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Full name:
Solute Carrier Family 29 (Nucleoside Transporters), Member 1 ELISA Kits (SLC29A1)
On www.antibodies-online.com are 6 Solute Carrier Family 29 (Nucleoside Transporters), Member 1 (SLC29A1) ELISA Kits from 4 different suppliers available. Additionally we are shipping SLC29A1 Antibodies (151) and SLC29A1 Proteins (4) and many more products for this protein. A total of 171 SLC29A1 products are currently listed.
Synonyms:
1200014D21Rik, AA407560, ENT1, rENT1
list all ELISA KIts Gene Name GeneID UniProt
SLC29A1 2030 Q99808
SLC29A1 63997 O54698
SLC29A1 63959 Q9JIM1

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Human Solute Carrier Family 29 (Nucleoside Transporters), Member 1 (SLC29A1) interaction partners

  1. CYR61 (show CYR61 ELISA Kits) negatively regulates the nucleoside transporters hENT1 and hCNT3 (show SLC28A3 ELISA Kits) in pancreatic ductal adenocarcinoma.

  2. Chronic inhibition of ENT1 or by genetic removal of ENT1 enhanced the survival of R6/2 mice. Collectively, adenosine homeostasis and ENT1 expression are altered in Huntington's disease (HD). The inhibition of ENT1 can enhance extracellular adenosine level and be a potential therapeutic approach for treating HD.

  3. Combined expression analyses of hENT1, TS, and DPD (show DPYD ELISA Kits) may predict long-term outcomes in patients with borderline resectable pancreatic cancer after neoadjuvant chemoradiotherapy

  4. studies describe 2 novel modes of action of ticagrelor, inhibition of platelet ENT1 and inverse agonism at the P2Y12R that contribute to its effective inhibition of platelet activation.

  5. These findings suggest that ENT1 is regulated via receptor-dependent calcium-linked pathways resulting in an alteration of purine flux, which may modulate purinergic signaling and influence NA drug efficacy.

  6. SLC29A1 rs760370 and KLF12 (show KLF12 ELISA Kits) rs9543524 SNPs are associated with treatment induced thrombocytopenia in chronic hepatitis C patients treated with PEGIFN2b/ribavirin/combination.

  7. interaction of Met(33) (involved in dipyridamole binding) with BCR-ABL (show ABL1 ELISA Kits) inhibitors and reduced interaction with M33A mutant hENT1.

  8. Authors clearly demonstrate that ribavirin uptake in primary human hepatocytes is variable and correlates with ENT1 expression.

  9. A pro-apoptotic effect of verapamil was observed in L3.6pl cells, but not in L3.6plGres cells, which was linked to their differential expression of P-gp (show ABCB4 ELISA Kits) and equilibrative nucleoside transporter-1 (ENT-1).

  10. Human ENT1 proteins exist as two sub-populations, and cytidine pre-treatment leads to the internalization of one population.

Mouse (Murine) Solute Carrier Family 29 (Nucleoside Transporters), Member 1 (SLC29A1) interaction partners

  1. Chronic inhibition of ENT1 or by genetic removal of ENT1 enhanced the survival of R6/2 mice. Collectively, adenosine homeostasis and ENT1 expression are altered in Huntington's disease (HD). The inhibition of ENT1 can enhance extracellular adenosine level and be a potential therapeutic approach for treating HD.

  2. results establish Augustine as a new blood group (show DARC ELISA Kits) system and place SLC29A1 as a new candidate gene for idiopathic disorders characterized with ectopic calcification/mineralization.

  3. Findings demonstrate that ENT1 regulates GFAP (show GFAP ELISA Kits) expression and possibly astrocyte function

  4. ENT1-regulated adenosine signaling plays an essential role in lumbar spine and femur bone density

  5. findings implicate ENT1 in liver protection from ischemia and reperfusion injury and suggest ENT inhibitors may be of benefit in the prevention or treatment of ischemic liver injury

  6. This is the first report of a role for ENT1 in regulating the calcification of soft tissues. ENT1(-/-) mice may be a useful model for investigating pathogenesis and evaluating therapeutics for the prevention of mineralization in DISH and related disord

  7. It was shown that the responsiveness of kidney tubules and glomeruli is significantly attenuated in the absence of ENT1, leading to changes of extracellular adenosine levels in the juxtaglomerular apparatus interstitium.

  8. This study demonstrated that the A2AR (show ADORA2A ELISA Kits) antagonist ZM241385 dampened protein kinase A activity-mediated signaling in the DMS and promoted excessive ethanol drinking in ENT1(+/+) mice

  9. Perfusions without sodium drastically reduced the intestinal loss of ribavirin in both wild-type and Ent1(-/-) mice.

  10. These studies identify ENT1 and adenosine receptors as key to the process of reestablishing renal perfusion following ischemic acute kidney injury.

SLC29A1 Antigen Profile

Antigen Summary

This gene is a member of the equilibrative nucleoside transporter family. The gene encodes a transmembrane glycoprotein that localizes to the plasma and mitochondrial membranes and mediates the cellular uptake of nucleosides from the surrounding medium. The protein is categorized as an equilibrative (as opposed to concentrative) transporter that is sensitive to inhibition by nitrobenzylthioinosine (NBMPR). Nucleoside transporters are required for nucleotide synthesis in cells that lack de novo nucleoside synthesis pathways, and are also necessary for the uptake of cytotoxic nucleosides used for cancer and viral chemotherapies. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene.

Alternative names and synonyms associated with SLC29A1

  • solute carrier family 29 (equilibrative nucleoside transporter), member 1 (SLC29A1) Elisa Kit
  • solute carrier family 29 (equilibrative nucleoside transporter), member 1 (Slc29a1) Elisa Kit
  • solute carrier family 29 (nucleoside transporters), member 1 (Slc29a1) Elisa Kit
  • 1200014D21Rik Elisa Kit
  • AA407560 Elisa Kit
  • ENT1 Elisa Kit
  • rENT1 Elisa Kit

Protein level used designations for SLC29A1

equilibrative NBMPR-sensitive nucleoside transporter , equilibrative nitrobenzylmercaptopurine riboside (NBMPR)-sensitive nucleoside transporter , equilibrative nitrobenzylmercaptopurine riboside-sensitive nucleoside transporter , equilibrative nucleoside transporter 1 , nucleoside transporter, es-type , solute carrier family 29 (nucleoside transporters), member 1 , solute carrier family 29 member 1 , solute carrier family 29, member 1 , NBMPR-sensitive equilibrative nucleoside transporter , equilibrative nucleoside transporter 1 variant delta 11

GENE ID SPECIES
2030 Homo sapiens
63997 Rattus norvegicus
63959 Mus musculus
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