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SMAD2 Proteins

(SMAD, Mothers Against DPP Homolog 2 (SMAD2))
The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signal of the transforming growth factor (TGF)-beta, and thus regulates multiple cellular processes, such as cell proliferation, apoptosis, and differentiation. This protein is recruited to the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation (SARA) protein. In response to TGF-beta signal, this protein is phosphorylated by the TGF-beta receptors. The phosphorylation induces the dissociation of this protein with SARA and the association with the family member SMAD4. The association with SMAD4 is important for the translocation of this protein into the nucleus, where it binds to target promoters and forms a transcription repressor complex with other cofactors. This protein can also be phosphorylated by activin type 1 receptor kinase, and mediates the signal from the activin. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2012].
SMAD2 Protein (AA 181-280) (GST tag) SMAD2 Protein (AA 181-280) (GST tag) SMAD2 Protein (AA 181-280) (GST tag) (ABIN1320595)

SMAD2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA

SMAD2 Protein (AA 2-467) (His tag) SMAD2 Protein (AA 2-467) (His tag) SMAD2 Protein (AA 2-467) (His tag) (ABIN7125122)

SMAD2 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA

SMAD2 Protein (AA 1-467) (His tag) SMAD2 Protein (AA 1-467) (His tag) SMAD2 Protein (AA 1-467) (His tag) (ABIN5570545)

SMAD2 Origin: Human Host: Escherichia coli (E. coli) Recombinant SDS

SMAD2 Proteins by Grade

Find SMAD2 Proteins with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

SMAD2 Proteins by Origin

Find SMAD2 Proteins for a variety of species such as anti-Human SMAD2, anti-Mouse SMAD2, anti-Cow SMAD2. The species listed below are among those available. Click on a link to go to the corresponding products.

SMAD2 Proteins by Source

Here you will find SMAD2 Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

SMAD2 Proteins by Protein Type

Here you can find SMAD2 Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

SMAD2 Proteins by Application

Find SMAD2 Proteins validated for a specific application such as ELISA, WB, SDS, AbP. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular SMAD2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1320595
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7125122
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN5570545
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Baculovirus infected Insect Cells
Validations
  • (1)
Cat. No. ABIN7320169
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3095492
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3135556
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
  • (1)
Cat. No. ABIN2732219
Quantity 20 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7318785
Quantity 50 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7395908
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7401368
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN1047400
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2732220
Quantity 20 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN6700544
Quantity 50 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN6307034
Quantity 1 mg
Datasheet Datasheet
Reactivity Cow
Source Yeast
Validations
Cat. No. ABIN1620647
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our SMAD2 Proteins

Atanelishvili, Shirai, Akter, Buckner, Noguchi, Silver, Bogatkevich: "M10, a caspase cleavage product of the hepatocyte growth factor receptor, interacts with Smad2 and demonstrates antifibrotic properties in vitro and in vivo." in: Translational research : the journal of laboratory and clinical medicine, Vol. 170, pp. 99-111, (2016) (PubMed).

Aliases for SMAD2 Proteins

SMAD family member 2 (SMAD2) Proteins
SMAD family member 2-Z (SMAD2Z) Proteins
SMAD family member 2 (smad2) Proteins
SMAD family member 2 S homeolog (smad2.S) Proteins
SMAD family member 2 (Smad2) Proteins
7120426M23Rik Proteins
fj43c06 Proteins
hMAD-2 Proteins
hmad-2 Proteins
hSMAD2 Proteins
hsmad2 Proteins
JV18 Proteins
jv18 Proteins
JV18-1 Proteins
jv18-1 Proteins
MADH2 Proteins
madh2 Proteins
Madh2 Proteins
MAD homolog 2 Proteins
MADR2 Proteins
madr2 Proteins
Madr2 Proteins
mMad2 Proteins
Mothers against DPP homolog 2 Proteins
smad-2 Proteins
Smad-2 Proteins
SMAD 2 Proteins
Smad2 Proteins
wu:fj43c06 Proteins
Xmad2 Proteins
XSmad2 Proteins
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