Browse our anti-XRCC4 (XRCC4) Antibodies

Full name:
anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 4 Antibodies (XRCC4)
On are 108 X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 4 (XRCC4) Antibodies from 22 different suppliers available. Additionally we are shipping XRCC4 Proteins (6) and XRCC4 Kits (3) and many more products for this protein. A total of 126 XRCC4 products are currently listed.
2310057B22Rik, AW413319, AW545101, homolog of human DNA ligase iv-binding protein XRCC4, MGC81443, zgc:73312
list all antibodies Gene Name GeneID UniProt
XRCC4 7518 Q13426
XRCC4 108138 Q924T3
XRCC4 309995  

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anti-Rat (Rattus) XRCC4 Antibodies:

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Top referenced anti-XRCC4 Antibodies

  1. Human Monoclonal XRCC4 Primary Antibody for IF, WB - ABIN968566 : Gao, Sun, Frank, Dikkes, Fujiwara, Seidl, Sekiguchi, Rathbun, Swat, Wang, Bronson, Malynn, Bryans, Zhu, Chaudhuri, Davidson, Ferrini, Stamato, Orkin, Greenberg, Alt: A critical role for DNA end-joining proteins in both lymphogenesis and neurogenesis. in Cell 1999 (PubMed)
    Show all 3 references for 968566

  2. Human Polyclonal XRCC4 Primary Antibody for ICC, IF - ABIN4366467 : Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. in Nature methods 2013 (PubMed)
    Show all 2 references for 4366467

  3. Cow (Bovine) Polyclonal XRCC4 Primary Antibody for WB - ABIN2778273 : Yen, Liu, Chen, Tseng, Chuang, Yang, Lin, Wen, Chiang, Ho, Chen, Wang, Lin, Chang: Combinational polymorphisms of four DNA repair genes XRCC1, XRCC2, XRCC3, and XRCC4 and their association with oral cancer in Taiwan. in Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2008 (PubMed)

  4. Human Polyclonal XRCC4 Primary Antibody for IF, IHC (p) - ABIN1327721 : Enervald, Du, Visnes, Björkman, Lindgren, Wincent, Borck, Colleaux, Cormier-Daire, van Gent, Pie, Puisac, de Miranda, Kracker, Hammarström, de Villartay, Durandy, Schoumans, Ström, Pan-Hammarström: A regulatory role for the cohesin loader NIPBL in nonhomologous end joining during immunoglobulin class switch recombination. in The Journal of experimental medicine 2013 (PubMed)

  5. Mouse (Murine) Polyclonal XRCC4 Primary Antibody for IHC, WB - ABIN3022382 : Dong, Wang, Wang, Zhang, Zhu, Gao, Yang, Qin, Liang, Chen, Deng, Ning, Liang, Gao, Xu: A stress-induced cellular aging model with postnatal neural stem cells. in Cell death & disease 2014 (PubMed)

  6. Human Polyclonal XRCC4 Primary Antibody for ICC, IF - ABIN440923 : van Sluis, McStay: A localized nucleolar DNA damage response facilitates recruitment of the homology-directed repair machinery independent of cell cycle stage. in Genes & development 2015 (PubMed)

More Antibodies against XRCC4 Interaction Partners

Arabidopsis thaliana X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 4 (XRCC4) interaction partners

  1. XRCC4 has a negative role in Agrobacterium T-DNA integration.

Human X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 4 (XRCC4) interaction partners

  1. the various XRCC4 mutations that lead to primordial dwarfism and their impact on non-homologous end joining and V(D)J recombination are discussed (Review)

  2. XRCC4 expression might have an influence on results of radiotherapy for patients with esophageal squamous cell carcinoma.

  3. uterine cervical cancer patients with high Ku86 (show XRCC5 Antibodies) and XRCC4 expression had a significantly lower 5-year metastasis-free rate than others.

  4. Frequencies of XRCC4-1394 T/G+G/G genotypes were higher in patients (%34) than the controls (%18.7). The statistical analysis revealed that the individuals who had XRCC4-1394 T/G+G/G genotype had an increased risk for autism spectrum disorder (OR = 2.23, 95% CI = 1.10-4.55)

  5. Genetic Variations in XRCC4 (rs1805377) is not Associated with Hepatocellular Carcinoma in Thai Patients with Hepatitis B Virus Infection.

  6. These results suggested potential usefulness of the phosphorylation status of XRCC4 Ser320 as an indicator of DNA-PK functionality in living cells.

  7. Association between insertion/deletion polymorphism in intron 3 of XRCC4 and susceptibility to type I bipolar disorder

  8. For XRCC4 (rs1805377) polymorphism, no difference was found in distribution between the ESCC and control groups.

  9. using dual- and quadruple-trap optical tweezers combined with fluorescence microscopy, we show how human XRCC4, XLF (show NHEJ1 Antibodies) and XRCC4-XLF (show NHEJ1 Antibodies) complexes interact with DNA in real time

  10. The ends are then closely aligned, which requires XLF (show NHEJ1 Antibodies), a non-catalytic function of XRCC4-LIG4 (show LIG4 Antibodies), and DNA-PK activity

Mouse (Murine) X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 4 (XRCC4) interaction partners

  1. We find that non-canonical HR termination can occur in the absence of the classical non-homologous end joining gene XRCC4. We observe obligatory use of microhomology (MH)-mediated end joining and/or nucleotide addition during rejoining with the second end of the break

  2. Data show that combined deletion of X-ray repair cross-complementing protein 4 (Xrcc4) and tumor suppressor p53 (Trp53 (show TP53 Antibodies)) predisposes B cells to lymphomagenesis.

  3. FBXW7 (show FBXW7 Antibodies) facilitates nonhomologous end-joining via K63-linked polyubiquitylation of XRCC4 in tumor cells.

  4. The present results collectively indicated that Lys271, but not Lys210, of XRCC4 is required for the nuclear localization of XRCC4 and LIG4 (show LIG4 Antibodies) and that the nuclear localizing ability is essential for DSB repair function of XRCC4.

  5. DNA-PK and ATM (show ATM Antibodies) acts in parallel upstream of XRCC4, regulating through phosphorylation

  6. XRCC4 C-terminal point mutants, R325F and N326L, are functionally deficient in terms of cell survival after irradiation.

  7. These results establish that nonrecurrent CNVs can be, and frequently are, formed by mechanisms other than Xrcc4-dependent NHEJ.

  8. analysis of the association of radiation-induced XRCC4 with chromatin DNA, by biochemical fractionation

  9. conditional inactivation of the XRCC4 in nestin (show NES Antibodies)-expressing neuronal progenitor cells, although leading to no obvious phenotype in a WT background, leads to early onset of neuronally differentiated medulloblastomas (MBs (show NEU2 Antibodies)) in a p53 (show TP53 Antibodies)-deficient background

  10. DNA-PK kinase activity results in disassembly of the Ku/DNA ligase IV (show LIG4 Antibodies)/Xrcc4 complex

XRCC4 Antigen Profile

Antigen Summary

The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. The non-homologous end-joining pathway is required both for normal development and for suppression of tumors. This gene functionally complements XR-1 Chinese hamster ovary cell mutant, which is impaired in DNA double-strand breaks produced by ionizing radiation and restriction enzymes. Alternative transcription initiation and alternative splicing generates several transcript variants.

Alternative names and synonyms associated with XRCC4

  • X-ray repair complementing defective repair in Chinese hamster cells 4 (XRCC4) antibody
  • X-ray repair complementing defective repair in Chinese hamster cells 4 (xrcc4) antibody
  • DNA repair protein XRCC4-like protein (XRCC4) antibody
  • X-ray repair complementing defective repair in Chinese hamster cells 4 (Xrcc4) antibody
  • 2310057B22Rik antibody
  • AW413319 antibody
  • AW545101 antibody
  • homolog of human DNA ligase iv-binding protein XRCC4 antibody
  • MGC81443 antibody
  • zgc:73312 antibody

Protein level used designations for XRCC4

DNA repair protein XRCC4 , X-ray repair complementing defective repair in Chinese hamster cells 4 , DNA-repair protein XRCC4 , X-ray repair cross complementing protein 4 , X-ray repair cross-complementing protein 4 , X-ray repair, complementing defective, repair in Chinese hamster

488923 Canis lupus familiaris
393759 Danio rerio
427325 Gallus gallus
443786 Xenopus laevis
471491 Pan troglodytes
100127743 Xenopus (Silurana) tropicalis
100173078 Pongo abelii
100603402 Nomascus leucogenys
821885 Arabidopsis thaliana
7518 Homo sapiens
613590 Bos taurus
108138 Mus musculus
309995 Rattus norvegicus
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