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Browse our BMI1 Proteins (BMI1)

Full name:
BMI1 Polycomb Ring Finger Oncogene Proteins (BMI1)
On www.antibodies-online.com are 13 BMI1 Polycomb Ring Finger Oncogene (BMI1) Proteins from 7 different suppliers available. Additionally we are shipping BMI1 Antibodies (295) and BMI1 Kits (12) and many more products for this protein. A total of 331 BMI1 products are currently listed.
Synonyms:
AW546694, BMI-1, bmi1, FLVI2/BMI1, Pcgf4, psc1, RNF51, wu:fb17g03, wu:fd18f06
list all proteins Gene Name GeneID UniProt
BMI1 648 P35226
BMI1 12151 P25916
Rat BMI1 BMI1 307151  

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BMI1 Proteins (BMI1) by Origin

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More Proteins for BMI1 Interaction Partners

Zebrafish BMI1 Polycomb Ring Finger Oncogene (BMI1) interaction partners

  1. Bmi1 acts immediately downstream of CCAAT enhancer binding protein-alpha (show CEBPA Proteins) to regulate the survival and self-renewal of hematopoietic stem cells and contribute to the erythropoietic dysplasia.

Human BMI1 Polycomb Ring Finger Oncogene (BMI1) interaction partners

  1. human BMI-1 increases the proliferative potential of bronchial epithelial cells while retaining their mucociliary differentiation potential.

  2. Low BMI-1 expression Correlates with Pulmonary Squamous Cell Carcinoma.

  3. Results show that BMI1 and FSCN1 (show FSCN1 Proteins) are highly expressed in colorectal neoplasm and correlate with poor prognosis.

  4. Upregulation of bmi1 is associated with glioma progression.

  5. Results provide evidence that BMI1 play an important role in radioresistance of triple-negative breast cancer cells.

  6. Knockdown of Bmi-1 significantly inhibited the aggressive behavior of melanoma by reversing epithelial-mesenchymal transition-like changes via the PTEN/p-Akt (show AKT1 Proteins)/pNF-kappaB/MMP-2 (show MMP2 Proteins) pathway.

  7. BMI-1 plays a pivotal role in the progression of ovarian cancer, thus representing a novel target for antitumor therapy of ovarian cancer.

  8. miR203 exerts growthinhibiting effects in MM through the suppression of Bmi1 expression. In conclusion, the present study demonstrated that Bmi1 is a direct functional target of miR (show MLXIP Proteins)-203 in MM.

  9. Downregulation of BMI1 mRNA expression is associated with basal cell carcinoma.

  10. Knockdown of BMI-1 expression decreased the phosphorylation of H2AX, upregulated p16, and induced the radiosensitivity of esophageal cancer ECA109 and TE13 cells in vitro and significantly inhibited the growth and invasion of tumor cells. The mechanisms were found to be abrogation of cell cycle arrest at the G2/M stage and promotion of apoptosis.

Mouse (Murine) BMI1 Polycomb Ring Finger Oncogene (BMI1) interaction partners

  1. a full complement of Bmi-1 is required for the intestinal proliferative effects of GLP-2 in both the physiological and pathological setting

  2. Our work revealed that MOZ and BMI1 regulate HSCs in a synergistic manner by acting on distinct processes required to maintain HSCs.

  3. Bmi-1 played a critical role in the protection from acute tubular necrosis by maintaining mobilization of renal stem cells and would be a novel therapeutic target for preventing the progression of ATN

  4. Bmi1 deletion could substitute for Gata4 (show GATA4 Proteins) during iCM reprogramming. Thus, Bmi1 acts as a critical epigenetic barrier to iCM production. Bypassing this barrier simplifies iCM generation and increases yield, potentially streamlining iCM production for therapeutic purposes.

  5. Cardiac Bmi1 progenitor cells respond to cardiac injury, contributing to the generation of de novo cardiomyocytes in the adult mouse heart.

  6. Bmi1 is a potential driver oncogene (show RAB1A Proteins) of bladder cancer, and it may become a potential treatment target for human bladder cancer.

  7. High Bmi1 expression identifies a non-cardiomyocyte resident cardiac population that contributes to the main lineages of the heart in vitro and in vivo.

  8. Here we show that inactivation of BMI1 using specific siRNA slows and decreases the levels of adipocyte differentiation , but does not abolish it.

  9. These observations suggest a dynamic and developmentally regulated model of PRC1 (show PRC1 Proteins) occupancy at constitutive heterochromatin, and where BMI1 function in somatic cells is to stabilize the repetitive genome

  10. Hypoxia models showed the mechanism by which hypoxia promoted Twist1 (show TWIST1 Proteins) and Bmi1 expression and led to vasculogenic mimicry formation.

BMI1 Protein Profile

Protein Summary

Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones\; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2 (By similarity).

Alternative names and synonyms associated with BMI1

  • BMI1 polycomb ring finger oncogene (LOC100230513)
  • BMI1 polycomb ring finger oncogene (LOC100358360)
  • B lymphoma Mo-MLV insertion region 1a (bmi1a)
  • BMI1 polycomb ring finger oncogene (BMI1)
  • Bmi1 polycomb ring finger oncogene (Bmi1)
  • AW546694 protein
  • BMI-1 protein
  • bmi1 protein
  • FLVI2/BMI1 protein
  • Pcgf4 protein
  • psc1 protein
  • RNF51 protein
  • wu:fb17g03 protein
  • wu:fd18f06 protein

Protein level used designations for BMI1

BMI1 polycomb ring finger oncogene , B lymphoma Mo-MLV insertion region 1 homolog , polycomb complex protein BMI-1-A , polycomb group RING finger protein 4-A , polycomb group ring finger 4 , flvi-2/bmi-1 , murine leukemia viral (bmi-1) oncogene homolog , polycomb complex protein BMI-1 , polycomb group RING finger protein 4 , polycomb group protein Bmi1 , ring finger protein 51 , B lymphoma Mo-MLV insertion region 1 , B lymphoma Mo-MLV insertion region

GENE ID SPECIES
100230513 Taeniopygia guttata
100358360 Oryctolagus cuniculus
321505 Danio rerio
648 Homo sapiens
510666 Bos taurus
12151 Mus musculus
307151 Rattus norvegicus
487097 Canis lupus familiaris
554342 Felis catus
493647 Gallus gallus
100009347 Oryctolagus cuniculus
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