Browse our NRF2 (NFE2L2) ELISA Kits

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Nuclear Factor (erythroid-Derived 2)-Like 2 ELISA Kits (NFE2L2)
On are 50 Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2) ELISA Kits from 15 different suppliers available. Additionally we are shipping NRF2 Antibodies (212) and NRF2 Proteins (10) and many more products for this protein. A total of 282 NRF2 products are currently listed.
AI194320, NF-E2R2, nfe2l2, NRF2, wu:fc15g09, wu:fj67e03
list all ELISA KIts Gene Name GeneID UniProt
NFE2L2 4780 Q16236
NFE2L2 18024 Q60795
NFE2L2 83619 O54968

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More ELISA Kits for NRF2 Interaction Partners

Zebrafish Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2) interaction partners

  1. These data suggest that EC from the Tripterygium wilfordii stem extract could diminish tau-GFP-induced neuronal death through the activation of Nrf2.

  2. we concluded that Nrf2 plays a fundamental and conserved role in protection against acute sodium arsenite toxicity

  3. Coptisine exerted its antioxidant activity against AAPH-induced toxicity involving in activating Akt (show AKT1 ELISA Kits) and JNK (show MAPK8 ELISA Kits)/Nrf2/NQO1 (show NQO1 ELISA Kits) pathway.

  4. Bach1 (show BACH1 ELISA Kits) regulates the liver specificity and transience of the Nrf2a-dependent induction of hmox1a and that heme mediates this regulation through Bach1 (show BACH1 ELISA Kits) inhibition based on its level in each tissue.

  5. The Bach1b-MafK heterodimer represses the zymogen promoters, whereas the Nrf2a-MafK heterodimer activates them.

  6. The expression of nrf (show NRF1 ELISA Kits) genes varies temporally throughout development and nrf (show NRF1 ELISA Kits) genes are induced following a pro-oxidant exposure and are potentially cross-regulated by gene family members Nrf2a and Nrf2b (show GABPb ELISA Kits).

  7. oxidative stress is an important mechanism of Cd-mediated injury in the zebrafish olfactory system; the Nrf2 pathway plays a protective role against cellular oxidative damage and is important in maintaining zebrafish olfactory function.

  8. results revealed that nrf2 mutant zebrafish are viable and fertile but show an increased susceptibility to oxidative stress and electrophiles

  9. compared the tissue-specific expression of several Nrf2 target genes in zebrafish larvae; Tissue-restricted induction was observed in the nose, gill, and/or liver for seven genes in response to Nrf2-activating compounds

  10. Nrf2 is protective against PFOS-induced oxidative stress in zebrafish larvae.

Cow (Bovine) Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2) interaction partners

  1. These findings suggest that bronchiolar epithelial cells and macrophages up-regulate Nrf2 expression early in the course of infection, which results in increased expression of HO-1 (show HMOX1 ELISA Kits) within these cells.

  2. the survival and developmental competence of embryos cultured under oxidative stress are associated with activity of the NRF2-mediated oxidative stress response pathway during bovine pre-implantation embryo development.

  3. investigation of molecular mechanisms of microvascular complications in diabetes/hyperglycemia: Nrf2 is involved in regulation of HO-1 (show HMOX1 ELISA Kits) gene expression in aortic endothelial cells by advanced glycation end products

Pig (Porcine) Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2) interaction partners

  1. Lack of Nrf2 enhances susceptibility to mycotoxin-induced kidney disease.

  2. The effects of ochratoxin A on the nuclear translocation and transactivation of the transcription factor Nrf2 as well as mRNA levels of Nrf2 target genes are reported.

Human Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2) interaction partners

  1. inflammatory cytokines promoted Nrf2 (show GABPA ELISA Kits) nuclear translocation in psoriatic epidermis, which led to elevated expression of K6, K16 (show KRT16 ELISA Kits), and K17 (show KRT17 ELISA Kits), thus promoting keratinocyte proliferation and contributing to the pathogenesis of psoriasis.

  2. The two compounds were shown to induce apoptosis and inhibit the Nrf2 (show GABPA ELISA Kits)/ARE signaling pathway in Hep3B cells.

  3. Reduced mRNA expression of NFE2L2 is associated with breast cancer.

  4. Data (including data from studies using cells from knockout mice) confirm that the NRF2 (show GABPA ELISA Kits)/HMOX1 (show HMOX1 ELISA Kits) axis is a critical pathway in the hyperglycemic-mediated dysregulation and inflammatory features of chondrocytes in type 2 diabetes-associated osteoarthritis. (NRF2 (show GABPA ELISA Kits) = nuclear factor [erythroid-derived 2]-like 2 protein; HMOX1 (show HMOX1 ELISA Kits) = heme oxygenase (show HMOX1 ELISA Kits) [decycling] 1)

  5. This study demonstrates that Nrf2 (show GABPA ELISA Kits) could be an ideal druggable target in AML (show RUNX1 ELISA Kits), more so to the drugs that function through ROS (show ROS1 ELISA Kits), suggesting the possibility of using Nrf2 (show GABPA ELISA Kits) inhibitors in combination with chemotherapeutic agents to modulate drug resistance in AML (show RUNX1 ELISA Kits).

  6. -rich DNA causes a prolonged increase in mRNA levels of NF-kB and NRF2 (show GABPA ELISA Kits) which lasts 48 and 24 h, respectively.

  7. examination of plant (show GABPA ELISA Kits)ar skin b (show KRT16 ELISA Kits)iopsies from individuals with pachyonychia congenita confirmed the presence of (show GABPA ELISA Kits) high levels of hypophosphorylated NRF2 in lesional tissue

  8. SIRT2 (show SIRT2 ELISA Kits) maintains cellular iron levels by binding to and deacetylating nuclear factor erythroid-derived 2 (show NFE2 ELISA Kits)-related factor 2 (NRF2 (show GABPA ELISA Kits)) on lysines 506 and 508, leading to a reduction in total and nuclear NRF2 (show GABPA ELISA Kits) levels.

  9. basal function of NRF2 (show GABPA ELISA Kits) in colorectal cancer

  10. NRF2 (show GABPA ELISA Kits) is regulated at protein level by proteasomal degradation via KEAP1 (show KEAP1 ELISA Kits). Data suggest that antioxidant-induced up-regulation of NRF2 (show GABPA ELISA Kits) expression (a) overcomes KEAP1 (show KEAP1 ELISA Kits) regulation, (b) activates NRF2 (show GABPA ELISA Kits) translocation to nucleus, and (c) activates antioxidant response element. (NRF2 (show GABPA ELISA Kits) = nuclear factor [erythroid-derived 2]-like 2 protein; KEAP1 (show KEAP1 ELISA Kits) = Kelch-like ECH-associated protein 1 (show KEAP1 ELISA Kits))

Mouse (Murine) Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2) interaction partners

  1. These results suggest that the Keap1 (show KEAP1 ELISA Kits)/Nrf2 axis plays a critical role in NFATc1 (show NFATC1 ELISA Kits) expression and osteoclastogenic progression.

  2. Low NRF2 expression is associated with progression of hepatic fibrosis.

  3. Findings show that NRF2 drives the cell cycle entry and differentiation of long-term hematopoietic stem cells at the expense of their quiescence and maintenance, an effect that appears to be beneficial for prompt recovery from blood loss. Study proposes that the appropriate control of NRF2 activity by KEAP1 (show KEAP1 ELISA Kits) is essential for maintaining HSCs and guarantees their stress-induced regenerative response.

  4. The studies tested the role of Nrf2 during Streptococcus pneumoniae pneumonia and identified Nrf2-dependent genes and pathways in lung tissue and in recruited neutrophils.

  5. results provide mechanistic insight into Nrf2 action in the control of inflammation and cell proliferation through regulation of a proinflammatory cytokine with a key function in various inflammatory diseases

  6. Systemic NRF2 activation by Keap1 (show KEAP1 ELISA Kits) knockdown alleviates multiple-organ inflammation and improves the survival rate of Sf mice.

  7. Hypoactivity of NRF2 in Krt16 (show KRT16 ELISA Kits)-/- footpad skin correlated with decreased levels or activity of upstream NRF2 activators.

  8. Lack of Nrf2 enhances susceptibility to mycotoxin-induced kidney disease. Male mice were more sensitive than females.

  9. This study indicated that MAN can protect osteoblast against oxidative damage by modulation of ERK5 (show MAPK7 ELISA Kits)/Nrf2 signaling, which can be new agent for osteoporosis.

  10. In conclusion, quercetin protected mice from d-galactose-induced cognitive functional impairment and neuronal cell apoptosis via activation of the Nrf2-ARE signaling pathway.

NRF2 (NFE2L2) Antigen Profile

Antigen Summary

This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters\; many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with NRF2 (NFE2L2)

  • nuclear factor (erythroid-derived 2)-like 2a (nfe2l2a) Elisa Kit
  • nuclear factor (erythroid-derived 2)-like 2 (nfe2l2) Elisa Kit
  • nuclear factor (erythroid-derived 2)-like 2 (NFE2L2) Elisa Kit
  • nuclear factor, erythroid 2-like 2 (NFE2L2) Elisa Kit
  • nuclear factor, erythroid derived 2, like 2 (Nfe2l2) Elisa Kit
  • AI194320 Elisa Kit
  • NF-E2R2 Elisa Kit
  • nfe2l2 Elisa Kit
  • NRF2 Elisa Kit
  • wu:fc15g09 Elisa Kit
  • wu:fj67e03 Elisa Kit

Protein level used designations for NFE2L2

Nrf2a , nuclear factor (erythroid-derived 2)-like 2 , nuclear factor erythroid 2-related factor 2 , ECH , NF-E2-related factor 2 , NFE2-related factor 2 , nuclear factor, erythroid derived 2, like 2 , HEBP1 , nuclear factor erythroid-derived 2-like 2 , nrf2 , nuclear factor erythroid 2-like 2

360149 Danio rerio
444736 Xenopus laevis
396014 Gallus gallus
478813 Canis lupus familiaris
497024 Bos taurus
100516343 Sus scrofa
4780 Homo sapiens
18024 Mus musculus
83619 Rattus norvegicus
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