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Browse our Kallikrein 2 Proteins (KLK2)

Full name:
Kallikrein 2 Proteins (KLK2)
On www.antibodies-online.com are 5 Kallikrein 2 (KLK2) Proteins from 3 different suppliers available. Additionally we are shipping Kallikrein 2 Antibodies (77) and Kallikrein 2 Kits (26) and many more products for this protein. A total of 116 Kallikrein 2 products are currently listed.
Synonyms:
hGK-1, hK2, KAL, KALA, Klk1, KLK2, KLK2A2, Klk5, RATKALA, rGK-2, Ton
list all proteins Gene Name GeneID UniProt
Rat KLK2 KLK2 24841 P00759
KLK2 3817 P20151

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Kallikrein 2 Proteins (KLK2) by Origin

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More Proteins for Kallikrein 2 Interaction Partners

Human Kallikrein 2 (KLK2) interaction partners

  1. glycosylation changes the enzymatic activity of KLK2 in a drastically substrate-dependent manner.

  2. The results indicated that W-hK2 (show HK2 Proteins) had a defect in cellular trafficking due to its misfolding and that it activated the unfolded protein response, suggesting a mechanism to explain the association of the T allele with higher prostate cancer risk.

  3. miR (show MLXIP Proteins)-378 was predicted to target both KLK2 and KLK4 (show KLK4 Proteins) and downregulated levels detected in prostate cancer patients.

  4. The differential regulation of alternative transcripts (using KLK2, KLK3 (show KLKB1 Proteins) and KLK4 (show KLK4 Proteins) as models) by androgens and anti-androgens as an indicator of prostate cancers, was investigated.

  5. Structure-function analyses of KLK2 establish the 99-loop as master regulator of its activity.

  6. Predictions based on levels of four kallikrein (show KLK4 Proteins) markers, including KLK2, in blood distinguish between pathologically insignificant and aggressive disease after radical prostatectomy with good accuracy.

  7. Alteration of cellular junctions in benign prostatic hyperplasia could contribute to the presence of luminal epithelial secreted proteins prostate specific antigen (PSA (show KLK3 Proteins))2 and and KLK2 in the stromal compartment.

  8. we present the first evidence that KLK2 can also function as an androgen receptor (show AR Proteins) modulator that may modulate cell growth after the development of castration-resistant prostate cancer

  9. Associations observed in young, healthy men between the seminal plasma and serum concentrations of hK2 (show HK2 Proteins) and PSA (show PLAG1 Proteins) and several genetic variants in KLK2 and KLK3 (show KLKB1 Proteins) could be useful to refine models of PSA (show PLAG1 Proteins) cutoff values in prostate cancer testing.

  10. Genetic variants at ATF7IP and KLK2 contribute to the variance of %fPSA.

Kallikrein 2 (KLK2) Protein Profile

Protein Summary

This gene encodes a member of the grandular kallikrein protein family. Kallikreins are a subgroup of serine proteases that are clustered on chromosome 19. Members of this family are involved in a diverse array of biological functions. The protein encoded by this gene is a highly active trypsin-like serine protease that selectively cleaves at arginine residues. This protein is primarily expressed in prostatic tissue and is responsible for cleaving pro-prostate-specific antigen into its enzymatically active form. This gene is highly expressed in prostate tumor cells and may be a prognostic maker for prostate cancer risk. Alternate splicing results in both coding and non-coding transcript variants.

Alternative names and synonyms associated with Kallikrein 2 (KLK2)

  • kallikrein-related peptidase 2 (KLK2)
  • kallikrein 1-related peptidase C2 (Klk1c2)
  • kallikrein 5-like (Klk5l)
  • hGK-1 protein
  • hK2 protein
  • KAL protein
  • KALA protein
  • Klk1 protein
  • KLK2 protein
  • KLK2A2 protein
  • Klk5 protein
  • RATKALA protein
  • rGK-2 protein
  • Ton protein

Protein level used designations for Kallikrein 2 Proteins (KLK2)

kallikrein 2, prostatic , RSKG-5 , S2 kallikrein , esterase 1 , glandular kallikrein-2 , tonin , Kallikrein 1 renal/pancreas/salivary , kallikrein 5 , glandular kallikrein 2 , glandular kallikrein-1 , kallikrein-2 , tissue kallikrein-2

GENE ID SPECIES
748637 Pan troglodytes
24841 Rattus norvegicus
408211 Rattus norvegicus
3817 Homo sapiens
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