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Browse our anti-C1S (C1S) Antibodies

Full name:
anti-Complement Component 1, S Subcomponent Antibodies (C1S)
On www.antibodies-online.com are 70 Complement Component 1, S Subcomponent (C1S) Antibodies from 20 different suppliers available. Additionally we are shipping C1S Kits (13) and C1S Proteins (11) and many more products for this protein. A total of 99 C1S products are currently listed.
Synonyms:
AA959438, AI255193, AI327365, C1S, C1sa, r-gsp

All available anti-C1S Antibodies

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Top referenced anti-C1S Antibodies

  1. Human Monoclonal C1S Primary Antibody for Func, EIA - ABIN1105612 : Nakagawa, Sakiyama, Tsuchida, Yamaguchi, Toyoguchi, Masuda, Moriya: Complement C1s activation in degenerating articular cartilage of rheumatoid arthritis patients: immunohistochemical studies with an active form specific antibody. in Annals of the rheumatic diseases 1999 (PubMed)
    Show all 2 references for ABIN1105612

  2. Human Polyclonal C1S Primary Antibody for IHC, ELISA - ABIN1534794 : Tosi, Duponchel, Meo, Julier: Complete cDNA sequence of human complement Cls and close physical linkage of the homologous genes Cls and Clr. in Biochemistry 1988 (PubMed)

More Antibodies against C1S Interaction Partners

Human Complement Component 1, S Subcomponent (C1S) interaction partners

  1. C1q exists as the C1 complex (C1qC1r2C1s2), and C1q binding to ligands activates the C1r (show C1R Antibodies)/C1s proteases. Incubation of nucleoli with C1 caused degradation of the nucleolar proteins nucleolin (show NCL Antibodies) and nucleophosmin 1 (show NPM1 Antibodies). T

  2. Data indicate that complement C1s mRNA level was low in ICR-derived glomerulonephritis (ICGN) mice liver as compared with age-matched ICR mice.

  3. Analysis of its interaction properties by surface plasmon resonance shows that rC1q retains the ability of serum C1q to associate with the C1s-C1r-C1r (show C1R Antibodies)-C1s tetramer, to recognize physiological C1q ligands such as IgG and pentraxin 3 (show PTX3 Antibodies)

  4. A molecular switch governs the interaction between the human complement protease C1s and its substrate, complement C4 (show C4A Antibodies).

  5. Four positively charged amino acids on the serine protease (show F2 Antibodies) domain appear to form a catalytic exosite that is required for efficient cleavage of C4 in the classical pathway of complement.

  6. These results provide further structural insights into the architecture of the C1 complex, and the interactions between C1r (show C1R Antibodies) and C1s.

  7. Detailed mapping of post-translational modifications and insights into the C1r (show C1R Antibodies)/C1s binding sites.

  8. Interaction with the prime side residues at the cleavage point in C1s enhances the affinity of the enzyme for complement 2 and complement 4 substrates; these prime subsite residues mediate positive cooperativity in the cleavage of the substrate.

  9. There are splice variants of C1s mRNA transcripts in normal human cells

Mouse (Murine) Complement Component 1, S Subcomponent (C1S) interaction partners

  1. C1r and this gene are duplicated in mice; differential expression generates alternative isomorphs in the liver and in the male reproductive system.

C1S Antigen Profile

Antigen Summary

This gene encodes a serine protease, which is a major constituent of the human complement subcomponent C1. C1s associates with two other complement components C1r and C1q in order to yield the first component of the serum complement system. Defects in this gene are the cause of selective C1s deficiency.

Alternative names and synonyms associated with C1S

  • complement component 1, s subcomponent (C1S) antibody
  • complement component 1, s subcomponent (c1s) antibody
  • complement component 1, s subcomponent (LOC100222051) antibody
  • complement component 1, s subcomponent (C1s) antibody
  • AA959438 antibody
  • AI255193 antibody
  • AI327365 antibody
  • C1S antibody
  • C1sa antibody
  • r-gsp antibody

Protein level used designations for C1S

C1 esterase , complement C1s subcomponent , complement component 1 subcomponent s , complement component C1s , complement component 1, s subcomponent , complement C1s subcomponent-like , basic proline-rich peptide IB-1 , complement C1s-A subcomponent , complement component 1 subcomponent s-A , complement component C1SA , serine protease

GENE ID SPECIES
397274 Sus scrofa
418294 Gallus gallus
451808 Pan troglodytes
613055 Xenopus (Silurana) tropicalis
714589 Macaca mulatta
722136 Macaca mulatta
733422 Xenopus laevis
100222051 Taeniopygia guttata
100412274 Callithrix jacchus
100455685 Pongo abelii
100549400 Meleagris gallopavo
100558615 Anolis carolinensis
100599399 Nomascus leucogenys
716 Homo sapiens
192262 Rattus norvegicus
767827 Bos taurus
486714 Canis lupus familiaris
50908 Mus musculus
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