Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all species
Show all synonyms
Select your species
The risk of coronary disease and ischemic stroke associated with multiple polymorphisms and haplotypes of MADD and FOLH1 in Han Chinese patients are reported in association with alcohol consumption.
miR (show MLXIP ELISA Kits)-3151 silencing by DNA methylation (show HELLS ELISA Kits) protected chronic lymphocytic leukemia cells from apoptosis by over-expression of its direct targets MADD (show ETFA ELISA Kits) and PIK3R2, constitutive activation of MEK (show MAP2K1 ELISA Kits)/ERK (show EPHB2 ELISA Kits) and PI3K (show PIK3CA ELISA Kits)/AKT (show AKT1 ELISA Kits) signaling , and over-expression of MCL1 (show MCL1 ELISA Kits).
Taken together, our data reveal that PTEN can convey the death signal by preventing MADD (show ETFA ELISA Kits) phosphorylation by Akt (show AKT1 ELISA Kits).
These results suggest that MADD (show ETFA ELISA Kits) may be a potential therapeutic target for lung adenocarcinoma therapy involving the TRAIL-induced apoptosis pathway
MADD (show ETFA ELISA Kits) knockdown resulted in enhanced spontaneous apoptosis in human breast cancer cell lines
We analyzed DENN/MADD/IG20 (DMI), the complex of four splice variants in Alzheimer's disease.
SNP rs2290149, located in a genetic cluster of MYBPC3 (show MYBPC3 ELISA Kits) and MADD (show ETFA ELISA Kits) gene, was found to be associated with diastolic heart failure.
Data show that ehe expression of MAPK (show MAPK1 ELISA Kits)-activating death domain protein (MADD (show ETFA ELISA Kits)) increases obviously in lung adenocarcinoma, and MADD (show ETFA ELISA Kits) can promote survival of lung adenocarcinoma cells by inhibiting apoptosis.
The SNP in ADCY5 (show ADCY5 ELISA Kits) is implicated in defective proinsulin (show INS ELISA Kits)-to-insulin (show INS ELISA Kits) conversion and previous findings on the role of a genetic variant in MADD (show ETFA ELISA Kits) on proinsulin (show INS ELISA Kits)-to-insulin (show INS ELISA Kits) conversion, were confirmed.
Data show that SNPs from MADD (show ETFA ELISA Kits), PROX1 (show PROX1 ELISA Kits), and SLC30A8 (show SLC30A8 ELISA Kits) were associated with type 2 diabetes.
These findings indicated that IG20/MADD plays a critical role in glucose-induced insulin (show INS ELISA Kits) release from beta-cells and that its functional disruption can cause type 2 diabetes.
role of Rab3 GEP in regulating neurotransmitter release in autapses of mouse hippocampal neurons in culture
DENN has anti-apoptotic and cell survival roles in tumor cells
Tumor necrosis factor alpha (TNF-alpha) is a signaling molecule that interacts with one of two receptors on cells targeted for apoptosis. The apoptotic signal is transduced inside these cells by cytoplasmic adaptor proteins. The protein encoded by this gene is a death domain-containing adaptor protein that interacts with the death domain of TNF-alpha receptor 1 to activate mitogen-activated protein kinase (MAPK) and propagate the apoptotic signal. It is membrane-bound and expressed at a higher level in neoplastic cells than in normal cells. Several transcript variants encoding different isoforms have been described for this gene.
MAP-kinase activating death domain
, MAP kinase-activating death domain protein
, MAP kinase-activating death domain protein-like
, Rab3 GDP/GTP exchange factor
, differentially expressed in normal and neoplastic cells
, insulinoma glucagonoma clone 20
, Rab3 GDP/GTP exchange protein
, Rab3 GEP
, insulinoma-glucagonoma protein 20
, rab3 GDP/GTP exchange factor