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Browse our F2RL3 Proteins (F2RL3)

Full name:
Coagulation Factor II (Thrombin) Receptor-Like 3 Proteins (F2RL3)
On are 5 Coagulation Factor II (Thrombin) Receptor-Like 3 (F2RL3) Proteins from 4 different suppliers available. Additionally we are shipping F2RL3 Antibodies (111) and F2RL3 Kits (31) and many more products for this protein. A total of 155 F2RL3 products are currently listed.
AA408040, F2, F2RL3, Lkb1, mLKB1, Par-4, PAR4, R75140
list all proteins Gene Name GeneID UniProt
F2RL3 9002 Q96RI0
F2RL3 14065 O88634
Rat F2RL3 F2RL3 116498 Q920E0

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F2RL3 Proteins (F2RL3) by Origin

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More Proteins for F2RL3 Interaction Partners

Human Coagulation Factor II (Thrombin) Receptor-Like 3 (F2RL3) interaction partners

  1. these findings are the first to show that internalization of activated PAR4 (show PAWR Proteins) is linked to proper ERK1/2 and Akt (show AKT1 Proteins) activation.

  2. an intracellular PAR4 C-terminal motif that regulates calcium signaling and beta-arrestin interactions, was identified.

  3. the contribution of PAR1 (show MARK2 Proteins) and PAR4 (show PAWR Proteins) to thrombin (show F2 Proteins)-mediated activation of the platelet fibrin receptor (GPIIbIIIa), is reported.

  4. Suppression of PAR4 (show PAWR Proteins) expression has no significant effect on the proliferation of SW620 cells, but can inhibit the migration of the cells.

  5. Both GPIbalpha (show GP1BA Proteins) and PAR4 (show PAWR Proteins) are required for thrombin (show F2 Proteins)-induced reactive oxygen species formation in human platelets.

  6. Bladder PAR (show JTB Proteins) activation elicits urothelial MIF (show AMH Proteins) release and urothelial MIF (show AMH Proteins) receptor signaling at least partly through CXCR4 (show CXCR4 Proteins) to result in abdominal hypersensitivity without overt bladder inflammation

  7. protease-activated receptor 4 and Trefoil factor 2 (show TFF2 Proteins) are expressed in human colorectal cancer

  8. The PAR4 (show PAWR Proteins) expression and activation via intracellular signaling pathways and the role of PAR4 (show PAWR Proteins) signaling pathways in the development and maintenance of pain.

  9. This review summarizes the roles of PAR4 (show PAWR Proteins) in coagulation and other extracellular protease pathways.

  10. Findings suggested that F2RL3 methylation is a very strong predictor of lung cancer risk and mortality, particularly at older age.

Mouse (Murine) Coagulation Factor II (Thrombin) Receptor-Like 3 (F2RL3) interaction partners

  1. LKB1 (show STK11 Proteins) deficiency in LKB1 (show STK11 Proteins)(Pax2 (show PAX2 Proteins)) CKO mice disrupted hair cell planar polarity during embryonic development. The results suggest that LKB1 (show STK11 Proteins) is required in planar cell polarity formation in cochlear hair cells in mice.

  2. silencing of the LKB1 (show STK11 Proteins) tumor suppressor affects the delamination of pre-migratory cephalic neural crest cells from the neural primordium as well as their polarization and survival, thus resulting in severe facial and brain defects

  3. these findings are the first to show that internalization of activated PAR4 is linked to proper ERK1/2 and Akt (show AKT1 Proteins) activation.

  4. LKB1 (show STK11 Proteins) complex proteins have a role in myofilament function and myocellular "energy" sensing in the heart

  5. identification of a network linking metabolic and epigenetic alterations that is central to oncogenic transformation downstream of the liver kinase B1 (LKB1 (show STK11 Proteins), also known as STK11 (show STK11 Proteins)) tumour suppressor, an integrator of nutrient availability, metabolism and growth

  6. The lack of LKB1 (show STK11 Proteins) in skeletal muscle leads to an increased inflammatory state.

  7. Partial deficiency of cardiac LKB1 (show STK11 Proteins) promotes the adverse effects of a high-fat, high-sucrose diet on the myocardium, leading to worsening of diastolic function and the de novo appearance of systolic dysfunction.

  8. Rapid activation of AMPK (show PRKAA1 Proteins) was detected after exposure of cortical neuronal cultures to zinc, which was induced by LKB1 (show STK11 Proteins) activation but not increased intracellular AMP (show TMPRSS5 Proteins) levels or CaMKKbeta activation.

  9. Par4 deficiency offers cardioprotection after acute ischemia reperfusion injury.

  10. We proposed that LKB1 (show STK11 Proteins) regulates cerebellar development by controlling GCPs proliferation through Shh (show SHH Proteins) signalling during cerebellar development.

F2RL3 Protein Profile

Protein Summary

Coagulation factor II (thrombin) receptor-like 3 (F2RL3) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL3 is also a member of the protease-activated receptor family. F2RL3 is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. F2RL3 is activated by thrombin and trypsin.

Alternative names and synonyms associated with F2RL3

  • coagulation factor II (thrombin) receptor-like 3 (F2RL3)
  • coagulation factor II (thrombin) (F2)
  • coagulation factor II (thrombin) receptor-like 3 (F2rl3)
  • serine/threonine kinase 11 (Stk11)
  • AA408040 protein
  • F2 protein
  • F2RL3 protein
  • Lkb1 protein
  • mLKB1 protein
  • Par-4 protein
  • PAR4 protein
  • R75140 protein

Protein level used designations for F2RL3

proteinase-activated receptor 4 , coagulation factor II (thrombin) receptor-like 3 , prothrombin , coagulation factor II (thrombin) , PAR-4 , protease-activated receptor-4 , thrombin receptor-like 3 , coagulation factor II receptor-like 3 , protease-activated receptor 4 , LKB1 short isoform , liver kinase B1 homolog , serine/threonine-protein kinase 11 , serine/threonine-protein kinase LKB1 , serine/threonine-protein kinase STK11

538963 Bos taurus
484846 Canis lupus familiaris
420139 Gallus gallus
718843 Macaca mulatta
455829 Pan troglodytes
100173859 Pongo abelii
451158 Pan troglodytes
9002 Homo sapiens
14065 Mus musculus
116498 Rattus norvegicus
20869 Mus musculus
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