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Browse our TP53BP1 (TP53BP1) ELISA Kits

Full name:
Tumor Protein P53 Binding Protein 1 ELISA Kits (TP53BP1)
On www.antibodies-online.com are 9 Tumor Protein P53 Binding Protein 1 (TP53BP1) ELISA Kits from 7 different suppliers available. Additionally we are shipping TP53BP1 Antibodies (156) and TP53BP1 Proteins (2) and many more products for this protein. A total of 169 TP53BP1 products are currently listed.
Synonyms:
53BP1, m53BP1, MGC160112, p202, Tp53bp1, Trp53bp1
list all ELISA KIts Gene Name GeneID UniProt
TP53BP1 27223 P70399
TP53BP1 7158 Q12888
TP53BP1 296099  

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TP53BP1 (TP53BP1) ELISA Kits by Reactivity

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Top referenced TP53BP1 ELISA Kits

  1. Human TP53BP1 ELISA Kit for Sandwich ELISA - ABIN825076 : Jacot, Thezenas, Senal, Viglianti, Laberenne, Lopez-Crapez, Bibeau, Bleuse, Romieu, Lamy: BRCA1 promoter hypermethylation, 53BP1 protein expression and PARP-1 activity as biomarkers of DNA repair deficit in breast cancer. in BMC cancer 2014 (PubMed)

More ELISA Kits for TP53BP1 Interaction Partners

Mouse (Murine) Tumor Protein P53 Binding Protein 1 (TP53BP1) interaction partners

  1. Study showed that mammalian cells use microtubules in the cytoplasm to promote the mobility of sites of DNA damage in the nucleus; molecular details of this process remain to be determined, the main players, including the MOB (show SGMS1 ELISA Kits) domain of 53BP1, the linker of the nucleoskeleton, and cytoskeleton complex, kinesins, and microtubules are now known, allowing further study.

  2. These experiments define a novel requirement for 53BP1 in the fusions of DNA-PKcs (show PRKDC ELISA Kits)-deficient telomeres throughout the cell cycle.

  3. Study concludes that only the 53BP1 status in DNA lesions, induced by UVA or gamma-rays, is affected by A-type lamin (show LMNA ELISA Kits) deficiency, which was not observed for heterochromatin-related proteins HP1beta (show CBX1 ELISA Kits) and BMI1 (show BMI1 ELISA Kits).

  4. Binding of 53BP1 to methyl K810 occurs on E2 promoter binding factor (show E2F1 ELISA Kits) target genes and allows pRb (show PGR ELISA Kits) activity to be effectively integrated with the DNA damage response.

  5. study uncovers novel ATM (show ATM ELISA Kits)-independent functions for 53BP1 in the suppression of oncogenic translocations and in radioprotection

  6. Study concludes that 53BP1 promotes productive class switch recombination and suppresses mutagenic DNA repair through distinct phosphodependent interactions with RIF1 (show RIF1 ELISA Kits) and PTIP (show PAXIP1 ELISA Kits).

  7. Thus, RIF1 and 53BP1 cooperate to block DSB resection to promote NHEJ in G1, which is antagonized by BRCA1 in S phase to ensure a switch of DSB repair mode to homologous recombination

  8. loss of 53BP1 alters the translocatome by increasing rearrangements to intergenic regions.

  9. A mutant lacking the oligomerization domain (53BP1(oligo)) was only modestly impaired in promoting NHEJ of dysfunctional telomeres and showed no defect with regard to the repression of CtIP (show RBBP8 ELISA Kits).

  10. data establish Rif1 (show RIF1 ELISA Kits) as an important contributor to the control of double-strand break repair by 53BP1

Human Tumor Protein P53 Binding Protein 1 (TP53BP1) interaction partners

  1. we show that XIST and 53BP1 can be used to identify BRCA1-like breast cancer patients that have higher event rates and poor outcome after HD chemotherapy.

  2. kinetics of the accumulation of selected DNA repair-related proteins is protein specific at locally induced DNA lesions, and that the formation of gH2AX- and NBS1-positive foci, but not 53BP1-positive NBs, is cell cycle dependent in HeLa cells

  3. the interaction of 53BP1 with gammaH2AX (show H2AFX ELISA Kits) is required for sustaining the 53BP1-dependent focal concentration of activated ATM (show ATM ELISA Kits) that facilitates repair of DNA double-strand breaks in heterochromatin in G1.

  4. cryo-EM structure of a dimerized human 53BP1 fragment bound to a H4K20me2-containing and H2AK15ub-containing nucleosome core particle at 4.5 A resolution

  5. The study shows higher expression of gamma-H2AX (show H2AFX ELISA Kits) and 53BP1 foci in rectal cancer patients compared with healthy individuals. Yet the data in vitro were not predictive in regard to the radiotherapy outcome.

  6. For both, gamma-H2AX (show H2AFX ELISA Kits) and 53BP1, the cellular focus number as well as the percentage of positive cells did not differ between patients with clinically isolated syndrome/early relapsing-remitting multiple sclerosis and healthy controls.

  7. Impaired TIP60 (show KAT5 ELISA Kits)-mediated H4K16 acetylation accounts for the aberrant chromatin accumulation of 53BP1 and RAP80 (show UIMC1 ELISA Kits) in Fanconi anemia (show PALB2 ELISA Kits) pathway-deficient cells.

  8. Depleting 53BP1, which slows cNHEJ, fully rescues the nuclear and cytogenetic abnormalities seen with EEPD1 depletion

  9. Suggest 53BP1 may serve as a candidate biomarker for predicting prognosis and disease development in colorectal cancer.

  10. After nanogold treatment, an inverse correlation between the formation of 53BP1 foci and micronuclei generation was observed. The robust 53BP1 recruitment resulted in reduced micronuclei production

TP53BP1 Antigen Profile

Antigen Summary

May have a role in checkpoint signaling during mitosis. Enhances TP53-mediated transcriptional activation. Binds to sites of DNA damage. Plays a role in the response to DNA damage (By similarity).

Alternative names and synonyms associated with TP53BP1

  • tumor protein p53 binding protein 1 (TP53BP1) Elisa Kit
  • tumor protein p53 binding protein 1 (tp53bp1) Elisa Kit
  • tumor protein p53 binding protein 1 (predicted), 5 prime (TP53BP1) Elisa Kit
  • transformation related protein 53 binding protein 1 (Trp53bp1) Elisa Kit
  • tumor protein p53 binding protein 1 (Tp53bp1) Elisa Kit
  • 53BP1 Elisa Kit
  • m53BP1 Elisa Kit
  • MGC160112 Elisa Kit
  • p202 Elisa Kit
  • Tp53bp1 Elisa Kit
  • Trp53bp1 Elisa Kit

Protein level used designations for TP53BP1

tumor protein p53 binding protein 1 , tumor protein p53 binding protein, 1 , tumor suppressor p53-binding protein 1-like , tumor protein p53 binding protein 1 (predicted), 5 prime , tumor protein p53 binding protein 1 (predicted), 3 prime , murine p53-binding protein , p53-binding protein 1 , p53BP1 , transformation related protein 53 binding-protein 1 , tumor suppressor p53-binding protein 1 , tumor protein 53-binding protein, 1 , tumor protein p53-binding protein, 1 , transformation related protein 53 binding protein 1

GENE ID SPECIES
415589 Gallus gallus
467668 Pan troglodytes
478274 Canis lupus familiaris
509111 Bos taurus
100137429 Papio anubis
100468474 Ailuropoda melanoleuca
100490124 Xenopus (Silurana) tropicalis
100550605 Meleagris gallopavo
100607698 Nomascus leucogenys
100328680 Oryctolagus cuniculus
27223 Mus musculus
7158 Homo sapiens
296099 Rattus norvegicus
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