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Browse our anti-BRCA2 (BRCA2) Antibodies

Full name:
anti-Breast Cancer 2, Early Onset Antibodies (BRCA2)
On are 91 Breast Cancer 2, Early Onset (BRCA2) Antibodies from 24 different suppliers available. Additionally we are shipping BRCA2 Kits (24) and BRCA2 Proteins (2) and many more products for this protein. A total of 120 BRCA2 products are currently listed.
list all antibodies Gene Name GeneID UniProt
BRCA2 12190 P97929
BRCA2 675 P51587
BRCA2 360254  

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Most Popular Reactivities for anti-BRCA2 (BRCA2) Antibodies

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anti-Mouse (Murine) BRCA2 Antibodies:

anti-Human BRCA2 Antibodies:

anti-Rat (Rattus) BRCA2 Antibodies:

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Top referenced anti-BRCA2 Antibodies

  1. Human Monoclonal BRCA2 Primary Antibody for IHC, IHC (fro) - ABIN445493 : Bernard-Gallon, Déchelotte, Vissac, Aunoble, Cravello, Malpuech, Bignon: BRCA1 and BRCA2 protein expressions in an ovotestis of a 46, XX true hermaphrodite. in Breast cancer research : BCR 2001 (PubMed)
    Show all 2 references for ABIN445493

  2. Human Monoclonal BRCA2 Primary Antibody for IHC, IHC (p) - ABIN445491 : Wu, Jiang, Thangaraju, Wu, Couch: Induction of the BRCA2 promoter by nuclear factor-kappa B. in The Journal of biological chemistry 2000 (PubMed)
    Show all 2 references for ABIN445491

  3. Human Polyclonal BRCA2 Primary Antibody for IHC, ELISA - ABIN1533759 : Wooster, Bignell, Lancaster, Swift, Seal, Mangion, Collins, Gregory, Gumbs, Micklem: Identification of the breast cancer susceptibility gene BRCA2. in Nature 1996 (PubMed)
    Show all 2 references for ABIN1533759

  4. Human Polyclonal BRCA2 Primary Antibody for IHC, IHC (fro) - ABIN4285196 : Moeller, Yordy, Williams, Giri, Raju, Molkentine, Byers, Heymach, Story, Lee, Sturgis, Weber, Garden, Ang, Schwartz: DNA repair biomarker profiling of head and neck cancer: Ku80 expression predicts locoregional failure and death following radiotherapy. in Clinical cancer research : an official journal of the American Association for Cancer Research 2011 (PubMed)

More Antibodies against BRCA2 Interaction Partners

Zebrafish Breast Cancer 2, Early Onset (BRCA2) interaction partners

  1. Carcinogenesis in zebrafish with combined mutations in tp53 (show TP53 Antibodies) and brca2 typically requires biallelic mutation or loss of at least one of these genes.

  2. The novel role of Brca2 in organizing the vertebrate egg nucleus may provide new insights into the origin of ovarian cancer

  3. critical roles for brca2 in ovarian development and tumorigenesis in reproductive tissues

Mouse (Murine) Breast Cancer 2, Early Onset (BRCA2) interaction partners

  1. Merit40 (show BABAM1 Antibodies) mutation exacerbated ICL-induced chromosome instability in the context of concomitant Brca2 deficiency but not in conjunction with Fancd2 (show FANCD2 Antibodies) mutation.

  2. Heterozygous and homozygous Brca2 mutation may lead to dysfunction in T cell populations.

  3. BRCA2 exon 27 domain maintains chromosomal integrity at both stalled and collapsed replication forks consistent with involvement in both replication fork maintenance and double strand break repair.

  4. we use a genetically engineered mouse model of BRCA2-associated hereditary breast cancer to study drug resistance to several types of chemotherapy and PARP (show PARP1 Antibodies) inhibition.

  5. BRCA2-mediated sequestration of nuclear RAD51 (show RAD51 Antibodies) serves to prevent inappropriate DNA interactions.

  6. BRCA2 directly represses the expression of IFN-related genes

  7. the models reveal novel aspects of cancer evolution in carriers of germline BRCA2 mutations, provide new insights into the tumour suppressive role of BRCA2

  8. genetic stability, and hematopoietic differentiation potential of gene-corrected Brca2(Delta) (27/) (Delta) (27) iPSCs, achievements and limitations in the application of current reprogramming approaches in hematopoietic stem cell therapy are also discussed.

  9. Results suggest that cellular levels of Brca2 and Rad51 (show RAD51 Antibodies) are mutually dependent on each other, and that low levels of these proteins provide selective pressure for reduction of p53 (show TP53 Antibodies), which permits cell growth

  10. BRCA2 accumulates DNA damage, which triggers checkpoint signalling and ARF (show CDKN2A Antibodies) activation

Human Breast Cancer 2, Early Onset (BRCA2) interaction partners

  1. radiosensitization was at least partly due to the induction of apoptosis, which was only observed in the RKO cells and which may have been induced by BRCA2 degradation or different types of chromosomal aberrations.

  2. Association of BRCA2 single nucleotide polymorphisms with the breast cancer risk in the Bangladeshi population

  3. Rates of BRCA1 and BRCA2 mutation testing are increasing in young women with breast cancer. Given that knowledge and concern about genetic risk influence surgical decisions and may affect systemic therapy trial eligibility, all young women with breast cancer should be counseled and offered genetic testing, consistent with the National Comprehensive Cancer Network guidelines.

  4. The number of patients with uninformative BRCA genetic test(BRCA1 and BRCA2) results in this study is typical of reported high-risk screening populations. Next-generation sequencing has ushered in a new era of broad-spectrum testing for the growing list of potential genetic etiologies for breast cancer beyond BRCA

  5. that BRCA1/2 multicenter mutation testing is well feasible in formalin-fixed and paraffin-embedded tumor tissue

  6. BRCA2 mutation is associated with Breast Cancer.

  7. BRCA2 mutation is associated with breast and ovarian cancer.

  8. This is the first reported case of adrenocortical carcinoma associated with a BRCA2 germline mutation.

  9. BRCA2 Mutation is associated with Breast Cancer.

  10. No association between the thyroid hormones and breast cancer in BRCA1/2-mutation carriers was found

BRCA2 Antigen Profile

Antigen Summary

Inherited mutations in BRCA1 and this gene, BRCA2, confer increased lifetime risk of developing breast or ovarian cancer. Both BRCA1 and BRCA2 are involved in maintenance of genome stability, specifically the homologous recombination pathway for double-strand DNA repair. The BRCA2 protein contains several copies of a 70 aa motif called the BRC motif, and these motifs mediate binding to the RAD51 recombinase which functions in DNA repair. BRCA2 is considered a tumor suppressor gene, as tumors with BRCA2 mutations generally exhibit loss of heterozygosity (LOH) of the wild-type allele.

Alternative names and synonyms associated with BRCA2

  • breast cancer 2, early onset (BRCA2) antibody
  • breast cancer 2, early onset (brca2) antibody
  • breast cancer 2 (Brca2) antibody
  • breast cancer 2, early onset (Brca2) antibody
  • AI256696 antibody
  • AW045498 antibody
  • BRCA2 antibody
  • BRCC2 antibody
  • BROVCA2 antibody
  • FACD antibody
  • FAD antibody
  • FAD1 antibody
  • FANCB antibody
  • FANCD antibody
  • FANCD1 antibody
  • GLM3 antibody
  • PNCA2 antibody
  • RAB163 antibody

Protein level used designations for BRCA2

breast and ovarian cancer susceptibility protein 2 , breast cancer 2, early onset , breast cancer type 2 susceptibility protein-like , breast cancer type 2 susceptibility protein homolog , fanconi anemia group D1 protein homolog , BRCA1/BRCA2-containing complex, subunit 2 , breast and ovarian cancer susceptibility gene, early onset , breast cancer 2 tumor suppressor , breast cancer type 2 susceptibility protein , fanconi anemia group D1 protein , truncated breast and ovarian cancer susceptibility protein 2 , breast cancer 2, mutation 1, University of Wisconsin-Madison , breast cancer susceptibility protein 2

100064578 Equus caballus
566758 Danio rerio
584780 Strongylocentrotus purpuratus
721981 Macaca mulatta
100397509 Callithrix jacchus
452526 Pan troglodytes
100038818 Xenopus (Silurana) tropicalis
100601625 Nomascus leucogenys
12190 Mus musculus
675 Homo sapiens
360254 Rattus norvegicus
374139 Gallus gallus
474180 Canis lupus familiaris
507069 Bos taurus
493878 Felis catus
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