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Browse our Kallikrein 12 Proteins (KLK12)

Full name:
Kallikrein-Related Peptidase 12 Proteins (KLK12)
On www.antibodies-online.com are 2 Kallikrein-Related Peptidase 12 (KLK12) Proteins from 2 different suppliers available. Additionally we are shipping Kallikrein 12 Antibodies (39) and Kallikrein 12 Kits (6) and many more products for this protein. A total of 51 Kallikrein 12 products are currently listed.
Synonyms:
2310008B01Rik, AI324852, KLK-L5, KLK12, KLKL5
list all proteins Gene Name GeneID UniProt
Mouse KLK12 KLK12 69511  
Rat KLK12 KLK12 308564  
KLK12 43849 Q9UKR0

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Kallikrein 12 Proteins (KLK12) by Origin

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More Proteins for Kallikrein 12 Interaction Partners

Human Kallikrein-Related Peptidase 12 (KLK12) interaction partners

  1. Data indicate that the KLK12 SNP rs3865443 was not associated with tumor aggressiveness but showed marginal association with prostate cancer risk for the rare homozygote.

  2. KLK12 gene is markedly overexpressed in gastric cancer

  3. Kallikrein 5 (show KLK5 Proteins) and kallikrein 12 cleave human influenza hemagglutinins and activate thrombolytic zymogens.

  4. the proangiogenic activity of KLK12 in lung endothelial cells was not related to a kinin release

  5. Results suggest that kallikrein-related peptidase 12 (KLK12) splice variant KLK12sv3 can be regarded as a marker of good prognosis in breast cancer.

  6. Serine protease (show F2 Proteins) of Kazal-type (SPINK6 (show SPINK6 Proteins)) expressed in normal human skin is a potent natural inhibitor of Kallikrein (show KLK4 Proteins)-related peptidases, KLK12 and KLK13 (show KLK13 Proteins).

  7. KLK12 may indirectly regulate the bioavailability and activity of several growth factors through processing of their CCN binding partners

  8. 4 types of polymorphisms were found in Japanese gastric cancer: 1 at an intron 4 splice-donor site (c.457+2T>C), 2 in exon 6 (c.618_619delTG:p.Cys206fsX72 & c.735G>A:p.Met245Ile), & 1 in intron 3. c.457+2C/C has no hK12 serine protease (show F2 Proteins) expression.

  9. KLK12 has trypsin-like activity, cleaving peptide bonds after both arginine & lysine. It quickly loses its activity due to autodegradation, its activity can also be rapidly inhibited by zinc ions & by alpha2-antiplasmin through covalent complex formation.

Kallikrein 12 (KLK12) Protein Profile

Protein Summary

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing of this gene results in three transcript variants encoding different isoforms.

Alternative names and synonyms associated with Kallikrein 12 (KLK12)

  • kallikrein-related peptidase 12 (KLK12)
  • kallikrein related-peptidase 12 (Klk12)
  • 2310008B01Rik protein
  • AI324852 protein
  • KLK-L5 protein
  • KLK12 protein
  • KLKL5 protein

Protein level used designations for KLK12

kallikrein-related peptidase 12 , kallikrein 12 , kallikrein-12 , kallikrein-like protein 5

GENE ID SPECIES
611766 Canis lupus familiaris
69511 Mus musculus
308564 Rattus norvegicus
43849 Homo sapiens
618448 Bos taurus
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