Browse our CDKN1A (CDKN1A) ELISA Kits

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Cyclin-Dependent Kinase Inhibitor 1A ELISA Kits (CDKN1A)
On www.antibodies-online.com are 10 Cyclin-Dependent Kinase Inhibitor 1A (CDKN1A) ELISA Kits from 4 different suppliers available. Additionally we are shipping CDKN1A Antibodies (4) and CDKN1A Proteins (3) and many more products for this protein. A total of 17 CDKN1A products are currently listed.
Synonyms:
CAP20, CDKI, Cdkn1, CIP1, MDA-6, mda6, P21, p21Cip1, p21WAF, SDI1, Waf1
list all ELISA KIts Gene Name GeneID UniProt
CDKN1A 1026 P38936
CDKN1A 12575 P39689
CDKN1A    

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More ELISA Kits for CDKN1A Interaction Partners

Human Cyclin-Dependent Kinase Inhibitor 1A (CDKN1A) interaction partners

  1. SUMO and p21Cip1 regulate the transit of proteins through the nucleolus; disruption of nucleolar export by DNA damage induces SUMO and p21Cip1 to act as hub proteins to form a multiprotein complex in the nucleolus.

  2. HULC activates p53 (show TP53 ELISA Kits)-p21 pathway and promotes nasopharyngeal carcinoma cell growth.

  3. We characterized the effect of the novel loci through pathway analysis and found that pathways involved are not entirely distinct as assumed so far. Further, we identified a novel association between CDKN1A and POAG. Using a zebrafish model we show that six6b (associated with POAG and optic nerve head variation) alters the expression of cdkn1a

  4. miRNAs miR (show MLXIP ELISA Kits)-106b and miR (show MLXIP ELISA Kits)-20a that target p21 were specifically downregulated in HIV-1 infected CD4 (show CD4 ELISA Kits)+ T cells.

  5. Increased nuclear localization of p21(WAF1/CIP1) in SPRY2 (show SPRY2 ELISA Kits) downregulated colon cancer cells may explain the inhibition of cell proliferation in colon cancer cells.

  6. This article discusses the controversial aspects of the two-faced involvement of p21 in cancer and speculate on how this new information may increase our understanding of its role in cancer pathogenesis. Prevailing notions indicate that p21 might also act as antiapoptotic agent, which may have relevant implications for future therapeutic strategies. [review]

  7. In this study, we found upregulation of several hemostasis-related genes, including the thrombin (show F2 ELISA Kits)-activatable receptor PAR-1 (protease-activated receptor-1 (show F2R ELISA Kits)), in Runx1 (show RUNX1 ELISA Kits)/Cbfb (show CBFB ELISA Kits)-deleted MLL (show MLL ELISA Kits)-AF9 (show MLLT3 ELISA Kits) cells. Similar to the effect of Runx1 (show RUNX1 ELISA Kits)/Cbfb (show CBFB ELISA Kits) deletion, PAR-1 (show MARK2 ELISA Kits) overexpression induced CDKN1A/p21 expression and attenuated proliferation in MLL (show MLL ELISA Kits)-AF9 (show MLLT3 ELISA Kits) cells

  8. Results provide evidence that Foxp3 (show FOXP3 ELISA Kits) is a downstream target of p53 (show TP53 ELISA Kits) and that is sufficient to induce p21 expression, ROS (show ROS1 ELISA Kits) production and p53 (show TP53 ELISA Kits)-mediated senescence.

  9. both in vitro and in vivo studies proved that CypD (show CYPD ELISA Kits) inhibitor-based treatment was able to efficiently impair this interaction, leading to a tumor formation reduction. All together, these findings indicate that the countering effect of CypD (show CYPD ELISA Kits) on the p53 (show TP53 ELISA Kits)-p21 pathway participates in oncogene (show RAB1A ELISA Kits)-dependent transformation.

  10. The deletion of CBX3 (show CBX3 ELISA Kits) directly enforces the expression of CDK6 (show CDK6 ELISA Kits) and p21.

Mouse (Murine) Cyclin-Dependent Kinase Inhibitor 1A (CDKN1A) interaction partners

  1. Data show that Emu-Myc (show MYC ELISA Kits) mice lacking both p21 and PUMA (show BBC3 ELISA Kits) developed lymphoma at a rate considerably longer latency than Emu-Myc (show MYC ELISA Kits);p53 (show TP53 ELISA Kits)(+/-)mice.

  2. Study reports that p27 (show CDKN1B ELISA Kits) normally exerts a negative feedback on p21 expression: p27 (show CDKN1B ELISA Kits) directly represses the expression of the transcription factor Pitx2 (show PITX2 ELISA Kits) which in turn maintains decreased p21 levels. Consequently, in cells lacking p27 (show CDKN1B ELISA Kits), de-repression of Pitx2 (show PITX2 ELISA Kits) causes the up-regulation of p21 showing a new mechanism by which p27 (show CDKN1B ELISA Kits) regulates cell cycle progression by transcriptionally regulating the expression of Pitx2 (show PITX2 ELISA Kits) and p21.

  3. p21-associated inhibition of early-stage malignant progression and the intense expression in papilloma outgrowths, identifies a novel, significant antagonism between p21 and ras(Ha)/ROCK2 (show ROCK2 ELISA Kits)/NF-kappaB (show NFKB1 ELISA Kits) signalling in skin carcinogenesis.these data show that ROCK2 (show ROCK2 ELISA Kits) activation induces malignancy in ras(Ha)-initiated/promoted papillomas in the context of p53 (show TP53 ELISA Kits) loss and novel NF-kappaB (show NFKB1 ELISA Kits) expression

  4. In this study, we found upregulation of several hemostasis-related genes, including the thrombin (show F2 ELISA Kits)-activatable receptor PAR-1 (protease-activated receptor-1 (show F2R ELISA Kits)), in Runx1 (show RUNX1 ELISA Kits)/Cbfb (show CBFB ELISA Kits)-deleted MLL (show MLL ELISA Kits)-AF9 (show MLLT3 ELISA Kits) cells. Similar to the effect of Runx1 (show RUNX1 ELISA Kits)/Cbfb (show CBFB ELISA Kits) deletion, PAR-1 (show MARK2 ELISA Kits) overexpression induced CDKN1A/p21 expression and attenuated proliferation in MLL (show MLL ELISA Kits)-AF9 (show MLLT3 ELISA Kits) cells

  5. both in vitro and in vivo studies proved that CypD (show CYPD ELISA Kits) inhibitor-based treatment was able to efficiently impair this interaction, leading to a tumor formation reduction. All together, these findings indicate that the countering effect of CypD (show CYPD ELISA Kits) on the p53 (show TP53 ELISA Kits)-p21 pathway participates in oncogene (show RAB1A ELISA Kits)-dependent transformation.

  6. FLT3 (show FLT3 ELISA Kits)-ITD is capable of inhibiting FLT3 (show FLT3 ELISA Kits)-ITD+ cell proliferation through the p21/Pbx1 (show PBX1 ELISA Kits) axis

  7. These data reveal a novel role for p21/waf1 in the resolution of inflammation via its ability to control neutrophil apoptosis.

  8. the silencing of Cyclin-dependent kinase 5 (show CDK5 ELISA Kits) preventing memory dysfunction

  9. Results show that p21 expression is regulated by OLA1 (show OLA1 ELISA Kits) to promote cell proliferation and organogenesis.

  10. AS160 regulates glucose-independent eukaryotic cell proliferation through p21-dependent control of the cell cycle.

CDKN1A Antigen Profile

Antigen Summary

This gene encodes a potent cyclin-dependent kinase inhibitor. The encoded protein binds to and inhibits the activity of cyclin-CDK2 or -CDK4 complexes, and thus functions as a regulator of cell cycle progression at G1. The expression of this gene is tightly controlled by the tumor suppressor protein p53, through which this protein mediates the p53-dependent cell cycle G1 phase arrest in response to a variety of stress stimuli. This protein can interact with proliferating cell nuclear antigen (PCNA), a DNA polymerase accessory factor, and plays a regulatory role in S phase DNA replication and DNA damage repair. This protein was reported to be specifically cleaved by CASP3-like caspases, which thus leads to a dramatic activation of CDK2, and may be instrumental in the execution of apoptosis following caspase activation. Multiple alternatively spliced variants have been found for this gene.

Alternative names and synonyms associated with CDKN1A

  • cyclin-dependent kinase inhibitor 1A (p21, Cip1) (CDKN1A) Elisa Kit
  • cyclin-dependent kinase inhibitor 1A (P21) (Cdkn1a) Elisa Kit
  • CAP20 Elisa Kit
  • CDKI Elisa Kit
  • Cdkn1 Elisa Kit
  • CIP1 Elisa Kit
  • MDA-6 Elisa Kit
  • mda6 Elisa Kit
  • P21 Elisa Kit
  • p21Cip1 Elisa Kit
  • p21WAF Elisa Kit
  • SDI1 Elisa Kit
  • Waf1 Elisa Kit

Protein level used designations for CDKN1A

CDK-interacting protein 1 , CDK-interaction protein 1 , DNA synthesis inhibitor , cyclin-dependent kinase inhibitor 1 , melanoma differentiation associated protein 6 , wild-type p53-activated fragment 1 , melanoma differentiation-associated protein , p21

GENE ID SPECIES
1026 Homo sapiens
12575 Mus musculus
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