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Browse our DAB2IP Proteins (DAB2IP)

Full name:
DAB2 Interacting Protein Proteins (DAB2IP)
On are 4 DAB2 Interacting Protein (DAB2IP) Proteins from 3 different suppliers available. Additionally we are shipping DAB2IP Antibodies (21) and many more products for this protein. A total of 25 DAB2IP products are currently listed.
2310011D08Rik, AF9Q34, AI480459, AIP-1, Aip1, dab2ip, DIP1/2, mKIAA1743, wu:fc08b07, wu:fk62h05
list all proteins Gene Name GeneID UniProt
DAB2IP 153090 Q5VWQ8
Rat DAB2IP DAB2IP 192126 Q6P730
DAB2IP 69601 Q3UHC7

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DAB2IP Proteins (DAB2IP) by Origin

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More Proteins for DAB2IP Interaction Partners

Human DAB2 Interacting Protein (DAB2IP) interaction partners

  1. DAB2IP could inhibit the phosphorylation and transactivation of STAT3 (show STAT3 Proteins), and then subsequently suppress the expression of Twist1 (show TWIST1 Proteins) and its target gene P-glycoprotein, both of which were crucial for the pirarubicin chemoresistance.

  2. Snail (show SNAI1 Proteins) and DAB2IP interact to regulate EMT (show ITK Proteins), invasion and metastasis in colorectal cancer

  3. High glucose increases AIP1 (show BIRC3 Proteins) expression and decreases the expression of HIF-1alpha (show HIF1A Proteins) and downstream molecules. Decreased HIF-1alpha (show HIF1A Proteins) signaling may be regulated by increased AIP1 (show BIRC3 Proteins) under high glucose.

  4. Immunohistochemical study exhibited an inverse correlation between DAB2IP and Skp2 protein expression in the prostate cancer tissue microarray.

  5. An inverse correlation between CD117 or ZEB1 and DAB2IP is also found in clinical specimens.

  6. miR (show MLXIP Proteins)-889 is an important regulator in ESCC and both miR (show MLXIP Proteins)-889 and DAB2IP may serve as promising biomarkers and therapeutic targets in patients with ESCC.

  7. Study showed that DAB2IP can be functionally inactivated by physical interaction with mutant p53 (show TP53 Proteins) proteins with implications for the response of cancer cells to inflammatory cytokines.

  8. our data indicate that a variety of pathways may pass through DAB2IP to govern cancer development

  9. downregulation of DAB2IP is associated with features of biologically aggressive urothelial carcinoma of the bladder and results in cell proliferation, migration, and invasion of bladder cancer.

  10. This study unveils a new regulation of the Egr-1 (show EGR1 Proteins)/Clusterin (show CLU Proteins) signaling network by DAB2IP. Loss of DAB2IP expression in CRPC cells signifies their chemoresistance

Pig (Porcine) DAB2 Interacting Protein (DAB2IP) interaction partners

  1. PP2A (show PPP2R2B Proteins) and AIP1 (show PDCD6IP Proteins) cooperatively induce activation of ASK1 (show MAP3K5 Proteins)-JNK (show MAPK8 Proteins) signaling and vascular endothelial cell apoptosis.

Mouse (Murine) DAB2 Interacting Protein (DAB2IP) interaction partners

  1. DAB2IP loss reprograms intracellular signal transduction and anti-apoptotic gene expression, which potentiates prostate cancer cell survival from androgen deprivation therapy-induced cell death.

  2. Germ cell-specific or Sertoli cell-specific deletion of Aip1 gene each led to significant defects in germ cell migration after postnatal day 4 or 5, accompanied by elevated levels of actin filaments (F-actin) in the affected cells.

  3. Cor1B, Cof1 and AIP1 work in concert through a temporally ordered pathway to induce highly efficient severing and disassembly of actin filaments.

  4. results suggest that Dab2IP plays an important role in the migration and positioning of a subpopulation of later-born (layers II-IV) neurons, likely through the regulation of Rap1 and integrin signaling.

  5. Our data reveal that AIP1 (show PDCD6IP Proteins), by inhibiting VEGFR2 (show KDR Proteins)-dependent signaling in tumor niche, suppresses tumor EMT (show ITK Proteins) switch, tumor angiogenesis, and tumor premetastatic niche formation to limit tumor growth and metastasis.

  6. AIP1 (show PDCD6IP Proteins) was elevated in the brain of AD Tg2576 mice. Abeta1-42 treatment induced the interaction of AIP1 (show PDCD6IP Proteins) and ASK1 (show MAP3K5 Proteins), which led to dissociation of ASK1 (show MAP3K5 Proteins) and 14-3-3 (show YWHAQ Proteins).

  7. site-specific methylation of mDab2ip gene during cerebellar development may play a role in inclusion of exon 5, resulting in a Dab2ip transcript variant that encodes a full pleckstrin (show PLEK Proteins) homology (PH) domain.

  8. Study showed that DAB2IP can be functionally inactivated by physical interaction with mutant p53 (show TP53 Proteins) proteins with implications for the response of cancer cells to inflammatory cytokines.

  9. DAB2IP is a unique intrinsic androgen receptor (show AR Proteins) modulator in normal cells, and likely can be further developed into a therapeutic agent for rpostate cancer.

  10. AIP1 (show PDCD6IP Proteins) knockouts have reduced retinal angiogenesis. Vascular endothelial cell (but not neuronal)-specific deletion of AIP1 (show PDCD6IP Proteins) causes similar defects. AIP1 (show PDCD6IP Proteins) via miR (show MLXIP Proteins)-1236 increases VEGFR-3 (show FLT4 Proteins) expression and binds it, enhancing endocytosis and stability.

DAB2IP Protein Profile

Protein Summary

DAB2IP is a Ras (MIM 190020) GTPase-activating protein (GAP) that acts as a tumor suppressor. The DAB2IP gene is inactivated by methylation in prostate and breast cancers (Yano et al., 2005

Alternative names and synonyms associated with DAB2IP

  • DAB2 interacting protein (DAB2IP)
  • DAB2 interacting protein b (dab2ipb)
  • DAB2 interacting protein (dab2ip)
  • DAB2 interacting protein (Dab2ip)
  • disabled 2 interacting protein (Dab2ip)
  • 2310011D08Rik protein
  • AF9Q34 protein
  • AI480459 protein
  • AIP-1 protein
  • Aip1 protein
  • dab2ip protein
  • DIP1/2 protein
  • mKIAA1743 protein
  • wu:fc08b07 protein
  • wu:fk62h05 protein

Protein level used designations for DAB2IP

DAB2 interacting protein , ASK-interacting protein 1 , ASK1-interacting protein 1 , DAB2 interaction protein , DAB2-interacting protein , DOC-2/DAB-2 interactive protein , DOC-2/DAB2 interactive protein , disabled homolog 2-interacting protein , nGAP-like protein , apoptosis signal-regulating kinase 1-interacting protein 1 , disabled homolog 2 interacting protein , DOC2/DAB2 interactive protein , disabled 2 interacting protein long form

100071680 Equus caballus
417117 Gallus gallus
558237 Danio rerio
699080 Macaca mulatta
100081752 Ornithorhynchus anatinus
100145038 Xenopus (Silurana) tropicalis
100591971 Nomascus leucogenys
153090 Homo sapiens
491356 Canis lupus familiaris
100286868 Sus scrofa
541268 Bos taurus
192126 Rattus norvegicus
100719421 Cavia porcellus
69601 Mus musculus
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