Browse our LAT2 Proteins (LAT2)

Full name:
Linker For Activation of T Cells Family, Member 2 Proteins (LAT2)
On are 23 Linker For Activation of T Cells Family, Member 2 (LAT2) Proteins from 10 different suppliers available. Additionally we are shipping LAT2 Antibodies (177) and LAT2 Kits (1) and many more products for this protein. A total of 211 LAT2 products are currently listed.
AW125574, BG:DS00004.9, CG1264, Dmel\\CG1264, Dmlab, Dm lab, EfR9, F24, F90, F90-2, F121, l(3)01241, l(3)84Ac, LAB, LAT2, lb, MGC139435, Ntal, Wbscr5, Wbscr15, WSCR5
list all proteins Gene Name GeneID UniProt
LAT2 7462 Q9GZY6
LAT2 56743 Q9JHL0
LAT2 317676 Q8CGL2

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LAT2 Proteins (LAT2) by Origin

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Top referenced LAT2 Proteins

  1. Human LAT2 Protein expressed in Escherichia coli (E. coli) - ABIN666998 : Iwaki, Jensen, Gilfillan: Ntal/Lab/Lat2. in The international journal of biochemistry & cell biology 2007 (PubMed)
    Show all 2 references for 666998

More Proteins for LAT2 Interaction Partners

Fruit Fly (Drosophila melanogaster) Linker For Activation of T Cells Family, Member 2 (LAT2) interaction partners

  1. labial protein (show HOXD1 Proteins) was expressed in adult labk3/labvd1 copper cells, but not in larvae

  2. Labial, Ultrabithorax, Antennapedia, Extradenticle and Homothorax (show MEIS1 Proteins) are regulated in a signal transduction pathway in developing Drosophila brain

Human Linker For Activation of T Cells Family, Member 2 (LAT2) interaction partners

  1. LAT1 (show LAT Proteins) and LAT2 were overexpressed in both pheochromocytoma and medullary thyroid carcinoma by comparison with normal tissues.

  2. The detergent-induced stabilization of the purified human 4F2hc (show SLC3A2 Proteins)-LAT2 complex presented here paves the way towards its crystallization and structure determination at high-resolution

  3. The AML1 (show RUNX1 Proteins)/ETO (show RUNX1T1 Proteins) target gene LAT2 interferes with differentiation of normal hematopoietic precursor cells.

  4. LAT2 is an early mediator of the anti-leukemic activity of alkylphospholipids and arsenic trioxide. Thus, LAT2 may be used as a target for the design of drugs for cancer therapy.

  5. NTAL acts as a tumor suppressor that enhances the proximal signaling of leukemic blasts. The key downstream molecule responsible for the biological effect of TCR signaling is ERK (show EPHB2 Proteins).

  6. LAT2 protein (NTAL) participates in the activation of the c-Met-Grb2 (show GRB2 Proteins)-ERK (show EPHB2 Proteins)-cPLA2 (show PLA2G4A Proteins) signalling cascade at early stages of H. pylori infection.

  7. data show that NTAL (non-T cell activation linker) appears to be a structural and possibly also functional homologue of LAT (linker for activation of T cells (show LAT Proteins))in non-T cells [non-T cell activation linker]

  8. LAB links BCR (show BCR Proteins) engagement to downstream signaling pathways.

  9. LAB was primarily phosphorylated on three membrane-distal tyrosines, Tyr (show TYR Proteins)(136), Tyr (show TYR Proteins)(193), and Tyr (show TYR Proteins)(233). Mutation of these three tyrosines abolished Grb2 (show GRB2 Proteins) binding and LAB function

  10. LAB resembled a LAT (show ORC3 Proteins) molecule unable to bind phospholipase C (show PLC Proteins)-gamma1.

Mouse (Murine) Linker For Activation of T Cells Family, Member 2 (LAT2) interaction partners

  1. NTAL is a negative regulator of FcepsilonRI (show FCER1A Proteins) activation events in murine bone marrow-derived mast cells, independently of possible compensatory developmental alterations.

  2. Cerebral cortex hyperthyroidism of newborn mct8 (show MCT8 Proteins)-deficient mice transiently suppressed by lat2 (show SLC7A8 Proteins) inactivation.

  3. Our data define a novel link between LAB and beta-catenin (show CTNNB1 Proteins) nuclear accumulation in dendritic cells that facilitates IFN-gamma (show IFNG Proteins) responses during anti-fungal immunity

  4. chemotaxis toward antigen is controlled in mast cells by a cross-talk among FcepsilonRI (show FCER1A Proteins), tetraspanin CD9 (show CD9 Proteins), transmembrane adaptor proteins NTAL and LAT (show LAT Proteins), and cytoskeleton-regulatory proteins of the ERM (show ETV5 Proteins) family

  5. Dihydrotestosterone treatment increased the expression of LAT2 (show SLC7A8 Proteins).

  6. The expression of Mct8 and L-type amino acid transporters Lat2 and Lat1 are determined in brain neurons during development.

  7. a crucial role of NTAL in signaling, via RhoA (show RHOA Proteins), to mast cell cytoskeleton.

  8. While SLP-76 (show LCP2 Proteins) and LAT1 depend on each other for many of their functions, LAT2 (show SLC7A8 Proteins)/SLP-76 (show LCP2 Proteins) interactions and SLP-76 (show LCP2 Proteins)-independent LAT1 functions also mediate a positive signaling pathway downstream of FcepsilonRI (show FCER1A Proteins) in mast cells.

  9. LAB is a critical, LAT (show LAT Proteins)-independent regulator of TREM-2 (show TREM2 Proteins) signaling and macrophage development capable of controlling subsequent inflammatory responses

  10. NTAL negatively regulates Fc-epsilon receptor I-mediated signaling events in bone marrow-derived mast cells.

LAT2 Protein Profile

Protein Summary

This gene is one of the contiguous genes at 7q11.23 commonly deleted in Williams syndrome, a multisystem developmental disorder. This gene consists of at least 14 exons, and its alternative splicing generates 3 transcript variants, all encoding the same protein.

Alternative names and synonyms associated with LAT2

  • labial (lab)
  • linker for activation of T cells family, member 2 (LAT2)
  • linker for activation of T cells family, member 2 (Lat2)
  • AW125574 protein
  • BG:DS00004.9 protein
  • CG1264 protein
  • Dmel\\CG1264 protein
  • Dmlab protein
  • Dm lab protein
  • EfR9 protein
  • F24 protein
  • F90 protein
  • F90-2 protein
  • F121 protein
  • l(3)01241 protein
  • l(3)84Ac protein
  • LAB protein
  • LAT2 protein
  • lb protein
  • MGC139435 protein
  • Ntal protein
  • Wbscr5 protein
  • Wbscr15 protein
  • WSCR5 protein

Protein level used designations for LAT2

CG1264-PA , CG1264-PB , lab-PA , lab-PB , linker for activation of T cells family, member 2 , L-type amino acid transporter subunit , Williams-Beuren syndrome chromosomal region 15 protein , Williams-Beuren syndrome chromosomal region 5 protein , linker for activation of B-cells , linker for activation of T cells, transmembrane adaptor 2 , linker for activation of T-cells family member 2 , membrane-associated adapter molecule , non-T-cell activation linker , Williams-Beuren syndrome chromosome region 15 homolog , Williams-Beuren syndrome chromosome region 5 homolog , non-T cell activation linker , williams-Beuren syndrome chromosomal region 15 protein homolog , Williams-Beuren syndrome chromosome region 5-like protein

40817 Drosophila melanogaster
443250 Ovis aries
505016 Bos taurus
607740 Canis lupus familiaris
7462 Homo sapiens
56743 Mus musculus
317676 Rattus norvegicus
417489 Gallus gallus
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