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Browse our BMI1 Proteins (BMI1)

Full name:
BMI1 Polycomb Ring Finger Oncogene Proteins (BMI1)
On www.antibodies-online.com are 11 BMI1 Polycomb Ring Finger Oncogene (BMI1) Proteins from 8 different suppliers available. Additionally we are shipping BMI1 Antibodies (235) and BMI1 Kits (8) and many more products for this protein. A total of 264 BMI1 products are currently listed.
Synonyms:
AW546694, BMI-1, bmi1, FLVI2/BMI1, Pcgf4, psc1, RNF51, wu:fb17g03, wu:fd18f06
list all proteins Gene Name GeneID UniProt
BMI1 648 P35226
BMI1 12151 P25916
Rat BMI1 BMI1 307151  

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BMI1 Proteins (BMI1) by Origin

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More Proteins for BMI1 Interaction Partners

Zebrafish BMI1 Polycomb Ring Finger Oncogene (BMI1) interaction partners

  1. Bmi1 acts immediately downstream of CCAAT enhancer binding protein-alpha (show CEBPA Proteins) to regulate the survival and self-renewal of hematopoietic stem cells and contribute to the erythropoietic dysplasia.

Human BMI1 Polycomb Ring Finger Oncogene (BMI1) interaction partners

  1. These data show that BMI1 regulates cell proliferation, apoptosis, and differentiation of human mesenchymal stem cells.

  2. Results provide functional and mechanistic links between Hes1 and Bmi-1/PTEN/Akt/GSK3beta signaling in the development and progression of colon cancer.

  3. BMI1 ubiquitinates histone H2A and gammaH2AX (show H2AFX Proteins), thereby facilitating the repair of double-stranded DNA breaks through stimulating homologous recombination and non-homologous end joining. [review]

  4. MKK3 (show MAP2K3 Proteins) overexpression upregulated the cyclin-dependent kinase (show CDK1 Proteins) inhibitors, p16 INK4A and p15 INK4B (show CDKN2B Proteins) in hepatocellular carcinoma cells was Bim1, was downregulated following MKK3 (show MAP2K3 Proteins) overexpression.

  5. Data show that increased polycomb (show CBX2 Proteins) repressive complex 2 EZH2 (show EZH2 Proteins) and/or polycomb (show CBX2 Proteins) repressive complex 1 BMI1 expression repress the expression of microRNA miR (show MLXIP Proteins)-200 family members.

  6. These results provide important insights into the role of Bmi-1 in the occurrence and development of nasopharyngeal carcinoma

  7. Bmi1 is a potential driver oncogene (show RAB1A Proteins) of bladder cancer, and it may become a potential treatment target for human bladder cancer.

  8. The polycomb complex proteins BMI1 and RING1A regulate the ubiquitination of chromatin associated proteins bound to promoters.

  9. Data show that polycomb (show CBX2 Proteins)-group proteins BMI1, PHC3 (show PHC3 Proteins), CBX6 (show CBX6 Proteins) and CBX7 (show CBX7 Proteins) expression was significantly increased during imatinib treatment.

  10. activated microRNA-494-targets Bmi1 and ADAM10 (show ADAM10 Proteins) by silibinin and ablates cancer stemness in head and neck squamous cell carcinomas

Mouse (Murine) BMI1 Polycomb Ring Finger Oncogene (BMI1) interaction partners

  1. Bmi1 is a potential driver oncogene (show RAB1A Proteins) of bladder cancer, and it may become a potential treatment target for human bladder cancer.

  2. High Bmi1 expression identifies a non-cardiomyocyte resident cardiac population that contributes to the main lineages of the heart in vitro and in vivo.

  3. Here we show that inactivation of BMI1 using specific siRNA slows and decreases the levels of adipocyte differentiation , but does not abolish it.

  4. These observations suggest a dynamic and developmentally regulated model of PRC1 (show PRC1 Proteins) occupancy at constitutive heterochromatin, and where BMI1 function in somatic cells is to stabilize the repetitive genome

  5. Hypoxia models showed the mechanism by which hypoxia promoted Twist1 (show TWIST1 Proteins) and Bmi1 expression and led to vasculogenic mimicry formation.

  6. Dysregulation of the Bmi-1/p16Ink4a pathway provokes an aging-associated decline of submandibular gland function.

  7. Bmi-1 overexpression conferred extensive self-renewal capacity upon adult bone-marrow-derived self-renewing erythroblasts, which normally have limited proliferative potential.

  8. Bmi1 limits dilated cardiomyopathy and heart failure by inhibiting cardiac senescence.

  9. Lgr6 (show LGR6 Proteins) and Bmi1 have roles in stem cells in the acral epithelium that participate in the long-term maintenance of sweat glands, ducts, and interadnexal epidermis, while Lgr5 (show LGR5 Proteins) has a role in rapid cycling and maintance of sweat glands only

  10. BMI1 expression in human hematopoietic stem and progenitor cells from patients with DBA (show RPS19 Proteins) is correlated with the expression of some ribosomal protein genes, suggesting that BMI1 deficiency may play a pathological role in DBA (show RPS19 Proteins) and other ribosomopathies.

BMI1 Protein Profile

Protein Summary

Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones\; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2 (By similarity).

Alternative names and synonyms associated with BMI1

  • BMI1 polycomb ring finger oncogene (LOC100230513)
  • BMI1 polycomb ring finger oncogene (LOC100358360)
  • B lymphoma Mo-MLV insertion region 1a (bmi1a)
  • BMI1 polycomb ring finger oncogene (BMI1)
  • Bmi1 polycomb ring finger oncogene (Bmi1)
  • AW546694 protein
  • BMI-1 protein
  • bmi1 protein
  • FLVI2/BMI1 protein
  • Pcgf4 protein
  • psc1 protein
  • RNF51 protein
  • wu:fb17g03 protein
  • wu:fd18f06 protein

Protein level used designations for BMI1

BMI1 polycomb ring finger oncogene , B lymphoma Mo-MLV insertion region 1 homolog , polycomb complex protein BMI-1-A , polycomb group RING finger protein 4-A , polycomb group ring finger 4 , flvi-2/bmi-1 , murine leukemia viral (bmi-1) oncogene homolog , polycomb complex protein BMI-1 , polycomb group RING finger protein 4 , polycomb group protein Bmi1 , ring finger protein 51 , B lymphoma Mo-MLV insertion region 1 , B lymphoma Mo-MLV insertion region

GENE ID SPECIES
100230513 Taeniopygia guttata
100358360 Oryctolagus cuniculus
321505 Danio rerio
648 Homo sapiens
510666 Bos taurus
12151 Mus musculus
307151 Rattus norvegicus
487097 Canis lupus familiaris
554342 Felis catus
493647 Gallus gallus
100009347 Oryctolagus cuniculus
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