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identify PDL1 (show CD274 Proteins) and MUM1 (show IRF4 Proteins) as prognostic biomarkers for high-risk disease in primary mediastinal large B-cell lymphoma
MUM-1 (show IRF4 Proteins) could be a useful marker for the differential diagnosis of angioimmunoblastic T cell lymphoma (AITL) with Hodgkin/Reed-Sternberg like cells and classical Hodgkins lymphoma.
MUM1 (show IRF4 Proteins) expression is reliable in the prognosis of diffuse large B-cell lymphoma.
These results show that MUM1 (show IRF4 Proteins) is a strong and robust predictive immunohistochemical marker in patients with follicular lymphoma
The study demonstrated differential MUM-1 (show IRF4 Proteins) expression between PEComas and other true melanocytic tumors
Mum-1 (show IRF4 Proteins) was positive in all but one case (96.7%) of systemic anaplastic large-cell lymphoma by tissue microarray immunohistochem analysis.
expression of CARMA1 (show CARD11 Proteins) mRNA is likely associated with the expression of MUM1 (show IRF4 Proteins) and shows male predominance in diffuse large B cell lymphoma.
Data show that BCL-6 (show BCL6 Proteins) (64%) and MUM1 (show IRF4 Proteins) (45%) were expressed in patients with primary mediastinal large B-cell lymphoma.
report the identification of the PWWP domain-containing protein EXPAND1/MUM1 as an architectural component of the chromatin, which in response to DNA damage serves as an accessory factor to promote cell survival.
results suggest that MUM1 plays roles in the progression of B-cell lymphoma/leukemia by regulating the expression of various genes including MIG (show CXCL9 Proteins).
Involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. Required for efficient DNA repair and cell survival following DNA damage (By similarity).
PWWP domain-containing protein MUM1
, melanoma ubiquitous mutated protein
, mutated melanoma-associated antigen 1
, protein expandere
, interferon regulatory factor 4