Browse our anti-F2RL3 (F2RL3) Antibodies

Full name:
anti-Coagulation Factor II (Thrombin) Receptor-Like 3 Antibodies (F2RL3)
On are 108 Coagulation Factor II (Thrombin) Receptor-Like 3 (F2RL3) Antibodies from 20 different suppliers available. Additionally we are shipping F2RL3 Kits (33) and F2RL3 Proteins (5) and many more products for this protein. A total of 154 F2RL3 products are currently listed.
AA408040, F2, F2RL3, Lkb1, mLKB1, Par-4, PAR4, R75140
list all antibodies Gene Name GeneID UniProt
F2RL3 9002 Q96RI0
F2RL3 14065 O88634
F2RL3 116498 Q920E0

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anti-Human F2RL3 Antibodies:

anti-Mouse (Murine) F2RL3 Antibodies:

anti-Rat (Rattus) F2RL3 Antibodies:

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Top referenced anti-F2RL3 Antibodies

  1. Human Monoclonal F2RL3 Primary Antibody for ELISA, WB - ABIN396605 : Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. in Diabetes Care 2010 (PubMed)
    Show all 5 references for 396605

  2. Human Monoclonal F2RL3 Primary Antibody for IHC, ELISA - ABIN1724706 : Xie, Guo: Par-4 inhibits choline uptake by interacting with CHT1 and reducing its incorporation on the plasma membrane. in The Journal of biological chemistry 2004 (PubMed)
    Show all 4 references for 1724706

  3. Human Monoclonal F2RL3 Primary Antibody for ELISA, WB - ABIN563904 : Muehlschlegel, Perry, Liu, Fox, Smith, Lichtner, Collard, Shernan, Hartwig, Body, Hoffmeister: Polymorphism in the protease-activated receptor-4 gene region associates with platelet activation and perioperative myocardial injury. in American journal of hematology 2013 (PubMed)

  4. Human Polyclonal F2RL3 Primary Antibody for ELISA, WB - ABIN1536156 : Kahn, Zheng, Huang, Bigornia, Zeng, Moff, Farese, Tam, Coughlin: A dual thrombin receptor system for platelet activation. in Nature 1998 (PubMed)

  5. Human Polyclonal F2RL3 Primary Antibody for IF (p), IHC (p) - ABIN673224 : Oláh, Kálmán, Tóth, Zvara, Sántha, Ivitz, Janka, Pákáski: Proteomic Analysis of Cerebrospinal Fluid in Alzheimer's Disease: Wanted Dead or Alive. in Journal of Alzheimer's disease : JAD 2014 (PubMed)

  6. Human Polyclonal F2RL3 Primary Antibody for ICC, FACS - ABIN1742018 : Ossovskaya, Bunnett: Protease-activated receptors: contribution to physiology and disease. in Physiological reviews 2004 (PubMed)

More Antibodies against F2RL3 Interaction Partners

Human Coagulation Factor II (Thrombin) Receptor-Like 3 (F2RL3) interaction partners

  1. F2RL3 variants have the potential to markedly alter platelet PAR4 (show PAWR Antibodies) reactivity particularly after exposure to therapeutic PAR1 (show MARK2 Antibodies) antagonists.

  2. these findings are the first to show that internalization of activated PAR4 (show PAWR Antibodies) is linked to proper ERK1/2 (show MAPK1/3 Antibodies) and Akt (show AKT1 Antibodies) activation.

  3. an intracellular PAR4 C-terminal motif that regulates calcium signaling and beta-arrestin interactions, was identified.

  4. the contribution of PAR1 (show MARK2 Antibodies) and PAR4 (show PAWR Antibodies) to thrombin (show F2 Antibodies)-mediated activation of the platelet fibrin receptor (GPIIbIIIa), is reported.

  5. Suppression of PAR4 (show PAWR Antibodies) expression has no significant effect on the proliferation of SW620 cells, but can inhibit the migration of the cells.

  6. Both GPIbalpha (show GP1BA Antibodies) and PAR4 (show PAWR Antibodies) are required for thrombin (show F2 Antibodies)-induced reactive oxygen species formation in human platelets.

  7. Bladder PAR (show JTB Antibodies) activation elicits urothelial MIF (show AMH Antibodies) release and urothelial MIF (show AMH Antibodies) receptor signaling at least partly through CXCR4 (show CXCR4 Antibodies) to result in abdominal hypersensitivity without overt bladder inflammation

  8. protease-activated receptor 4 and Trefoil factor 2 (show TFF2 Antibodies) are expressed in human colorectal cancer

  9. The PAR4 (show PAWR Antibodies) expression and activation via intracellular signaling pathways and the role of PAR4 (show PAWR Antibodies) signaling pathways in the development and maintenance of pain.

  10. This review summarizes the roles of PAR4 (show PAWR Antibodies) in coagulation and other extracellular protease pathways.

Mouse (Murine) Coagulation Factor II (Thrombin) Receptor-Like 3 (F2RL3) interaction partners

  1. mitochondrial dysfunction triggers LKB1 (show STK11 Antibodies)-mediated AMPK (show PRKAA1 Antibodies) activation, which stimulates Sirt2 (show SIRT2 Antibodies) phosphorylation, leading to activation of mTOR (show FRAP1 Antibodies)-RAPTOR (show RPTOR Antibodies) and Glut1 (show SLC2A1 Antibodies)-mediated glucose uptake.

  2. these data demonstrated that LKB1 (show STK11 Antibodies)/AMPK (show PRKAA1 Antibodies) signaling pathway activation improved the survival of diabetic mice complicated with endotoxemia. Thus, LKB1 (show STK11 Antibodies)/AMPK (show PRKAA1 Antibodies) signaling pathway may serve as a potentially useful therapeutic target for severe infection in diabetic patients.

  3. Data show that the serine/threonine kinase (show CDK4 Antibodies) LKB1 (show STK11 Antibodies) regulates mitochondrial calcium uniporter (MCU (show MCU Antibodies))-expression, mitochondria-dependent Ca2 (show CA2 Antibodies)+ clearance, and thereby, presynaptic release properties.

  4. LKB1 (show STK11 Antibodies) deficiency in LKB1 (show STK11 Antibodies)(Pax2 (show PAX2 Antibodies)) CKO mice disrupted hair cell planar polarity during embryonic development. The results suggest that LKB1 (show STK11 Antibodies) is required in planar cell polarity formation in cochlear hair cells in mice.

  5. silencing of the LKB1 (show STK11 Antibodies) tumor suppressor affects the delamination of pre-migratory cephalic neural crest cells from the neural primordium as well as their polarization and survival, thus resulting in severe facial and brain defects

  6. these findings are the first to show that internalization of activated PAR4 is linked to proper ERK1/2 (show MAPK1/3 Antibodies) and Akt (show AKT1 Antibodies) activation.

  7. LKB1 (show STK11 Antibodies) complex proteins have a role in myofilament function and myocellular "energy" sensing in the heart

  8. identification of a network linking metabolic and epigenetic alterations that is central to oncogenic transformation downstream of the liver kinase B1 (LKB1 (show STK11 Antibodies), also known as STK11 (show STK11 Antibodies)) tumour suppressor, an integrator of nutrient availability, metabolism and growth

  9. The lack of LKB1 (show STK11 Antibodies) in skeletal muscle leads to an increased inflammatory state.

  10. Partial deficiency of cardiac LKB1 (show STK11 Antibodies) promotes the adverse effects of a high-fat, high-sucrose diet on the myocardium, leading to worsening of diastolic function and the de novo appearance of systolic dysfunction.

F2RL3 Antigen Profile

Antigen Summary

Coagulation factor II (thrombin) receptor-like 3 (F2RL3) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL3 is also a member of the protease-activated receptor family. F2RL3 is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. F2RL3 is activated by thrombin and trypsin.

Alternative names and synonyms associated with F2RL3

  • coagulation factor II (thrombin) receptor-like 3 (F2RL3) antibody
  • coagulation factor II (thrombin) (F2) antibody
  • coagulation factor II (thrombin) receptor-like 3 (F2rl3) antibody
  • serine/threonine kinase 11 (Stk11) antibody
  • AA408040 antibody
  • F2 antibody
  • F2RL3 antibody
  • Lkb1 antibody
  • mLKB1 antibody
  • Par-4 antibody
  • PAR4 antibody
  • R75140 antibody

Protein level used designations for F2RL3

proteinase-activated receptor 4 , coagulation factor II (thrombin) receptor-like 3 , prothrombin , coagulation factor II (thrombin) , PAR-4 , protease-activated receptor-4 , thrombin receptor-like 3 , coagulation factor II receptor-like 3 , protease-activated receptor 4 , LKB1 short isoform , liver kinase B1 homolog , serine/threonine-protein kinase 11 , serine/threonine-protein kinase LKB1 , serine/threonine-protein kinase STK11

538963 Bos taurus
484846 Canis lupus familiaris
420139 Gallus gallus
718843 Macaca mulatta
455829 Pan troglodytes
100173859 Pongo abelii
451158 Pan troglodytes
9002 Homo sapiens
14065 Mus musculus
116498 Rattus norvegicus
20869 Mus musculus
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