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Browse our BMI1 Proteins (BMI1)

Full name:
BMI1 Polycomb Ring Finger Oncogene Proteins (BMI1)
On www.antibodies-online.com are 14 BMI1 Polycomb Ring Finger Oncogene (BMI1) Proteins from 8 different suppliers available. Additionally we are shipping BMI1 Antibodies (300) and BMI1 Kits (10) and many more products for this protein. A total of 334 BMI1 products are currently listed.
Synonyms:
AW546694, BMI-1, bmi1, FLVI2/BMI1, Pcgf4, psc1, RNF51, wu:fb17g03, wu:fd18f06
list all proteins Gene Name GeneID UniProt
BMI1 648 P35226
BMI1 12151 P25916
Rat BMI1 BMI1 307151  

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BMI1 Proteins (BMI1) by Origin

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More Proteins for BMI1 Interaction Partners

Zebrafish BMI1 Polycomb Ring Finger Oncogene (BMI1) interaction partners

  1. Bmi1 acts immediately downstream of CCAAT enhancer binding protein-alpha (show CEBPA Proteins) to regulate the survival and self-renewal of hematopoietic stem cells and contribute to the erythropoietic dysplasia.

Human BMI1 Polycomb Ring Finger Oncogene (BMI1) interaction partners

  1. Knockdown of BMI-1 expression decreased the phosphorylation of H2AX, upregulated p16, and induced the radiosensitivity of esophageal cancer ECA109 and TE13 cells in vitro and significantly inhibited the growth and invasion of tumor cells. The mechanisms were found to be abrogation of cell cycle arrest at the G2/M stage and promotion of apoptosis.

  2. Bmi-1 promotes the invasion and migration of colon cancer stem cells through the downregulation of E-cadherin (show CDH1 Proteins).

  3. High expression of BMI1 is associated with glioma chemoresistance.

  4. Long noncoding RNA uc.338 promotes HCC (show FAM126A Proteins) cell proliferation and induces cell cycle progression through association with BMI1. uc.338 also modulated the transcription of CDKN1A.

  5. Bmi-1 messenger RNA level was found much higher in salivary adenoid cystic carcinoma tissues than in the adjacent noncancerous salivary gland tissues

  6. results indicate that microRNA-200b is partially silenced by DNA hypermethylation and that it can repress tumor progression by directly targeting BMI1 in HCC (show FAM126A Proteins).

  7. Bmi-1 expression in colon cancer tissue is significantly higher than that in corresponding normal tissue.

  8. our work indicated that decreased SLC34A2 (show SLC34A2 Proteins) expression sensitized BCSCs to doxorubicin via SLC34A2 (show SLC34A2 Proteins)-Bmi1-ABCC5 (show ABCC5 Proteins) signaling and shed new light on understanding the mechanism of chemoresistance in BCSCs. This study not only bridges the missing link between stem cell-related transcription factor (Bmi1) and ABC transporter (ABCC5 (show ABCC5 Proteins)) but also contributes to development of potential therapeutics against breast cancer.

  9. our findings demonstrate that coexpression of Bmi1 and KRASG12D could lead to transformation of human pancreatic duct-derived cells cells in vitro

  10. In conclusion, BMI1 expression in primary tumors of stage II colon cancer patients could not predict relapse or overall survival of the patients.

Mouse (Murine) BMI1 Polycomb Ring Finger Oncogene (BMI1) interaction partners

  1. Bmi1 deletion could substitute for Gata4 (show GATA4 Proteins) during iCM reprogramming. Thus, Bmi1 acts as a critical epigenetic barrier to iCM production. Bypassing this barrier simplifies iCM generation and increases yield, potentially streamlining iCM production for therapeutic purposes.

  2. Cardiac Bmi1 progenitor cells respond to cardiac injury, contributing to the generation of de novo cardiomyocytes in the adult mouse heart.

  3. Bmi1 is a potential driver oncogene (show RAB1A Proteins) of bladder cancer, and it may become a potential treatment target for human bladder cancer.

  4. High Bmi1 expression identifies a non-cardiomyocyte resident cardiac population that contributes to the main lineages of the heart in vitro and in vivo.

  5. Here we show that inactivation of BMI1 using specific siRNA slows and decreases the levels of adipocyte differentiation , but does not abolish it.

  6. These observations suggest a dynamic and developmentally regulated model of PRC1 (show PRC1 Proteins) occupancy at constitutive heterochromatin, and where BMI1 function in somatic cells is to stabilize the repetitive genome

  7. Hypoxia models showed the mechanism by which hypoxia promoted Twist1 (show TWIST1 Proteins) and Bmi1 expression and led to vasculogenic mimicry formation.

  8. Dysregulation of the Bmi-1/p16Ink4a pathway provokes an aging-associated decline of submandibular gland function.

  9. Bmi-1 overexpression conferred extensive self-renewal capacity upon adult bone-marrow-derived self-renewing erythroblasts, which normally have limited proliferative potential.

  10. Lgr6 (show LGR6 Proteins) and Bmi1 have roles in stem cells in the acral epithelium that participate in the long-term maintenance of sweat glands, ducts, and interadnexal epidermis, while Lgr5 (show LGR5 Proteins) has a role in rapid cycling and maintance of sweat glands only

BMI1 Protein Profile

Protein Summary

Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones\; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2 (By similarity).

Alternative names and synonyms associated with BMI1

  • BMI1 polycomb ring finger oncogene (LOC100230513)
  • BMI1 polycomb ring finger oncogene (LOC100358360)
  • B lymphoma Mo-MLV insertion region 1a (bmi1a)
  • BMI1 polycomb ring finger oncogene (BMI1)
  • Bmi1 polycomb ring finger oncogene (Bmi1)
  • AW546694 protein
  • BMI-1 protein
  • bmi1 protein
  • FLVI2/BMI1 protein
  • Pcgf4 protein
  • psc1 protein
  • RNF51 protein
  • wu:fb17g03 protein
  • wu:fd18f06 protein

Protein level used designations for BMI1

BMI1 polycomb ring finger oncogene , B lymphoma Mo-MLV insertion region 1 homolog , polycomb complex protein BMI-1-A , polycomb group RING finger protein 4-A , polycomb group ring finger 4 , flvi-2/bmi-1 , murine leukemia viral (bmi-1) oncogene homolog , polycomb complex protein BMI-1 , polycomb group RING finger protein 4 , polycomb group protein Bmi1 , ring finger protein 51 , B lymphoma Mo-MLV insertion region 1 , B lymphoma Mo-MLV insertion region

GENE ID SPECIES
100230513 Taeniopygia guttata
100358360 Oryctolagus cuniculus
321505 Danio rerio
648 Homo sapiens
510666 Bos taurus
12151 Mus musculus
307151 Rattus norvegicus
487097 Canis lupus familiaris
554342 Felis catus
493647 Gallus gallus
100009347 Oryctolagus cuniculus
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