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Browse our NEUROD1 Proteins (NEUROD1)

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Neuronal Differentiation 1 Proteins (NEUROD1)
On are 9 Neuronal Differentiation 1 (NEUROD1) Proteins from 4 different suppliers available. Additionally we are shipping NEUROD1 Antibodies (116) and NEUROD1 Kits (4) and many more products for this protein. A total of 134 NEUROD1 products are currently listed.
Beta2, BHF-1, bHLHa3, MGC82572, MODY6, neuro-D, neuroD, neurod1, nrd, XNeuroD
list all proteins Gene Name GeneID UniProt
NEUROD1 18012 Q60867
NEUROD1 4760 Q13562
Rat NEUROD1 NEUROD1 29458 Q64289

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NEUROD1 Proteins (NEUROD1) by Origin

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More Proteins for NEUROD1 Interaction Partners

Zebrafish Neuronal Differentiation 1 (NEUROD1) interaction partners

  1. during embryonic development, NeuroD governs photoreceptor genesis via non-cell-autonomous mechanisms and that, during photoreceptor development and regeneration, Notch signaling is a mechanistic link between NeuroD and cell cycle exit.

  2. differential levels of Neurod are required to generate endocrine pancreas subtypes from precursors during both embryonic and larval stages

  3. Transcription factor neuroD, involved in retinogenesis, is co-opted by the circadian clock following photoreceptor differentiation.

  4. Nkx2.2 coordinately activates NeuroD1 with Ngn3 in the endocrine progenitor cell and plays a role in the maintenance of NeuroD1 expression to regulate beta cell function in the mature islet.

  5. The control of endocrine cell fate is instead fulfilled by two basic helix-loop-helix factors, Ascl1b and Neurod1 and NEUROG3 (show NEUROG3 Proteins) is not the unique pancreatic endocrine cell fate determinant in vertebrates.

  6. the quantity, rather than quality (i.e., the ON/OFF states), of neurod expression directly or indirectly determines the two subtypes of posterior lateral line neurons

  7. BrdU-, neuroD (nrd)- and Hu-studies reveal unusual non-ventricular neurogenesis in the postembryonic zebrafish forebrain.

  8. in the zebrafish, two proneural genes are essential for differentiation of the hair cells, neuroD and atonal homolog 1

  9. Coexpressed with cone-rod-homeobox (show CRX Proteins) transcription factor (Crx (show CRX Proteins)) in putative cone progenitors and nascent cone photoreceptors. In zebrafish retina, similar genetic cascades may regulate photoreceptor genesis and maturation.

  10. NeuroD plays a fundamental role in photoreceptor genesis by regulating mechanisms that promote rod and cone progenitors to withdraw from the cell cycle.

Mouse (Murine) Neuronal Differentiation 1 (NEUROD1) interaction partners

  1. Wnt3a increased the expression of NeuroD1 and Ins2 in the hypothalamus.

  2. The authors show that NeuroD1 directly binds regulatory elements of neuronal genes that are developmentally silenced by epigenetic mechanisms.

  3. Expression of Transcription Factor NeuroD1 in Olfactory Bulb Glutamatergic Neurons

  4. Data show that RNA binding protein HuD and special adenine-thymine (AT)-rich DNA-binding protein 1 (SATB1) form a positive regulatory loop that enhances NeuroD1 protein transcription and subsequent neuronal differentiation.

  5. Neurod1 regulates the developments of opioid tolerance via a time-dependent pathway through contextual learning and a short-response pathway through antinociception.

  6. The authors report the generation and characterization of Neurod1-CreER(T2) mouse lines and show that Neurod1 is not only expressed in immature newborn neurons of the adult hippocampus but also in fully mature granule cells of the dentate gyrus.

  7. Study demonstrates a sequential expression order of NEUROD1>ISL1 (show ISL1 Proteins)>POU4F1 (show POU4F1 Proteins)>POU4F2 (show POU4F2 Proteins) during the inner ear neurogenesis.

  8. In this study, we tried to establish an effective method of differentiation through the protein transduction of three transcription factors (Pdx1 (show PDX1 Proteins), NeuroD, and MafA (show MAFA Proteins)) important to pancreatic beta cell development.

  9. These data suggest that melatonin, by acting on MT1 receptors, affects NeuroD expression in the gastrointestinal tract and thus might contribute to circadian regulation in metabolic functions.

  10. NeuroD-dependent neuronal death occurs through a Bax (show BAX Proteins)-dependent apoptotic pathway

Cow (Bovine) Neuronal Differentiation 1 (NEUROD1) interaction partners

  1. The objective of this study was to identify polymorphisms in the functional and positional candidate gene NEUROD1 (neurogenic differentiation 1), and investigate their associations with production traits in reference families of Nelore cattle, seven single nucleotide polymorphisms (SNPs) in NEUROD1 were identified. Investigated marker effects on traits RFI, backfat thickness, ribeye area, body weight, metabolics

Xenopus laevis Neuronal Differentiation 1 (NEUROD1) interaction partners

  1. Premature misexpression of NeuroD1 in chick partially recapitulates the amphibian condition by suppressing transit amplification.

  2. NeuroD1 gene activity is turned on in new born neurons during post-metamorphic neurogenesis.

  3. NeuroD promoter is substantially more sensitive to the phosphorylation status of Ngn2 (show NEUROG2 Proteins) than the Delta promoter, and that this can be attributed to differences in the ease of promoter activation.

  4. This study reveals that the early larval stage in Xenopus (Stage 48) displays patterns of proliferation (NeuroD).

  5. Data demonstrate that Neurogenin and NeuroD preferentially recognize neurogenesis-related targets through an enhancer signature of clustered consensus-binding sites and regulate neurogenesis by activating a core set of transcription factors.

Human Neuronal Differentiation 1 (NEUROD1) interaction partners

  1. NeuroD1 seemed not sufficient to induce and maintain neuronal differentiation. Induction of neuronal differentiation by overexpression of Neurog1 (show NEUROG1 Proteins) initiated important steps for the development of glutamatergic neurons such as the spiral ganglion neurons

  2. Study reports a family with autosomal dominant diabetes related to a new NEUROD1 mutation, one of very few meeting Maturity Onset Diabetes of the Young criteria.

  3. RNAi of lentiviral vector target NeuroD can reduce the migration and invasion abilities of PANC-1 cells

  4. this study concludes that the novel mechanism would regulate the expression of ALK in neuroblastoma (show ARHGEF16 Proteins) and that NeuroD1 should be significantly involved in neuroblastoma (show ARHGEF16 Proteins) tumorigenesis.

  5. NEUROD1 is important for maintenance of the retina function and partial loss-of-function mutation in NEUROD1 is likely a rare cause of nonsyndromic ARRP.

  6. Increased expression of NeuroD1 subsequently leads to regulation of expression and function of the nicotinic acetylcholine receptor subunit cluster of alpha3, alpha5, and beta4.

  7. Transactivation of Ctbp (show CTBP2 Proteins) was dependent on the histone H3 (show HIST3H3 Proteins) lysine 9 (H3K9) demethylase activity of LSD1 (show KDM1A Proteins) facilitates subsequent H3K9 acetylation by the NeuroD1-associated histone acetyltransferase, P300/CBP-associated factor (show KAT2B Proteins).

  8. Gene expression profiling revealed that permissive lines are typified by lower expression of the early neurogenic transcription factor ASCL1 and, conversely, by higher expression of the late neurogenic transcription factor NEUROD1.

  9. NeuroD1 regulates survival and migration of neuroendocrine lung carcinomas via signaling molecules TrkB (show NTRK2 Proteins) and NCAM (show NCAM1 Proteins).

  10. The overexpression of NeuroD may contribute to the tumorogenesis and development of pancreatic carcinoma, and is closely correlated to the cancer cell proliferation, p53 (show TP53 Proteins) signal pathway and neural invasion.

Pig (Porcine) Neuronal Differentiation 1 (NEUROD1) interaction partners

  1. Report pancreatic expression of NeuroD1 in pancreas.

  2. NeuroD might be an essential regulatory factor for transcription of pig AgRP (show AGRP Proteins), playing a role in energy homeostasis regulation in the porcine and human brain.

NEUROD1 Protein Profile

Protein Summary

This gene encodes a member of the NeuroD family of basic helix-loop-helix (bHLH) transcription factors. The protein forms heterodimers with other bHLH proteins and activates transcription of genes that contain a specific DNA sequence known as the E-box. It regulates expression of the insulin gene, and mutations in this gene result in type II diabetes mellitus.

Alternative names and synonyms associated with NEUROD1

  • neurogenic differentiation (neurod)
  • neurogenic differentiation 1 (NEUROD1)
  • neurogenic differentiation 1 (Neurod1)
  • neuronal differentiation 1 (neurod1-b)
  • neuronal differentiation 1 (NEUROD1)
  • neuronal differentiation 1 (Neurod1)
  • neuronal differentiation 1 (neurod1-a)
  • Beta2 protein
  • BHF-1 protein
  • bHLHa3 protein
  • MGC82572 protein
  • MODY6 protein
  • neuro-D protein
  • neuroD protein
  • neurod1 protein
  • nrd protein
  • XNeuroD protein

Protein level used designations for NEUROD1

Beta2/NeuroD , NDF1 , etID309883.9 , neuroD1 , neurogenic differentiation factor 1 , beta-cell E-box transcriptional activator 2 , neurogenic differentiation 1 , basic helix-loop-helix transcription factor , beta-cell E-box transactivator 2 , class A basic helix-loop-helix protein 3 , neurogenic helix-loop-helix protein NEUROD , BHF-1 , basic helix-loop-helix factor 1 , NeuroD/Beta2 , Beta-cell E-box transcriptional activator 2 , Neurogenic differentiation factor 1

30169 Danio rerio
395754 Gallus gallus
18012 Mus musculus
539487 Bos taurus
444022 Xenopus laevis
4760 Homo sapiens
29458 Rattus norvegicus
488431 Canis lupus familiaris
397283 Sus scrofa
101829221 Mesocricetus auratus
378541 Xenopus laevis
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