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Browse our anti-TRF2 (TERF2) Antibodies

Full name:
anti-Telomeric Repeat Binding Factor 2 Antibodies (TERF2)
On are 73 Telomeric Repeat Binding Factor 2 (TERF2) Antibodies from 13 different suppliers available. Additionally we are shipping TRF2 Kits (9) and TRF2 Proteins (5) and many more products for this protein. A total of 94 TRF2 products are currently listed.
TERF2, TRBF2, trf2
list all antibodies Gene Name GeneID UniProt
TERF2 7014 Q15554
TERF2 21750 O35144
TERF2 361403  

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anti-Human TRF2 Antibodies:

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Top referenced anti-TRF2 Antibodies

  1. Human Polyclonal TRF2 Primary Antibody for DB, EIA - ABIN493534 : Bilaud, Brun, Ancelin, Koering, Laroche, Gilson: Telomeric localization of TRF2, a novel human telobox protein. in Nature genetics 1997 (PubMed)
    Show all 4 references for ABIN493534

  2. Human Polyclonal TRF2 Primary Antibody for DB, EIA - ABIN493530 : Broccoli, Smogorzewska, Chong, de Lange: Human telomeres contain two distinct Myb-related proteins, TRF1 and TRF2. in Nature genetics 1997 (PubMed)
    Show all 4 references for ABIN493530

  3. Human Polyclonal TRF2 Primary Antibody for DB, EIA - ABIN493532 : Khan, Yanez, Seldeen, Wang, Lindsay, Fletcher: Interactions of TRF2 with model telomeric ends. in Biochemical and biophysical research communications 2007 (PubMed)
    Show all 4 references for ABIN493532

  4. Human Polyclonal TRF2 Primary Antibody for IHC (p), WB - ABIN657781 : Prescott, McGrath, Lee, Buring, De Vivo: Telomere length and genetic analyses in population-based studies of endometrial cancer risk. in Cancer 2010 (PubMed)
    Show all 3 references for ABIN657781

  5. Human Monoclonal TRF2 Primary Antibody for IHC, ELISA - ABIN1724941 : Diehl, Idowu, Kimmelshue, York, Jackson-Cook, Turner, Holt, Elmore: Elevated TRF2 in advanced breast cancers with short telomeres. in Breast cancer research and treatment 2011 (PubMed)
    Show all 2 references for ABIN1724941

  6. Cow (Bovine) Polyclonal TRF2 Primary Antibody for WB - ABIN374265 : Ohbayashi, Kishimoto, Makino, Shimada, Nakadai, Aoki, Kawata, Niwa, Tamura: Isolation of cDNA, chromosome mapping, and expression of the human TBP-like protein. in Biochemical and biophysical research communications 1999 (PubMed)

  7. Cow (Bovine) Polyclonal TRF2 Primary Antibody for WB - ABIN2779306 : Etheridge, Compton, Barrientos, Ozgur, Griffith, Counter: Tethering telomeric double- and single-stranded DNA-binding proteins inhibits telomere elongation. in The Journal of biological chemistry 2008 (PubMed)

More Antibodies against TRF2 Interaction Partners

Human Telomeric Repeat Binding Factor 2 (TERF2) interaction partners

  1. TRF2 deficiency led to a 1,5-2 fold increase in the radiosensitivity of hMSC-telo1 (show ATM Antibodies) cells through telomere destabilization.

  2. DREEM imaging shows that in contrast to chromatin with DNA wrapping around histones, large TRF2-DNA complexes (with volumes larger than TRF2 tetramers) compact DNA inside TRF2 with portions of folded DNA appearing at the edge of these complexes.

  3. observed that the expression of Sp1 (show PSG1 Antibodies) is down-regulated in the TRF2(DeltaBDeltaM)-induced senescence, which was mediated by ATM (show ATM Antibodies) and p38 MAPK (show MAPK14 Antibodies)

  4. Data show that isoform beta2 of the heregulin (HRGbeta2) localizes at telomeres with the telomere-associated proteins TRF2 and RAP1.

  5. These observations suggest that TRF2 is a good candidate for the attachment of telomeres to the nuclear envelope in somatic cells

  6. Through a combination of biochemical, biophysical and structural approaches, we unveiled a unique mode of assembly between RAP1 (show RABGEF1 Antibodies) and TRF2

  7. that a dimer of the shelterin subunit TRF2 wraps approximately 90 bp of DNA through several lysine and arginine residues localized around its homodimerization domain.

  8. TRF2 overexpression results in replication stalling in duplex telomeric repeat tracts and formation of telomeric ultrafine anaphase bridges, ultimately leading to stochastic loss of telomeric sequences.

  9. APB (show RNPEP Antibodies) formation induced clustering of telomere repeats, telomere compaction and concomitant depletion of the shelterin protein TRF2 (also known as TERF2).

  10. Study demonstrates that TRF2 interacts with and is sumoylated by PIAS1 (show PIAS1 Antibodies) and RNF4 (show RNF4 Antibodies) targets SUMO-conjugated TRF2 for ubiquitination, thereby decreasing its stability suggesting that TRF2 status provides a molecular switch that controls its level at telomeres.

Mouse (Murine) Telomeric Repeat Binding Factor 2 (TERF2) interaction partners

  1. Overexpressing TRF2-S and silencing FMRP (show FMR1 Antibodies) promotes mRNA entry to axons and enhances axonal outgrowth and neurotransmitter release from presynaptic terminals.

  2. TRF2 binds and transactivates the promoter of the angiogenic tyrosine kinase (show TYRO3 Antibodies) platelet-derived growth factor receptor beta (show PDGFRB Antibodies) (PDGFRbeta).

  3. role of TRF2 in skin homeostasis, is reported.

  4. shelterin protein TIN2 (show TINF2 Antibodies) can protect chromosome ends as a TRF2-tethered TIN2 (show TINF2 Antibodies)/TPP1 (show TPP1 Antibodies)/POT1 (show POT1 Antibodies) complex that lacks a physical connection to TRF1 (show TERF1 Antibodies)

  5. We concluded that genomic instability resulting from loss of TRF2 expression provides biological advantages to the cancer stem cell population

  6. Conditional deletion of individual components of shelterin showed that TRF2 was required for the formation and/or maintenance of t-loops, whereas deletion of TRF1 (show TERF1 Antibodies), Rap1 (show TERF2IP Antibodies), or the POT1 (show POT1 Antibodies) proteins (POT1a (show POT1 Antibodies) and POT1b) had no effect on the frequency of t-loop occurrence.

  7. TAF7L (show TAF7L Antibodies) associates with TRF2 both in vitro and in testis, suggesting that TAF7L (show TAF7L Antibodies) likely cooperates directly with TRF2 at promoters of a subset of postmeiotic genes to regulate spermiogenesis.

  8. Experiments in cells from knockout mice showed that uPAR (show PLAUR Antibodies) controls the ubiquitin-proteasome system in VSMC & regulates doxorubicin-induced TRF2 ubiquitination and proteasomal degradation via this mechanism.

  9. the molecular properties of TRF2 that are both necessary and sufficient to protect chromosome ends in mouse embryonic fibroblasts: the data support a two-step mechanism for TRF2-mediated end protection

  10. TRF2 provides a crucial link between telomere function and ultraviolet-induced damage repair, whose alteration underlies genomic instability, cancer and aging.

TRF2 (TERF2) Antigen Profile

Antigen Summary

This gene encodes a telomere specific protein, TERF2, which is a component of the telomere nucleoprotein complex. This protein is present at telomeres in metaphase of the cell cycle, is a second negative regulator of telomere length and plays a key role in the protective activity of telomeres. While having similar telomere binding activity and domain organization, TERF2 differs from TERF1 in that its N terminus is basic rather than acidic.

Alternative names and synonyms associated with TRF2 (TERF2)

  • telomeric repeat binding factor 2 (TERF2) antibody
  • telomeric repeat binding factor 2 (Terf2) antibody
  • telomeric repeat binding factor 2 (terf2) antibody
  • TERF2 antibody
  • TRBF2 antibody
  • trf2 antibody

Protein level used designations for TERF2

telomeric repeat binding factor 2 , TTAGGG repeat-binding factor 2 , telomeric DNA-binding protein , telomeric repeat binding protein 2 , telomeric repeat-binding factor 2 , TTAGGG-repeat binding factor 2 TRF2 , telomeric repeat binding factor a , TTAGGG repeat binding factor 2

454201 Pan troglodytes
704879 Macaca mulatta
100028044 Monodelphis domestica
7014 Homo sapiens
21750 Mus musculus
361403 Rattus norvegicus
489736 Canis lupus familiaris
395598 Gallus gallus
734203 Xenopus laevis
506501 Bos taurus
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