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Browse our SOX9 Proteins (SOX9)

Full name:
SRY (Sex Determining Region Y)-Box 9 Proteins (SOX9)
On are 16 SRY (Sex Determining Region Y)-Box 9 (SOX9) Proteins from 7 different suppliers available. Additionally we are shipping SOX9 Antibodies (183) and SOX9 Kits (39) and many more products for this protein. A total of 247 SOX9 products are currently listed.
2010306G03Rik, AV220920, CMD1, CMPD1, LOC100227849, mKIAA4243, SOX-9, SOX9, SRA1
list all proteins Gene Name GeneID UniProt
SOX9 6662 P48436
Rat SOX9 SOX9 140586  
SOX9 20682 Q04887

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SOX9 Proteins (SOX9) by Origin

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More Proteins for SOX9 Interaction Partners

Human SRY (Sex Determining Region Y)-Box 9 (SOX9) interaction partners

  1. Variability has been found in a three-generation family with Pierre Robin sequence, acampomelic campomelic dysplasia, and intellectual disability due to a novel approximately 1 Mb deletion upstream of SOX9, and including KCNJ2 (show KCNJ2 Proteins) and KCNJ16 (show KCNJ16 Proteins).

  2. Overexpression of TGF-beta (show TGFB1 Proteins) and sox9 enhanced the levels of cell proliferation, matrix biosynthesis, and chondrogenic differentiation in human mesenchymal stem cells.

  3. SOX9 expression was commonly upregulated in glioma tissues, and patients with high SOX9 levels had shorter survival times.

  4. Sox9 overexpression in intrahepatic cholangiocarcinoma is related to biliary infiltration and poorer prognosis, and it promotes cell migration and invasion, via the epithelial-to-mesenchymal transition.

  5. SOX9 upregulation might mediate A disintegrin and metalloproteinase with thrombospondin motifs (ADAMTSs) suppression at the early stage of human osteoarthritis. In addition, SOX9 could be used as a potential therapeutic agent for human osteoarthritis at an early stage.

  6. Upregulation of sex-determining region Y (show SRY Proteins)-box 9 promotes cell proliferation and tumorigenicity in esophageal squamous cell carcinoma.

  7. Our study shows an inversed preferential nuclear expression of SLUG (show SNAI2 Proteins), SOX10 (show SOX10 Proteins), and SOX9 in triple negative and non-triple negative cases.

  8. MicroRNA-494 inhibits cell proliferation and invasion of chondrosarcoma cells in vivo and in vitro by down-regulating SOX9 expression.

  9. Results suggest that SOX9 promotes tumor metastasis and invasion through regulation of S100P (show S100P Proteins) expression in colon cancer.

  10. Chromatin immunoprecipitation analysis revealed interaction between SOX9 and the specific region of the p21WAF1/CIP1 promoter. Data suggest that SOX9 is a potential therapeutic target in cervical carcinoma, that transactivates p21WAF1/CIP1.

Pig (Porcine) SRY (Sex Determining Region Y)-Box 9 (SOX9) interaction partners

  1. data presented here demonstrate that the 18 bp indel in the porcine SOX9 5'-UTR is of functional importance and may therefore indeed be a causative variation in SOX9 associated traits

  2. HIF-1alpha (show HIF1A Proteins) activates Sox9 expression and enhances Sox9-mediated transcriptional activity.

Mouse (Murine) SRY (Sex Determining Region Y)-Box 9 (SOX9) interaction partners

  1. Although transgenic Sox9 overexpression in the absence of Sry (show SRY Proteins) results in certain testicular abnormalities, it does not translate into fertility impairment.

  2. Rspo2 (show RSPO2 Proteins) activates Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) signaling to reduce Col2a1 (show COL2A1 Proteins) and Sox9 and to facilitate differentiation of proliferating chondrocytes into hypertrophic chondrocytes in growth cartilage

  3. The Sox9 protein HMG (show SSRP1 Proteins) domain was identified through crystallization and DNA CHIP sequence.

  4. Data show significant increase in Sox9 protein but not mRNA, and a signifcant decrease in miR (show MLXIP Proteins)-101 levels in the mouse lung after acute lung injury and highlight the critical role of miR (show MLXIP Proteins)-101-regulated Sox9 in the lung recovery.

  5. Astrocyte induction by Zbtb20 (show ZBTB20 Proteins) is suppressed by knockdown of Sox9.

  6. Sox9 and Pdx1 (show PDX1 Proteins) bind to regulatory sequences near pancreatic and intestinal differentiation genes and jointly regulate their expression.

  7. We observed that tranilast increased mRNA expression of both Sox9 and Runx2 (show RUNX2 Proteins) in differentiating ATDC5 chondrogenic progenitor cells.

  8. Sox9 is required for a normal epithelial repair process after acute kidney injury.

  9. Results show that Sox9, Sox5 (show SOX5 Proteins), and Sox13 (show SOX13 Proteins) transcription factors are expressed in postnatal testis and may regulate multiple functions such as steroidogenesis and spermatogenesis.

  10. Aortic valve endothelial cell derived Tgfb1 (show TGFB1 Proteins) signaling promotes nuclear localization of Sox9 in interstitial cells, attenuating aortic valve calcification.

SOX9 Protein Profile

Protein Summary

The protein encoded by this gene recognizes the sequence CCTTGAG along with other members of the HMG-box class DNA-binding proteins. It acts during chondrocyte differentiation and, with steroidogenic factor 1, regulates transcription of the anti-Muellerian hormone (AMH) gene. Deficiencies lead to the skeletal malformation syndrome campomelic dysplasia, frequently with sex reversal.

Alternative names and synonyms associated with SOX9

  • SRY (sex determining region Y)-box 9 (SOX9)
  • SRY (sex determining region Y)-box 9 (LOC100227849)
  • SRY (sex determining region Y)-box 10 (SOX10)
  • SRY (sex determining region Y)-box 9 (Sox9)
  • SRY-box containing gene 9 (Sox9)
  • 2010306G03Rik protein
  • AV220920 protein
  • CMD1 protein
  • CMPD1 protein
  • LOC100227849 protein
  • mKIAA4243 protein
  • SOX-9 protein
  • SOX9 protein
  • SRA1 protein

Protein level used designations for SOX9

SRY (sex determining region Y)-box 9 , SRY (sex determining region Y)-box 9 (campomelic dysplasia, autosomal sex-reversal) , transcription factor SOX-10 , SRY (sex-determining region Y)-box 9 protein , SRY-related HMG-box, gene 9 , transcription factor SOX-9 , SRY-box containing protein 9 , SRY-box containing gene 9 , transcription factor SOX9

100452528 Pongo abelii
100227849 Taeniopygia guttata
353115 Bos taurus
6662 Homo sapiens
374148 Gallus gallus
403464 Canis lupus familiaris
140586 Rattus norvegicus
396840 Sus scrofa
450101 Pan troglodytes
574208 Macaca mulatta
20682 Mus musculus
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