Browse our Glutaredoxin 5 Proteins (GLRX5)

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Glutaredoxin 5 Proteins (GLRX5)
On are 11 Glutaredoxin 5 (GLRX5) Proteins from 5 different suppliers available. Additionally we are shipping Glutaredoxin 5 Antibodies (41) and Glutaredoxin 5 Kits (1) and many more products for this protein. A total of 56 Glutaredoxin 5 products are currently listed.
2310004O13Rik, 2900070E19Rik, AU020725, C14orf87, FLB4739, GRX5, id:ibd5119, PR01238, PRO1238, RGD1308383, wu:fa09g08, zgc:73343
list all proteins Gene Name GeneID UniProt
GLRX5 51218 Q86SX6
Rat GLRX5 GLRX5 362776  
GLRX5 73046 Q80Y14

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Glutaredoxin 5 Proteins (GLRX5) by Origin

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Top referenced Glutaredoxin 5 Proteins

  1. Human GLRX5 Protein expressed in Escherichia coli (E. coli) - ABIN666987 : Holmgren: Thioredoxin and glutaredoxin: small multi-functional redox proteins with active-site disulphide bonds. in Biochemical Society transactions 1988 (PubMed)
    Show all 2 references for 666987

More Proteins for Glutaredoxin 5 Interaction Partners

Human Glutaredoxin 5 (GLRX5) interaction partners

  1. Patients with GLRX5-associated variant nonketotic hyperglycemia had normal development with childhood-onset spastic paraplegia, spinal lesion, and optic atrophy.

  2. crystal structure of GLRX5 revealed a tetrameric organization with the [2Fe-2S] clusters buried in the interior and shielded from the solvent by the conserved beta1-alpha2 loop

  3. Glutaredoxin 5 deficiency causes sideroblastic anemia by specifically impairing heme biosynthesis and depleting cytosolic iron in human erythroblasts

  4. No GLRX5 mutations were found among sixty CSA probands examined

  5. Mutations in GLRX5 is associated with sideroblastic-like microcytic anemia and iron overload

Mouse (Murine) Glutaredoxin 5 (GLRX5) interaction partners

  1. Study reports a decrease of Grx (show GRX1 Proteins) expression levels in pancreatic islets of diabetic mice which was accompanied by declining insulin (show INS Proteins) secretion, increase of reactive oxygen species (ROS (show ROS1 Proteins)) production level, and cell cycle alterations. These data demonstrate the essential role of the Grx (show GRX1 Proteins) system for the beta-cell during metabolic stress which may provide a new target for diabetes mellitus type 2 treatment.

  2. Grx5 is an important determinant of osteoblast apoptosis and acts via a molecular pathway that involves regulation of ROS (show ROS1 Proteins) production, cardiolipin oxidation, caspase (show CASP3 Proteins) activity, Fe-S cluster formation, and MnSOD (show SOD2 Proteins) activity.

Zebrafish Glutaredoxin 5 (GLRX5) interaction partners

  1. the hypochromic anaemia in shiraz (sir) zebrafish mutants is caused by deficiency of glutaredoxin 5 (grx5), a gene required in yeast for Fe-S cluster assembly

Glutaredoxin 5 (GLRX5) Protein Profile

Protein Summary

This gene encodes a mitochondrial protein, which is evolutionarily conserved. It is involved in the biogenesis of iron-sulfur clusters, which are required for normal iron homeostasis. Mutations in this gene are associated with autosomal recessive pyridoxine-refractory sideroblastic anemia.

Alternative names and synonyms associated with Glutaredoxin 5 (GLRX5)

  • glutaredoxin 5 (glrx5)
  • glutaredoxin 5 (GLRX5)
  • glutaredoxin 5 (Glrx5)
  • glutaredoxin 5 homolog (S. cerevisiae) (Glrx5)
  • glutaredoxin 5 homolog (S. cerevisiae) (glrx5)
  • 2310004O13Rik protein
  • 2900070E19Rik protein
  • AU020725 protein
  • C14orf87 protein
  • FLB4739 protein
  • GRX5 protein
  • id:ibd5119 protein
  • PR01238 protein
  • PRO1238 protein
  • RGD1308383 protein
  • wu:fa09g08 protein
  • zgc:73343 protein

Protein level used designations for Glutaredoxin 5 Proteins (GLRX5)

glutaredoxin 5 homolog , glutaredoxin-related protein 5, mitochondrial , monothiol glutaredoxin-5 , shiraz , shz

734675 Xenopus laevis
51218 Homo sapiens
505935 Bos taurus
362776 Rattus norvegicus
73046 Mus musculus
406294 Danio rerio
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