Browse our C4B Proteins (C4B)

Full name:
Complement Component 4B Proteins (C4B)
On are 8 Complement Component 4B (C4B) Proteins from 3 different suppliers available. Additionally we are shipping C4B Antibodies (98) and C4B Kits (41) and many more products for this protein. A total of 147 C4B products are currently listed.
C4, C4B, C4B1, C4B2, C4B3, C4B5, C4B12, C4BD, C4B_2, C4F, CH, CO4, CPAMD3, DKFZP469I0332, Ss, wu:fi14a03
list all proteins Gene Name GeneID UniProt
C4B 12268 P01029
C4B 721 P0C0L4 , P0C0L5

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C4B Proteins (C4B) by Origin

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More Proteins for C4B Interaction Partners

Mouse (Murine) Complement Component 4B (C4B) interaction partners

  1. C4 mediated synapse elimination during postnatal development

  2. Data indicate complement C3 (show C3 Proteins) deposition on peanut extract (PE) was abolished in immunoglobulin- and C4-deficient sera.

  3. a deficiency in C4b does not alter radiation-induced lung disease in the C57BL/6 mouse model

  4. C3 and C4 bind to collagen and elastin (show ELN Proteins) in the vascular wall and have a potential role in vascular stiffness and atherosclerosis

  5. Complement C4 provides an important protective role against the development of systemic lupus erythematosus.

  6. identified the murine follicular dendritic cell marker, FDC-M2, as complement c4. FDC-M2 was detectable at sites of immune complex-mediated inflammatory disease

  7. The increased mortality of C4(-/-) or Factor B (show CFB Proteins)(-/-) mice indicates that these two pathways of complement activation are required for survival in mousepox.

  8. Increased transcription of the complement C4 gene in the Rag1 (show RAG1 Proteins)(-/-) intestine.

Human Complement Component 4B (C4B) interaction partners

  1. The structural basis for inhibition of the classical and lectin complement pathways by S. aureus extracellular adherence protein binding to C4b has been presented.

  2. The aims of this study were to elucidate the copy number variations of C4A and C4B in relation to disease risk in systemic lupus erythematosus, and to compare the basis of race-specific C4A deficiency between East Asians and individuals of European descent

  3. C4A and C4B gene copy numbers are stronger risk factors for juvenile-onset than for adult-onset systemic lupus erythematosus

  4. Data indicate Ig-like transcript 4 (ILT4 (show LILRB2 Proteins)) as a cellular receptor for complement split products (CSPs) complement component 4d (C4d).

  5. Suggest a prominent prognostic value of C4d staining as a rejection marker in ABO compatible kidney transplantation.

  6. The interaction between C4BP (show C4BPA Proteins) and Leptospira interrogans LcpA, LigA and LigB is sensitive to ionic strength and inhibited by heparin.

  7. Schizophrenia risk from complex variation of complement component 4

  8. There was a significant association between C4d deposition on allograft endothelial cells and presence of class II DSA I chronic liver allograft failure.

  9. Carrying no copies of C4B significantly increases the risk of cCSC, whereas carrying three C4B copies is protective.

  10. our study indicates that Finnish NTM (show NTM Proteins) patients had significantly more often C4 deficiencies than the healthy control subjects.

C4B Protein Profile

Protein Summary

This gene encodes the basic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene. In addition, this gene exists as a long form and a short form due to the presence or absence of a 6.4 kb endogenous HERV-K retrovirus in intron 9.

Alternative names and synonyms associated with C4B

  • complement component 4A (Rodgers blood group) (C4A)
  • complement component 4 (c4)
  • complement component 4B (Chido blood group) (C4B)
  • complement component 4B (Chido blood group) (C4b)
  • C4 protein
  • C4B protein
  • C4B1 protein
  • C4B2 protein
  • C4B3 protein
  • C4B5 protein
  • C4B12 protein
  • C4BD protein
  • C4B_2 protein
  • C4F protein
  • CH protein
  • CO4 protein
  • CPAMD3 protein
  • DKFZP469I0332 protein
  • Ss protein
  • wu:fi14a03 protein

Protein level used designations for Complement Component 4B Proteins (C4B)

complement component 4B (Chido blood group) , complement component 4A , complement component 4B , complement C4-B , complement component 4 (within H-2S) , complement component 4B (Childo blood group) , C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3 , Chido form of C4 , basic complement C4 , complement C4B1a

462577 Pan troglodytes
566261 Danio rerio
100171517 Pongo abelii
12268 Mus musculus
721 Homo sapiens
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