Browse our Laminin alpha 5 Proteins (LAMA5)

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Laminin, alpha 5 Proteins (LAMA5)
On are 4 Laminin, alpha 5 (LAMA5) Proteins from 3 different suppliers available. Additionally we are shipping Laminin alpha 5 Antibodies (56) and Laminin alpha 5 Kits (17) and many more products for this protein. A total of 83 Laminin alpha 5 products are currently listed.
AA408760, AA408762, AI853660, cb402, im:7138247, laminin-511, mKIAA0533, sb:cb402, wu:fb81a10, [a]5
list all proteins Gene Name GeneID UniProt
LAMA5 3911 O15230
LAMA5 16776 Q61001
Rat LAMA5 LAMA5 140433  

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Laminin alpha 5 Proteins (LAMA5) by Origin

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Zebrafish Laminin, alpha 5 (LAMA5) interaction partners

Human Laminin, alpha 5 (LAMA5) interaction partners

  1. Both in cell lines and in mouse model, the extracellular matrix receptors including the integrin ( ITGA3 (show ITGA3 Proteins) and ITGA2B), collagen ( COL5A1), and laminin ( LAMA5) were significantly inhibited by curcumin at messenger RNA and protein levels.

  2. The Laminin-511 consists of alpha5, beta1, and gamma1 chains, of which three laminin globular domains of the alpha5 chain (alpha5/LG1-3) and a Glu (show DCTN1 Proteins) residue in the C-terminal tail of chain gamma1 (gamma1-Glu1607) are required for binding to integrins.

  3. The association of LAMA5 rs4925386 alleles with both inter-individual differences in height and in longevity suggests that laminins may be among the factors linking stature and cancer susceptibility.

  4. disruption of the LAMA5 gene dramatically reduced hPSC self-renewal and increased apoptosis without affecting the expression of pluripotency markers.

  5. Gal-1 (show LGALS1 Proteins) decreased the expression of collagen genes COL3A1 (show COL3A1 Proteins) and COL5A1 but increased the expression of fibronectin (show FN1 Proteins) and laminin 5.

  6. Lutheran (Lu), also known as basal cell adhesion molecule (B-CAM (show BCAM Proteins)), competes with integrins for binding to laminin alpha5, a subunit of LM-511, a major component of basement membranes.

  7. mechanistic role of laminin-511 in tissue homeostasis

  8. Polymorphisms in LN5 were associated with a reduced level of hemoglobin and neutropenia in non-small cell lung cancer.

  9. PDGF (show PDGFA Proteins)-BB is not superior to laminin as a potential marker of advanced CP.

  10. Data indicate that the function-blocking antibody against Lu/B-CAM (show BCAM Proteins) should be useful for not only investigating cell adhesion to laminin alpha5 but also for developing drugs to inhibit sickle cell vaso-occlusion.

Mouse (Murine) Laminin, alpha 5 (LAMA5) interaction partners

  1. The authors show that the integral endothelial basement membrane component, laminin 511 (laminin alpha5), is central to shear detection and mechanotransduction and its elimination at this site results in ablation of dilation in response to increased shear stress.

  2. According to the results, it seems that maternal nicotine exposure may induce abnormal laminin alpha 5 expression which may cause defects in kidney function during life time.

  3. Data suggest that the proper expression of laminin-332 (Lamb3 (show LAMB3 Proteins)) and laminin-511 (lama5) may regulate appropriate hair morphogenesis.

  4. Lutheran (Lu), also known as basal cell adhesion molecule (B-CAM (show BCAM Proteins)), competes with integrins for binding to laminin alpha5, a subunit of LM-511, a major component of basement membranes.

  5. Laminin alpha 5 (Lama5) mRNA expressions in the lung of newborn in the nicotine treated Exp D1 decreased by 0.63 fold.

  6. mechanistic role of laminin-511 in tissue homeostasis

  7. crystal structure of laminin alpha5LN-LE1-2 fragment shows the LN domain is a beta (show SUCLA2 Proteins)-jelly roll with several elaborate insertions; surface loop is required for stable ternary association with the beta- and gamma-short arms in the laminin network

  8. Data provides support for a primary role of laminin-511 and integrin beta-1 (show ITGB1 Proteins) promoting hair follicle epithelial downgrowth without affecting dermal primary cilia and Shh (show SHH Proteins) target gene induction.

  9. Downregulation of laminin-511 is important for hair regression.

  10. several peptides of Laminin alpha 5 had cell attachment activity and the ability to promote neurite outgrowth.

Laminin alpha 5 (LAMA5) Protein Profile

Protein Summary

Components of the extracellular matrix exert myriad effects on tissues throughout the body. In particular, the laminins, a family of heterotrimeric extracellular glycoproteins, affect tissue development and integrity in such diverse organs as the kidney, lung, skin, and nervous system. It is thought that laminins mediate the attachment, migration, and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Laminins function as heterotrimeric complexes of alpha, beta, and gamma chains, with each chain type representing a different subfamily of proteins. The protein encoded by this gene belongs to the alpha subfamily of laminin chains and is a major component of basement membranes. Two transcript variants encoding different isoforms have been found for this gene, but the full-length nature of one of them has not been determined.

Alternative names and synonyms associated with Laminin alpha 5 (LAMA5)

  • laminin, alpha 5 (LAMA5)
  • laminin, alpha 5 (lama5)
  • laminin, alpha 5 (Lama5)
  • AA408760 protein
  • AA408762 protein
  • AI853660 protein
  • cb402 protein
  • im:7138247 protein
  • laminin-511 protein
  • mKIAA0533 protein
  • sb:cb402 protein
  • wu:fb81a10 protein
  • [a]5 protein

Protein level used designations for Laminin, alpha 5 Proteins (LAMA5)

fra , fransen , laminin subunit alpha-5 , unm m538 , laminin, alpha 5 , laminin subunit alpha-5-like , laminin alpha-5 chain , laminin-10 subunit alpha , laminin-11 subunit alpha , laminin-15 subunit alpha

100058057 Equus caballus
321243 Danio rerio
428148 Gallus gallus
100145762 Xenopus (Silurana) tropicalis
100430603 Macaca mulatta
100552852 Anolis carolinensis
3911 Homo sapiens
16776 Mus musculus
140433 Rattus norvegicus
442954 Canis lupus familiaris
506751 Bos taurus
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