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Human Mesothelin ELISA Kit for Sandwich ELISA - ABIN423233
Bostanc?, Kemik, Kemik, Battal, Demir, Purisa, Yavuz, Mihmanl?: Preoperative serum levels of mesothelin in patients with colon cancer. in Disease markers 2014
These clinical data showed that the expression of G-protein coupled estrogen receptor (show ESR1 ELISA Kits) (GPER (show GPER ELISA Kits)) is negatively associated with lymph node metastasis, high-grade tumor and fibronectin (FN (show FN1 ELISA Kits)) expression while positively associated with the favorable outcome in 135 triple negative breast cancer cells patients.
Data suggest that, under agonism of estrogens, ESR1 (show ESR1 ELISA Kits) exhibits a generally anxiogenic effect, ESR2 (show ESR2 ELISA Kits) exhibits a generally anxiolytic effect, and GPR30 (show GPER ELISA Kits) exhibits both anxiogenic and anxiolytic effects. (ESR1 (show ESR1 ELISA Kits) = estrogen receptor 1/alpha (show ESR1 ELISA Kits); ESR2 (show ESR2 ELISA Kits) = estrogen receptor 2/beta (show ESR2 ELISA Kits); GPR30 (show GPER ELISA Kits) = G protein-coupled estrogen receptor 1 (show GPER ELISA Kits)) [REVIEW]
Either by specific inhibitors for GPER (show GPER ELISA Kits), ERK (show EPHB2 ELISA Kits), AKT (show AKT1 ELISA Kits) and NF-kappaB (show NFKB1 ELISA Kits), or by knock-down of GPER (show GPER ELISA Kits).
The intron variant rs4265085 of GPER1 may confer risk for recurrent spontaneous abortion in Dai and Bai ethnic groups in China.
Mesothelin/mucin 16 (show MUC16 ELISA Kits) signaling in activated portal fibroblasts regulates cholestatic liver fibrosis.(
MiR (show MLXIP ELISA Kits)-21-5p is suggested as novel regulator of MSLN with a possible functional role in cellular growth.
Activation of GPER (show GPER ELISA Kits) can suppress migration and angiogenesis of triple negative breast cancer by inhibiting of NF-kappaB (show NFKB1 ELISA Kits)/IL-6 (show IL6 ELISA Kits) signaling.
we report herein that high tumor mesothelin expression predicts a shorter PFS and OS in EOC patients and demonstrates that serum mesothelin predicts local tumor mesothelin expression.
GPER (show GPER ELISA Kits) protects against hepatic tumorigenesis by regulating inflammatory responses.
We provide new evidence for the role of MSLN in EMT (show ITK ELISA Kits) regulation, tumorigenesis and metastasis. Knockdown of MSLN led to mesenchymal to epithelial transition and less aggressive behavior of lung carcinoma and mesothelioma cells.
These findings provide strong evidence for aldosterone serving a causal role in renal cell cancer regulation via its GPER (show GPER ELISA Kits) receptor; thus, antagonism of GPER (show GPER ELISA Kits) represents a potential new target for treatment to reduce metastatic spread.
Data suggest that prenatal exposure to p,p'-DDT (show DDT ELISA Kits) (an endocrine disrupting pesticide) causes sex- and age-independent attenuation of Gper1 in brain which appears to play key role in propagation of DDT (show DDT ELISA Kits)-induced depressive-like neurotoxicity.
Study suggested that the neuroprotective effect of estrogen requires intact GPER1-associated signaling in an in vitro model of ischemia. The membrane-associated signaling mediates the estrogen actions, and depends on PI3K/Akt (show AKT1 ELISA Kits) signaling for Ask1 (show MAP3K5 ELISA Kits) inhibition that prevents the cell death triggered by ischemia. These mechanisms may help for a therapeutic strategy to target on GPER1 for the treatment of neurological disorders.
Phosphorylation of myosin regulatory light chain triggered by E2 was found to be mediated by estrogen receptor-beta (show ESR2 ELISA Kits) and the G protein-coupled estrogen receptor (show ESR1 ELISA Kits).
Our study demonstrated the ameliorative role of GPR30 (show GPER ELISA Kits) in NOR memory impaired by AD pathology in female mice
identified a novel regulatory mechanism through which the endogenous Gper (show GPER ELISA Kits) facilitates the age-dependent increase in myocardial expression of ECE-2 (show ECE2 ELISA Kits) and the ETB (show EDNRB ELISA Kits) receptor, which is compatible with an activating role of GPER (show GPER ELISA Kits) for the local endothelin system with aging
We suggest that activation of GPER (show GPER ELISA Kits) exerts an inhibitory effect on colonic motility by promoting nitric oxide release from myenteric nitrergic nerves
GPR30 (show GPER ELISA Kits) is expressed in diverse intracellular compartments in undifferentiated and differentiated C2C12 cells and mediates estradiol actions.
This gene encodes a precursor protein that is cleaved into two products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiation factor functions as a cytokine that can stimulate colony formation in bone marrow megakaryocytes. Mesothelian is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants.
, megakaryocyte potentiating factor
, pre-pro-megakaryocyte-potentiating factor
, soluble MPF mesothelin related protein
, G protein-coupled receptor 30
, G-protein coupled estrogen receptor 1
, G-protein coupled receptor 30
, chemoattractant receptor-like 2
, constitutively expressed peptide-like receptor like
, membrane estrogen receptor
, protein expressed in renal carcinoma