You are viewing an incomplete version of our website. Please click to reload the website as full version.

Browse our ADAM12 Proteins (ADAM12)

Full name:
ADAM Metallopeptidase Domain 12 Proteins (ADAM12)
On are 16 ADAM Metallopeptidase Domain 12 (ADAM12) Proteins from 7 different suppliers available. Additionally we are shipping ADAM12 Antibodies (82) and ADAM12 Kits (26) and many more products for this protein. A total of 136 ADAM12 products are currently listed.
adam12, MCMP, MCMPMltna, mKIAA4001, MLTN, MLTNA
list all proteins Gene Name GeneID UniProt
ADAM12 11489 Q61824
ADAM12 8038 O43184
Rat ADAM12 ADAM12 679837  

Show all synonyms

ADAM12 Proteins (ADAM12) by Origin

Select your origin of interest

Top referenced ADAM12 Proteins

  1. Human ADAM12 Protein expressed in HEK-293 Cells - ABIN2180562 : Iba, Albrechtsen, Gilpin, Fröhlich, Loechel, Zolkiewska, Ishiguro, Kojima, Liu, Langford, Sanderson, Brakebusch, Fässler, Wewer: The cysteine-rich domain of human ADAM 12 supports cell adhesion through syndecans and triggers signaling events that lead to beta1 integrin-dependent cell spreading. in The Journal of cell biology 2000 (PubMed)
    Show all 4 references for ABIN2180562

  2. Human ADAM12 Protein expressed in Human Cells - ABIN2003566 : Galliano, Huet, Frygelius, Polgren, Wewer, Engvall: Binding of ADAM12, a marker of skeletal muscle regeneration, to the muscle-specific actin-binding protein, alpha -actinin-2, is required for myoblast fusion. in The Journal of biological chemistry 2000 (PubMed)
    Show all 2 references for ABIN2003566

More Proteins for ADAM12 Interaction Partners

Mouse (Murine) ADAM Metallopeptidase Domain 12 (ADAM12) interaction partners

  1. ADAM12 and ADAM17 (show ADAM17 Proteins) are essential molecules for the impairment of barrier function of retinal vasculature under hypoxia.

  2. Augmentation of ADAM12 expression in vivo improved outcomes in Balb/c mice, whereas knockdown of ADAM12 made outcomes worse in C57Bl/6 mice. In vitro, ADAM12 expression modulates endothelial cell proliferation, survival, and angiogenesis.

  3. The effect of insulin-like growth factor-I (show IGF1 Proteins) on ADAM12 expression during the course of myogenesis is reported.

  4. Nitric oxide synthase deficiency has differential effects on ADAM12 expression in growing mouse brain.

  5. Inhibition of Erbb2 (show ERBB2 Proteins) suppressed the increase in metalloproteinase ADAM12 expression in skin tumors.

  6. TGF-beta (show TGFB1 Proteins) stimulation of renal cells results in a significant up-regulation of Adams 10, 17, 12, and 19

  7. ADAM12 enhanced ephrin-A1 (show EFNA1 Proteins) cleavage in response to transforming growth factor-betra1 in primary tumors.

  8. The endogenous SnoN (show SKIL Proteins) plays a role in regulating ADAM12 expression in response to TGFbeta1 (show TGFB1 Proteins).

  9. Adam12 is spatiotemporally expressed in decidualizing stromal cells in intact pregnant females and in pseudopregnant mice undergoing artificially induced decidualization.

  10. properly folded mouse ADAM12, after passing a rate-limiting step of exit from the ER, is processed in the secretory pathway and reaches the cell surface, where it can mediate adhesion-mediated signaling

Human ADAM Metallopeptidase Domain 12 (ADAM12) interaction partners

  1. The siRNA-directed loss of ADAM12 impedes spontaneous fusion of primary cytotrophoblasts, whereas overexpression of the secreted variant, ADAM12S, potentiates cell fusion in the Bewo trophoblast cell line.

  2. the present findings support the conclusion that the E2F1 transcription factor (show E2F1 Proteins) regulates the expression of ADAM12 by binding differential cis (show CISH Proteins)-acting elements.

  3. ADAM12L is associated with epithelial to mesenchymal transition (EMT (show ITK Proteins)) and contributes to TGF-beta (show TGFB1 Proteins)-dependent EMT (show ITK Proteins).

  4. ADAM33 (show ADAM33 Proteins) and ADAM12 genetic polymorphisms and their expression in Egyptian children with asthma

  5. Data suggest that low serum levels of ADAM12/hCG (show CGA Proteins) may be biomarkers in diagnosis of continued incomplete spontaneous abortion; here, ADAM12/hCG (show CGA Proteins) indicate success/failure of single dose of misoprostol/oxytocic in treatment of early pregnancy failure.

  6. The ADAM12-L 3'UTR is a direct target of miR (show MLXIP Proteins)-29 and miR (show MLXIP Proteins)-200 family members.

  7. High urine ADAM12 levels are associated with gastric cancer.

  8. Studied the potential role of four SNPs of the ADAM12 gene in susceptibility to knee osteoarthritis and its progression in Chinese Han population.

  9. There is a difference between the genders in response to an adverse maternal environment and suggest that an alteration in ADAM12 may reflect an altered placental response in pregnancies subsequently complicated by preeclampsia.

  10. ADAM12 expression is associated with an aggressive molecular subtype of high-grade serous ovarian carcinoma.High serum protein levels of ADAM12 are associated with poor survival in patients with high-grade serous ovarian carcinoma.

Cow (Bovine) ADAM Metallopeptidase Domain 12 (ADAM12) interaction partners

  1. These findings suggest ADAM12 is upregulated in muscles with more slow-oxidative myofibres, such as the LM, and is linked to type I myofibers in cattle.

  2. The 5'- and 3'-regions of bovive ADAM12 have been analysed and compared to the human gene, and the promoter region has been cloned and sequenced.

ADAM12 Protein Profile

Protein Summary

This gene encodes a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This gene has two alternatively spliced transcripts: a shorter secreted form and a longer membrane-bound form. The shorter form is found to stimulate myogenesis.

Alternative names and synonyms associated with ADAM12

  • ADAM metallopeptidase domain 12 (ADAM12)
  • a disintegrin and metalloproteinase domain 12 (meltrin alpha) (adam12)
  • ADAM metallopeptidase domain 12 (adam12)
  • a disintegrin and metallopeptidase domain 12 (meltrin alpha) (Adam12)
  • ADAM metallopeptidase domain 12 (Adam12)
  • adam12 protein
  • MCMP protein
  • MCMPMltna protein
  • mKIAA4001 protein
  • MLTN protein
  • MLTNA protein

Protein level used designations for ADAM12

ADAM metallopeptidase domain 12 , ADAM metallopeptidase domain 12 (meltrin alpha) , a disintegrin and metalloproteinase domain 12 (meltrin alpha) , adam12a , ADAM 12 , a disintegrin and metalloprotease domain 12 , disintegrin and metalloproteinase domain-containing protein 12 , meltrin alpha , meltrin-alpha , ADAM12 short isoform , disintegrin and metalloprotease 12 , a disintegrin and metallopeptidase domain 12 (meltrin alpha)

450818 Pan troglodytes
563275 Danio rerio
677729 Xenopus (Silurana) tropicalis
696405 Macaca mulatta
11489 Mus musculus
8038 Homo sapiens
425843 Gallus gallus
407229 Bos taurus
679837 Rattus norvegicus
100686018 Canis lupus familiaris
Selected quality suppliers for ADAM12 Proteins (ADAM12)
Did you look for something else?