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Browse our CDCA8 Proteins (CDCA8)

Full name:
Cell Division Cycle Associated 8 Proteins (CDCA8)
On www.antibodies-online.com are 11 Cell Division Cycle Associated 8 (CDCA8) Proteins from 5 different suppliers available. Additionally we are shipping CDCA8 Antibodies (98) and CDCA8 Kits (4) and many more products for this protein. A total of 120 CDCA8 products are currently listed.
Synonyms:
4831429J16Rik, AU044747, BOR, borea, Borealin, Borr, cdca8l, CG4454, D4Ertd421e, Dasra-B, DASRAB, dBor, Dmel\\CG4454, GgDasraB, MESRGP, sb:cb373, zgc:101607
list all proteins Gene Name GeneID UniProt
CDCA8 55143 Q53HL2
CDCA8 52276 Q8BHX3
Rat CDCA8 CDCA8 500545 Q6AXW0

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CDCA8 Proteins (CDCA8) by Origin

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Top referenced CDCA8 Proteins

  1. Human CDCA8 Protein expressed in Escherichia coli (E. coli) - ABIN667908 : Chang, Chen, Wang, Chiang, Huang, Wong, Chou, Chen: Borealin/Dasra B is a cell cycle-regulated chromosomal passenger protein and its nuclear accumulation is linked to poor prognosis for human gastric cancer. in Experimental cell research 2006 (PubMed)
    Show all 2 references for ABIN667908

More Proteins for CDCA8 Interaction Partners

Fruit Fly (Drosophila melanogaster) Cell Division Cycle Associated 8 (CDCA8) interaction partners

  1. Borr interacts and colocalizes with the E (show CHMP4A Proteins)SCRT-III component Shrb in Drosophila cells.

Human Cell Division Cycle Associated 8 (CDCA8) interaction partners

  1. Borealin dimerization mediates chromosomal passenger complex checkpoint function by enhancing localization to centromeres and kinetochores.

  2. enhanced CDCA8 promoter activities by NF-Y overexpression and reduced CDCA8 transcription by NF-Y knockdown further verified that NF-Y is a positive regulator of CDCA8 transcription.

  3. In colorectal cancer patients, Borealin expression was positively correlated with age, lymph node metastasis and neoplasm staging.

  4. These findings reveal a previously unrecognized but direct link between HP1 (show DEFA1 Proteins) and CPC localization in the centromere and illustrate the critical role of borealin-HP1 (show DEFA1 Proteins) interaction in orchestrating an accurate cell division.

  5. Borealin interacts directly with the Snf7 (show CHMP4A Proteins) components of ESCRT-III in human cells.the Borealin central region encompassing residues 110-207 was both necessary & sufficient to bind to CHMP4C (show CHMP4C Proteins).

  6. MLL5 functionally interacts with Borealin, facilitates the expression of chromosomal passenger complex, and hence contributes to mitotic fidelity and genomic integrity.

  7. important role for phosphorylation of Borealin at S219 in the proper progression through mitosis

  8. Data show that INCENP (show INCENP Proteins) has an important role in stabilizing the chromosomal passenger complex, and that Borealin acts to promote binding of Survivin (show BIRC5 Proteins) to INCENP (show INCENP Proteins).

  9. Cell cycle-regulated chromosomal passenger protein (show INCENP Proteins) whose aberrant expression and nuclear accumulation are linked to poor prognosis for gastric cancer.

  10. A functional module within the chromosomal passenger complex involving the inner centromere protein INCENP (show INCENP Proteins), Survivin (show BIRC5 Proteins), and Borealin.

Mouse (Murine) Cell Division Cycle Associated 8 (CDCA8) interaction partners

  1. Borealin plays a crucial role in the early mouse embryonic development

  2. Borealin/DasraB is essential for cell proliferation during early embryonic development, and its early embryonic lethality cannot be rescued by the loss of p53 (show TP53 Proteins)

CDCA8 Protein Profile

Protein Summary

This gene encodes a component of the chromosomal passenger complex. This complex is an essential regulator of mitosis and cell division. This protein is cell-cycle regulated and is required for chromatin-induced microtubule stabilization and spindle formation. Alternate splicing results in multiple transcript variants. Pseudgenes of this gene are found on chromosomes 7, 8 and 16.

Alternative names and synonyms associated with CDCA8

  • cell division cycle associated 8 (cdca8)
  • cell division cycle associated 8 (CDCA8)
  • cell division cycle associated 8 (LOC100354320)
  • borealin-related (borr)
  • Borealin (CDCA8)
  • Borealin (borea)
  • cell division cycle associated 8 (Cdca8)
  • 4831429J16Rik protein
  • AU044747 protein
  • BOR protein
  • borea protein
  • Borealin protein
  • Borr protein
  • cdca8l protein
  • CG4454 protein
  • D4Ertd421e protein
  • Dasra-B protein
  • DASRAB protein
  • dBor protein
  • Dmel\\CG4454 protein
  • GgDasraB protein
  • MESRGP protein
  • sb:cb373 protein
  • zgc:101607 protein

Protein level used designations for CDCA8

borealin , cell division cycle-associated protein 8 , chromosomal passenger complex protein Dasra B , cell division cycle associated 8 , Borealin-related , CG4454-PA , CG4454-PB , borr-PA , borr-PB , Cell division cycle-associated protein 8 , Borealin , Dasra B , dasra-B , hDasra-B , pluripotent embryonic stem cell-related gene 3 protein , MESrg , embryonic stem cell-related , xDasraB , DrDasraB , cb373 , dasraB

GENE ID SPECIES
444885 Xenopus (Silurana) tropicalis
456762 Pan troglodytes
608164 Canis lupus familiaris
100354320 Oryctolagus cuniculus
34245 Drosophila melanogaster
777014 Gallus gallus
100195587 Salmo salar
55143 Homo sapiens
52276 Mus musculus
500545 Rattus norvegicus
425084 Gallus gallus
508022 Bos taurus
444884 Xenopus laevis
492815 Danio rerio
100174395 Pongo abelii
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