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Browse our VAV2 (VAV2) ELISA Kits

Full name:
Vav 2 Guanine Nucleotide Exchange Factor ELISA Kits (VAV2)
On www.antibodies-online.com are 5 Vav 2 Guanine Nucleotide Exchange Factor (VAV2) ELISA Kits from 3 different suppliers available. Additionally we are shipping VAV2 Antibodies (82) and and many more products for this protein. A total of 97 VAV2 products are currently listed.
Synonyms:
2810040F13Rik, AI847175, VAV-2
list all ELISA KIts Gene Name GeneID UniProt
VAV2 7410 P52735
Rat VAV2 VAV2 296603  
VAV2 22325 Q60992

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VAV2 (VAV2) ELISA Kits by Reactivity

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Human Vav 2 Guanine Nucleotide Exchange Factor (VAV2) interaction partners

  1. The crystal structure of the complex between a phosphorylated PPxY motif of TXNIP (show TXNIP ELISA Kits) and the SH2 domain of Vav2 reveals a conserved recognition mechanism.

  2. Our data provide the first evidence to implicate VAV2 in glucose-induced Rac1 activation, actin remodelling and glucose-stimulated insulin (show INS ELISA Kits) secretion in pancreatic beta cells.

  3. VAV2 is required for Met signaling in the perinuclear endosome.

  4. Authors propose a model whereby vimentin (show VIM ELISA Kits) promotes FAK (show PTK2 ELISA Kits) stabilization through VAV2-mediated Rac1 activation. This model may explain why vimentin (show VIM ELISA Kits) expressing metastatic lung cancer cells are more motile and invasive.

  5. Data suggest a coordination between paxillin (show PXN ELISA Kits) kinase linker (PKL (show PKLR ELISA Kits))/Vav2 signaling and PKL (show PKLR ELISA Kits)/beta-PIX (show ARHGEF7 ELISA Kits) signaling during cell migration.

  6. the guanine nucleotide exchange factor (show RASGRF1 ELISA Kits) (GEF) Vav2 is identified as a candidate partner for KCC3 (show SLC12A6 ELISA Kits).

  7. Two variants of VAV2 and VAV3 (show VAV3 ELISA Kits), rs2156323 and rs2801219, respectively, were identified in Japanese patients with primary open angle glaucoma, normal tension glaucoma, and developmental glaucoma.

  8. Upregulation of Rac1 activity by Wnt3a (show WNT3A ELISA Kits) temporally correlated with enhanced p120-catenin (show CTNND1 ELISA Kits) binding to Rac1 and Vav2.

  9. Studies indicate relevance of P-Rex1 (show PREX1 ELISA Kits) and P-Rex2a, in breast tumorigenesis, and suggest that the exchange factors Vav2 and Vav3 (show VAV3 ELISA Kits) play synergistic roles in breast cancer by sustaining tumor growth, neoangiogenesis, and metastasis.

  10. Data indicate that Vav2 and Vav3 (show VAV3 ELISA Kits) controlled a vast transcriptional program in breast cancer cells through mechanisms that were shared between the two proteins, isoform-specific or synergistic.

Mouse (Murine) Vav 2 Guanine Nucleotide Exchange Factor (VAV2) interaction partners

  1. Results show that Vav2 and Rac1 are commonly involved in blood pressure regulation.

  2. Data demonstrate that the co-expression of the exchange factors Vav2 and Vav3 (show VAV3 ELISA Kits) is critical for the development of this tumor type.

  3. Vav2 and Vav3 (show VAV3 ELISA Kits) are required for normal peripheral nerve degeneration/regeneration, revascularization and functional recovery.

  4. The results indicate that ADIP (show SSX2IP ELISA Kits) plays an essential role in PDGF (show PDGFA ELISA Kits)-induced cell movement by interacting with afadin (show MLLT4 ELISA Kits) and Vav2 and regulating the activation of Rac (show AKT1 ELISA Kits).

  5. CD36 (show CD36 ELISA Kits) contributes to activation of Vav-1 (show VAV1 ELISA Kits), -2, and -3 in aortae from hyperlipidemic mice

  6. Cbl (show CBL ELISA Kits) ubiquitin ligase (show RNF123 ELISA Kits) plays a critical role in the maintenance of AJs and suppression of cell migration through down-regulation of EGFR (show EGFR ELISA Kits)-Vav2 signaling.

  7. Data show that Vav2/Vav3 (show VAV3 ELISA Kits)-deficient mice show early onset of iridocorneal angle changes and elevated intraocular pressure, with subsequent selective loss of retinal ganglion cells and optic nerve head cupping, which are the hallmarks of glaucoma.

  8. Vav2 controls nitric oxide-dependent responses in mouse vascular smooth muscle cells.

  9. does not contribute to platelet aggregation by CRP (show CRP ELISA Kits) and thrombin (show F2 ELISA Kits), and is not required for regulation of phospholipase C (show PLC ELISA Kits).

  10. Vav2 and Tiam1 may act as downstream effectors of Src (show SRC ELISA Kits), thereby regulating Rac1-dependent pathways that participate in Src (show SRC ELISA Kits)-induced cell transformation

VAV2 Antigen Profile

Antigen Summary

VAV2 is the second member of the VAV guanine nucleotide exchange factor family of oncogenes. Unlike VAV1, which is expressed exclusively in hematopoietic cells, VAV2 transcripts were found in most tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with VAV2

  • vav 2 guanine nucleotide exchange factor (VAV2) Elisa Kit
  • vav 2 guanine nucleotide exchange factor (Vav2) Elisa Kit
  • vav 2 oncogene (Vav2) Elisa Kit
  • 2810040F13Rik Elisa Kit
  • AI847175 Elisa Kit
  • VAV-2 Elisa Kit

Protein level used designations for VAV2

guanine nucleotide exchange factor VAV2 , vav 2 oncogene , Vav2 oncogene , VAV-2

GENE ID SPECIES
7410 Homo sapiens
608060 Canis lupus familiaris
296603 Rattus norvegicus
100151931 Sus scrofa
515718 Bos taurus
22325 Mus musculus
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