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Browse our Engrailed Homeobox 1 Proteins (EN1)

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Engrailed Homeobox 1 Proteins (EN1)
On are 3 Engrailed Homeobox 1 (EN1) Proteins from 2 different suppliers available. Additionally we are shipping Engrailed Homeobox 1 Antibodies (27) and many more products for this protein. A total of 34 Engrailed Homeobox 1 products are currently listed.
en-1, en-3, en1, en1-A, ENG-1, eng1, engrailed-1, Gg-En-1, Mo-en.1, xen1, zgc:100771
list all proteins Gene Name GeneID UniProt
EN1 13798 P09065
EN1 2019 Q05925
Rat EN1 EN1 685360  

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Engrailed Homeobox 1 Proteins (EN1) by Origin

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More Proteins for Engrailed Homeobox 1 Interaction Partners

Mouse (Murine) Engrailed Homeobox 1 (EN1) interaction partners

  1. En1-null cells also fail to express the transcription factor FoxP1 (show FOXP1 Proteins), suggesting that FoxP1 (show FOXP1 Proteins) lies downstream of En1.

  2. The homeoprotein Engrailed is not only a survival factor for mesencephalic dopaminergic (mDA) neurons during development, but continues to exert neuroprotective and physiological functions in adult mDA neurons. [Review]

  3. En1+/Otx2 (show OTX2 Proteins) Mutants Exhibit Increased Intra-Individual Fluctuation in Activity, Habituation, Risk-Taking Behavior, Sociability, and Hedonic-Like Behavior.

  4. En1 is involved in two distinct molecular mechanisms that regulate the establishment of neuronal connectivity to limb-musculature.

  5. low-frequency non-coding variant near a novel locus, EN1, with an effect on bone mineral density--which was also associated with a decreased risk of fracture

  6. The findings of this study support a progressive retrograde degeneration of En1(+/-) nigrostriatal neurons, akin to what is suggested to occur in Parkinson disease.

  7. This study identified En1 as a gene essential for MNTB neuron development and Sound localization.

  8. Two crucial mediators of mesodiencephalic dopaminergic neuronal development, En1 and Pitx3 (show PITX3 Proteins), interact in dopaminergic subset specification.

  9. Analysis of an allelic series of conditional mutants showed that En1 is the predominant functional En paralog in maturing 5-HT (show DDC Proteins) neurons

  10. En1 and En2 (show EN2 Proteins) act together in multiple cerebellar cell types to determine overall growth and formation of particular fissures.

Human Engrailed Homeobox 1 (EN1) interaction partners

  1. low-frequency non-coding variant near a novel locus, EN1, with an effect on bone mineral density--which was also associated with a decreased risk of fracture

  2. EN1 is an activator of intrinsic inflammatory pathways associated with prosurvival in basal-like breast cancer.

  3. The current review describes the role of two such factors, Nurr1 and engrailed, in differentiation, maturation, and in normal physiological functions including acquisition of neurotransmitter identity.

  4. EN1 is a biologic predictor of poor prognosis in patients with salivary adenoid cystic carcinoma.

  5. Homeobox protein engrailed-1 protein regulates transcription of the utrophin gene.

  6. EN1 might be a negative regulatory factor for UTROPHIN.

  7. The result of this study found a strong association between the EN1 rs1438852 polymorphism and Parkinson's disease.

  8. En-1 exerts its repressive effect by a mechanism negatively controlling the level of beta-catenin (show CTNNB1 Proteins).

  9. When beta-catenin (show CTNNB1 Proteins) is activated in transgenic En1 expressing cells, it induces Dermo1 (show TWIST2 Proteins) expression in all cells of the En1 domain and disrupts muscle gene expression.

  10. Epigenetic suppression along 2q14.2 is common to most colorectal cancers and the presence of a methylated EN1 CpG island in stool DNA might be used as biomarker of neoplastic disease.

Engrailed Homeobox 1 (EN1) Protein Profile

Protein Summary

Homeobox-containing genes are thought to have a role in controlling development. In Drosophila, the 'engrailed' (en) gene plays an important role during development in segmentation, where it is required for the formation of posterior compartments. Different mutations in the mouse homologs, En1 and En2, produced different developmental defects that frequently are lethal. The human engrailed homologs 1 and 2 encode homeodomain-containing proteins and have been implicated in the control of pattern formation during development of the central nervous system.

Alternative names and synonyms associated with Engrailed Homeobox 1 (EN1)

  • engrailed (EN1)
  • engrailed homolog 1 (LOC100014221)
  • engrailed 1 (En1)
  • engrailed 1a (eng1a)
  • engrailed homeobox 1 (en1-b)
  • engrailed homeobox 1 (EN1)
  • engrailed homeobox 1 (En1)
  • en-1 protein
  • en-3 protein
  • en1 protein
  • en1-A protein
  • ENG-1 protein
  • eng1 protein
  • engrailed-1 protein
  • Gg-En-1 protein
  • Mo-en.1 protein
  • xen1 protein
  • zgc:100771 protein

Protein level used designations for Engrailed Homeobox 1 Proteins (EN1)

engrailed , engrailed homolog 1 , engrailed-1 , homeobox protein en-1 , homeobox protein engrailed-1 , mo-En-1 , homeobox protein en-1a , homeobox protein engrailed-1a , engrailed 1 , Engrailed-3 , hu-En-1

280782 Bos taurus
100014221 Monodelphis domestica
13798 Mus musculus
30244 Danio rerio
378659 Xenopus laevis
771008 Gallus gallus
2019 Homo sapiens
685360 Rattus norvegicus
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