Browse our RPS6 Proteins (RPS6)

Full name:
Ribosomal Protein S6 Proteins (RPS6)
On are 20 Ribosomal Protein S6 (RPS6) Proteins from 3 different suppliers available. Additionally we are shipping RPS6 Antibodies (307) and RPS6 Kits (24) and many more products for this protein. A total of 363 RPS6 products are currently listed.
(Rp)S6, air8, air[8], anon-WO02059370.61, CG10944, Dmel\\CG10944, DS6, hen, l(1)air8, l(1)air[8], l(1)hen, M(1)7BC, M(1)7C, pp30, Rp S6, rps6, rps6a, S6, S6R
list all proteins Gene Name GeneID UniProt
RPS6 6194 P62753
RPS6 20104 P62754
RPS6 29304 P62755

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RPS6 Proteins (RPS6) by Origin

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Top referenced RPS6 Proteins

  1. Human RPS6 Protein expressed in Wheat germ - ABIN1318818 : Lee, Mustafa, Hudes, Kruger: Hydroxychloroquine Destabilizes Phospho-S6 in Human Renal Carcinoma Cells. in PLoS ONE 2015 (PubMed)

More Proteins for RPS6 Interaction Partners

Human Ribosomal Protein S6 (RPS6) interaction partners

  1. the aggregation of rpS6 at the nucleolus correlates to the phasing of cell cycle, beginning to concentrate in the nucleolus at later S phase and disaggregate at M phase.

  2. Data suggest ribosomal protein S6 (rpS6) as tumor marker for renal cell carcinoma (show MOK Proteins).

  3. Hyperphosphorylation of ribosomal protein S6 predicts unfavorable clinical survival in non-small cell lung cancer

  4. p-rpS6 is a robust post-treatment indicator of HER2 (show ERBB2 Proteins) pathway-targeted therapy resistance

  5. Resistance to Selumetinib (AZD6244) in colorectal cancer cell lines is mediated by p70S6K (show RPS6KB1 Proteins) and RPS6 activation.

  6. Tanshinone IIA inhibits HIF-1alpha (show HIF1A Proteins) and VEGF (show VEGFA Proteins) expression in breast cancer cells via mTOR (show FRAP1 Proteins)/p70S6K (show RPS6KB1 Proteins)/RPS6/4E-BP1 (show EIF4EBP1 Proteins) signaling pathway.

  7. The expression levels of phospho-mTOR (show FRAP1 Proteins) and phospho-S6RP may be potential predictive biomarkers for efficacy of everolimus in patients with metastatic renal cell carcinoma (show MOK Proteins).

  8. we report that phosphorylation of ribosomal protein S6 is greatly increased in BRCA1 deficient cells resistant to PARP inhibition

  9. High Ribosomal Protein S6 is associated with renal cell carcinoma (show MOK Proteins) metastases.

  10. a novel mechanism for modulating the RPS6 function by PP1 (show PPA1 Proteins) and ATM (show ATM Proteins) which regulates cell growth and survival in response to DNA-damage stim

Mouse (Murine) Ribosomal Protein S6 (RPS6) interaction partners

  1. in adult cardiac myocytes 4-hydroxy-trans-2-nonenal stimulates protein synthesis by activation of mTORC1-p70S6K (show RPS6KB1 Proteins)-RPS6 signaling

  2. rpS6 phosphorylation facilitates the increase in cyclin D1 (show CCND1 Proteins) and decrease in cyclin E1 (show CCNE1 Proteins) that underlie the hypertrophic nature of uninephrectomy-induced kidney growth.

  3. The mTORC1 effectors, RPS6 and eIF4E, play distinct roles and are both necessary for AKT/Ras hepatocarcinogenesis.

  4. Activation of mTORC2 (show CRTC2 Proteins) plays a pivotal role in cardioprotection, and Rps6 is a convergence point of cardioprotective signaling, providing positive feedback regulation of mTORC2 (show CRTC2 Proteins)/Akt (show AKT1 Proteins) signaling.

  5. Data indicate that the mTOR (show FRAP1 Proteins) activity evaluated by the phosphorylation status of ribosomal protein S6, and phospho-S6 (pS6) levels was found declined shortly after rapamycin treatment in both cortex and hippocampus.

  6. Downregulation of HELZ reduced translational initiation, resulting in the disassembly of polysomes, in a reduction of cell proliferation and hypophosphorylation of ribosomal protein S6.

  7. regulatory protein (show TGFB1 Proteins) S6 phosphorylation is controlled by Akt (show AKT1 Proteins), downstream to PI-3K and upstream to mTOR (show FRAP1 Proteins) in an IL2 (show IL2 Proteins)-mediated signal transduction pathway

  8. Rps6 phosphorylation is a determinant of cell size and glucose homeostasis.

  9. the phosphorylation of Tyr (show TYR Proteins)(1077) on LepRb (show LEPR Proteins) during receptor activation, substantiate the hypothalamic regulation of STAT5 (show STAT5A Proteins) and S6 by leptin (show LEP Proteins), and define the alternate LepRb (show LEPR Proteins) signaling pathways

  10. rpS6, especially in its unphosphorylated form, is a selective mediator of TRAIL-induced apoptosis

Pig (Porcine) Ribosomal Protein S6 (RPS6) interaction partners

  1. Arg, Leu, and Gln act coordinately to stimulate proliferation of pTr cells through activation of the MTOR (show FRAP1 Proteins)-RPS6K-RPS6-EIF4EBP1 (show EIF4EBP1 Proteins) signal transduction pathway.

Cow (Bovine) Ribosomal Protein S6 (RPS6) interaction partners

  1. molecular network including eIF1AX (show EIF1AY Proteins), RPS7 (show RPS7 Proteins), and 14-3-3gamma (show YWHAG Proteins) regulates protein translation and cell proliferation in BMECs.

RPS6 Protein Profile

Protein Summary

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

Alternative names and synonyms associated with RPS6

  • Ribosomal protein S6 (RpS6)
  • 30S ribosomal protein S6 (rps6)
  • Protein RPS-6 (rps-6)
  • ribosomal protein S6 (RPS6)
  • ribosomal protein S6 (Rps6)
  • ribosomal protein S6 (rps6-a)
  • ribosomal protein S6 (LOC100533219)
  • S6 ribosomal protein (LOC100135859)
  • (Rp)S6 protein
  • air8 protein
  • air[8] protein
  • anon-WO02059370.61 protein
  • CG10944 protein
  • Dmel\\CG10944 protein
  • DS6 protein
  • hen protein
  • l(1)air8 protein
  • l(1)air[8] protein
  • l(1)hen protein
  • M(1)7BC protein
  • M(1)7C protein
  • pp30 protein
  • Rp S6 protein
  • rps6 protein
  • rps6a protein
  • S6 protein
  • S6R protein

Protein level used designations for Ribosomal Protein S6 Proteins (RPS6)

CG10944-PA , CG10944-PB , RpS6-PA , RpS6-PB , hemocytes enlarged , lethal(1)aberrant immune response[8] , lethal-(1)-haemocytes enlarged , lethal-aberrant-immune-response-8 , minute , minute (1) 7BC , ribosomal protein S6 , 40S ribosomal protein S6 , phosphoprotein NP33 , ribosomal Protein, Small subunit (28.1 kD) (rps-6) , ribosomal protein S6 a

31700 Drosophila melanogaster
801680 Cyanophora paradoxa
173260 Caenorhabditis elegans
6194 Homo sapiens
396148 Gallus gallus
20104 Mus musculus
29304 Rattus norvegicus
100038023 Sus scrofa
787914 Bos taurus
474722 Canis lupus familiaris
101098495 Felis catus
100729373 Cavia porcellus
380281 Xenopus laevis
100533219 Aplysia californica
100135859 Oncorhynchus mykiss
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