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Browse our C1QC Proteins (C1QC)

Full name:
Complement Component 1, Q Subcomponent, C Chain Proteins (C1QC)
On are 4 Complement Component 1, Q Subcomponent, C Chain (C1QC) Proteins from 3 different suppliers available. Additionally we are shipping C1QC Antibodies (51) and C1QC Kits (15) and many more products for this protein. A total of 78 C1QC products are currently listed.
AI385742, C1Q-C, c1qc, C1QG, Ciqc
list all proteins Gene Name GeneID UniProt
C1QC 12262 Q02105
C1QC 362634 P31722
C1QC 714 P02747

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More Proteins for C1QC Interaction Partners

Mouse (Murine) Complement Component 1, Q Subcomponent, C Chain (C1QC) interaction partners

Human Complement Component 1, Q Subcomponent, C Chain (C1QC) interaction partners

  1. Neuromyelitis optica patients had higher levels of C3a (show C3 Proteins) and anti-C1q antibodies than healthy controls.

  2. Data indicate that Cna binds to C1q.

  3. Analysis of its interaction properties by surface plasmon resonance shows that rC1q retains the ability of serum C1q to associate with the C1s (show C1S Proteins)-C1r-C1r (show C1R Proteins)-C1s (show C1S Proteins) tetramer, to recognize physiological C1q ligands such as IgG and pentraxin 3 (show PTX3 Proteins)

  4. Single nucleotide polymorphisms in and around the C1q genes, C1qA (show C1QA Proteins), C1qB (show C1QB Proteins) and C1qC, correlated with C1q serum levels and may be a risk for the development of rheumatoid arthritis.

  5. Three single nucleotide polymorphisms (STAT6 (show STAT6 Proteins) rs703817, C1qG rs17433222, and MBP (show MBL2 Proteins) rs3794845) were found to be significantly associated with childhood leukemia risk in Koreans.

  6. These results suggest a novel pathway in which C1q and MBL influence removal and metabolism of atherogenic forms of LDL in the early stages of atherosclerosis.

  7. Data show that C1q, C4, C3, and C9 bind to thrombin receptor (show F2R Proteins)-activating peptide-activated platelets in lepirudin-anticoagulated platelet-rich plasma (PRP (show C4BPA Proteins)) and whole blood.

  8. Experiments with recombinant globular head domains of human C1q A, B, and C chains indicated that C1q interacts with PTX3 (show PITX3 Proteins) via its globular head region. Binding of C1q to immobilized PTX3 (show PITX3 Proteins) induced activation of the classical complement pathway.

  9. The C-terminal globular region of the C1Q C chain may have evolved as a functionally specialized domain or module with distinct binding properties which together with the A and B chains confers versatility and flexibility to the whole C1q molecule.

  10. The structure refined to 1.9 A of resolution of C1q reveals the conformation of subunits A, B, and C and their compact, almost spherical heterotrimeric assembly held together mainly by non-polar interactions, with a Ca2 (show CA2 Proteins)+ ion bound at the top.

C1QC Protein Profile

Protein Summary

This gene encodes a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. A deficiency in C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N-terminus, and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. This gene encodes the C-chain polypeptide of human complement subcomponent C1q. Alternatively spliced transcript variants that encode the same protein have been found for this gene.

Alternative names and synonyms associated with C1QC

  • complement component 1, q subcomponent, C chain (C1QC)
  • Complement C1q subcomponent subunit C (c1qc)
  • complement component 1, q subcomponent, C chain (C1qc)
  • AI385742 protein
  • C1Q-C protein
  • c1qc protein
  • C1QG protein
  • Ciqc protein

Protein level used designations for C1QC

complement component 1, q subcomponent, C chain , complement C1q subcomponent subunit C , Complement C1q subcomponent subunit C , complement component 1, q subcomponent, c polypeptide , complement component 1, q subcomponent, gamma polypeptide

419503 Gallus gallus
487382 Canis lupus familiaris
509968 Bos taurus
100196757 Salmo salar
12262 Mus musculus
362634 Rattus norvegicus
714 Homo sapiens
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