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Browse our SOX9 Proteins (SOX9)

Full name:
SRY (Sex Determining Region Y)-Box 9 Proteins (SOX9)
On www.antibodies-online.com are 15 SRY (Sex Determining Region Y)-Box 9 (SOX9) Proteins from 6 different suppliers available. Additionally we are shipping SOX9 Antibodies (187) and SOX9 Kits (34) and many more products for this protein. A total of 247 SOX9 products are currently listed.
Synonyms:
2010306G03Rik, AV220920, CMD1, CMPD1, LOC100227849, mKIAA4243, SOX-9, SOX9, SRA1
list all proteins Gene Name GeneID UniProt
SOX9 6662 P48436
Rat SOX9 SOX9 140586  
SOX9 20682 Q04887

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SOX9 Proteins (SOX9) by Origin

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Top referenced SOX9 Proteins

  1. Human SOX9 Protein expressed in HEK-293 Cells - ABIN2732475 : Shi, Chiang, Labhart, Zhao, Yang, Mistretta, Henning, Maity, Mori-Akiyama: Context-specific role of SOX9 in NF-Y mediated gene regulation in colorectal cancer cells. in Nucleic acids research 2015 (PubMed)

More Proteins for SOX9 Interaction Partners

Human SRY (Sex Determining Region Y)-Box 9 (SOX9) interaction partners

  1. Our data proved that RMRP (show NME1 Proteins) acted as an oncogene (show RAB1A Proteins) LncRNA to promote the expression of KRAS, FMNL2 (show FMNL2 Proteins) and SOX9 by inhibiting miR (show MLXIP Proteins)-206 expression in lung cancer. These data suggested that RMRP (show NME1 Proteins) might serve as a therapeutic target in lung adenocarcinoma

  2. FOXK2 (show FOXK2 Proteins) and SOX9 expression are correlated in colorectal cancer tissues.FOXK2 is transcriptional activated by SOX9.

  3. SR4 activity and the observed SOX9 expression pattern suggest that (show SHH Proteins) SR4 may function as a Sox9 genital tubercle enhancer.

  4. the signaling pathway study confirmed that Sox9 protected MRC-5 from lipopolysaccharide injury through the AKT/GSK3beta pathway.

  5. deacetylation promotes SOX9 nuclear translocation and hence its ability to activate ACAN (show ACAN Proteins).

  6. Our findings reveal a novel regulatory mechanism for SOX9 stability and uncover a unique function of SOX9 in the cellular response to DNA damage. This new mechanism underlying a FBW7 (show FBXW7 Proteins)-SOX9 axis in cancer could have implications in therapy resistance.

  7. These findings suggest a novel mechanism of action of SOX5 (show SOX5 Proteins)/6; namely, the SOX9/5/6 combination enhances Col2a1 (show COL2A1 Proteins) transcription through a novel enhancer in intron 6 together with the enhancer in intron 1.

  8. ZNF606 (show ZNF606 Proteins) prevents Sox9 binding to the enhancers of its target gene col2a1 (show COL2A1 Proteins). Importantly, the interaction between ZNF606 (show ZNF606 Proteins) and Sox9 was decreased during chondrocyte differentiation.

  9. Chemical suppression of the proteasome rescued the effect of LNA30bcd on SOX9 protein levels, indicating that the regulation of SOX9 protein by miR (show MLXIP Proteins)-30 is largely indirect through the proteasome pathway. Inhibition of the miR (show MLXIP Proteins)-30 family led to significantly reduced IEC proliferation and a dramatic increase in markers of enterocyte differentiation.

  10. miR (show MLXIP Proteins)-105 functions as a potential tumor suppressor by regulating the SOX9/TCF4 (show TCF4 Proteins) axis in glioma

Pig (Porcine) SRY (Sex Determining Region Y)-Box 9 (SOX9) interaction partners

  1. data presented here demonstrate that the 18 bp indel in the porcine SOX9 5'-UTR is of functional importance and may therefore indeed be a causative variation in SOX9 associated traits

  2. HIF-1alpha (show HIF1A Proteins) activates Sox9 expression and enhances Sox9-mediated transcriptional activity.

Mouse (Murine) SRY (Sex Determining Region Y)-Box 9 (SOX9) interaction partners

  1. The conditional ablation of Sox9 in the genital tubercle using Shh (show SHH Proteins)-Cre/+;Sox9(flox/flox) mice revealed no genital tubercle abnormalities, possibly due to compensation by similar Sox (show QSOX1 Proteins) factors.

  2. The level of SOX9 protein in the kidneys of acute kidney injury-mice is reduced and correlates inversely with increased expression of microRNA miR (show MLXIP Proteins)-1247.

  3. Results show that SOX9, a key transcription factor involved in chondrogenesis, regulates Smpd3 (show SMPD3 Proteins) expression in chondrogenic cells.

  4. These findings suggest a novel mechanism of action of SOX5 (show SOX5 Proteins)/6; namely, the SOX9/5/6 combination enhances Col2a1 (show COL2A1 Proteins) transcription through a novel enhancer in intron 6 together with the enhancer in intron 1.

  5. These findings illuminate a novel role for Stat3 (show STAT3 Proteins) in chondrocytes during skeletal development through modulation of a critical factor, Sox9. Importantly, they further provide the first evidence for the modulation of a gene product other than Sox9 itself which is capable of modeling pathological aspects of CD and underscore a potentially valuable therapeutic target for patients with the disorder.

  6. Intact TES (show TES Proteins)/TESCO is required for directing appropriate Sox9 expression levels in the testis.

  7. Chemical suppression of the proteasome rescued the effect of LNA30bcd on SOX9 protein levels, indicating that the regulation of SOX9 protein by miR (show MLXIP Proteins)-30 is largely indirect through the proteasome pathway. Inhibition of the miR (show MLXIP Proteins)-30 family led to significantly reduced IEC proliferation and a dramatic increase in markers of enterocyte differentiation.

  8. Perlecan (show HSPG2 Proteins) is required for the chondrogenic and adipogenic differentiation from SMCs via its regulation of the Sox9 and PPARgamma (show PPARG Proteins) gene expression, but not for osteogenic differentiation via Runx2 (show RUNX2 Proteins)

  9. Differences in the pattern of expression of Sox9 in limbs of avian, mouse and turtle embryos may reflect signaling differences associated with distinct limb skeletal morphologies observed in these species.

  10. These results suggest that improved recovery of locomotor function in Sox9 conditional knock out mice after SCI is due to increased reactive sprouting secondary to reduced CSPG levels distal to the lesion.

SOX9 Protein Profile

Protein Summary

The protein encoded by this gene recognizes the sequence CCTTGAG along with other members of the HMG-box class DNA-binding proteins. It acts during chondrocyte differentiation and, with steroidogenic factor 1, regulates transcription of the anti-Muellerian hormone (AMH) gene. Deficiencies lead to the skeletal malformation syndrome campomelic dysplasia, frequently with sex reversal.

Alternative names and synonyms associated with SOX9

  • SRY (sex determining region Y)-box 9 (SOX9)
  • SRY (sex determining region Y)-box 9 (LOC100227849)
  • SRY (sex determining region Y)-box 10 (SOX10)
  • SRY (sex determining region Y)-box 9 (Sox9)
  • SRY-box containing gene 9 (Sox9)
  • 2010306G03Rik protein
  • AV220920 protein
  • CMD1 protein
  • CMPD1 protein
  • LOC100227849 protein
  • mKIAA4243 protein
  • SOX-9 protein
  • SOX9 protein
  • SRA1 protein

Protein level used designations for SOX9

SRY (sex determining region Y)-box 9 , SRY (sex determining region Y)-box 9 (campomelic dysplasia, autosomal sex-reversal) , transcription factor SOX-10 , SRY (sex-determining region Y)-box 9 protein , SRY-related HMG-box, gene 9 , transcription factor SOX-9 , SRY-box containing protein 9 , SRY-box containing gene 9 , transcription factor SOX9

GENE ID SPECIES
100452528 Pongo abelii
100227849 Taeniopygia guttata
353115 Bos taurus
6662 Homo sapiens
374148 Gallus gallus
403464 Canis lupus familiaris
140586 Rattus norvegicus
396840 Sus scrofa
450101 Pan troglodytes
574208 Macaca mulatta
20682 Mus musculus
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