Browse our CDKN1B Proteins (CDKN1B)

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Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) Proteins (CDKN1B)
On are 18 Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B) Proteins from 9 different suppliers available. Additionally we are shipping CDKN1B Antibodies (738) and CDKN1B Kits (17) and many more products for this protein. A total of 823 CDKN1B products are currently listed.
1500011J20Rik, 2610202L11Rik, AA408329, AI843786, Bridge-1, Cdki1b, cdkn1b, cdkn1bl, CDKN4, CIB, CIBP, FAM14D, ISG12, ISG12A, Kip1, MEN1B, MEN4, P27, P27KIP1, PRKDCIP, sb:cb611, SIP2-28, wu:fb63g10, wu:fb64g10, wu:fe18e03
list all proteins Gene Name GeneID UniProt
CDKN1B 10519 Q99828
CDKN1B 12576 P46414
CDKN1B 83571  

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CDKN1B Proteins (CDKN1B) by Origin

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Top referenced CDKN1B Proteins

  1. Human CDKN1B Protein expressed in Escherichia coli (E. coli) - ABIN667591 : Ishida, Kitagawa, Hatakeyama, Nakayama: Phosphorylation at serine 10, a major phosphorylation site of p27(Kip1), increases its protein stability. in The Journal of biological chemistry 2000 (PubMed)
    Show all 2 references for 667591

More Proteins for CDKN1B Interaction Partners

Human Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B) interaction partners

  1. Our study has confirmed that altered expressions of the p16 and p27 (show PAK2 Proteins) proteins might be useful biomarkers in the progression of laryngeal squamous cell carcinomas

  2. This study to analyses cytoplasmic localization of p27 (show PAK2 Proteins) in OSCC and correlates it with prognosis. Cytoplasmic localization is associated with poor prognosis in OSCC with lymph node metastasis.

  3. Data show that the resveratrol/docetaxel combination up regulated the expression of tumor supressor p53 (p53 (show TP53 Proteins)), and cell cycle inhibitors p21WAF1/CIP1 and p27KIP1.

  4. Results show that AMPKa2 regulates cellular proliferation in bladder cancer through p27 and that AMPK-mediated control of p27 is SKP2 dependent.

  5. ATM (show ATM Proteins) phosphorylates p27Kip1 on a previously uncharacterized residue (Ser (show SIGLEC1 Proteins)-140), which leads to its stabilization after induction of DNA double-strand breaks.

  6. High KIP1 expression is associated with Metastasis in Osteosarcoma.

  7. The lack of somatic CDKN1B mutations in our samples points to a rare involvement in parathyroid adenomas, despite the frequent loss of nuclear p27 (show PAK2 Proteins) expression. MEN1 (show MEN1 Proteins) biallelic inactivation seems to be directly related to down-regulation of p27 (show PAK2 Proteins) expression through the inhibition of CDKN1B gene transcription.

  8. our results provide strong evidence that CD244 (show CD244 Proteins) co-operates with c-Kit to regulate leukemogenesis through SHP-2 (show PTPN11 Proteins)/p27 (show PAK2 Proteins) signaling.

  9. The anti-proliferative effect of silibinin on LX-2 human stellate cells is via the inhibition of the expressions of various cell cycle targets including TP53 (show TP53 Proteins), p27 (show PAK2 Proteins), Akt (show AKT1 Proteins) and sirtuins.

  10. Our study was the first to screen for CDKN1B mutations, which have been shown to cause MEN4, in a Chinese population. Nevertheless, no CDKN1B mutation was detected in the present study, which supports the rarity of CDKN1B gene mutation.

Mouse (Murine) Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B) interaction partners

  1. Fbxo7 (show FBXO7 Proteins)-deficient immature thymocytes failed to undergo expansion in the thymus due to a lack of Cdk6 (show CDK6 Proteins) activity, while mature T cells showed enhanced proliferative capacity upon T-cell receptor engagement due to reduced p27 levels. These studies reveal differential cell cycle regulation by Fbxo7 (show FBXO7 Proteins) at different stages in T-cell development.

  2. systems-level control of cell cycle arrest by pRB (show PGR Proteins)-E2F (show E2F1 Proteins) and p27-CDK (show CDK4 Proteins) regulation, is reported.

  3. Results demonstrated that the addition of oncogenic mutations, such as loss of p27 or p53 (show TP53 Proteins), promotes ovarian tumor development from the benign adenomas of germ cell-deficient (show FANCL Proteins) ovaries.

  4. p27 inactivation promotes injury islet graft loss via the elevation of proliferation and inflammatory cytokines secretion in infiltrating macrophages which induced nonspecific inflammation independent of TNF-alpha (show TNF Proteins)/nuclear factor-kappa b pathway. T

  5. Knockout of p27 enhances arterial collateralization in response to hindlimb ischemia through enlargement of a new collateral pathway.

  6. These data illuminate a genetic pathway that initiates auditory HC regeneration and suggest p27(Kip1), GATA3 (show GATA3 Proteins), and POU4F3 (show POU4F3 Proteins) as additional therapeutic targets for ATOH1 (show ATOH1 Proteins)-mediated auditory hair cells regeneration.

  7. Cdkn1b exert its effects via the inhibition of proliferation and is mediated by miR (show MLXIP Proteins)-24 and targeted by the transcription factors FOXO4 (show FOXO4 Proteins) and AP4 (show REPIN1 Proteins) in the peroxidasin (Pxdn (show PXDN Proteins)) mutation-induced eye disorders, such as glaucoma.

  8. These results suggest that fad24 (show NOC3L Proteins) may have an important role in the S phase re-entry of quiescent C2C12 cells through the regulation of p27(Kip1) at the protein level

  9. The down-regulation of p27 and the activation of mTOR (show FRAP1 Proteins) pathway may be involved in miR (show MLXIP Proteins)-222-induced heart failure and autophagy inhibition.

  10. Used LDLr (show LDLR Proteins) knockout mice to identify the effects of Kiom-18 as a preliminary result in an atherosclerosis animal model; the level of p27(kip1) expression was upregulated in the presence of the Kiom-18 extract.

Pig (Porcine) Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B) interaction partners

  1. FoxO1a (show FOXO1 Proteins) can regulate p27kip nuclear localization

  2. the activation of Rac1 due to the cell-cell contact plays a critical role in the transcriptional up-regulation of p27Kip1 in vascular endothelial cells.

Cow (Bovine) Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B) interaction partners

  1. p27Kip1 inhibition has an effect on proliferation of bovine corneal endothelial cells by RNA interferenc

Zebrafish Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B) interaction partners

CDKN1B Protein Profile

Protein Summary

Important regulator of cell cycle progression. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1- CDK4 complex activation. Acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry (By similarity).

Alternative names and synonyms associated with CDKN1B

  • cyclin-dependent kinase inhibitor 1B (p27, Kip1) (CDKN1B)
  • calcium and integrin binding 1 (calmyrin) (CIB1)
  • cyclin kinase inhibitor p30 Kip1 (LOC100689401)
  • cyclin-dependent kinase inhibitor 1B (Cdkn1b)
  • cyclin-dependent kinase inhibitor 1B (p27, Kip1) (Cdkn1b)
  • cyclin-dependent kinase inhibitor 1Ba (cdkn1ba)
  • cyclin-dependent kinase inhibitor 1Bb (cdkn1bb)
  • interferon, alpha-inducible protein 27 (IFI27)
  • proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 (Psmd9)
  • 1500011J20Rik protein
  • 2610202L11Rik protein
  • AA408329 protein
  • AI843786 protein
  • Bridge-1 protein
  • Cdki1b protein
  • cdkn1b protein
  • cdkn1bl protein
  • CDKN4 protein
  • CIB protein
  • CIBP protein
  • FAM14D protein
  • ISG12 protein
  • ISG12A protein
  • Kip1 protein
  • MEN1B protein
  • MEN4 protein
  • P27 protein
  • P27KIP1 protein
  • PRKDCIP protein
  • sb:cb611 protein
  • SIP2-28 protein
  • wu:fb63g10 protein
  • wu:fb64g10 protein
  • wu:fe18e03 protein

Protein level used designations for CDKN1B

cyclin-dependent kinase inhibitor 1B (p27, Kip1) , cyclin-dependent kinase inhibitor 1B , DNA-PK interaction protein , DNA-PKcs-interacting protein , DNA-dependent protein kinase interacting protein , SNK-interacting protein 2-28 , calcium and integrin-binding protein 1 , Cyclin-dependent kinase inhibitor p27 , cyclin-dependent kinase inhibitor p27 , Cyclin-dependent kinase inhibitor 1B (p27 Kip1) , Cyclin-dependent kinase inhibitor 1B (p27, Kip1) , cyclin-dependent kinase inhibitor p27/Kip1 , p27Kip1 , cyclin-dependent kinase inhibitor 1b, like , kip1 , p27 , cyclin-dependent kinase inhibitor 1b (p27, kip1) , fb64g10 , 2310061N23Rik , ISG12(a) , interferon alpha-induced 11.5 kDa protein , interferon alpha-inducible protein 27, mitochondrial , interferon-stimulated gene 12a protein , 26S proteasome non-ATPase regulatory subunit 9 , 26S proteasome regulatory subunit p27

466947 Pan troglodytes
697188 Macaca mulatta
769872 Gallus gallus
100127219 Ovis aries
10519 Homo sapiens
100689401 Cricetulus griseus
12576 Mus musculus
83571 Rattus norvegicus
1027 Homo sapiens
403429 Canis lupus familiaris
374106 Gallus gallus
397584 Sus scrofa
512613 Bos taurus
100729359 Cavia porcellus
493958 Felis catus
402862 Danio rerio
368329 Danio rerio
3429 Homo sapiens
67151 Mus musculus
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