resistance.

  9. Glucose induces apoCIII transcription, which may represent a mechanism linking hyperglycemia, hypertriglyceridemia, and cardiovascular disease in type 2 diabetes.

  10. PGC-1beta regulates plasma triglyceride metabolism through stimulating apolipoprotein C3 (APOC3) expression and elevating APOC3 levels in circulation

Pig (Porcine) Apolipoprotein C-III (APOC3) interaction partners

  1. gene polymorphisms in APOA5 (show APOA5 Proteins) and APOC3 are associated with meat quality traits in Kele pigs

  2. changes in apolipoprotein A-I (show APOA1 Proteins) and apo (show C9orf3 Proteins) C-III mRNA were reflected in their corresponding plasma levels

Cow (Bovine) Apolipoprotein C-III (APOC3) interaction partners

  1. apoC-I (show APOC1 Proteins) and apoC-III inhibit lipolysis by displacing LPL (show LPL Proteins) from lipid emulsion particles. We also propose a role for these apolipoproteins in the irreversible inactivation of LPL (show LPL Proteins) by factors such as angptl4 (show ANGPTL4 Proteins).

APOC3 Protein Profile

Protein Summary

Apolipoprotein C-III is a very low density lipoprotein (VLDL) protein. APOC3 inhibits lipoprotein lipase and hepatic lipase\; it is thought to delay catabolism of triglyceride-rich particles. The APOA1, APOC3 and APOA4 genes are closely linked in both rat and human genomes. The A-I and A-IV genes are transcribed from the same strand, while the A-1 and C-III genes are convergently transcribed. An increase in apoC-III levels induces the development of hypertriglyceridemia.

Alternative names and synonyms associated with APOC3

  • apolipoprotein C-III (APOC3)
  • apolipoprotein C-III (Apoc3)
  • Apo-CIII protein
  • Apoc protein
  • ApoC-III protein
  • APOC3 protein
  • APOCIII protein
  • HALP2 protein

Protein level used designations for Apolipoprotein C-III Proteins (APOC3)

apolipoprotein C-III , apo-CIII , apoC-III , apolipoprotein C3 , apolipoprotein C-3 , apolipoprotein CIII

451563 Pan troglodytes
696726 Macaca mulatta
345 Homo sapiens
11814 Mus musculus
24207 Rattus norvegicus
100135481 Cavia porcellus
406187 Sus scrofa
408009 Bos taurus
442970 Canis lupus familiaris
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