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Browse our CXCL2 Proteins (CXCL2)

Full name:
Chemokine (C-X-C Motif) Ligand 2 Proteins (CXCL2)
On are 98 Chemokine (C-X-C Motif) Ligand 2 (CXCL2) Proteins from 18 different suppliers available. Additionally we are shipping CXCL2 Antibodies (134) and CXCL2 Kits (108) and many more products for this protein. A total of 345 CXCL2 products are currently listed.
CDW2, CINC-2a, GID7, Gro2, GRO3, GROB, GROX, Mgsa-b, MIP-2, MIP-2a, MIP-2alpha, Mip2, MIP2A, Scyb, SCYB2
list all proteins Gene Name GeneID UniProt
CXCL2 114105 P30348
CXCL2 2920 P19875
CXCL2 20310 P10889

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CXCL2 Proteins (CXCL2) by Origin

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Top referenced CXCL2 Proteins

  1. Human CXCL2 Protein expressed in Escherichia coli (E. coli) - ABIN2666640 : Carlson, Kroenke, Rao, Lane, Segal: The Th17-ELR+ CXC chemokine pathway is essential for the development of central nervous system autoimmune disease. in The Journal of experimental medicine 2008 (PubMed)
    Show all 6 references for ABIN2666640

  2. Mouse (Murine) CXCL2 Protein expressed in Escherichia coli (E. coli) - ABIN2666642 : Haskill, Peace, Morris, Sporn, Anisowicz, Lee, Smith, Martin, Ralph, Sager: Identification of three related human GRO genes encoding cytokine functions. in Proceedings of the National Academy of Sciences of the United States of America 1990 (PubMed)
    Show all 6 references for ABIN2666642

  3. Human CXCL2 Protein expressed in Escherichia coli (E. coli) - ABIN666759 : Jerva, Sullivan, Lolis: Functional and receptor binding characterization of recombinant murine macrophage inflammatory protein 2: sequence analysis and mutagenesis identify receptor binding epitopes. in Protein science : a publication of the Protein Society 1997 (PubMed)
    Show all 3 references for ABIN666759

  4. Human CXCL2 Protein expressed in Wheat germ - ABIN1350823 : Nikolakopoulou, Dutta, Chen, Miller, Trapp: Activated microglia enhance neurogenesis via trypsinogen secretion. in Proceedings of the National Academy of Sciences of the United States of America 2013 (PubMed)

  5. Mouse (Murine) CXCL2 Protein expressed in Escherichia coli (E. coli) - ABIN2007271 : De Plaen, Han, Liu, Hsueh, Ghosh, May: Lipopolysaccharide induces CXCL2/macrophage inflammatory protein-2 gene expression in enterocytes via NF-kappaB activation: independence from endogenous TNF-alpha and platelet-activating factor. in Immunology 2006 (PubMed)

  6. Mouse (Murine) CXCL2 Protein expressed in Escherichia coli (E. coli) - ABIN1046726 : Wolpe, Sherry, Juers, Davatelis, Yurt, Cerami: Identification and characterization of macrophage inflammatory protein 2. in Proceedings of the National Academy of Sciences of the United States of America 1989 (PubMed)

More Proteins for CXCL2 Interaction Partners

Horse (Equine) Chemokine (C-X-C Motif) Ligand 2 (CXCL2) interaction partners

  1. Results suggested that chemokine (show CCL1 Proteins) expression by cultured equine BECs following exposure to pulmonary hemorrhage conditions may contribute to the development of inflammatory airway disease in horses.

  2. This study examined effects of in vitro exposure to solutions of hay (show GTF2H5 Proteins) dust, lipopolysaccharides, or beta-glucan on cytokine expression in pulmonary mononuclear cells isolated from healthy horses and horses with recurrent airway obstruction.

Human Chemokine (C-X-C Motif) Ligand 2 (CXCL2) interaction partners

  1. Results identify the CXCL2/MIF (show AMH Proteins)-CXCR2 (show CXCR2 Proteins) axis as an important mediator in MDSC recruitment and as predictors in bladder cancer.

  2. Chronic inflammation contributes to the change of CXCL12 (show CXCL12 Proteins) DNA methylation (show HELLS Proteins) in buccal cells and that DNA methylation (show HELLS Proteins) profile of CXCL12 (show CXCL12 Proteins) promoter plays important role in development and progression of periodontal disease.

  3. WDR26 (show WDR26 Proteins) serves as a scaffold that fosters assembly of a specific signaling complex consisting of Gbetagamma, PI3Kbeta and AKT2 (show AKT2 Proteins) in breast cancer.

  4. Polymorphisms in the promoter regions of the CXCL1 (show CXCL1 Proteins) and CXCL2 genes contribute to increased risk of alopecia areata in the Korean population

  5. The WDR26 (show WDR26 Proteins) gene was differentially methylated in monozygotic twins discordant for depressive disorder.

  6. In this review, a genetic variant in CXCL12 (show CXCL12 Proteins) is described that is associated with type 2 diabetes mellitus and its complications.

  7. We have demonstrated that GRObeta, as an oncogene (show RAB1A Proteins) product, contributed to tumorigenesis and metastasis of HCC (show FAM126A Proteins)

  8. Our results demonstrated that resistance to anti-proliferative effects of CXCR2 (show CXCR2 Proteins) may also arise from feedback increases in MIP-2 secretion.

  9. autophagy is required for Hepatitis B virus-induced NF-kappaB (show NFKB1 Proteins) activation and release of IL-6 (show IL6 Proteins), IL-8 (show IL8 Proteins), and CXCL2 in Hepatocytes

  10. The results link CXCL1 (show CXCL1 Proteins) and CXCL2 chemokines with bone marrow adiposity and implicate CXCR2 (show CXCR2 Proteins) signaling in promoting effects of marrow fat on progression of skeletal tumors in bone.

Mouse (Murine) Chemokine (C-X-C Motif) Ligand 2 (CXCL2) interaction partners

  1. p53 (show TP53 Proteins)-mediated induction of PAI-1 (show SERPINE1 Proteins) expression due to chronic CS exposure exacerbates lung inflammation through elaboration of CXCL1 (show CXCL1 Proteins), CXCL2, and CXCR2 (show CXCR2 Proteins).

  2. Social defeat induced an exposure-dependent increase in mRNA levels of E-selectin (show SELE Proteins), CXCL1 (show CXCL1 Proteins), and CXCL2 that increased with additional days of social defeat.

  3. MIP-2 directly impairs neonatal pulmonary endothelial cell migration in vitro.

  4. These results have suggested that the activation of MyD88 (show MYD88 Proteins) pathway by constitutive low-level IL-1beta (show IL1B Proteins) expression is essential for pressure force-induced CXCL2 and CCL2 (show CCL2 Proteins) expression in osteoblasts.

  5. SIRT2 (show SIRT2 Proteins) regulates LPS (show TLR4 Proteins) induced proximal renal tubules CXCL2 protein expression.

  6. miR26a/-26b-COX-2-MIP-2 loop regulates allergic inflammation and the feedback relationship between allergic inflammation and the enhanced tumorigenic and metastatic potential

  7. huH1N1 virus PA and NA mediated increased MIP-2 expression early postinfection, resulting in substantial pulmonary neutrophilia with enhanced lung pathology and disease

  8. Syndecan-1 (show SDC1 Proteins) is expressed in the parietal peritoneum microvasculature but does not regulate leukocyte recruitment and is not necessary for the presentation of the chemokine (show CCL1 Proteins) MIP-2 in this tissue.

  9. Identified TLR2 and S100A8 (show S100A8 Proteins)/S100A9 (show S100A9 Proteins) as key regulators of hepatic CXCL-2 expression and neutrophil recruitment.

  10. Suggest anti-inflammatory action of daidzein in lung epithelial cells is mediated via a direct interaction with PARP-1 (show PARP1 Proteins), which inhibits RelA/p65 (show NFkBP65 Proteins) protein PARylation required for the transcriptional modulation of pro-inflammatory chemokines such as Cxcl2.

Pig (Porcine) Chemokine (C-X-C Motif) Ligand 2 (CXCL2) interaction partners

  1. reports transmural and perivascular expression patterns of chemokines CCL2 (show CCL2 Proteins) and CXCL2 and of chemokine (show CCL1 Proteins) receptors CCR2 (show CCR2 Proteins), CCR5, and CXCR4 (show CXCR4 Proteins) following coronary angioplasty

CXCL2 Protein Profile

Protein Summary

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Two transcript variants encoding two different isoforms have been found for this gene.

Alternative names and synonyms associated with CXCL2

  • chemokine (C-X-C motif) ligand 2 (CXCL2)
  • chemokine (C-X-C motif) ligand 2 (Cxcl2)
  • WD repeat domain 26 (WDR26)
  • CDW2 protein
  • CINC-2a protein
  • GID7 protein
  • Gro2 protein
  • GRO3 protein
  • GROB protein
  • GROX protein
  • Mgsa-b protein
  • MIP-2 protein
  • MIP-2a protein
  • MIP-2alpha protein
  • Mip2 protein
  • MIP2A protein
  • Scyb protein
  • SCYB2 protein

Protein level used designations for CXCL2

GRO-gamma , GRO3 oncogene , GRO3, growth related gene 3 , growth-regulated protein homolog gamma , C-X-C motif chemokine 2 , CINC-3 , MIP2 , cytokine-induced neutrophil chemoattractant 3 , macrophage inflammatory protein 2 , small inducible cytokine subfamily, member 2 , GRO2 oncogene , MGSA beta , MIP2-alpha , gro-beta , growth-regulated protein beta , macrophage inflammatory protein 2-alpha , melanoma growth stimulatory activity beta , chemokine ligand 2 , GRO-beta , GRO2, growth related gene 2 (GRO2 oncogene) , growth related oncogene X , growth-regulated protein homolog beta , CUL4- and DDB1-associated WDR protein 2 , GID complex subunit 7 homolog , WD repeat-containing protein 26 , myocardial ischemic preconditioning up-regulated protein 2 , myocardial ischemic preconditioning upregulated protein 2

281214 Bos taurus
100233237 Equus caballus
114105 Rattus norvegicus
2920 Homo sapiens
20310 Mus musculus
414904 Sus scrofa
281734 Bos taurus
80232 Homo sapiens
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