Browse our SOX9 Proteins (SOX9)

On www.antibodies-online.com are 15 SRY (Sex Determining Region Y)-Box 9 (SOX9) Proteins from 6 different suppliers available. Additionally we are shipping SOX9 Antibodies (208) and SOX9 Kits (34) and many more products for this protein. A total of 268 SOX9 products are currently listed.
Synonyms:
2010306G03Rik, AV220920, CMD1, CMPD1, LOC100227849, mKIAA4243, SOX-9, SOX9, SRA1
list all proteins Gene Name GeneID UniProt
SOX9 6662 P48436
Rat SOX9 SOX9 140586  
SOX9 20682 Q04887

SOX9 Proteins (SOX9) by Origin

More Proteins for SOX9 Interaction Partners

Human SRY (Sex Determining Region Y)-Box 9 (SOX9) interaction partners

  1. These findings suggest that SOX9 may play an important role in tumor progression of Renal Cell Carcinoma (show MOK Proteins) and Bladder Cancer and it may be used as a biomarker of this malignancy.

  2. Loss of DDRGK1 decreases SOX9 expression and causes a human skeletal dysplasia.

  3. The expression of EVI1 (show MECOM Proteins) and SOX9 is associated with stem cell-like and metastasis signatures, and their depletion impairs the metastatic potential of breast cancer cells. These results establish the mechanistic link between resistance to mTOR (show FRAP1 Proteins) inhibition and cancer metastatic potential, thus enhancing our understanding of mTOR (show FRAP1 Proteins) targeting failure

  4. regulation of cancer stem cell via SLUG (show SNAI2 Proteins)-SOX9 regulatory axis

  5. data indicate that SOX9 expression drives prostate cancer by reactivating the WNT (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) signaling that mediates ductal morphogenesis in fetal prostate and define a subgroup of patients who would benefit from WNT (show WNT2 Proteins)-targeted therapy.

  6. Low levels of SOX9 in primary stage II colon tumors predicts high risk of relapse.

  7. ELF3 interacts directly with the HMG domain of Sox9. Importantly, overexpression of ELF3 significantly decreased Sox9/CBP-dependent HAT activity.

  8. SOX9 is required for chondrogenesis: it secures chondrocyte lineage commitment, promotes cell survival, and transcriptionally activates the genes for many cartilage-specific structural components and regulatory factors.

  9. SOX9 is almost exclusively expressed by astrocytes in the adult brain except for ependymal cells and in the neurogenic regions, where SOX9 is also expressed by neural progenitor cells

  10. These findings indicate that chronic overexpression of Sox9 in the uterine epithelium can induce the development of endometrial hyperplastic lesions. Thus, SOX9 expression may be a factor in the formation of endometrial cancer.

Pig (Porcine) SRY (Sex Determining Region Y)-Box 9 (SOX9) interaction partners

  1. data presented here demonstrate that the 18 bp indel in the porcine SOX9 5'-UTR is of functional importance and may therefore indeed be a causative variation in SOX9 associated traits

  2. HIF-1alpha (show HIF1A Proteins) activates Sox9 expression and enhances Sox9-mediated transcriptional activity.

Mouse (Murine) SRY (Sex Determining Region Y)-Box 9 (SOX9) interaction partners

  1. Sox9 is positively regulated by mesenchymal Fgf10 (show FGF10 Proteins), a process that requires active Erk (show EPHB2 Proteins) signaling during salivary gland development

  2. TSC1 (show TSC1 Proteins)/TSC2 complex upregulation of OPN (show SPP1 Proteins) expression is mediated by transcription factor SOX9 in an mTOR (show FRAP1 Proteins)-independent manner. Moreover, ablation of OPN (show SPP1 Proteins) by deficient TSC1 (show TSC1 Proteins)/TSC2 complex contributed to inactivation of AKT (show AKT1 Proteins) in TSC (show SLC12A3 Proteins) cells

  3. SOX9 is almost exclusively expressed by astrocytes in the adult brain except for ependymal cells and in the neurogenic regions, where SOX9 is also expressed by neural progenitor cells

  4. hese findings indicate that chronic overexpression of Sox9 in the uterine epithelium can induce the development of endometrial hyperplastic lesions. Thus, SOX9 expression may be a factor in the formation of endometrial cancer.

  5. The conditional ablation of Sox9 in the genital tubercle using Shh (show SHH Proteins)-Cre/+;Sox9(flox/flox) mice revealed no genital tubercle abnormalities, possibly due to compensation by similar Sox (show QSOX1 Proteins) factors.

  6. The level of SOX9 protein in the kidneys of acute kidney injury-mice is reduced and correlates inversely with increased expression of microRNA miR (show MLXIP Proteins)-1247.

  7. Results show that SOX9, a key transcription factor involved in chondrogenesis, regulates Smpd3 (show SMPD3 Proteins) expression in chondrogenic cells.

  8. These findings suggest a novel mechanism of action of SOX5 (show SOX5 Proteins)/6; namely, the SOX9/5/6 combination enhances Col2a1 (show COL2A1 Proteins) transcription through a novel enhancer in intron 6 together with the enhancer in intron 1.

  9. These findings illuminate a novel role for Stat3 (show STAT3 Proteins) in chondrocytes during skeletal development through modulation of a critical factor, Sox9. Importantly, they further provide the first evidence for the modulation of a gene product other than Sox9 itself which is capable of modeling pathological aspects of CD and underscore a potentially valuable therapeutic target for patients with the disorder.

  10. Intact TES (show TES Proteins)/TESCO is required for directing appropriate Sox9 expression levels in the testis.

SOX9 Protein Profile

Protein Summary

The protein encoded by this gene recognizes the sequence CCTTGAG along with other members of the HMG-box class DNA-binding proteins. It acts during chondrocyte differentiation and, with steroidogenic factor 1, regulates transcription of the anti-Muellerian hormone (AMH) gene. Deficiencies lead to the skeletal malformation syndrome campomelic dysplasia, frequently with sex reversal.

Alternative names and synonyms associated with SOX9

  • SRY (sex determining region Y)-box 9 (SOX9)
  • SRY (sex determining region Y)-box 9 (LOC100227849)
  • SRY (sex determining region Y)-box 10 (SOX10)
  • SRY (sex determining region Y)-box 9 (Sox9)
  • SRY-box containing gene 9 (Sox9)
  • 2010306G03Rik protein
  • AV220920 protein
  • CMD1 protein
  • CMPD1 protein
  • LOC100227849 protein
  • mKIAA4243 protein
  • SOX-9 protein
  • SOX9 protein
  • SRA1 protein

Protein level used designations for SOX9

SRY (sex determining region Y)-box 9 , SRY (sex determining region Y)-box 9 (campomelic dysplasia, autosomal sex-reversal) , transcription factor SOX-10 , SRY (sex-determining region Y)-box 9 protein , SRY-related HMG-box, gene 9 , transcription factor SOX-9 , SRY-box containing protein 9 , SRY-box containing gene 9 , transcription factor SOX9

GENE ID SPECIES
100452528 Pongo abelii
100227849 Taeniopygia guttata
353115 Bos taurus
6662 Homo sapiens
374148 Gallus gallus
403464 Canis lupus familiaris
140586 Rattus norvegicus
396840 Sus scrofa
450101 Pan troglodytes
574208 Macaca mulatta
20682 Mus musculus
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