Browse our Aurora Kinase B Proteins (AURKB)

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Aurora Kinase B Proteins (AURKB)
On are 19 Aurora Kinase B (AURKB) Proteins from 8 different suppliers available. Additionally we are shipping Aurora Kinase B Antibodies (292) and Aurora Kinase B Kits (11) and many more products for this protein. A total of 334 Aurora Kinase B products are currently listed.
Aik2, AIM-1, Aim1, AIRK2, AL022959, ARK-2, Ark2, Aur B, aurB, aurkb, aurkb-sv1, aurkb-sv2, Aurora-B, aurora B, CG6620, CHUNP6896, DmAIRK2, DmAurB, DmAuroraB, Dmel\\CG6620, fa09g06, Ial, IAL1, IKK2, IPL1, PPP1R48, STK-1, Stk5, Stk12, stka, wu:fa09g06, XAIRK2
list all proteins Gene Name GeneID UniProt
AURKB 9212 Q96GD4
AURKB 20877 O70126
AURKB 114592 O55099

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Aurora Kinase B Proteins (AURKB) by Origin

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Top referenced Aurora Kinase B Proteins

  1. Human Aurora Kinase B Protein expressed in Escherichia coli (E. coli) - ABIN668044 : Chen, Jin, Tahir, Zhang, Liu, Sarthy, McGonigal, Liu, Rosenberg, Ng: Survivin enhances Aurora-B kinase activity and localizes Aurora-B in human cells. in The Journal of biological chemistry 2002 (PubMed)
    Show all 2 references for 668044

More Proteins for Aurora Kinase B Interaction Partners

Fruit Fly (Drosophila melanogaster) Aurora Kinase B (AURKB) interaction partners

  1. Aurora A (show AURKA Proteins) and B kinases directly phosphorylate Lgl to promote its mitotic relocalization.

  2. Regulation of Polo by Aurora B and Map205 is required for cytokinesis.

  3. We propose that mutual inhibitions between Aurora B a (show CDK1 Proteins)nd Cyclin B regulate the duration of abscission and thereby the number of sister cells in each cyst.

  4. Aurora B kinase activity is not required during contractile ring ingression, providing insight into the mechanism of cytokinesis.

  5. Aurora B interacts with and requires the Cdc37 (show CDC37 Proteins)/Hsp90 (show HSP90 Proteins) complex for its stability.

  6. INCENP (show INCENP Proteins) binds to the cohesion protector protein (show PRDX2 Proteins) MEI-S332, which is also an excellent in vitro substrate for Aurora B kinase.

Human Aurora Kinase B (AURKB) interaction partners

  1. Aurora-C (show AURKC Proteins) interactions with members of the Chromosome Passenger Complex (CPC), Survivin (show BIRC5 Proteins) and Inner Centromere Protein (INCENP (show INCENP Proteins)) in reference to known Aurora-B interactions to understand the functional significance of Aurora-C (show AURKC Proteins) overexpression in human cancer cells, is reported.

  2. Aurora kinase (show AURKA Proteins) inhibitor danusertib negatively regulated AURKB/p70S6K (show RPS6KB1 Proteins)/RPL15 (show RPL15 Proteins) axis with the involvement of PI3K (show PIK3CA Proteins)/Akt (show AKT1 Proteins)/mTOR (show FRAP1 Proteins), AMPK (show PRKAA1 Proteins), and p38 MAPK (show MAPK14 Proteins) signaling pathways, leading to the induction of apoptosis and autophagy in human leukemia cells.

  3. The kinase activity of Aurora B on serine 31 of histone H3.3 (show H3F3A Proteins) was biochemically confirmed with nucleosomal substrates in vitro.

  4. in addition to its role in checkpoint signaling, MAD2 (show MAD2L1 Proteins) ensures chromosome stability through the regulation of AURORA B.

  5. Ska promotes Aurora B activity to limit its own microtubule and kinetochore association.

  6. partial co-localization of AKT3 (show AKT3 Proteins) with AURKB was observed during anaphase. Overall, this study suggests that AKT3 (show AKT3 Proteins) could repress the antiproliferative effects of AURKi, with a novel activity particularly suppressing the aneuploidy induction.

  7. Our study mechanistically explains a p53 (show TP53 Proteins)-independent mode of action of a chemical Aurora B inhibitor and suggests a potential triggering of antitumoral immune responses, following polyploidization of tumor cells, which might constrain recovery of aneuploid tumor cells.

  8. Our data demonstrate that the cytokinetic proteins epithelial cell transforming 2 and Aurora kinase B (AurkB) are localized to stress granules in human astrocytoma cells

  9. a resorcinol derivative, 5-methyl-4-(2-thiazolylazo) resorcinol (PTK66), a dual inhibitor of Aurora A (show AURKA Proteins) and Aurora B kinases. PTK66 is a surface binding non-ATP analogue inhibitor that shows a mixed pattern of inhibition against both of Aurora A (show AURKA Proteins) and B kinases

  10. overexpression of PAK1 (show PAK1 Proteins), NEK6 (show NEK6 Proteins), AURKA (show AURKA Proteins), and AURKB genes in patients with Colorectal adenomatous polyp and colorectal cancer in the Turkish population.

Mouse (Murine) Aurora Kinase B (AURKB) interaction partners

  1. Aurkb phosphorylates Oct4 (show POU5F1 Proteins)(S229) during G2/M phase, leading to the dissociation of Oct4 (show POU5F1 Proteins) from chromatin, whereas PP1 (show PPP1CC Proteins) binds Oct4 (show POU5F1 Proteins) and dephosphorylates Oct4 (show POU5F1 Proteins)(S229) during M/G1 transition, which resets Oct4 (show POU5F1 Proteins)-driven transcription for pluripotency and the cell cycle.

  2. Overexpression of Aurora B (show AURKC Proteins) also results in a reduced DNA damage response and decreased levels of the p53 (show TP53 Proteins) target p21(Cip1 (show CDKN1A Proteins)) in vitro and in vivo.

  3. Chromsome stability is on of the tumor-suppressive functions of ARF as well as regulation of Aurora B (show AURKC Proteins) expression in tumors.

  4. Using this mutant we show for the first time that AURKC has functions that do not overlap with AURKB. These functions include regulating localized CPC activity and regulating chromosome alignment and K-MT attachments at metaphase of meiosis I (Met I).

  5. reduced accumulation of Aurora B (show AURKC Proteins) at the inner centromere region in cells lacking Pds5B (show PDS5B Proteins) impairs its error correction function, promoting chromosome mis (show AMH Proteins)-segregation and aneuploidy

  6. Aurora B (show AURKC Proteins) and Ring1B (show RNF2 Proteins) co-occupy active promoters in resting lymphocytes.

  7. FBXL2 (show FBXL2 Proteins) mediates Aurora B (show AURKC Proteins) ubiquitination and degradation within the midbody, which is sufficient to induce mitotic arrest and apoptosis.

  8. Inhibitions of Aurora B (show AURKC Proteins) and Cyclin-dependent kinase 1 (show CDK1 Proteins) activity in vertebrate cells also have opposite effects on the timing of abscission.

  9. Aurora B (show AURKC Proteins) represses p21(Cip1 (show CDKN1A Proteins)), preventing delayed DNA replication, Cdk (show CDK4 Proteins) inhibition and premature mitotic exit.

  10. Calmodulin (show Calm2 Proteins) protects Aurora B (show AURKC Proteins) on the midbody to regulate the fidelity of cytokinesis.

Cow (Bovine) Aurora Kinase B (AURKB) interaction partners

  1. Alterations in PGRMC1 (show PGRMC1 Proteins) and/or AURKB localization account in part for the increased aneuploidy and low development competence of oocytes from ovaries with reduced antral follicle counts.

  2. AURKB associated with metaphase chromosomes.

Zebrafish Aurora Kinase B (AURKB) interaction partners

  1. Aurora B kinase is essential for furrow induction and maturation in the zebrafish embryo.

Aurora Kinase B (AURKB) Protein Profile

Protein Summary

This gene encodes a member of the aurora kinase subfamily of serine/threonine kinases. The genes encoding the other two members of this subfamily are located on chromosomes 19 and 20. These kinases participate in the regulation of segregation of chromosomes during mitosis and meiosis through association with microtubules. A pseudogene of this gene is located on chromosome 8. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with Aurora Kinase B (AURKB)

  • IplI-aurora-like kinase (ial)
  • aurora kinase B (aurkb)
  • aurora kinase B (AURKB)
  • aurora kinase B (Aurkb)
  • inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (Ikbkb)
  • Aik2 protein
  • AIM-1 protein
  • Aim1 protein
  • AIRK2 protein
  • AL022959 protein
  • ARK-2 protein
  • Ark2 protein
  • Aur B protein
  • aurB protein
  • aurkb protein
  • aurkb-sv1 protein
  • aurkb-sv2 protein
  • Aurora-B protein
  • aurora B protein
  • CG6620 protein
  • CHUNP6896 protein
  • DmAIRK2 protein
  • DmAurB protein
  • DmAuroraB protein
  • Dmel\\CG6620 protein
  • fa09g06 protein
  • Ial protein
  • IAL1 protein
  • IKK2 protein
  • IPL1 protein
  • PPP1R48 protein
  • STK-1 protein
  • Stk5 protein
  • Stk12 protein
  • stka protein
  • wu:fa09g06 protein
  • XAIRK2 protein

Protein level used designations for Aurora Kinase B Proteins (AURKB)

AURORA-like , CG6620-PA , DmAuroraB , aurora , aurora B , aurora B kinase , aurora-B , auroraB , dAurora B , ial-PA , aurora/IPL1-related kinase 2 , serine/threonine-protein kinase 12 , serine/threonine-protein kinase aurora-B , xAurora-B , aurora kinase B , serine/threonine-protein kinase 12-like , ARK-2 , STK-1 , aurora 1 , aurora kinase B-Sv1 , aurora kinase B-Sv2 , aurora- and Ipl1-like midbody-associated protein 1 , aurora-1 , aurora-related kinase 2 , protein phosphatase 1, regulatory subunit 48 , serine/threonine kinase 12 , serine/threonine-protein kinase 5 , aurora- and IPL1-like midbody-associated protein 1 , serine/threonine kinase 5 , AIM-1 , Serine/threonine-protein kinase 12 , aurB , cei , cellular island , serine/threonine kinase a , I-kappa-B kinase 2 , I-kappa-B-kinase beta , IKK-B , IKK-beta , NFKBIKB , inhibitor of kappaB kinase beta , inhibitor of nuclear factor kappa B kinase beta subunit , inhibitor of nuclear factor kappa-B kinase subunit beta , nuclear factor NF-kappa-B inhibitor kinase beta

34504 Drosophila melanogaster
549613 Xenopus (Silurana) tropicalis
100301584 Oryzias latipes
100399490 Callithrix jacchus
100448258 Pongo abelii
100528532 Ictalurus punctatus
9212 Homo sapiens
20877 Mus musculus
114592 Rattus norvegicus
479492 Canis lupus familiaris
396955 Sus scrofa
360192 Bos taurus
455095 Pan troglodytes
791894 Danio rerio
84351 Rattus norvegicus
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