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Human Polyclonal Rad51B Primary Antibody for ELISA, WB - ABIN184859
Albala, Thelen, Prange, Fan, Christensen, Thompson, Lennon: Identification of a novel human RAD51 homolog, RAD51B. in Genomics 1998
Show all 2 references for ABIN184859
Human Polyclonal Rad51B Primary Antibody for WB - ABIN611112
Bossy, Petrilli, Klinglmayr, Chen, Lütz-Meindl, Knott, Masliah, Schwarzenbacher, Bossy-Wetzel: S-Nitrosylation of DRP1 does not affect enzymatic activity and is not specific to Alzheimer's disease. in Journal of Alzheimer's disease : JAD 2010
Notwithstanding their clearly established importance for RAD51 (show RAD51 Antibodies)-dependent homologous recombination, XRCC2, RAD51B and RAD51D (show RAD51D Antibodies) thus also participate in Single-Strand Annealing recombination.
The genome stability of the Arabidopsis thaliana mutants deficient in ATM (show ATM Antibodies) (communication between DNA strand break recognition and the repair machinery), KU80 (show XRCC5 Antibodies) (deficient in NHEJ) and RAD51B (deficient in HR repair) genes, was investigated.
The roles of RAD51B and XRCC2 in recombination are thus not limited to mitotic cells.
Results suggest that AtRAD51B gene product is involved in the repair of double-strand DNA breaks via homologous recombination. [Rad51B]
Our study shows that a miR (show MLXIP Antibodies)-590/Acvr2a (show ACVR2A Antibodies)/Rad51b signaling axis ensures the stabilization of mESCs by balancing DNA damage repair and rapid proliferation during self-renewal.
The aim of the present study was to evaluate the relationship between prostate cancer risk and the presence of single nucleotide polymorphisms in the genes involved in Homologous recombination repair, RAD51 (show RAD51 Antibodies), RAD51B, XRCC2 (show XRCC1 Antibodies) and XRCC3 (show XRCC3 Antibodies).
a novel germ line RAD51B nonsense mutation, and reduced expression of RAD51B in melanoma cells indicating inactivation of RAD51B
Mutations in epithelial ovarian cancer cases were more frequent in RAD51C (show RAD51C Antibodies) (14 occurrences, 0.41%) and RAD51D (show RAD51D Antibodies) (12 occurrences, 0.35%) than in RAD51B (two occurrences, 0.06%).
the risk of developing AMD (show AMD1 Antibodies) exhibits dose dependency as well as an epistatic combined effect in rs17105278 T>C and rs4902566 C>T carriers and that the elevated risk for rs17105278 T>C carriers may be due to decreased transcription of RAD51B.
Relative excess risk of breast cancer due to interaction between RAD51L1 single-nucleotide polymorphism and BMI.
Data indicate that complement factor H (CFH (show CFH Antibodies)) R1210C and common variants in COL8A1 (show COL8A1 Antibodies) and RAD51B plus six genes contribute predictive information for advanced macular degeneration (AMD (show AMD1 Antibodies)) beyond macular and behavioral phenotypes.
It confirms that RAD51 (show RAD51 Antibodies) paralog mutations confer breast and ovarian cancer predisposition and are rare events.
This study provides robust evidence for an association of rheumatoid arthritis susceptibility with genes involved in B cell differentiation (BACH2 (show BACH2 Antibodies)) and DNA repair (RAD51B).
The HsRAD51B-HsRAD51C complex plays a role in stabilizing the HsRAD51 (show RAD51 Antibodies) nucleoprotein filament during the presynaptic phase of homologous recombination.
Study observed centrosome defects in the absence of XRCC3 (show XRCC3 Antibodies). While RAD51B and RAD51C (show RAD51C Antibodies) act early in homologous recombination, XRCC3 (show XRCC3 Antibodies) functions jointly with GEN1 (show GEN1 Antibodies) later in the pathway at the stage of Holliday junction resolution.
The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are evolutionarily conserved proteins essential for DNA repair by homologous recombination. This protein has been shown to form a stable heterodimer with the family member RAD51C, which further interacts with the other family members, such as RAD51, XRCC2, and XRCC3. Overexpression of this gene was found to cause cell cycle G1 delay and cell apoptosis, which suggested a role of this protein in sensing DNA damage. At least three alternatively spliced transcript variants encoding distinct isoforms have been observed. Rearrangements between this locus and high mobility group AT-hook 2 (HMGA2, GeneID 8091) have been observed in uterine leiomyomata.
Rad51 DNA recombinase 2
, DNA repair protein RAD51 homolog 2
, RAD51-like 1
, RAD51-like protein 1
, RAD51 homolog B
, RecA-like protein
, recombination repair protein