Browse our Cyclin E1 Proteins (CCNE1)

Full name:
Cyclin E1 Proteins (CCNE1)
On are 14 Cyclin E1 (CCNE1) Proteins from 5 different suppliers available. Additionally we are shipping Cyclin E1 Antibodies (281) and Cyclin E1 Kits (17) and many more products for this protein. A total of 339 Cyclin E1 products are currently listed.
AW538188, Ccne, CCNE1, cyce, CycE1, cyce2, cycE3, CYCLE, cyclinE, fa18e07, wu:fa18e07
list all proteins Gene Name GeneID UniProt
CCNE1 898 P24864
CCNE1 12447 Q61457
CCNE1 25729  

Show all synonyms

Cyclin E1 Proteins (CCNE1) by Origin

Select your origin of interest

More Proteins for Cyclin E1 Interaction Partners

Human Cyclin E1 (CCNE1) interaction partners

  1. Inhibition of cell division cycle associated 2 (CDCA2) suppressed the proliferation of lung adenocarcinoma (LAC (show LCT Proteins)) cells via G1 phase arrest by downregulating cyclin E1(CCNE1), while overexpression of CDCA2 promoted LAC (show LCT Proteins) cells proliferation by upregulating CCNE1.

  2. a PI3K (show PIK3CA Proteins)/PKCiota/cyclin E signaling pathway as a therapeutic target during ovarian tumorigenesis

  3. Amplification of the G1-S regulatory genes, CCNE1, CCND1 and CdK6, represent an early event, which precedes ERBB2, EGFR, or KRAS amplification in gastric adenocarcinoma.

  4. Amplification of 19q12 CCNE1/URI was found in 10.4% (28/270) and was significantly associated with type II endometrial cancer (EC) high grade, advanced FIGO stage, and aberrant tumor supressor p53 (show TP53 Proteins) expression.

  5. Data reveal that the presence of rs200996365, a SNP in high-linkage disequilibrium with rs8102137 residing in the center of a KLF5 (show KLF5 Proteins) motif, alters KLF5 (show KLF5 Proteins) binding to this genomic region and provide evidence that KLF5 (show KLF5 Proteins) binds CCNE1 polymorphic intronic enhancer to confer increased bladder cancer risk.

  6. Noxin facilitated the expression of Cyclin D1 (show CCND1 Proteins) and Cyclin E1 through activating P38 (show CRK Proteins)-activating transcription factor 2 (show ATF2 Proteins) signaling pathway, thus enhanced cell growth of breast cancer

  7. Results show that cyclin E1 and CDK2 (show CDK2 Proteins) participate in STC1 (show STC1 Proteins) promoting cell proliferation of prostate neoplasm cells.

  8. cyclin E is specifically dephosphorylated at S384 by the PP2A (show PPP2R4 Proteins)-B56 phosphatase, thereby uncoupling cyclin E degradation from cyclin E-CDK2 (show CDK2 Proteins) activity

  9. These results provide evidence that ARTD1 (show PARP1 Proteins) regulates cell cycle re-entry and G1/S progression via cyclin E expression and p27 (show PAK2 Proteins)(Kip 1 (show CDKN1B Proteins)) stability independently of its enzymatic activity, uncovering a novel cell cycle regulatory mechanism.

  10. These results demonstrate a repressor role for NFAT1 (show NFAT1 Proteins) in cell cycle progression and Cyclin E expression in B lymphocytes, and suggest a potential function for NFAT1 (show NFAT1 Proteins) protein in B cell malignancies.

Mouse (Murine) Cyclin E1 (CCNE1) interaction partners

  1. These results demonstrate a repressor role for NFAT1 (show NFAT1 Proteins) in cell cycle progression and Cyclin E expression in B lymphocytes, and suggest a potential function for NFAT1 (show NFAT1 Proteins) protein in B cell malignancies.

  2. This approach allowed us to determine the identity of cyclin E protein partners, as well as phosphorylation substrates of cyclins E (cyclin (show PCNA Proteins) E1and cyclin E2 (show CCNE2 Proteins))and its associated kinase, Cdk2 (show CDK2 Proteins), in different mouse organs.

  3. inhibition of PDK4 (show PDK4 Proteins) activity in Hepatocellular carcinoma cells increased cyclin E1, cyclin A2 (show CCNA2 Proteins), and E2F1 (show E2F1 Proteins) proteins.

  4. Spermatocytes lacking cyclin E2 (show CCNE2 Proteins) and one E1 allele (E1+/-E2-/-) displayed a high rate of telomere abnormalities but can progress to pachytene and diplotene stages.

  5. NF-kappaB (show NFKB1 Proteins)-miR (show MLXIP Proteins)-195/497-Igf1r (show IGF1R Proteins)/Insr (show INSR Proteins)-Ccnd2 (show CCND2 Proteins)/Ccne1 plays important roles in myogenesis.

  6. Myb (show MYB Proteins) regulates Cyclin E1 expression in normal gastrointestinal tract epithelial cells and is required during intestinal tumorigenesis

  7. These results highlight a new role for E-type cyclins (Ccne1 and Ccne2 (show CCNE2 Proteins)) as important regulators of male meiosis.

  8. Concurrent deletion of cyclin E1 and cyclin-dependent kinase 2 (show CDK2 Proteins) in hepatocytes inhibits DNA replication and liver regeneration in mice.

  9. Superoxide dismutase (show SOD1 Proteins) induces G1-phase cell cycle arrest by down-regulated expression of Cdk-2 (show CDK2 Proteins) and cyclin-E in sarcoma tumor cells.

  10. Ablation of cyclin E led to a decreased number of synapses, reduced number and volume of dendritic spines, and resulted in impaired synaptic plasticity and memory formation.

Xenopus laevis Cyclin E1 (CCNE1) interaction partners

  1. miR (show MYLIP Proteins)-15/16 and CPEB co-regulate cyclin E1 mRNA.

  2. cyclin E is dynamically and highly conjugated to SUMO2 (show SUMO2 Proteins)/3 on chromatin, independently of Cdk2 (show CDK2 Proteins) activity and origin activation.

  3. These results show that cyclin E destruction at the midblastula transition requires both phosphorylation and nuclear import, as well as proteasomal activity.

Zebrafish Cyclin E1 (CCNE1) interaction partners

  1. intestinal clock controls the expression of key cell cycle regulators, such as cdc2 (show CDK1 Proteins), wee1 (show WEE1 Proteins), p21 (show CDKN1A Proteins), PCNA (show PCNA Proteins) and cdk2 (show CDK2 Proteins), but only weakly influences cyclin B1 (show CCNB1 Proteins), cyclin B2 (show CCNB2 Proteins) and cyclin E1 expression.

Cyclin E1 (CCNE1) Protein Profile

Protein Summary

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2, whose activity is required for cell cycle G1/S transition. This protein accumulates at the G1-S phase boundary and is degraded as cells progress through S phase. Overexpression of this gene has been observed in many tumors, which results in chromosome instability, and thus may contribute to tumorigenesis. This protein was found to associate with, and be involved in, the phosphorylation of NPAT protein (nuclear protein mapped to the ATM locus), which participates in cell-cycle regulated histone gene expression and plays a critical role in promoting cell-cycle progression in the absence of pRB. Two alternatively spliced transcript variants of this gene, which encode distinct isoforms, have been described. Two additional splice variants were reported but detailed nucleotide sequence information is not yet available.

Alternative names and synonyms associated with Cyclin E1 (CCNE1)

  • cyclin E1 (CCNE1)
  • cyclin E1 (ccne1)
  • cyclin E1 (Ccne1)
  • cyclin E1 (cycE1)
  • AW538188 protein
  • Ccne protein
  • CCNE1 protein
  • cyce protein
  • CycE1 protein
  • cyce2 protein
  • cycE3 protein
  • CYCLE protein
  • cyclinE protein
  • fa18e07 protein
  • wu:fa18e07 protein

Protein level used designations for Cyclin E1 Proteins (CCNE1)

cyclin E1 , G1/S-specific cyclin-E1 , G1/S-specific cyclin-E1-like , g1/S-specific cyclin-E1-like , cyclin Es , cyclin Et , cyclin E , G1/S-specific cyclin-E2 , cyclin-E-1 , G1/S-specific cyclin-E3 , cyclin E3

455914 Pan troglodytes
484610 Canis lupus familiaris
533526 Bos taurus
549082 Xenopus (Silurana) tropicalis
700589 Macaca mulatta
100053882 Equus caballus
100396520 Callithrix jacchus
100461587 Pongo abelii
100471009 Ailuropoda melanoleuca
100523248 Sus scrofa
100607751 Nomascus leucogenys
898 Homo sapiens
12447 Mus musculus
25729 Rattus norvegicus
426117 Gallus gallus
397840 Xenopus laevis
397841 Xenopus laevis
30188 Danio rerio
Selected quality suppliers for Cyclin E1 Proteins (CCNE1)
Did you look for something else?