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Browse our CD51 Proteins (ITGAV)

Full name:
Integrin alpha V Proteins (ITGAV)
On www.antibodies-online.com are 13 Integrin alpha V (ITGAV) Proteins from 4 different suppliers available. Additionally we are shipping CD51 Antibodies (388) and CD51 Kits (11) and many more products for this protein. A total of 417 CD51 products are currently listed.
Synonyms:
1110004F14Rik, 2610028E01Rik, Cd51, D430040G12Rik, MSK8, VNRA, VTNR
list all proteins Gene Name GeneID UniProt
ITGAV 16410 P43406
ITGAV 3685 P06756
Rat ITGAV ITGAV 296456  

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CD51 Proteins (ITGAV) by Origin

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Top referenced CD51 Proteins

  1. Human CD51 Protein expressed in Wheat germ - ABIN2866314 : Ahn, Mohamedali, Anand, Cheruku, Birch, Sowmya, Cantor, Ranganathan, Inglis, Frank, Agrez, Nice, Baker: Characterization of the interaction between heterodimeric ?v?6 integrin and urokinase plasminogen activator receptor (uPAR) using functional proteomics. in Journal of proteome research 2014 (PubMed)

More Proteins for CD51 Interaction Partners

Mouse (Murine) Integrin alpha V (ITGAV) interaction partners

  1. Suggest that alphavbeta3 integrin plays an important role in coordinating hepatocyte division during liver regeneration after partial hepatectomy via crosstalk with fibrin ECM (show MMRN1 Proteins).

  2. Integrins alphavbeta6 and alphavbeta8 were expressed in non-overlapping patterns by keratinocytes and maintained the epidermal residence of Langerhans cells and tissue resident memory T cells by activating latent TGF-beta (show TGFB1 Proteins).

  3. This work identifies a previously unrecognized role for alphav and the autophagy components LC3 and atg5 in regulating TLR signalling and B-cell immunity.

  4. These data support the hypothesis that IL-1beta (show IL1B Proteins) was initially induced by hyperoxia; alphavbeta6 subsequently interacted with and activated TGF-beta1 (show TGFB1 Proteins).

  5. Gdf-5 (show GDF5 Proteins) induced the expression of the alpha5 sub-unit, while Bmp-7 (show BMP7 Proteins) induced the expression of the alphaV sub-unit.

  6. These results suggest that phloretin was an inhibitor of actin podosomes and sealing zone, disrupting alpha5beta3 integrin-c-Src-Pyk2/Syk signaling pathway for the regulation of actin cytoskeletal organization in osteoclasts.

  7. TN-C (show TNC Proteins) may enhance inflammatory responses by accelerating macrophage migration and synthesis of proinflammatory/profibrotic cytokines via integrin alphaVbeta3/FAK (show PTK2 Proteins)-Src (show SRC Proteins)/NF-kappaB (show NFKB1 Proteins), resulting in increased fibrosis.

  8. Lung histology revealed aberrant elastin (show ELN Proteins) production and impaired lung septation in oxygen-exposed lungs, while tropoelastin (show ELN Proteins), integrin alphav, fibulin-1 (show FBLN1 Proteins), fibulin-2 (show FBLN2 Proteins) and fibulin-4 (show FBLN4 Proteins) gene expression were elevated.

  9. Knock-in mice expressing a CCN1 (show CCNA2 Proteins) mutant that is unable to bind alphavbeta5/alphavbeta3 were impaired in ductular reaction. CCN1 (show CCNA2 Proteins), acting through its alphav beta3/alphav beta5 binding site, is critical for survival after bile duct ligation.

  10. These results suggest that integrin alphavbeta3 mediates the synergetic regulation of Cbfa1 (show RUNX2 Proteins) transcription activity by gravity and IGF-1 (show IGF1 Proteins) via PI3K signaling.

Human Integrin alpha V (ITGAV) interaction partners

  1. Thus, the alphaV integrin subunit is important for varicella-zoster virus gB/gH-gL-mediated viral membrane fusion and infection.

  2. The blockage of alphavbeta3 integrin inhibited the FAK (show PTK2 Proteins)-Src (show SRC Proteins) association and VEGFR (show KDR Proteins) activation, thus reducing tubulogenesis.

  3. The results implied that these five single nucleotide polymorphisms in the integrin alphavbeta3 gene were not associated with hemorrhagic fever with renal syndrome susceptibility or severity in Han Chinese individuals in Hubei Province.

  4. Gastric cancer patients who were both alphavbeta6 and MMP-9 (show MMP9 Proteins) positive had a shorter overall survival.

  5. The results of this study demonstrate that molecular dynamics of alphav integrin-GFP can be imaged in lung metastasis, which will allow further understanding of the role of alphav integrin in this process.

  6. Periostin (show POSTN Proteins) expression in human periodontal ligament fibroblasts promotes the migration of human mesenchymal stem cells through the alphavbeta3 integrin/FAK (show PTK2 Proteins)/PI3K (show PIK3CA Proteins)/Akt (show AKT1 Proteins) pathway in vitro.

  7. Results showed that CD51 expression in pancreatic cancer stroma is associated with enhanced tumor malignancy.

  8. endothelial VEGFR-2 appeared to be slightly superior to endothelial alpha v ss 3 for differentiating benign from cancerous lesions.

  9. PDI-mediated disulfide bond exchange plays a pivotal role in the post-ligation phase of alphaIIbbeta3-mediated adhesion to fibrinogen, while this step in alphavbeta3-mediated adhesion is independent of disulfide exchange

  10. Identify integrin alphavbeta3 as a receptor ofNC1 domain of collagen XIX. NC1(XIX) inhibits the FAK (show PTK2 Proteins)/PI3K (show PIK3CA Proteins)/Akt (show AKT1 Proteins)/mTOR (show FRAP1 Proteins) pathway, by decreasing the phosphorylation and activity of the major proteins involved in this pathway.

Pig (Porcine) Integrin alpha V (ITGAV) interaction partners

  1. The observed effects of shear stress on integrin alpha(v)beta(3) and p38 MAPK (show MAPK14 Proteins) activation, as well as on FGF-2 (show FGF2 Proteins) release could be mimicked by application of pancreatic elastase to static endothelial cells.

  2. Inhibition of integrin alphavbeta3 prevents urokinase plasminogen (show PLG Proteins) activator-mediated impairment of cerebrovasodilation after cerebral hypoxia/ischemia.

Cow (Bovine) Integrin alpha V (ITGAV) interaction partners

  1. Flow induced alpha2beta1 activation in cells on collagen, but not on fibronectin or fibrinogen. Conversely, alpha5beta1 and alphavbeta3 are activated on fibronectin and fibrinogen, but not collagen.

  2. specific substitutions show that the stable binding between foot-and-mouth disease virus VP1 and integrin alphavbeta6 is dependent on a helical structure and, specifically, two leucine residues at positions +1 and RGD +4 from the RGD motif.

  3. These results demonstrate the critical role of the RhoA (show RHOA Proteins)/alphavbeta5 integrin pathway in mediating Pseudomonas aeruginosa-induced lung vascular permeability.

CD51 (ITGAV) Protein Profile

Protein Summary

ITAGV encodes integrin alpha chain V. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The I-domain containing integrin alpha V undergoes post-translational cleavage to yield disulfide-linked heavy and light chains, that combine with multiple integrin beta chains to form different integrins. Among the known associating beta chains (beta chains 1,3,5,6, and 8\; 'ITGB1', 'ITGB3', 'ITGB5', 'ITGB6', and 'ITGB8'), each can interact with extracellular matrix ligands\; the alpha V beta 3 integrin, perhaps the most studied of these, is referred to as the Vitronectin receptor (VNR). In addition to adhesion, many integrins are known to facilitate signal transduction. Alternative splicing results in multiple transcript variants.

Alternative names and synonyms associated with CD51 (ITGAV)

  • integrin, alpha V (ITGAV)
  • integrin alpha V (Itgav)
  • integrin, alpha V (Itgav)
  • integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) (ITGAV)
  • 1110004F14Rik protein
  • 2610028E01Rik protein
  • Cd51 protein
  • D430040G12Rik protein
  • MSK8 protein
  • VNRA protein
  • VTNR protein

Protein level used designations for Integrin alpha V Proteins (ITGAV)

integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) , alphav integrin , integrin alpha V , integrin alpha-V , vitronectin receptor alpha polypeptide (VNRA) , vitronectin receptor subunit alpha , antigen identified by monoclonal antibody L230 , integrin alphaVbeta3 , Dnmt3l-ps1 pseudogene , alphaV integrin , integrin alpha v , vitronectin receptor alpha subunit , integrin alpha V subunit

GENE ID SPECIES
100068706 Equus caballus
443143 Ovis aries
16410 Mus musculus
3685 Homo sapiens
296456 Rattus norvegicus
488437 Canis lupus familiaris
397285 Sus scrofa
396420 Gallus gallus
281875 Bos taurus
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