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Browse our Aurora Kinase B Proteins (AURKB)

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Aurora Kinase B Proteins (AURKB)
On are 19 Aurora Kinase B (AURKB) Proteins from 8 different suppliers available. Additionally we are shipping Aurora Kinase B Antibodies (210) and Aurora Kinase B Kits (10) and many more products for this protein. A total of 249 Aurora Kinase B products are currently listed.
Aik2, AIM-1, Aim1, AIRK2, AL022959, ARK-2, Ark2, Aur B, aurB, aurkb, aurkb-sv1, aurkb-sv2, Aurora-B, aurora B, CG6620, CHUNP6896, DmAIRK2, DmAurB, DmAuroraB, Dmel\\CG6620, fa09g06, Ial, IAL1, IKK2, IPL1, PPP1R48, STK-1, Stk5, Stk12, stka, wu:fa09g06, XAIRK2
list all proteins Gene Name GeneID UniProt
AURKB 9212 Q96GD4
AURKB 20877 O70126
AURKB 114592 O55099

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Aurora Kinase B Proteins (AURKB) by Origin

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Top referenced Aurora Kinase B Proteins

  1. Human Aurora Kinase B Protein expressed in Escherichia coli (E. coli) - ABIN668044 : Chen, Jin, Tahir, Zhang, Liu, Sarthy, McGonigal, Liu, Rosenberg, Ng: Survivin enhances Aurora-B kinase activity and localizes Aurora-B in human cells. in The Journal of biological chemistry 2002 (PubMed)
    Show all 2 references for ABIN668044

More Proteins for Aurora Kinase B Interaction Partners

Fruit Fly (Drosophila melanogaster) Aurora Kinase B (AURKB) interaction partners

  1. Aurora A (show AURKA Proteins) and B kinases directly phosphorylate Lgl to promote its mitotic relocalization.

  2. Regulation of Polo by Aurora B and Map205 is required for cytokinesis.

  3. We propose that mutual inhibitions between Aurora B a (show CDK1 Proteins)nd Cyclin B regulate the duration of abscission and thereby the number of sister cells in each cyst.

  4. Aurora B kinase activity is not required during contractile ring ingression, providing insight into the mechanism of cytokinesis.

  5. Aurora B interacts with and requires the Cdc37 (show CDC37 Proteins)/Hsp90 (show HSP90 Proteins) complex for its stability.

  6. INCENP (show INCENP Proteins) binds to the cohesion protector protein (show PRDX2 Proteins) MEI-S332, which is also an excellent in vitro substrate for Aurora B kinase.

Human Aurora Kinase B (AURKB) interaction partners

  1. Aurora kinases are important KRAS targets in lung cancer.

  2. Aurora A (show AURKA Proteins) and B inhibition had a significant antitumor effect against TNBC, and this antitumor effect was maximized by the combination of selumetinib with Aurora A (show AURKA Proteins) and B inhibition.

  3. Clk1 (show CDK11B Proteins), Clk2 (show CLK2 Proteins) and Clk4 (show CLK4 Proteins) prevent chromatin breakage by regulating the Aurora B-dependent abscission checkpoint.

  4. Combined treatment with aurora kinase (show AURKA Proteins) inhibitor SNS (show SCN10A Proteins)-314and quercetin-hyaluronic acid hydrogel results in synergistic cytotoxic effects in papillary and medullary thyroid carcinoma cells.

  5. NudC is co-localized with Aurora B at the midbody and co-immunoprecipitated with Aurora B in mitosis. results suggest that that dynamic phosphorylation of NudC by Aurora B regulates cytokinesis.

  6. Aurora B and CDK1 (show CDK1 Proteins) temporally regulate the binding affinity of EB2 (show MAPRE2 Proteins) for microtubules, thereby ensuring kinetochore microtubule dynamics, proper mitotic progression and genome stability.

  7. the Aurora B-PLK1 signaling at the kinetochore orchestrates MCAK (show KIF2C Proteins) activity, which is essential for timely correction of aberrant kinetochore attachment to ensure accurate chromosome segregation during mitosis.

  8. PC4 (show IFRD1 Proteins) associates with Aurora A (show AURKA Proteins) and Aurora B and undergoes phosphorylation, following which PC4 (show IFRD1 Proteins) activates both Aurora A (show AURKA Proteins) and B to sustain optimal kinase activity to maintain the phosphorylation gradient for the proper functioning of the mitotic machinery.

  9. HP1 (show DEFA1 Proteins) binding to the chromosomal passenger complex becomes particularly important when Aurora B phosphorylates kinetochore targets to eliminate erroneous microtubule attachments

  10. UBASH3B (show STS1 Proteins) is necessary for the timing and fidelity of chromosome segregation in human cells

Mouse (Murine) Aurora Kinase B (AURKB) interaction partners

  1. Overexpression of Aurora B (show AURKC Proteins) also results in a reduced DNA damage response and decreased levels of the p53 (show TP53 Proteins) target p21(Cip1 (show CDKN1A Proteins)) in vitro and in vivo.

  2. Chromsome stability is on of the tumor-suppressive functions of ARF as well as regulation of Aurora B (show AURKC Proteins) expression in tumors.

  3. Using this mutant we show for the first time that AURKC has functions that do not overlap with AURKB. These functions include regulating localized CPC activity and regulating chromosome alignment and K-MT attachments at metaphase of meiosis I (Met I).

  4. reduced accumulation of Aurora B (show AURKC Proteins) at the inner centromere region in cells lacking Pds5B (show PDS5B Proteins) impairs its error correction function, promoting chromosome mis (show AMH Proteins)-segregation and aneuploidy

  5. Aurora B (show AURKC Proteins) and Ring1B (show RNF2 Proteins) co-occupy active promoters in resting lymphocytes.

  6. FBXL2 (show FBXL2 Proteins) mediates Aurora B (show AURKC Proteins) ubiquitination and degradation within the midbody, which is sufficient to induce mitotic arrest and apoptosis.

  7. Inhibitions of Aurora B (show AURKC Proteins) and Cyclin-dependent kinase 1 (show CDK1 Proteins) activity in vertebrate cells also have opposite effects on the timing of abscission.

  8. Aurora B (show AURKC Proteins) represses p21(Cip1 (show CDKN1A Proteins)), preventing delayed DNA replication, Cdk (show CDK4 Proteins) inhibition and premature mitotic exit.

  9. Calmodulin (show Calm2 Proteins) protects Aurora B (show AURKC Proteins) on the midbody to regulate the fidelity of cytokinesis.

  10. the BRAF (show BRAF Proteins)/ERK (show EPHB2 Proteins) axis controls Aurora B (show AURKC Proteins) expression at the transcriptional level, likely through the transcription factor FOXM1 (show FOXM1 Proteins).

Cow (Bovine) Aurora Kinase B (AURKB) interaction partners

  1. Alterations in PGRMC1 (show PGRMC1 Proteins) and/or AURKB localization account in part for the increased aneuploidy and low development competence of oocytes from ovaries with reduced antral follicle counts.

  2. AURKB associated with metaphase chromosomes.

Zebrafish Aurora Kinase B (AURKB) interaction partners

  1. Aurora B kinase is essential for furrow induction and maturation in the zebrafish embryo.

Aurora Kinase B (AURKB) Protein Profile

Protein Summary

This gene encodes a member of the aurora kinase subfamily of serine/threonine kinases. The genes encoding the other two members of this subfamily are located on chromosomes 19 and 20. These kinases participate in the regulation of segregation of chromosomes during mitosis and meiosis through association with microtubules. A pseudogene of this gene is located on chromosome 8. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with Aurora Kinase B (AURKB)

  • IplI-aurora-like kinase (ial)
  • aurora kinase B (aurkb)
  • aurora kinase B (AURKB)
  • aurora kinase B (Aurkb)
  • inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (Ikbkb)
  • Aik2 protein
  • AIM-1 protein
  • Aim1 protein
  • AIRK2 protein
  • AL022959 protein
  • ARK-2 protein
  • Ark2 protein
  • Aur B protein
  • aurB protein
  • aurkb protein
  • aurkb-sv1 protein
  • aurkb-sv2 protein
  • Aurora-B protein
  • aurora B protein
  • CG6620 protein
  • CHUNP6896 protein
  • DmAIRK2 protein
  • DmAurB protein
  • DmAuroraB protein
  • Dmel\\CG6620 protein
  • fa09g06 protein
  • Ial protein
  • IAL1 protein
  • IKK2 protein
  • IPL1 protein
  • PPP1R48 protein
  • STK-1 protein
  • Stk5 protein
  • Stk12 protein
  • stka protein
  • wu:fa09g06 protein
  • XAIRK2 protein

Protein level used designations for Aurora Kinase B Proteins (AURKB)

AURORA-like , CG6620-PA , DmAuroraB , aurora , aurora B , aurora B kinase , aurora-B , auroraB , dAurora B , ial-PA , aurora/IPL1-related kinase 2 , serine/threonine-protein kinase 12 , serine/threonine-protein kinase aurora-B , xAurora-B , aurora kinase B , serine/threonine-protein kinase 12-like , ARK-2 , STK-1 , aurora 1 , aurora kinase B-Sv1 , aurora kinase B-Sv2 , aurora- and Ipl1-like midbody-associated protein 1 , aurora-1 , aurora-related kinase 2 , protein phosphatase 1, regulatory subunit 48 , serine/threonine kinase 12 , serine/threonine-protein kinase 5 , aurora- and IPL1-like midbody-associated protein 1 , serine/threonine kinase 5 , AIM-1 , Serine/threonine-protein kinase 12 , aurB , cei , cellular island , serine/threonine kinase a , I-kappa-B kinase 2 , I-kappa-B-kinase beta , IKK-B , IKK-beta , NFKBIKB , inhibitor of kappaB kinase beta , inhibitor of nuclear factor kappa B kinase beta subunit , inhibitor of nuclear factor kappa-B kinase subunit beta , nuclear factor NF-kappa-B inhibitor kinase beta

34504 Drosophila melanogaster
549613 Xenopus (Silurana) tropicalis
100301584 Oryzias latipes
100399490 Callithrix jacchus
100448258 Pongo abelii
100528532 Ictalurus punctatus
9212 Homo sapiens
20877 Mus musculus
114592 Rattus norvegicus
479492 Canis lupus familiaris
396955 Sus scrofa
360192 Bos taurus
455095 Pan troglodytes
791894 Danio rerio
84351 Rattus norvegicus
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