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Human TJP1 ELISA Kit for Sandwich ELISA - ABIN578077
Jayashree, Bibin, Prabhu, Shanthirani, Gokulakrishnan, Lakshmi, Mohan, Balasubramanyam: Increased circulatory levels of lipopolysaccharide (LPS) and zonulin signify novel biomarkers of proinflammation in patients with type 2 diabetes. in Molecular and cellular biochemistry 2014
Aberrant expression of the tight junction molecules claudin-1 (show CLDN7 ELISA Kits) and zonula occludens-1 mediates cell growth and invasion in oral squamous cell carcinoma cells.
ZO-1-occludin (show OCLN ELISA Kits) interactions regulate multiple phases of epithelial polarization by providing cell-intrinsic signals that are required for single lumen formation.
It is postulated that ZO-1, when not phosphorylated by PKC, keeps Octn2 (show SLC22A5 ELISA Kits) in an active state, while elimination of this binding in DeltaPDZ mutant or after ZO-1 phosphorylation leads to diminution of Octn2 (show SLC22A5 ELISA Kits) activity.
Results uncovered ZO-1 as part of a signaling node activated by VEGF (show VEGFA ELISA Kits), but not Ang-1 (show ANGPT1 ELISA Kits), that specifically modulates endothelial cells proliferation during angiogenesis.
Data suggest that long noncoding RNA PlncRNA1 and microRNA miR (show MLXIP ELISA Kits)-34c bound together to regulate the expressions of MAZ, ZO-1 and occludin (show OCLN ELISA Kits).
STAT3 activation downregulates the ZO-1 and occludin levels and increases the endothelial permeability through the induction of VEGF production in retinal endothelial cells.
Data show that tight junction protein 1 (TJP1) suppressed expression of the catalytically proteasome subunits LMP7 (show PSMB8 ELISA Kits) and LMP2 (show PSMB9 ELISA Kits), decreased proteasome activity, and enhanced proteasome inhibitor sensitivity in vitro and in vivo through suppression of EGFR (show EGFR ELISA Kits)/JAK1 (show JAK1 ELISA Kits)/STAT3 (show STAT3 ELISA Kits) signaling.
ZO-1 highly expresses in cell-cell junctions and is related to odontoblast differentiation, which may contribute to dental pulp repair or even the formation of an odontoblast layer.
this study shows that the expression and the immunoreactivity of ZO-1 is decreased in the nasal epithelium of patients with allergic rhinitis
The frequency of alleles and genotypes of rs2291166 gene polymorphism TJP1 was determined in the Mexico Mestizos population. The ancestral allele was the most prevalent. The conformational effect of this amino acid change was performed in silico.
Cx43 (show GJA1 ELISA Kits) tethers the F-actin cytoskeleton through a ZO-1 linker and supports cell spreading and exploration during locomotion in cerebral endothelial cells.
Expression of Podocalyxin (show PODXL ELISA Kits), which positively regulates the formation of microvilli and the apical membrane, is repressed in embryoid bodies lacking both ZO-1 and ZO-2 (show TJP2 ELISA Kits) and this correlates with an aberrant submembranous localization of Ezrin (show EZR ELISA Kits).
Zonula occludens-1, occludin (show OCLN ELISA Kits) and E-cadherin (show CDH1 ELISA Kits) expression and organization in salivary glands
Tjp1 expression was decreased in glomerular diseases in human and animal models, our results indicate that the suppression of Tjp1 could directly aggravate glomerular disorders, highlights Tjp1 as a potential therapeutic target.
Arecoline increases the production of TNF-alpha (show TNF ELISA Kits) and induces protein redistribution of ZO-1.
Vcl (show VCL ELISA Kits) plays a crucial role in stabilizing gap junctions and myocyte integrity through direct interactions with ZO-1 and stabilization of CX43 (show GJA1 ELISA Kits).
Activation of RhoA (show RHOA ELISA Kits)/ROCK1 (show ROCK1 ELISA Kits) by high glucose in diabetic nephropathy disrupts the expression and translocation of occludin (show OCLN ELISA Kits)/ZO-1, which can be corrected by simvastatin.
Vascular endothelial tight junctions and barrier function are disrupted by 15(S)-hydroxyeicosatetraenoic acid partly via protein kinase C epsilon (show PRKCE ELISA Kits)-mediated zona occludens-1 phosphorylation at threonine 770/772.
The JAM-A (show F11R ELISA Kits) and ZO-1 genes were highly expressed in all the tested tissues.
cyclic strain modulates both the expression and phosphorylation state of occludin (show OCLN ELISA Kits) and ZO-1 in vascular endothelial cells, with putative consequences for endothelial tight junction assembly and barrier integrity
ZO-1 and occludin (show OCLN ELISA Kits) are expressed in oocytes and preimplantation embryos, and that ZO-1alpha+ is transcribed by zygotic gene activation and translated from early blastocysts with prominent increase of occludin (show OCLN ELISA Kits) at the blastocyst stage.
This gene encodes a protein located on a cytoplasmic membrane surface of intercellular tight junctions. The encoded protein may be involved in signal transduction at cell-cell junctions. Two transcript variants encoding distinct isoforms have been identified for this gene.
tight junction protein ZO-1
, zona occludens 1
, zona occludens protein 1
, zonula occludens 1 protein
, zonula occludens protein 1
, tight junction protein 1 (zona occludens 1)
, zonula occludens 1