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High ALDH1A1 expression is associated with cervical cancer.
Study shows that BPA (show DST ELISA Kits) induces ALDH1 expression in MCF-7 Cells and increases mammosphere size.
High ALDH expression is associated with Prostate Cancer.
High ALDH1 expression is associated with endometrial cancer.
A central role of Aurora kinase A (AURKA (show AURKA ELISA Kits)) in promoting Epithelial-to-mesenchymal transition and cancer stem cell phenotypes via ALDH1A1.
ALDH1A1 modulates the production of ROS (show ROS1 ELISA Kits) by anti-cancer agents such as paclitaxel and diminishes their efficacy.
High expression of ALDH1 is associated with non-small cell lung cancer.
NOR1 (show NR4A3 ELISA Kits) suppresses cancer stem-like cell properties in nasopharyngeal carcinoma cells by inhibiting the AKT (show AKT1 ELISA Kits)-GSK-3beta (show GSK3b ELISA Kits)-Wnt (show WNT2 ELISA Kits)/beta-catenin (show CTNNB1 ELISA Kits)-ALDH1A1 signaling circuit.
FBLN-3 (show FBLN3 ELISA Kits) promoter region was highly methylated in some pancreatic cancer cell lines. FBLN-3 (show FBLN3 ELISA Kits) inhibited c-MET activation and expression and reduced cellular level of ALDH1.
ALDH1A1 silencing induced sensitivity in the cisplatin resistant head and neck cancer cell line In Vitro.
analysis of bioactivation of nitroglycerin by purified mitochondrial and cytosolic aldehyde dehydrogenases ALDH1 and ALDH2 (show ALDH2 ELISA Kits)
Data indicate involvement of non-POU domain-containing octamer-binding protein (NONO (show NONO ELISA Kits))/paraspeckle protein component 1 (PSPC1 (show PSPC1 ELISA Kits))-aldehyde dehydrogenase 1 (NONO (show NONO ELISA Kits)/PSPC1 (show PSPC1 ELISA Kits)-ALDH1A1) in the modulation of Sertoli cells (SCs (show TWIST1 ELISA Kits)) response to mono-(2-ethylhexyl) phthalate (MEHP) challenge.
In ovaries lacking ALDH1A1, the onset of germ cell meiosis is delayed.
Dioxin receptor regulates aldehyde dehydrogenase to block melanoma tumorigenesis and metastasis
these experiments reveal an evolutionarily conserved GABA synthesis pathway mediated by aldehyde dehydrogenase 1a1 (ALDH1a1).
Respiratory tract epithelial cells express retinaldehyde dehydrogenase ALDH1A and enhance IgA production by stimulated B cells in the presence of vitamin A.
Dkk-1 (show DKK1 ELISA Kits) enhances resistance of osteosarcoma cells to stress by tipping balance of Wnt (show WNT2 ELISA Kits) signaling in favor of the non-canonical Jun (show JUN ELISA Kits)-mediated Wnt (show WNT2 ELISA Kits) pathways. In turn, this results in transcriptional activation of ALDH1 through Jun (show JUN ELISA Kits)-responsive promoter elements.
Deletion of Aldh1a1 exacerbated alpha-synuclein (show SNCA ELISA Kits)-mediated DA neurodegeneration and alpha-synuclein (show SNCA ELISA Kits) aggregation, whereas Aldh1a1-null and control DA neurons were comparably susceptible to 1-methyl-4-phenylpyridinium-, glutamate (show GRIN1 ELISA Kits)-, or camptothecin-induced cell death.
Our findings indicated that increased expression of ALDH1A1 in nasopharyngeal carcinoma was associated with enhanced invasiveness in the nude mouse.
PSMB8 (show PSMB8 ELISA Kits), ALDH1A1, and HSPA4 (show HSPA4 ELISA Kits) were identified to be located in ovarian tissues, to regulate 12 cellular pathways, and demonstrate age-dependent dynamic changes in expression profiling.
beta-escin inhibits tobacco carcinogen-induced lung tumor formation by modulating ALDH1A1-positive cells and RhoA (show RHOA ELISA Kits)/Rock signaling
The protein encoded by this gene belongs to the aldehyde dehydrogenase family. Aldehyde dehydrogenase is the next enzyme after alcohol dehydrogenase in the major pathway of alcohol metabolism. There are two major aldehyde dehydrogenase isozymes in the liver, cytosolic and mitochondrial, which are encoded by distinct genes, and can be distinguished by their electrophoretic mobility, kinetic properties, and subcellular localization. This gene encodes the cytosolic isozyme. Studies in mice show that through its role in retinol metabolism, this gene may also be involved in the regulation of the metabolic responses to high-fat diet.
aldehyde dehydrogenase 1A1
, retinal dehydrogenase 1
, aldehyde dehydrogenase 1 family, member A1
, aldehyde dehydrogenase class 1
, retinal dehydrogenase 1-like
, aldehyde dehydrogenase
, aldehyde dehydrogenase family protein
, NADP-dependent fatty aldehyde dehydrogenase
, ALDH class 1
, RALDH 1
, acetaldehyde dehydrogenase 1
, aldehyde dehydrogenase 1, soluble
, aldehyde dehydrogenase, liver cytosolic
, retinaldehyde dehydrogenase 1
, chromosome 1 GSS clone AHT1-34
, aldehyde dehydrogenase 1, subfamily A1
, aldehyde dehydrogenase 2
, aldehyde dehydrogenase family 1 member A1
, aldehyde dehydrogenase family 1, member A1
, aldehyde dehydrogenase family 1, subfamily A1
, aldehyde dehydrogenase, cytosolic
, cytosolic aldehyde dehydrogenase
, ALDH class 2
, aldehyde dehydrogenase 2, mitochondrial
, aldehyde dehydrogenase, mitochondrial
, mitochondrial aldehyde dehydrogenase
, alcohol dehydrogenase family 1, subfamily A1
, alcohol dehydrogenase family 1, subfamily A2
, aldehyde dehydrogenase 1, liver cytosolic (class 1)