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Browse our SMAD3 (SMAD3) ELISA Kits

Full name:
SMAD, Mothers Against DPP Homolog 3 ELISA Kits (SMAD3)
On www.antibodies-online.com are 46 SMAD, Mothers Against DPP Homolog 3 (SMAD3) ELISA Kits from 12 different suppliers available. Additionally we are shipping SMAD3 Antibodies (466) and SMAD3 Proteins (25) and many more products for this protein. A total of 580 SMAD3 products are currently listed.
Synonyms:
AU022421, HSPC193, HsT17436, JV15-2, LDS1C, LDS3, mad3, Madh3, madh3-A, madh3a, Smad 3, smad3, wu:fa99e03, XenMLP, Xmad3, XSmad3
list all ELISA KIts Gene Name GeneID UniProt
SMAD3 4088 P84022
SMAD3 17127 Q8BUN5
SMAD3 25631 P84025

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More ELISA Kits for SMAD3 Interaction Partners

Zebrafish SMAD, Mothers Against DPP Homolog 3 (SMAD3) interaction partners

  1. Smad3 is mainly active in post-mitotic, non-proliferating cells with a role in TGF-beta (show TGFB1 ELISA Kits) control of zebrafish spinal cord development

  2. Nodal signaling and mesendoderm induction depend on Smad2 (show SMAD2 ELISA Kits)/3 and suggest that transforming growth factor-beta signals other than Nodal also contribute to Smad2 (show SMAD2 ELISA Kits)/3 signaling and embryonic patterning.

  3. although the role of Smad (show SMAD1 ELISA Kits) proteins in mediating Nodal signaling is well-documented, the functional characterization of Ttrap (show TDP2 ELISA Kits) provides insight into a novel Smad (show SMAD1 ELISA Kits) partner that plays an essential role in the fine-tuning of this signal transduction cascade

  4. Smad2 (show SMAD2 ELISA Kits)/3 activities play important roles not only in mesendodermal development but also in neural development during early vertebrate embryogenesis

Rabbit SMAD, Mothers Against DPP Homolog 3 (SMAD3) interaction partners

  1. study suggested that TGF-beta1/Smad3/smad7 is a major pathway which plays an important role in the regulation of the IUA and specific inhibitor of Smad3 (SIS3) may provide a new therapeutic strategy for IUA.

Human SMAD, Mothers Against DPP Homolog 3 (SMAD3) interaction partners

  1. SMAD3 mutations reported in patients with syndromic Aortic Aneurisms and dissections with early-onset osteoarthritis.

  2. The results also revealed the existence of crosstalk between miR (show MLXIP ELISA Kits)-29b and TGF-beta1 (show TGFB1 ELISA Kits)/Smad3 during LX-2 activation, suggesting a feedback loop between miR (show MLXIP ELISA Kits)-29b and TGF-beta1 (show TGFB1 ELISA Kits)/Smad3 signalling that promotes liver fibrosis.

  3. Smad2 (show SMAD2 ELISA Kits) and Smad3 possess differential sensitivities in relaying TGFbeta (show TGFB1 ELISA Kits) signaling and have distinct roles in regulating early developmental events.

  4. Likely pathogenic variants included a TGFB2 (show TGFB2 ELISA Kits) variant in one patient and a SMAD3 variant in another. These variants have been reported previously in individuals with similar phenotypes. Variants of uncertain significance of particular interest included novel variants in MYLK (show MYLK ELISA Kits) and MFAP5 (show MFAP5 ELISA Kits), which were identified in a third patient

  5. The more significant compound effects of two-locus models, combining single nucleotide polymorphisms (SNPs) in ADAM17 (show ADAM17 ELISA Kits) and other TGF-beta (show TGFB1 ELISA Kits) signaling pathway genes including TGFB2 (show TGFB2 ELISA Kits) and SMAD3, on KD phenotypes relative to single SNPs suggest that ADAM17 (show ADAM17 ELISA Kits) is also involved in secondary CAL (show FBLIM1 ELISA Kits) formation and confers the risk of KD/CALs (show CA8 ELISA Kits) via the TGF-beta (show TGFB1 ELISA Kits)/SMAD3 signaling pathway.

  6. Exogenous expression of miR (show MLXIP ELISA Kits)-142-5p inhibitor resulted in a significant reduction of viral titer indicating proviral role of miR (show MLXIP ELISA Kits)-142-5p. Functional studies of hsa (show CD24 ELISA Kits)-miR (show MLXIP ELISA Kits)-142-5p identified its role in transforming growth factor beta (TGFbeta (show TGFB1 ELISA Kits)) signalling as TGFbeta (show TGFB1 ELISA Kits) receptor 2 and SMAD3 were degraded during both hsa (show CD24 ELISA Kits)-miR (show MLXIP ELISA Kits)-142-5p overexpression and rotavirus infection.

  7. These findings pinpoint that TGF-beta (show TGFB1 ELISA Kits) represses miR (show MLXIP ELISA Kits)-30d through a Smad2 (show SMAD2 ELISA Kits)/3-HDAC3 (show HDAC3 ELISA Kits)-NCoR (show NCOR1 ELISA Kits) repression complex and provide novel insights into a potential target for the treatment of podocyte injury-associated glomerulopathies.

  8. study suggested that TGF-beta1/Smad3/smad7 is a major pathway which plays an important role in the regulation of the IUA and specific inhibitor of Smad3 (SIS3) may provide a new therapeutic strategy for IUA.

  9. these data demonstrate that the SMI drives ES cells to skeletal muscle via concerted activation of the Wnt (show WNT2 ELISA Kits) pathway, and inhibition of Smad2 (show SMAD2 ELISA Kits)/3 signaling and Shh (show SHH ELISA Kits) pathways.

  10. Our study demonstrates that SMAD3 is significantly overexpressed in osteoarthritis. This overexpression cannot be explained by DNA methylation (show HELLS ELISA Kits) in the promoter region.

Xenopus laevis SMAD, Mothers Against DPP Homolog 3 (SMAD3) interaction partners

  1. E2a (show TCF3 ELISA Kits) is necessary to drive transcription of Smad2 (show SMAD2 ELISA Kits)/3 target genes, including critical regulators of dorsal cell fate and morphogenesis

Pig (Porcine) SMAD, Mothers Against DPP Homolog 3 (SMAD3) interaction partners

  1. Smad3 regulate the activity and stability of myocardin (show MYOCD ELISA Kits)-related transcription factor during epithelial-myofibroblast transition

  2. SP1 (show SP1 ELISA Kits) and SMAD3 are required for high glucose-induced p21(WAF1 (show CDKN1A ELISA Kits)) gene transcription in LLC-PK1 (show PKLR ELISA Kits) cells.

Mouse (Murine) SMAD, Mothers Against DPP Homolog 3 (SMAD3) interaction partners

  1. Activation of CB2 (show CNR2 ELISA Kits) ameliorates myocardial fibrosis via Nrf2 (show NFE2L2 ELISA Kits)-mediated inhibition of TGF-beta1 (show TGFB1 ELISA Kits)/Smad3 pathway in mice with myocardial infarction.

  2. This study found evidence of increased leukocyte phosphorylated-Smad2 (show SMAD2 ELISA Kits)/3 staining in both single leukocytes and platelet-leukocyte aggregates in mice that developed aortic valve stenosis, suggesting the presence of increased circulating active TGF-beta1 (show TGFB1 ELISA Kits).

  3. The findings indicate that active Yap1 (show YAP1 ELISA Kits) promotes the self-renewal of breast Tumor initiating cells by inhibiting Smad3 signaling.

  4. Data show that muscle-specific (show EIF3K ELISA Kits) Smad (show SMAD1 ELISA Kits) proteins Smad2 (show SMAD2 ELISA Kits)/3-deficient mice exhibited significant resistance to denervation-induced muscle atrophy.

  5. Arsenite disrupts zinc-dependent TGFbeta2-SMAD2 (show SMAD2 ELISA Kits)/3 activity during murine cardiac progenitor cell differentiation.

  6. This study showed that Smad3 deficiency inhibits LTP (show SCP2 ELISA Kits) induction by enhancing phasic and tonic GABAA (show GABRg1 ELISA Kits) receptor-mediated neurotransmission.

  7. Suggest that hyperoxia-increased high-tidal-volume ventilation-induced acute lung injury partially depends on the Src (show SRC ELISA Kits) and Smad3 pathways.

  8. Smad3 is a key transcriptional factor of TGF-beta (show TGFB1 ELISA Kits) signaling that differentially regulates T cell immune responses in a mouse model of cardiac allograft rejection

  9. Smad2 (show SMAD2 ELISA Kits) and Smad3 oppositely modify STAT3 (show STAT3 ELISA Kits)-induced transcription of IL-17A (show IL17A ELISA Kits) and retinoic acid receptor (show RARA ELISA Kits)-related orphan nuclear receptor (show NR1D1 ELISA Kits), RORgammat encoded by Rorc (show RORC ELISA Kits), by acting as a co-activator and co-repressor of STAT3 (show STAT3 ELISA Kits), respectively.

  10. Smad3 deficiency leads to mandibular condyle degradation via the sphingosine 1-phosphate (S1P (show S1PR1 ELISA Kits))/S1P3 (show S1PR3 ELISA Kits) signaling axis

Cow (Bovine) SMAD, Mothers Against DPP Homolog 3 (SMAD3) interaction partners

  1. the present work provides evidence supporting a functional role of SMAD2 (show SMAD2 ELISA Kits)/3 in bovine early embryogenesis

  2. Mechanical compression not only with physiological but also with excessive stress can activate Smad2 (show SMAD2 ELISA Kits)/3P signaling, which is known to be protective for articular cartilage and to block chondrocyte terminal differentiation.

  3. a detailed computational model for TGF-beta (show TGFB1 ELISA Kits) signalling that incorporates elements of previous models together with crosstalking between Smad1 (show SMAD1 ELISA Kits)/5/8 and Smad2 (show SMAD2 ELISA Kits)/3 channels through a negative feedback loop dependent on Smad7 (show SMAD7 ELISA Kits).

SMAD3 Antigen Profile

Antigen Summary

The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis.

Alternative names and synonyms associated with SMAD3

  • SMAD family member 3 (SMAD3) Elisa Kit
  • MAD homolog 3a (Drosophila) (smad3a) Elisa Kit
  • mothers against decapentaplegic homolog 3 (LOC100346303) Elisa Kit
  • SMAD family member 3 (smad3) Elisa Kit
  • SMAD family member 3 (Smad3) Elisa Kit
  • AU022421 Elisa Kit
  • HSPC193 Elisa Kit
  • HsT17436 Elisa Kit
  • JV15-2 Elisa Kit
  • LDS1C Elisa Kit
  • LDS3 Elisa Kit
  • mad3 Elisa Kit
  • Madh3 Elisa Kit
  • madh3-A Elisa Kit
  • madh3a Elisa Kit
  • Smad 3 Elisa Kit
  • smad3 Elisa Kit
  • wu:fa99e03 Elisa Kit
  • XenMLP Elisa Kit
  • Xmad3 Elisa Kit
  • XSmad3 Elisa Kit

Protein level used designations for SMAD3

MAD homolog 3 , MAD homolog 3a , MAD, mothers against decapentaplegic homolog 3 , SMA- and MAD-related protein 3 , SMAD, mothers against DPP homolog 3 , hMAD-3 , hSMAD3 , mad homolog JV15-2 , mad protein homolog , mad3 , mothers against DPP homolog 3 , mothers against decapentaplegic homolog 3 , SMAD 3 , TGF beta response effector Smad3 , TGF-beta response effector Smad3 , Smad 3 , mMad3 , MAD (mothers against decapentaplegic, Drosophila) homolog 3 , SMAD family member 3

GENE ID SPECIES
100033845 Equus caballus
58092 Danio rerio
100346303 Oryctolagus cuniculus
4088 Homo sapiens
378633 Xenopus laevis
395132 Gallus gallus
610902 Canis lupus familiaris
397260 Sus scrofa
17127 Mus musculus
25631 Rattus norvegicus
515125 Bos taurus
100731807 Cavia porcellus
443169 Ovis aries
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