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Browse our SLC29A1 Proteins (SLC29A1)

Full name:
Solute Carrier Family 29 (Nucleoside Transporters), Member 1 Proteins (SLC29A1)
On www.antibodies-online.com are 4 Solute Carrier Family 29 (Nucleoside Transporters), Member 1 (SLC29A1) Proteins from 3 different suppliers available. Additionally we are shipping SLC29A1 Antibodies (152) and SLC29A1 Kits (5) and many more products for this protein. A total of 170 SLC29A1 products are currently listed.
Synonyms:
1200014D21Rik, AA407560, ENT1, rENT1
list all proteins Gene Name GeneID UniProt
SLC29A1 2030 Q99808
Rat SLC29A1 SLC29A1 63997 O54698
SLC29A1 63959 Q9JIM1

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SLC29A1 Proteins (SLC29A1) by Origin

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Top referenced SLC29A1 Proteins

  1. Human SLC29A1 Protein expressed in Wheat germ - ABIN1320347 : Greenhalf, Ghaneh, Neoptolemos, Palmer, Cox, Lamb, Garner, Campbell, Mackey, Costello, Moore, Valle, McDonald, Carter, Tebbutt, Goldstein, Shannon, Dervenis, Glimelius, Deakin, Charnley, Lacaine et al.: Pancreatic cancer hENT1 expression and survival from gemcitabine in patients from the ESPAC-3 trial. ... in Journal of the National Cancer Institute 2014 (PubMed)

More Proteins for SLC29A1 Interaction Partners

Human Solute Carrier Family 29 (Nucleoside Transporters), Member 1 (SLC29A1) interaction partners

  1. These findings suggest that ENT1 is regulated via receptor-dependent calcium-linked pathways resulting in an alteration of purine flux, which may modulate purinergic signaling and influence NA drug efficacy.

  2. SLC29A1 rs760370 and KLF12 (show KLF12 Proteins) rs9543524 SNPs are associated with treatment induced thrombocytopenia in chronic hepatitis C patients treated with PEGIFN2b/ribavirin/combination.

  3. interaction of Met(33) (involved in dipyridamole binding) with BCR-ABL (show ABL1 Proteins) inhibitors and reduced interaction with M33A mutant hENT1.

  4. Authors clearly demonstrate that ribavirin uptake in primary human hepatocytes is variable and correlates with ENT1 expression.

  5. A pro-apoptotic effect of verapamil was observed in L3.6pl cells, but not in L3.6plGres cells, which was linked to their differential expression of P-gp (show ABCB4 Proteins) and equilibrative nucleoside transporter-1 (ENT-1).

  6. Human ENT1 proteins exist as two sub-populations, and cytidine pre-treatment leads to the internalization of one population.

  7. Results showed that both SLC29A1 and SLC29A2 (show SLC29A2 Proteins) were expressed at lower levels in colon cancer cell lines originating from metastatic sites than from primary sites.

  8. Direct evidence for apical localization of ENT1 and integral expression of ENT2 (show SLC29A2 Proteins) in intestinal epithelial cells.

  9. mRNA expression of ENT1 was closely associated with cell proliferation and varied in seven non-Hodgkin lymphoma cell lines.

  10. Low ENT1 expression is associated with periampullary adenocarcinoma.

Mouse (Murine) Solute Carrier Family 29 (Nucleoside Transporters), Member 1 (SLC29A1) interaction partners

  1. results establish Augustine as a new blood group (show DARC Proteins) system and place SLC29A1 as a new candidate gene for idiopathic disorders characterized with ectopic calcification/mineralization.

  2. Findings demonstrate that ENT1 regulates GFAP (show GFAP Proteins) expression and possibly astrocyte function

  3. ENT1-regulated adenosine signaling plays an essential role in lumbar spine and femur bone density

  4. findings implicate ENT1 in liver protection from ischemia and reperfusion injury and suggest ENT inhibitors may be of benefit in the prevention or treatment of ischemic liver injury

  5. This is the first report of a role for ENT1 in regulating the calcification of soft tissues. ENT1(-/-) mice may be a useful model for investigating pathogenesis and evaluating therapeutics for the prevention of mineralization in DISH and related disord

  6. It was shown that the responsiveness of kidney tubules and glomeruli is significantly attenuated in the absence of ENT1, leading to changes of extracellular adenosine levels in the juxtaglomerular apparatus interstitium.

  7. This study demonstrated that the A2AR (show ADORA2A Proteins) antagonist ZM241385 dampened protein kinase A activity-mediated signaling in the DMS and promoted excessive ethanol drinking in ENT1(+/+) mice

  8. Perfusions without sodium drastically reduced the intestinal loss of ribavirin in both wild-type and Ent1(-/-) mice.

  9. These studies identify ENT1 and adenosine receptors as key to the process of reestablishing renal perfusion following ischemic acute kidney injury.

  10. Mice lacking ENT1 exhibit increased glutamate (show GRIN1 Proteins) levels in the nucleus accumbens as well as increased ethanol drinking behaviors.

SLC29A1 Protein Profile

Protein Summary

This gene is a member of the equilibrative nucleoside transporter family. The gene encodes a transmembrane glycoprotein that localizes to the plasma and mitochondrial membranes and mediates the cellular uptake of nucleosides from the surrounding medium. The protein is categorized as an equilibrative (as opposed to concentrative) transporter that is sensitive to inhibition by nitrobenzylthioinosine (NBMPR). Nucleoside transporters are required for nucleotide synthesis in cells that lack de novo nucleoside synthesis pathways, and are also necessary for the uptake of cytotoxic nucleosides used for cancer and viral chemotherapies. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene.

Alternative names and synonyms associated with SLC29A1

  • solute carrier family 29 (equilibrative nucleoside transporter), member 1 (SLC29A1)
  • solute carrier family 29 (equilibrative nucleoside transporter), member 1 (Slc29a1)
  • solute carrier family 29 (nucleoside transporters), member 1 (Slc29a1)
  • 1200014D21Rik protein
  • AA407560 protein
  • ENT1 protein
  • rENT1 protein

Protein level used designations for SLC29A1

equilibrative NBMPR-sensitive nucleoside transporter , equilibrative nitrobenzylmercaptopurine riboside (NBMPR)-sensitive nucleoside transporter , equilibrative nitrobenzylmercaptopurine riboside-sensitive nucleoside transporter , equilibrative nucleoside transporter 1 , nucleoside transporter, es-type , solute carrier family 29 (nucleoside transporters), member 1 , solute carrier family 29 member 1 , solute carrier family 29, member 1 , NBMPR-sensitive equilibrative nucleoside transporter , equilibrative nucleoside transporter 1 variant delta 11

GENE ID SPECIES
2030 Homo sapiens
63997 Rattus norvegicus
63959 Mus musculus
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