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Browse our Retinoblastoma 1 (RB1) ELISA Kits

Full name:
Retinoblastoma 1 ELISA Kits (RB1)
On www.antibodies-online.com are 19 Retinoblastoma 1 (RB1) ELISA Kits from 3 different suppliers available. Additionally we are shipping Retinoblastoma 1 Antibodies (594) and Retinoblastoma 1 Proteins (13) and many more products for this protein. A total of 696 Retinoblastoma 1 products are currently listed.
Synonyms:
OSRC, P105-RB, PP110, pRb, Rb, Rb-1, RB1, RB11, zgc:154147

More ELISA Kits for Retinoblastoma 1 Interaction Partners

Human Retinoblastoma 1 (RB1) interaction partners

  1. Data suggest that gamma-tocotrienol delays cellular senescence of cultured diploid fibroblasts by regulating the cell cycle through down-regulation of expression of p16-INK4a (CDKN2A/cyclin dependent kinase inhibitor 2A) mRNA, of expression/phosphorylation of retinoblastoma protein (RB1), and of expression of cyclin D1 (CCND1 (show CCND1 ELISA Kits)).

  2. TP53 (show TP53 ELISA Kits) and RB1 mutations seem to be restricted to high-risk/malignant gastrointestinal stromal tumors and occur at an equal although relatively low frequency.

  3. Increased the expression of tumor suppressor genes such as Cdkn2A, Rb1 and p53 (show TP53 ELISA Kits).

  4. By targeting genes involved in controlling pRb/E2F1 (show E2F1 ELISA Kits) activity, miR (show MLXIP ELISA Kits)-449a regulates cell cycle progression and apoptosis and consequently enhances the radiosensitivity of PC-3 (show PCSK1 ELISA Kits) cells. Thus, miR (show MLXIP ELISA Kits)-449a, as a miRNA component of the Rb pathway, promotes the radiosensitivity of PC-3 (show PCSK1 ELISA Kits) cells through regulating pRb/E2F1 (show E2F1 ELISA Kits).

  5. Data indicate that single nucleotide polymorphisms (SNPs) in cyclin D1 (show CCND1 ELISA Kits):rs9344 and retinoblastoma:rs427686 genes showed a strong correlation with disease-free survival.

  6. AR mutations and/or copy number alterations were robustly detected in 48% (31 of 65) and 60% (18 of 30) of baseline and progression samples, respectively. Detection of AR amplification, heavily mutated AR (>/=2 mutations), and RB1 loss were associated with worse progression-free survival, with hazard ratios of 2.92

  7. Identify Dyrk1a (show DYRK1A ELISA Kits) as a novel negative regulator of D-cyclin (show PCNA ELISA Kits)-mediated Rb1/E2f (show E2F1 ELISA Kits)-signalling. As dysregulation of this pathway with impaired cardiomyocyte proliferation leads to cardiomyopathy

  8. Data show that alpha-linolenic acid (ALA) decreased the expression of VEGF (show VEGFA ELISA Kits) and COX2 (show COX2 ELISA Kits) proteins, and reduced the expression of Human papillomavirus type 16/18 onco-proteins E6 and E7, resulting into restoration of expression of tumor suppressor proteins, p53 (show TP53 ELISA Kits) and Rb in cervical cancer cell lines.

  9. This review focuses on the ability of pRB to control nucleosome/chromatin structures via physical interactions with histone modifiers and chromatin factors and describes cancer therapies based on targeting these protein factors.

  10. CTDSPL (show CTDSPL ELISA Kits) and Rb directly interact and can be involved in the common mechanism of cell cycle regulation.

Mouse (Murine) Retinoblastoma 1 (RB1) interaction partners

  1. Identify Dyrk1a (show DYRK1A ELISA Kits) as a novel negative regulator of D-cyclin (show PCNA ELISA Kits)-mediated Rb1/E2f (show E2F1 ELISA Kits)-signalling. As dysregulation of this pathway with impaired cardiomyocyte proliferation leads to cardiomyopathy.

  2. Expression of Kv10.1 (show KCNG3 ELISA Kits) driven by phosphorylated Rb/E2F1 (show E2F1 ELISA Kits) contributes to G2/M progression of cancer and non-transformed cells.

  3. These findings establish that Rb1 and Skp2 deletions are synthetic lethal and suggest how this lethal relationship might be circumvented, which could help design better therapies for pRb (show PGR ELISA Kits)-deficient cancer.

  4. Results indicate that Rb and p53 (show TP53 ELISA Kits) not only function as tumor suppressors in response to carcinogenic injury, but also in response to non-carcinogenic injury.

  5. Suggest that a principal role for RB1 in development is coordinating the events required for terminal differentiation of erythroid cells.

  6. data also suggest that Rb1 loss is not sufficient to transform post-germinal center B cells and that additional, specific mutations are likely required to cooperate with Rb1 loss to induce malignant transformation.

  7. propose that by repressing Pak1 expression, Rb prevents Rac1 hyperactivity usually associated with cancer and related to cytoskeletal derangements that disrupt cell adhesion, consequently enhancing cancer cell migratory capacity

  8. Data (including data from studies in knockout/transgenic mice) suggest CDKN1B (show CDKN1B ELISA Kits)-RB1-E2F1 (show E2F1 ELISA Kits) (cyclin-dependent kinase inhibitor 1B (show CDKN1B ELISA Kits)-RB1-E2F (show E2F1 ELISA Kits) transcription 1) pathway is essential for SSC (show CYP11A1 ELISA Kits) (spermatogonial stem cell) self-renewal/protection against DNA damage.

  9. A model suited to determine the cellular function of the alternative Rb1 transcript.

  10. data indicate that Pten deletion in osteoblast precursors is sufficient to promote frequent adipogenic, but only rare osteogenic tumors. Rb1 hetero- or homo-zygous co-deletion greatly increases the incidence and the rapidity of onset of adipogenic tumors.

Zebrafish Retinoblastoma 1 (RB1) interaction partners

  1. Our results indicate that Rb-Raf-1 (show RAF1 ELISA Kits) interaction plays an important role in spontaneous hair cell regeneration in zebrafish

  2. our analysis of zebrafish rb1 mutants reveals a previously unknown yet critical role for rb1 during retinotectal tract development and visual function.

  3. Zebrafish usp39 (show USP37 ELISA Kits) regulates embryonic pituitary homeostasis by targeting rb1 and e2f4 (show E2F4 ELISA Kits) expression, respectively, contributing to increased adenohypophyseal sensitivity to these altered cell cycle regulators

Retinoblastoma 1 (RB1) Antigen Profile

Antigen Summary

The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

Alternative names and synonyms associated with Retinoblastoma 1 (RB1)

  • retinoblastoma 1 (including osteosarcoma) (RB1) Elisa Kit
  • retinoblastoma 1 (RB1) Elisa Kit
  • Retinoblastoma-associated protein (rb) Elisa Kit
  • retinoblastoma 1 (Rb1) Elisa Kit
  • retinoblastoma 1 (rb1) Elisa Kit
  • OSRC Elisa Kit
  • P105-RB Elisa Kit
  • PP110 Elisa Kit
  • pRb Elisa Kit
  • Rb Elisa Kit
  • Rb-1 Elisa Kit
  • RB1 Elisa Kit
  • RB11 Elisa Kit
  • zgc:154147 Elisa Kit

Protein level used designations for Retinoblastoma 1 (RB1) ELISA Kits

retinoblastoma 1 (including osteosarcoma) , retinoblastoma protein 1 , retinoblastoma-associated protein , Retinoblastoma-associated protein , retinoblastoma 1 , retinoblastoma-associated protein-like , retinoblastoma suspectibility protein , pp105 , retinoblastoma protein , Retinoblastoma 1 (including osteosarcoma) , pRb , rb , p104 , spc , retinoblastoma, susceptibility

GENE ID SPECIES
449604 Pan troglodytes
452715 Pan troglodytes
704871 Macaca mulatta
100217687 Taeniopygia guttata
100380330 Salmo salar
100397928 Callithrix jacchus
5925 Homo sapiens
19645 Mus musculus
476915 Canis lupus familiaris
100057080 Equus caballus
24708 Rattus norvegicus
386582 Gallus gallus
777733 Danio rerio
534712 Bos taurus
100716297 Cavia porcellus
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